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    Therapy control based on a patient movement state
    2.
    发明授权
    Therapy control based on a patient movement state 有权
    基于患者运动状态的治疗控制

    公开(公告)号：US08554325B2

    公开(公告)日：2013-10-08

    申请号：US13345397

    申请日：2012-01-06

    申请人： Gregory F. Molnar ,  Steven S. Gill ,  Keith A. Miesel ,  Mark S. Lent ,  Timothy J. Denison ,  Eric J. Panken ,  Carl D. Wahlstrand ,  Jonathan C. Werder

    发明人： Gregory F. Molnar ,  Steven S. Gill ,  Keith A. Miesel ,  Mark S. Lent ,  Timothy J. Denison ,  Eric J. Panken ,  Carl D. Wahlstrand ,  Jonathan C. Werder

    IPC分类号： A61N1/18

    CPC分类号： A61B5/04014 ,  A61B5/0006 ,  A61B5/4082 ,  A61B5/6814 ,  A61N1/36003 ,  A61N1/36014 ,  A61N1/36025 ,  A61N1/36067 ,  A61N1/36082

    摘要： A movement state of a patient is detected based on brain signals, such as an electroencephalogram (EEG) signal. In some examples, a brain signal within a dorsal-lateral prefrontal cortex of a brain of the patient indicative of prospective movement of the patient may be sensed in order to detect the movement state. The movement state may include the brain state that indicates the patient is intending on initiating movement, initiating movement, attempting to initiate movement or is actually moving. In some examples, upon detecting the movement state, a movement disorder therapy is delivered to the patient. In some examples, the therapy delivery is deactivated upon detecting the patient is no longer in a movement state or that the patient has successfully initiated movement. In addition, in some examples, the movement state detected based on the brain signals may be confirmed based on a signal from a motion sensor.

    摘要翻译： 基于诸如脑电图（EEG）信号的脑信号检测患者的运动状态。 在一些示例中，可以检测指示患者的预期运动的患者的脑的背侧前额叶皮层内的脑信号，以便检测运动状态。 运动状态可以包括指示患者打算启动运动，启动运动，尝试启动运动或实际运动的脑状态。 在一些示例中，在检测到运动状态时，将运动障碍治疗递送给患者。 在一些示例中，在检测到患者不再处于运动状态或患者已成功启动运动时，治疗递送被停用。 此外，在一些示例中，可以基于来自运动传感器的信号来确认基于脑信号检测到的运动状态。

    THERAPY CONTROL BASED ON A PATIENT MOVEMENT STATE
    4.
    发明申请
    THERAPY CONTROL BASED ON A PATIENT MOVEMENT STATE 有权
    基于患者运动状态的治疗控制

    公开(公告)号：US20090099627A1

    公开(公告)日：2009-04-16

    申请号：US12237799

    申请日：2008-09-25

    申请人： Gregory F. Molnar ,  Steven S. Gill ,  Keith A. Miesel ,  Mark S. Lent ,  Timothy J. Denison ,  Eric J. Panken ,  Carl D. Wahlstrand ,  Jonathan C. Werder

    发明人： Gregory F. Molnar ,  Steven S. Gill ,  Keith A. Miesel ,  Mark S. Lent ,  Timothy J. Denison ,  Eric J. Panken ,  Carl D. Wahlstrand ,  Jonathan C. Werder

    IPC分类号： A61N1/36 ,  A61B5/0476 ,  A61M37/00

    CPC分类号： A61B5/04014 ,  A61B5/0006 ,  A61B5/4082 ,  A61B5/6814 ,  A61N1/36003 ,  A61N1/36014 ,  A61N1/36025 ,  A61N1/36067 ,  A61N1/36082

    摘要： A movement state of a patient is detected based on brain signals, such as an electroencephalogram (EEG) signal. In some examples, a brain signal within a dorsal-lateral prefrontal cortex of a brain of the patient indicative of prospective movement of the patient may be sensed in order to detect the movement state. The movement state may include the brain state that indicates the patient is intending on initiating movement, initiating movement, attempting to initiate movement or is actually moving. In some examples, upon detecting the movement state, a movement disorder therapy is delivered to the patient. In some examples, the therapy delivery is deactivated upon detecting the patient is no longer in a movement state or that the patient has successfully initiated movement. In addition, in some examples, the movement state detected based on the brain signals may be confirmed based on a signal from a motion sensor.

    摘要翻译： 基于诸如脑电图（EEG）信号的脑信号检测患者的运动状态。 在一些示例中，可以检测指示患者的预期运动的患者的脑的背侧前额叶皮层内的脑信号，以便检测运动状态。 运动状态可以包括指示患者打算启动运动，启动运动，尝试启动运动或实际运动的脑状态。 在一些示例中，在检测到运动状态时，将运动障碍治疗递送给患者。 在一些示例中，在检测到患者不再处于运动状态或患者已经成功启动运动时，治疗递送被停用。 此外，在一些示例中，可以基于来自运动传感器的信号来确认基于脑信号检测到的运动状态。

    Therapy control based on a patient movement state
    5.
    发明授权
    Therapy control based on a patient movement state 有权
    基于患者运动状态的治疗控制

    公开(公告)号：US08121694B2

    公开(公告)日：2012-02-21

    申请号：US12237799

    申请日：2008-09-25

    申请人： Gregory F. Molnar ,  Steven S. Gill ,  Keith A. Miesel ,  Mark S. Lent ,  Timothy J. Denison ,  Eric J. Panken ,  Carl D. Wahlstrand ,  Jonathan C. Werder

    发明人： Gregory F. Molnar ,  Steven S. Gill ,  Keith A. Miesel ,  Mark S. Lent ,  Timothy J. Denison ,  Eric J. Panken ,  Carl D. Wahlstrand ,  Jonathan C. Werder

    IPC分类号： A61N1/18

    CPC分类号： A61B5/04014 ,  A61B5/0006 ,  A61B5/4082 ,  A61B5/6814 ,  A61N1/36003 ,  A61N1/36014 ,  A61N1/36025 ,  A61N1/36067 ,  A61N1/36082

    摘要： A movement state of a patient is detected based on brain signals, such as an electroencephalogram (EEG) signal. In some examples, a brain signal within a dorsal-lateral prefrontal cortex of a brain of the patient indicative of prospective movement of the patient may be sensed in order to detect the movement state. The movement state may include the brain state that indicates the patient is intending on initiating movement, initiating movement, attempting to initiate movement or is actually moving. In some examples, upon detecting the movement state, a movement disorder therapy is delivered to the patient. In some examples, the therapy delivery is deactivated upon detecting the patient is no longer in a movement state or that the patient has successfully initiated movement. In addition, in some examples, the movement state detected based on the brain signals may be confirmed based on a signal from a motion sensor.

    摘要翻译： 基于诸如脑电图（EEG）信号的脑信号检测患者的运动状态。 在一些示例中，可以检测指示患者的预期运动的患者的脑的背侧前额叶皮层内的脑信号，以便检测运动状态。 运动状态可以包括指示患者打算启动运动，启动运动，尝试启动运动或实际运动的脑状态。 在一些示例中，在检测到运动状态时，将运动障碍治疗递送给患者。 在一些示例中，在检测到患者不再处于运动状态或患者已成功启动运动时，治疗递送被停用。 此外，在一些示例中，可以基于来自运动传感器的信号来确认基于脑信号检测到的运动状态。

    Patient directed therapy control
    6.
    发明申请
    Patient directed therapy control 有权
    患者定向治疗控制

    公开(公告)号：US20090082829A1

    公开(公告)日：2009-03-26

    申请号：US11974931

    申请日：2007-10-16

    申请人： Eric J. Panken ,  Timothy J. Denison ,  Gregory F. Molnar

    发明人： Eric J. Panken ,  Timothy J. Denison ,  Gregory F. Molnar

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36139 ,  A61B5/048 ,  A61B5/4082 ,  A61B5/7475 ,  A61M5/14276 ,  A61M5/1723 ,  A61M2210/0693 ,  A61N1/36014 ,  A61N1/36017 ,  A61N1/36021 ,  A61N1/36025 ,  A61N1/3605 ,  A61N1/3606 ,  A61N1/36071 ,  A61N1/36082 ,  A61N1/37252 ,  G06F3/015

    摘要： A patient controls the delivery of therapy through volitional inputs that are detected by a biosignal within the brain. The volitional patient input may be directed towards performing a specific physical or mental activity, such as moving a muscle or performing a mathematical calculation. In one embodiment, a biosignal detection module monitors an electroencephalogram (EEG) signal from within the brain of the patient and determines whether the EEG signal includes the biosignal. In one embodiment, the biosignal detection module analyzes one or more frequency components of the EEG signal. In this manner, the patient may adjust therapy delivery by providing a volitional input that is detected by brain signals, wherein the volitional input may not require the interaction with another device, thereby eliminating the need for an external programmer to adjust therapy delivery. Example therapies include electrical stimulation, drug delivery, and delivery of sensory cues.

    摘要翻译： 患者通过由大脑内的生物信号检测到的输入量来控制治疗的传递。 患者的输入可以指向执行特定的身体或精神活动，例如移动肌肉或执行数学计算。 在一个实施例中，生物信号检测模块监测来自患者脑内的脑电图（EEG）信号，并确定EEG信号是否包括生物信号。 在一个实施例中，生物信号检测模块分析EEG信号的一个或多个频率分量。 以这种方式，患者可以通过提供由脑信号检测到的输入量来调节治疗递送，其中，该输入可能不需要与另一个装置的相互作用，从而消除了外部程序员调整治疗递送的需要。 示例治疗包括电刺激，药物递送和感觉线索的递送。

    THERAPY PROGRAM SELECTION
    9.
    发明申请
    THERAPY PROGRAM SELECTION 有权
    治疗方案选择

    公开(公告)号：US20090105785A1

    公开(公告)日：2009-04-23

    申请号：US12238025

    申请日：2008-09-25

    申请人： Xuan Wei ,  Richard T. Stone ,  Timothy J. Denison ,  Gregory F. Molnar

    发明人： Xuan Wei ,  Richard T. Stone ,  Timothy J. Denison ,  Gregory F. Molnar

    IPC分类号： A61N1/02 ,  A61B5/00 ,  A61B5/0476 ,  G08B21/00 ,  A61M31/00 ,  A61B5/0488

    CPC分类号： A61N1/36542 ,  A61N1/36132 ,  A61N1/36135 ,  A61N1/37 ,  G06F19/00 ,  G06F19/3481

    摘要： A therapy program is selected based on a patient state, where the patient state comprises at least one of a movement state, sleep state or speech state. In this way, therapy delivery is tailored to the patient state, which may include specific patient symptoms. The therapy program is selected from a plurality of stored therapy programs that comprise therapy programs associated with a respective one at least two of the movement, sleep, and speech states. Techniques for determining a patient state include receiving volitional patient input or detecting biosignals generated within the patient's brain. The biosignals are nonsymptomatic and may be incidental to the movement, sleep, and speech states or generated in response to volitional patient input.

    摘要翻译： 基于患者状态选择治疗程序，其中患者状态包括运动状态，睡眠状态或语音状态中的至少一个。 以这种方式，治疗递送是针对患者状态而定制的，其可以包括特定的患者症状。 治疗程序选自包括与运动，睡眠和言语状态中的至少两个相关的治疗程序的多个存储的治疗程序。 用于确定患者状态的技术包括接收患者输入或检测患者大脑内生成的生物信号。 生物信号是无症状的，可能与运动，睡眠和言语状态有关，或者是响应于患者输入的意图产生的。

    Therapy program selection based on patient state
    10.
    发明授权
    Therapy program selection based on patient state 有权
    基于患者状态的治疗方案选择

    公开(公告)号：US08290596B2

    公开(公告)日：2012-10-16

    申请号：US12238025

    申请日：2008-09-25

    申请人： Xuan Wei ,  Richard T. Stone ,  Timothy J. Denison ,  Gregory F. Molnar

    发明人： Xuan Wei ,  Richard T. Stone ,  Timothy J. Denison ,  Gregory F. Molnar

    IPC分类号： A61N1/36

    CPC分类号： A61N1/36542 ,  A61N1/36132 ,  A61N1/36135 ,  A61N1/37 ,  G06F19/00 ,  G06F19/3481

    摘要： A therapy program is selected based on a patient state, where the patient state comprises at least one of a movement state, sleep state or speech state. In this way, therapy delivery is tailored to the patient state, which may include specific patient symptoms. The therapy program is selected from a plurality of stored therapy programs that comprise therapy programs associated with a respective one at least two of the movement, sleep, and speech states. Techniques for determining a patient state include receiving volitional patient input or detecting biosignals generated within the patient's brain. The biosignals are nonsymptomatic and may be incidental to the movement, sleep, and speech states or generated in response to volitional patient input.

    摘要翻译： 基于患者状态选择治疗程序，其中患者状态包括运动状态，睡眠状态或语音状态中的至少一个。 以这种方式，治疗递送是针对患者状态而定制的，其可以包括特定的患者症状。 治疗程序选自包括与运动，睡眠和言语状态中的至少两个相关的治疗程序的多个存储的治疗程序。 用于确定患者状态的技术包括接收患者输入或检测患者大脑内生成的生物信号。 生物信号是无症状的，可能与运动，睡眠和言语状态有关，或者是响应于患者输入的意图产生的。