公开(公告)号：US20120035642A1

公开(公告)日：2012-02-09

申请号：US13255195

申请日：2010-03-09

申请人： John O'dea ,  Adrian McHugh ,  Eoin Bambury

发明人： John O'dea ,  Adrian McHugh ,  Eoin Bambury

IPC分类号： A61M29/00

CPC分类号： A61B5/1076 ,  A61B5/42 ,  A61B5/4238 ,  A61B5/6853 ,  A61F5/0063 ,  A61F2005/002 ,  A61M25/10 ,  A61M25/1002 ,  A61M25/1018 ,  A61M25/10184 ,  A61M25/10187 ,  A61M2025/0002 ,  A61M2025/1086 ,  A61M2025/1088 ,  A61M2025/1093 ,  A61M2210/1064

摘要： A balloon catheter (1) comprises a catheter (2) and a balloon (6) located on the distal end of the catheter. A pair of stimulating electrodes (15) for receiving a constant current stimulating signal when the balloon (6) is inflated with an electrically conductive medium and a plurality of sensing electrodes (16) for producing voltage response signals are located on the catheter (2). The voltage response signals are indicative of the values of the transverse cross-sectional area of the balloon (6) adjacent the sensing electrodes (16). A first lumen

摘要翻译： 气囊导管（1）包括导管（2）和位于导管远端的球囊（6）。 一对刺激电极（15）位于导管（2）上，用于在气球（6）用导电介质充气时接收恒流刺激信号，并且多个感测电极（16）用于产生电压响应信号， 。 电压响应信号表示与感测电极（16）相邻的球囊（6）的横截面积的值。 第一腔<9）容纳充气介质往上和离开球囊（6），第二腔（19）容纳导电线（18）到刺激和感测电极（15,16）。 压力传感器（21）位于第二内腔（19）中的保护壳体（22）中，并且通过保护壳体（22）中的连通开口（26）并且通过连通口（24）连通 导管（2），其具有球囊（6）的中空内部区域（7）。

公开(公告)号：US20100094328A1

公开(公告)日：2010-04-15

申请号：US12444985

申请日：2008-06-27

申请人： John O'dea ,  Adrian Mchugh ,  Patrick Griffin

发明人： John O'dea ,  Adrian Mchugh ,  Patrick Griffin

IPC分类号： A61M29/02

CPC分类号： A61M25/10181 ,  A61B5/0538 ,  A61B5/1076 ,  A61B5/4233 ,  A61B5/6853 ,  A61M25/1002 ,  A61M25/1011 ,  A61M25/10187 ,  A61M29/02 ,  A61M2025/1059

摘要： A system (1) for dilating an occlusion (3) in an oesophagus (4) comprises a device (5) having a catheter (8) extending from a proximal end (9) to a distal end (10). An inflatable balloon (12) defining a hollow interior region (14) is located on the catheter (8) adjacent the distal end (10) thereof for dilating the occlusion (3). The balloon (12) is inflated with a saline solution by a pump (34) through an axial communicating bore (20) and radial communicating bores (21) in the catheter (8). A pair of stimulating electrodes (25) on the catheter (8) within the balloon (12) adjacent axially opposite ends (18,19) thereof receive stimulating voltage signals from a signal generator (43). Receiving electrodes (28) on the catheter (8) between the stimulating electrodes (25) produce resulting voltage signals in response to the stimulating current signal on the stimulating electrodes (25) which are indicative of the transverse cross-sectional area of the balloon (12) adjacent the receiving electrodes (28) when the balloon (12) is inflated with the saline solution. A microprocessor (35) determines the diameter of the balloon (12) at the receiving electrodes (28) from the resulting signals thereon, and displays a three-dimensional image (46) of the balloon (12) on a visual display screen (47) as well as the corresponding diameter values in windows (48) on the visual display screen (47). A surgeon observes an image of the balloon (12) which corresponds to an image of the occlusion (3) and adjacent portion of the oesophagus 4) during dilating of the occlusion (3).

摘要翻译： 用于扩张食管（4）中的闭塞（3）的系统（1）包括具有从近端（9）延伸到远端（10）的导管（8）的装置（5）。 限定中空内部区域（14）的可膨胀气囊（12）位于邻近其远端（10）的导管（8）上，用于扩张闭塞（3）。 气囊（12）通过泵（34）通过轴向连通孔（20）和导管（8）中的径向连通孔（21）用盐水溶液充气。 邻近轴向相对端（18,19）的球囊（12）内的导管（8）上的一对刺激电极（25）从信号发生器（43）接收刺激电压信号。 在刺激电极（25）之间的导管（8）上的接收电极（28）响应于刺激电极（25）上的刺激电流信号而产生所产生的电压信号，其表示球囊的横截面积（ 12），当气囊（12）用盐水溶液充气时，邻近接收电极（28）。 微处理器（35）从其上产生的信号确定接收电极（28）处的球囊（12）的直径，并将气球（12）的三维图像（46）显示在视觉显示屏（47）上 ）以及视觉显示屏幕（47）上的窗口（48）中的相应直径值。 外科医生观察气囊（12）的图像，其对应于闭塞（3）扩张期间闭塞（3）和食道4）的相邻部分的图像。

公开(公告)号：US08701664B2

公开(公告)日：2014-04-22

申请号：US10796585

申请日：2004-03-09

申请人： John O'dea

发明人： John O'dea

IPC分类号： A61M16/00

CPC分类号： A61M16/202 ,  A61M16/0069 ,  A61M16/107 ,  A61M16/20 ,  A61M16/205

摘要： Apparatus (1) for relieving dyspnoea in an ambulatory exercising subject comprises a housing (3) to be worn on the subject, and within which a variable speed air blower motor (5) is located for delivering an air supply to the subject through a mouthpiece (10) at a pressure similar to average intrinsic positive end-expiratory pressure of the subject. A pressure transducer (25) in the mouthpiece (10) monitors the pressure during breathing cycles of the subject, and a control circuit (22) determines the average intrinsic positive end-expiratory pressure of the subject over five breathing cycles. The control circuit (22) operates the air blower motor (5) for delivering the air supply to the subject at a pressure similar to the determined average intrinsic positive end-expiratory pressure.

摘要翻译： 用于缓解行走运动对象中的呼吸困难的装置（1）包括：被佩戴在受试者上的壳体（3），并且其中定位有变速鼓风机马达（5），用于通过接口管 （10），其压力类似于受试者的平均内在正常呼气末正压。 吸嘴（10）中的压力传感器（25）监测受试者的呼吸循环期间的压力，并且控制电路（22）确定受试者在五个呼吸周期内的平均内在正常呼气末压力。 控制电路（22）操作鼓风机马达（5），用于以与所确定的平均本征正端呼气压力相似的压力将空气供应输送给受试者。

公开(公告)号：US20120130207A1

公开(公告)日：2012-05-24

申请号：US13266248

申请日：2010-04-29

申请人： John O'dea ,  Eoin Bambury

发明人： John O'dea ,  Eoin Bambury

IPC分类号： A61B5/053 ,  A61B5/145 ,  A61M5/00 ,  A61B5/103

CPC分类号： A61M37/0015 ,  A61M2037/0023 ,  A61M2037/0061 ,  A61M2205/13

摘要： A micro-needle device (3) comprises a micro-needle element (2) which is carried on a strap (14) and is securable around a limb of a subject by the strap (14) with the micro-needle element (2) located at a desired site. A pressure sensor (23) is located between the strap (14) and the micro-needle element (2) for detecting the pressure at which the micro-needle element (2) is urged into engagement with the skin of the subject. An adjustable clasp (18) secures the strap (14) and permits adjustment of the tension in the strap (14) for in turn adjusting the pressure with which the micro-needle element (2) is urged into engagement with the skin of the subject. An electronic control circuit located in a housing (26) mounted on the strap (14) monitors the pressure read by the pressure sensor (23) and operates three light emitting diodes (28,29,30) to indicate the pressures with which the micro-needle element (2) is urged into engagement with the skin of the subject, and also to indicate when the micro-needle element (2) is urged into engagement with the skin of the subject by the strap (14) with micro-needles (5) of the micro-needle element (2) penetrating the skin of the subject to a desired depth.

摘要翻译： 微针装置（3）包括微针元件（2），所述微针元件（2）承载在带（14）上，并且通过所述带（14）与所述微针元件（2）可缠绕在受试者的肢体周围， 位于所需的位置。 压力传感器（23）位于带（14）和微针元件（2）之间，用于检测微针元件（2）被迫与受试者的皮肤接合的压力。 可调扣环（18）固定带子（14）并且允许调节带子（14）中的张力，从而进一步调节微针元件（2）被推动与受试者的皮肤接合的压力 。 位于安装在带子（14）上的壳体（26）中的电子控制电路监测由压力传感器（23）读取的压力，并操作三个发光二极管（28,29,30），以指示微型 - 针头元件（2）被推动与被检体的皮肤接合，并且还指示微针元件（2）何时被带子（14）用微针推动与被检体的皮肤接合 （2）的微针元件（5）穿透受试者的皮肤到期望的深度。

公开(公告)号：US20110264048A1

公开(公告)日：2011-10-27

申请号：US13127287

申请日：2009-11-04

申请人： John O'dea ,  Eoin Bambury

发明人： John O'dea ,  Eoin Bambury

IPC分类号： A61M5/00

CPC分类号： A61M37/0015 ,  A61B17/205 ,  A61B2010/008 ,  A61M2037/0023 ,  A61M2037/003 ,  A61M2037/0038 ,  A61M2037/0053 ,  A61M2037/0061

摘要： A micro-needle delivery device (1) comprises an active substance accommodating layer (17) having active substance accommodating chambers (20) therein, a drive substance accommodating layer (32) having drive substance accommodating chambers (35) therein aligned with the active substance accommodating chambers (20), an activating layer (45) having heating elements (48) aligned with the drive substance accommodating chambers (35) for heating a drive substance therein, and a micro-needle element (8) having a needle support layer (9) and a plurality of micro-needles (12) extending therefrom. A burstable first membrane (22) is located between and sealably secured to the micro-needle element (8) and to the active substance accommodating layer (17) for sealably closing the active substance accommodating chambers (20) at one end. A second stretchable membrane (30) is located between and sealably secured to the drive substance accommodating layer (32) and to the active substance accommodating layer (17) sealably closes the active substance accommodating chambers (20) at the other end, and the drive substance accommodating chambers (35). A third membrane (40) sealably closes the drive substance accommodating chambers (35).

摘要翻译： 微针输送装置（1）包括其中具有活性物质容纳室（20）的活性物质容纳层（17），具有与活性物质对准的驱动物质容纳室（35）的驱动物质容纳层（32） 容纳室（20），具有与用于加热其中的驱动物质的驱动物质容纳室（35）对准的加热元件（48）的活化层（45）和具有针支撑层的微针元件（8） 9）和从其延伸的多个微针（12）。 可爆破的第一膜（22）位于微针元件（8）之间并且可密封地固定到活动物质容纳层（17）上，用于在一端密封地封闭活性物质容纳室（20）。 第二可拉伸膜（30）位于驱动物质容纳层（32）之间并且可密封地固定在驱动物质容纳层（32）上并且活性物质容纳层（17）在另一端密封地封闭活性物质容纳室（20） 物质容纳室（35）。 第三膜（40）密封地封闭驱动物质容纳室（35）。