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公开(公告)号：US20140205578A1
公开(公告)日：2014-07-24
申请号：US14126994
申请日：2012-06-15
申请人： Jonathan D. Powell , Bo Xiao , Paul Worley , Gregg M. Delgoffe , Adam Waickman
发明人： Jonathan D. Powell , Bo Xiao , Paul Worley , Gregg M. Delgoffe , Adam Waickman
IPC分类号： C12N9/64
CPC分类号： C12N9/6445 , A61K38/4853 , C12Q1/37 , C12Y304/21034 , C12Y304/21035 , G01N33/5023 , G01N2333/96455 , G01N2800/042
摘要： Described herein are methods for increasing insulin sensitivity and for treating Diabetes (Type I and Type II). Also described herein are methods for increasing the amount of brown fat in a subject and for treating metabolic disorders, including obesity.
摘要翻译： 本文描述了增加胰岛素敏感性和治疗糖尿病（I型和II型）的方法。 本文还描述了增加受试者中棕色脂肪的量和用于治疗包括肥胖症在内的代谢紊乱的方法。
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公开(公告)号：US20050164344A1
公开(公告)日：2005-07-28
申请号：US11008889
申请日：2004-12-10
申请人： Paul Worley , Jian Tu , Bo Xiao , Daniel Leahy , Jutta Beneken , Anthony Lanahan , Paul Brakeman
发明人： Paul Worley , Jian Tu , Bo Xiao , Daniel Leahy , Jutta Beneken , Anthony Lanahan , Paul Brakeman
CPC分类号： C07K14/47 , A01K2217/05 , A01K2217/075 , A61K38/00
摘要： A method is provided for identifying a compound that modulates a cellualr response associated with Homer and mediated by a cell-surface or an intracellular receptor. A method is further provided for identifying a compound that modulates receptor activated calcium mobilization associated with Homer. A method is provided for identifying a compound that inhibits Homer protein activity based on the crystal structure coordinates of Homer protein binding domain. A method is also provided for identifying a compound that affects the formation of cell surface receptors into clusters. Also provided are nucleic acids encoding Homer proteins as well as Homer proteins, and Homer interacting proteins.
摘要翻译： 提供了一种用于鉴定调节与荷马相关并由细胞表面或细胞内受体介导的细胞因子反应的化合物的方法。 还提供了一种鉴定调节与荷马相关的受体活化钙动员的化合物的方法。 提供了一种基于荷马蛋白结合结构域的晶体结构坐标来鉴定抑制荷马蛋白活性的化合物的方法。 还提供了一种鉴定影响细胞表面受体形成簇的化合物的方法。 还提供了编码荷马蛋白以及荷马蛋白和荷马相互作用蛋白的核酸。
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公开(公告)号：US20210285089A1
公开(公告)日：2021-09-16
申请号：US16819107
申请日：2020-03-15
申请人： Bo Xiao
发明人： Bo Xiao
摘要： The present disclosure relates to a metal nanoparticle sensor and fabrication method thereof. The metal nanoparticle sensor includes a SERS substrate, comprising a substrate, metal oxide nanostructures formed on the substrate, and metal nanoparticles grown on the metal oxide nanostructures. The metal oxide nanostructures include crystal facets. The metal nanoparticles substantially cover the crystal facets and the metal nanoparticles are grown in a vacuum chamber at an elevated substrate temperature.
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公开(公告)号：US20200334445A1
公开(公告)日：2020-10-22
申请号：US16922181
申请日：2020-07-07
申请人： Bo Xiao
发明人： Bo Xiao
IPC分类号： G06K9/00 , G06K9/38 , G01N21/55 , H04N5/225 , G01N21/59 , G06T7/73 , G01N21/552 , H01L27/146
摘要： A sensing method for a nanostructure pixel sensor includes shining light from an incident angle onto a nanostructure pixel sensor; capturing an image of nanostructure pixels of the nanostructure pixel sensor; obtaining brightness values of the nanostructure pixels from the image; and determining a presence and/or amount of an analyte based on an image pattern. The nanostructure pixel sensor includes a plurality of the nanostructure pixels. Each of the nanostructure pixels includes periodic nanostructures. At least two nanostructure pixels have different periodic spacings, and the analyte is applied on the nanostructure pixel sensor before capturing the image.
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公开(公告)号：US10009675B2
公开(公告)日：2018-06-26
申请号：US15416168
申请日：2017-01-26
申请人： Bo Xiao , Ronglin Linghu
发明人： Bo Xiao , Ronglin Linghu
CPC分类号： H04R1/06 , H04R9/025 , H04R9/046 , H04R9/06 , H04R2499/11
摘要： The present invention provides a miniature loudspeaker, including a voice coil. The voice coil includes a voice coil body and four voice coil leads connected to the voice coil body. The voice coil body includes four corners, each of which is provided with a voice coil lead. The four voice coil leads are fixed to the frame and support the voice coil body. Each voice coil lead includes a first connecting portion connected to the voice coil body, a second connecting portion fixed to the frame, and a third connecting portion connecting the first connecting portion and the second connecting portion. The third connecting portion is wound into a helical structure. The voice coil of the miniature loudspeaker provided in the present invention is divided into four voice coil leads, which are respectively disposed at positions of four corners of the voice coil body and are wound into a helical structure to support the voice coil body, such that the voice coil bears even force and vibrates stably in the vibration process, thereby resolving the vibration system swing problem and improving sound quality of the miniature loudspeaker.
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公开(公告)号：US10003887B2
公开(公告)日：2018-06-19
申请号：US15383031
申请日：2016-12-19
申请人： Ronglin Linghu , Bo Xiao
发明人： Ronglin Linghu , Bo Xiao
CPC分类号： H04R9/04 , H04R7/127 , H04R7/20 , H04R9/045 , H04R9/06 , H04R31/003 , H04R2400/11
摘要： A miniature sound generator is disclosed. The miniature sound generator includes a vibration system including a diaphragm and a voice coil arranged below the diaphragm for driving the diaphragm to generate sound, the voice coil having a pair of long axis edges and a pair of short axis edges; a fixing system; and a flexible circuit board elastically supporting the voice coil. The flexible circuit board includes a first fixing part connected with the fixing system, a second fixing part connected to the voice coil, and a plurality of elastic connecting pieces connecting the first fixing part to the second fixing part. The elastic connecting pieces are connected with the long axis edges of the voice coil, and the voice coil is electrically connected with the elastic connecting pieces.
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公开(公告)号：US20170366900A1
公开(公告)日：2017-12-21
申请号：US15383031
申请日：2016-12-19
申请人： Ronglin Linghu , Bo Xiao
发明人： Ronglin Linghu , Bo Xiao
CPC分类号： H04R9/04 , H04R7/127 , H04R7/20 , H04R9/045 , H04R9/06 , H04R31/003 , H04R2400/11
摘要： A miniature sound generator is disclosed. The miniature sound generator includes a vibration system including a diaphragm and a voice coil arranged below the diaphragm for driving the diaphragm to generate sound, the voice coil having a pair of long axis edges and a pair of short axis edges; a fixing system; and a flexible circuit board elastically supporting the voice coil. The flexible circuit board includes a first fixing part connected with the fixing system, a second fixing part connected to the voice coil, and a plurality of elastic connecting pieces connecting the first fixing part to the second fixing part. The elastic connecting pieces are connected with the long axis edges of the voice coil, and the voice coil is electrically connected with the elastic connecting pieces.
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公开(公告)号：US09467759B2
公开(公告)日：2016-10-11
申请号：US14525428
申请日：2014-10-28
CPC分类号： H04R1/025 , H04R1/021 , H04R9/025 , H04R9/045 , H04R9/06 , H04R2201/02 , H04R2400/11 , H04R2499/11
摘要： A speaker box is disclosed. The speaker box includes a housing including a bottom wall, and a speaker unit accommodated in the housing. The speaker unit includes a magnetic circuit unit having a lower plate, a magnet on the lower plate, an upper plate on the magnet, and a magnetic gap. The lower plate abuts against the bottom wall for forming a space communicated with the magnetic gap. Thus, the air pressure in the magnetic gap is balanced, and the low frequency sound performance is improved.
摘要翻译： 公开了一种扬声器箱。 扬声器箱包括壳体，其包括底壁和容纳在壳体中的扬声器单元。 扬声器单元包括具有下板的磁路单元，下板上的磁体，磁体上的上板和磁隙。 下板邻接底壁，形成与磁隙连通的空间。 因此，磁隙中的空气压力平衡，并且提高了低频声音性能。
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公开(公告)号：US20160112804A1
公开(公告)日：2016-04-21
申请号：US14595334
申请日：2015-01-13
申请人： Bo Xiao , Ronglin Linghu , Jinquan Huang
发明人： Bo Xiao , Ronglin Linghu , Jinquan Huang
CPC分类号： H04R9/025 , H01F7/0289
摘要： An magnetic assembly and an electro-acoustic transducer using the same are disclosed. The magnetic assembly includes a lower plate, a main magnet positioned on a central portion of the lower plate, an auxiliary magnet positioned on a periphery portion of the lower plate, surrounding the main magnet with space, and having an inner surface facing the main magnet and an outer surface opposite to the inner surface, and a first pole plate. The first pole plate includes a base body attached on the auxiliary magnet, and a magnetic conduction member connected with the base body and overlapping the outer surface of the auxiliary magnet for forming a loop of magnetic flux together with the base body and the lower plate as well as the auxiliary magnet.
摘要翻译： 公开了一种磁性组件和使用其的电声换能器。 磁性组件包括下板，位于下板的中心部分上的主磁体，位于下板的周边部分上的辅助磁体，围绕主磁体具有空间，并且具有面向主磁体的内表面 和与内表面相对的外表面，以及第一极板。 第一极板包括安装在辅助磁体上的基体和与基体连接并与辅助磁体的外表面重叠的磁导体，用于与基体和下板一起形成磁通环，作为 作为辅助磁铁。
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公开(公告)号：US08081444B2
公开(公告)日：2011-12-20
申请号：US12697219
申请日：2010-01-30
申请人： Bo Xiao , Xiang-Kun Zeng , Zhi-Guo Zhang , Li-Fu Xu
发明人： Bo Xiao , Xiang-Kun Zeng , Zhi-Guo Zhang , Li-Fu Xu
CPC分类号： G06F1/20
摘要： A computer system includes a chassis and an airflow guiding duct. The chassis includes a chassis bottom wall, a chassis front wall and a chassis rear wall. The chassis front wall defines a first ventilation hole, and the chassis rear wall defines a second ventilation hole. A motherboard is secured to the chassis bottom wall between the chassis front wall and the chassis rear wall. A memory card is secured to the motherboard. The airflow guiding duct is secured in the chassis and includes an entrance portion. The entrance portion covers a portion of the memory card, so as to guide airflow. Airflow flows in the chassis via the first ventilation hole, over the memory card, and then out of the chassis via the second ventilation hole.
摘要翻译： 计算机系统包括底盘和气流引导导管。 底盘包括机箱底壁，底盘前壁和底盘后壁。 底盘前壁限定第一通风孔，底盘后壁限定第二通风孔。 主机板固定在机箱前壁和底盘后墙之间的机箱底壁上。 存储卡固定在主板上。 气流引导管固定在底盘中，并包括入口部分。 入口部分覆盖存储卡的一部分，以引导气流。 气流通过第一个通气孔，存储卡上方流过底盘，然后通过第二个通风孔流出机箱。
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