公开(公告)号：US20080148815A1

公开(公告)日：2008-06-26

申请号：US11836736

申请日：2007-08-09

申请人： Jonathan Day Lucas ,  Manna Leon Warburton ,  Todd Mlsna ,  Sanjay V. Patel ,  Stephen Terrence Hobson

发明人： Jonathan Day Lucas ,  Manna Leon Warburton ,  Todd Mlsna ,  Sanjay V. Patel ,  Stephen Terrence Hobson

IPC分类号： G01N1/40

CPC分类号： G01N30/08 ,  G01N2030/085 ,  G01N2030/126

摘要： Apparatus, systems and methods are described for preconcentrators, chemical sensing systems and gas chromatographs. A preconcentrator is described that comprises a hollow enclosure containing a sorbent material. The enclosure may be a capillary tube that can be formed in to a desired shape and that may be heated. Heating may be accomplished by passing an electrical current through the capillary or other hollow enclosure form. The sorbent material can be a liquid, a solid, a porous ceramic material and/or a chemiselective polymer. The sorbent material can be coated to the inner wall of the enclosure. The hollow enclosure may be maintained in an insulated chamber. The preconcentrator acts to concentrate a vapor passed through the preconcentrator to a chemical sensing array that can detect chemicals present in the vapor. A gas passed through the hollow enclosure can provide a chemically concentrated input to a chromatographic column.

摘要翻译： 描述了用于预浓缩器，化学传感系统和气相色谱仪的装置，系统和方法。 描述了一种预浓缩器，其包含含有吸附剂材料的中空外壳。 外壳可以是可以形成为期望形状并且可以被加热的毛细管。 加热可以通过使电流通过毛细管或其它中空的外壳形式来实现。 吸附剂材料可以是液体，固体，多孔陶瓷材料和/或化学选择性聚合物。 吸附剂材料可以涂覆到外壳的内壁。 中空的外壳可以保持在绝缘室中。 预浓缩器用于将通过预浓缩器的蒸汽浓缩到可以检测蒸气中存在的化学物质的化学传感阵列。 通过中空外壳的气体可以向色谱柱提供化学浓度的输入。

公开(公告)号：US20100307224A1

公开(公告)日：2010-12-09

申请号：US12771835

申请日：2010-04-30

申请人： Jonathan Day Lucas ,  Manna Leon Warburton ,  Todd Mlsna ,  Sanjay V. Patel ,  Stephen Terrence Hobson

发明人： Jonathan Day Lucas ,  Manna Leon Warburton ,  Todd Mlsna ,  Sanjay V. Patel ,  Stephen Terrence Hobson

IPC分类号： G01N1/40

CPC分类号： G01N30/08 ,  G01N2030/085 ,  G01N2030/126

摘要： Apparatus, systems and methods are described for preconcentrators, chemical sensing systems and gas chromatographs. A preconcentrator is described that comprises a hollow enclosure containing a sorbent material. The enclosure may be a capillary tube that can be formed in to a desired shape and that may be heated. Heating may be accomplished by passing an electrical current through the capillary or other hollow enclosure form. The sorbent material can be a liquid, a solid, a porous ceramic material and/or a chemiselective polymer. The sorbent material can be coated to the inner wall of the enclosure. The hollow enclosure may be maintained in an insulated chamber. The preconcentrator acts to concentrate a vapor passed through the preconcentrator to a chemical sensing array that can detect chemicals present in the vapor. A gas passed through the hollow enclosure can provide a chemically concentrated input to a chromatographic column.

摘要翻译： 描述了用于预浓缩器，化学传感系统和气相色谱仪的装置，系统和方法。 描述了一种预浓缩器，其包含含有吸附剂材料的中空外壳。 外壳可以是可以形成为期望形状并且可以被加热的毛细管。 加热可以通过使电流通过毛细管或其它中空的外壳形式来实现。 吸附剂材料可以是液体，固体，多孔陶瓷材料和/或化学选择性聚合物。 吸附剂材料可以涂覆到外壳的内壁。 中空的外壳可以保持在绝缘室中。 预浓缩器用于将通过预浓缩器的蒸汽浓缩到可以检测蒸气中存在的化学物质的化学传感阵列。 通过中空外壳的气体可以向色谱柱提供化学浓度的输入。

公开(公告)号：US08333105B2

公开(公告)日：2012-12-18

申请号：US12771835

申请日：2010-04-30

申请人： Jonathan Day Lucas ,  Manna Leon Warburton ,  Todd Mlsna ,  Sanjay V. Patel ,  Stephen Terrence Hobson

发明人： Jonathan Day Lucas ,  Manna Leon Warburton ,  Todd Mlsna ,  Sanjay V. Patel ,  Stephen Terrence Hobson

IPC分类号： G01N30/08

CPC分类号： G01N30/08 ,  G01N2030/085 ,  G01N2030/126

摘要： Apparatus, systems and methods are described for preconcentrators, chemical sensing systems and gas chromatographs. A preconcentrator is described that comprises a hollow enclosure containing a sorbent material. The enclosure may be a capillary tube that can be formed in to a desired shape and that may be heated. Heating may be accomplished by passing an electrical current through the capillary or other hollow enclosure form. The sorbent material can be a liquid, a solid, a porous ceramic material and/or a chemiselective polymer. The sorbent material can be coated to the inner wall of the enclosure. The hollow enclosure may be maintained in an insulated chamber. The preconcentrator acts to concentrate a vapor passed through the preconcentrator to a chemical sensing array that can detect chemicals present in the vapor. A gas passed through the hollow enclosure can provide a chemically concentrated input to a chromatographic column.

摘要翻译： 描述了用于预浓缩器，化学传感系统和气相色谱仪的装置，系统和方法。 描述了一种预浓缩器，其包含含有吸附剂材料的中空外壳。 外壳可以是可以形成为期望形状并且可以被加热的毛细管。 加热可以通过使电流通过毛细管或其它中空的外壳形式来实现。 吸附剂材料可以是液体，固体，多孔陶瓷材料和/或化学选择性聚合物。 吸附剂材料可以涂覆到外壳的内壁。 中空的外壳可以保持在绝缘室中。 预浓缩器用于将通过预浓缩器的蒸汽浓缩到可以检测蒸气中存在的化学物质的化学传感阵列。 通过中空外壳的气体可以向色谱柱提供化学浓度的输入。

公开(公告)号：US08117896B2

公开(公告)日：2012-02-21

申请号：US11836736

申请日：2007-08-09

申请人： Jonathan Day Lucas ,  Manna Leon Warburton ,  Todd Mlsna ,  Sanjay Patel ,  Stephen Terrence Hobson

发明人： Jonathan Day Lucas ,  Manna Leon Warburton ,  Todd Mlsna ,  Sanjay Patel ,  Stephen Terrence Hobson

IPC分类号： G01N30/08

CPC分类号： G01N30/08 ,  G01N2030/085 ,  G01N2030/126

摘要： Apparatus, systems and methods are described for preconcentrators, chemical sensing systems and gas chromatographs. A preconcentrator is described that comprises a hollow enclosure containing a sorbent material. The enclosure may be a capillary tube that can be formed in to a desired shape and that may be heated. Heating may be accomplished by passing an electrical current through the capillary or other hollow enclosure form. The sorbent material can be a liquid, a solid, a porous ceramic material and/or a chemiselective polymer. The sorbent material can be coated to the inner wall of the enclosure. The hollow enclosure may be maintained in an insulated chamber. The preconcentrator acts to concentrate a vapor passed through the preconcentrator to a chemical sensing array that can detect chemicals present in the vapor. A gas passed through the hollow enclosure can provide a chemically concentrated input to a chromatographic column.

公开(公告)号：US20060237310A1

公开(公告)日：2006-10-26

申请号：US11115911

申请日：2005-04-26

申请人： Sanjay Patel ,  Todd Mlsna ,  Erno Klaasen

发明人： Sanjay Patel ,  Todd Mlsna ,  Erno Klaasen

IPC分类号： G01N27/26

CPC分类号： G01N27/226

摘要： The present invention relates to the field of chemical detection. More specifically, the invention provides devices that can detect various target analytes (e.g., chemicals and/or biological materials) present in an environment by adsorption or absorption of the target analyte(s) to or in a chemical sensing material such that an electrical parameter (e.g., capacitance, resistance, etc.) of the chemical sensing material is altered in a manner detectable by circuitry associated with the sensing electrode pair coated with the chemical sensing material. Here, the sensing electrode pair(s) of the devices of the invention are suspended over an inert substrate via one or more posts used to space the electrodes from the substrate.

摘要翻译： 本发明涉及化学检测领域。 更具体地，本发明提供了可以通过吸附或吸收目标分析物到化学感测材料中或在化学感测材料中来检测存在于环境中的各种目标分析物（例如，化学品和/或生物材料）的装置，使得电参数 （例如，电容，电阻等）以与通过化学感测材料涂覆的感测电极对相关联的电路可检测的方式改变。 这里，本发明的器件的感测电极对通过用于将电极从衬底放置的一个或多个柱悬置在惰性衬底上。

公开(公告)号：US20070194406A1

公开(公告)日：2007-08-23

申请号：US11542741

申请日：2006-10-02

申请人： Sanjay Patel ,  Bernd Fruhberger ,  Erno Klaassen ,  Todd Mlsna ,  David Baselt

发明人： Sanjay Patel ,  Bernd Fruhberger ,  Erno Klaassen ,  Todd Mlsna ,  David Baselt

IPC分类号： H01L29/00

CPC分类号： B81C1/00341 ,  B81B2201/0214 ,  B81C1/00182 ,  G01N27/227 ,  H01G5/18

摘要： A fixed parallel plate micro-mechanical systems (MEMS) based sensor is fabricated to allow a dissolved dielectric to flow through a porous top plate, coming to rest on a bottom plate. A post-deposition bake ensures further purity and uniformity of the dielectric layer. In one embodiment, the dielectric is a polymer. In one embodiment, a support layer is deposited onto the top plate for strengthening the sensor. In another embodiment, the bottom plate is dual-layered for a narrowed gap. Integrated circuit arrays of such sensors can be made, having multiple devices separated from each other by a physical barrier, such as a polycrystalline containment rim or trough, for preventing polymer material from one sensor from interfering with that of another.

摘要翻译： 制造基于固定平行板微机械系统（MEMS）的传感器，以使溶解的电介质流过多孔顶板，停留在底板上。 沉积后烘烤确保了电介质层的进一步纯度和均匀性。 在一个实施方案中，电介质是聚合物。 在一个实施例中，支撑层沉积在顶板上以加强传感器。 在另一个实施例中，底板是双层的，用于狭窄的间隙。 可以制造这种传感器的集成电路阵列，其具有通过物理屏障（例如多晶容纳边缘或槽）彼此分离的多个装置，用于防止来自一个传感器的聚合物材料与另一传感器的干扰。

公开(公告)号：US20140073827A1

公开(公告)日：2014-03-13

申请号：US14022077

申请日：2013-09-09

申请人： Philip H. Steele ,  Sanjeev K. Gajjela ,  Todd Mlsna ,  Charles U. Pittman, JR. ,  Fei Yu

发明人： Philip H. Steele ,  Sanjeev K. Gajjela ,  Todd Mlsna ,  Charles U. Pittman, JR. ,  Fei Yu

IPC分类号： C10G3/00

CPC分类号： C10G3/52 ,  C10G3/45 ,  C10G3/46 ,  C10G2300/1014 ,  Y02P30/20

摘要： A method for producing biofuel and other hydrocarbons from bio-oil is disclosed. The method does not require the use of hydrogen derived from fossil fuel.

摘要翻译： 公开了一种从生物油生产生物燃料和其他烃的方法。 该方法不需要使用源自化石燃料的氢。

公开(公告)号：US20050164285A1

公开(公告)日：2005-07-28

申请号：US11082634

申请日：2005-03-18

申请人： Sanjay Patel ,  Bernd Fruhberger ,  Robert Warmack ,  Todd Mlsna ,  David Baselt ,  Erno Klaassen

发明人： Sanjay Patel ,  Bernd Fruhberger ,  Robert Warmack ,  Todd Mlsna ,  David Baselt ,  Erno Klaassen

IPC分类号： G01N27/22 ,  C12Q1/68 ,  C12M1/34

CPC分类号： G01N27/227

摘要： A sensor for determining the presence of an analyte is disclosed comprising a reactive layer disposed between a base plate and a movable plate. The reactive layer is configured to interact with an analyte effecting a change in capacitance between the base plate and movable plate. When the analyte has a polarity or overall Hildebrand solubility parameter that is similar to the reactive layer, the change in capacitance is caused by a swelling of the reactive layer as analyte is absorbed into the reactive layer. This results in a decrease in capacitance. When the analyte has a solubility parameter not near the reactive layer, the absorbed analyte causes the reactive layer's total polarity to increase, an effect that dominates swelling. This causes an increase in capacitance. A capacitive sensing circuit is included for measuring the change in capacitance which is indicative of the analyte exposed to the sensor.

公开(公告)号：US06630560B2

公开(公告)日：2003-10-07

申请号：US09895293

申请日：2001-07-02

申请人： Robert Andrew McGill ,  Eric J. Houser ,  Todd Mlsna

发明人： Robert Andrew McGill ,  Eric J. Houser ,  Todd Mlsna

IPC分类号： C08G7724

CPC分类号： C08G77/24 ,  B01J20/285 ,  C08G77/60 ,  C08L83/16 ,  Y10T428/31663 ,  Y10T436/163333 ,  Y10T436/17

摘要： This invention relates generally to a new class of chemoselective polymer materials. In particular, the invention relates to linear and branched polysiloxane compounds for use in various analytical applications involving sorbent polymer materials, including chromatography, chemical trapping, analyte collection, and chemical sensor applications. These polymers have pendant and terminal aryl, alkyl, alkenyl, and alkynyl groups that are functionalized with halogen substituted alcohol or halogen substituted phenol groups, having the general structure: wherein: n is an integer greater than 1; wherein at least one of R1 and R2 includes an alkyl, alkenyl, alkynyl, or aryl group having at least one halogen substituted alcohol or halogen substituted phenol group attached thereto; wherein any said R1 and R2 aryl groups are attached to said [Si—O—]n, the polymer backbone, directly or through a short hydrocarbon chain; wherein any remaining R1 or R2 group is an alkyl, alkenyl, alkynyl, or aryl group having between one and sixteen carbons; and Z is a polymer end group independently selected from the group consisting of saturated hydrocarbons, unsaturated hydrocarbons, alkyl silanes, aryl silanes, hydroxyl, hydride, alkoxides, halogen substituted alcohol, halogen substituted phenol, and combinations thereof. These polymeric materials are primarily designed to sorb hydrogen bond basic analytes such as organophosphonate esters (nerve agents and precursors) and nitro-substituted compounds (explosives).

摘要翻译： 本发明一般涉及一类新的化学选择性聚合物材料。 特别地，本发明涉及用于涉及吸收剂聚合物材料的各种分析应用中的直链和支链聚硅氧烷化合物，包括色谱法，化学捕获法，分析物收集法和化学传感器应用。 这些聚合物具有侧链和末端芳基，被卤素取代的醇或卤素取代的酚基官能化的烷基，烯基和炔基，其具有以下通式：其中：n是大于1的整数;其中R' 1＆gt;和R 2包括具有至少一个卤素取代的醇或卤素取代的苯酚基团的烷基，烯基，炔基或芳基，其中任何所述R 1和R 2芳基连接到 所述[Si-O-] n，聚合物主链，直接或通过短的烃链;其中任何残留的R 1或R 2基团是具有1至16个的烷基，烯基，炔基或芳基 碳; 和Z是独立地选自饱和烃，不饱和烃，烷基硅烷，芳基硅烷，羟基，氢化物，醇盐，卤素取代的醇，卤素取代的苯酚及其组合的聚合物端基。这些聚合物材料主要设计成 吸附氢键碱性分析物如有机膦酸酯（神经药物和前体）和硝基取代的化合物（爆炸物）。

公开(公告)号：US06435007B1

公开(公告)日：2002-08-20

申请号：US09560578

申请日：2000-04-27

申请人： Dean Smith ,  Todd Mlsna ,  Jeremy Hammond

发明人： Dean Smith ,  Todd Mlsna ,  Jeremy Hammond

IPC分类号： G01N1508

CPC分类号： G01N29/022 ,  G01N7/10 ,  G01N2291/0256 ,  G01N2291/02872 ,  G01N2291/0423 ,  G01N2291/106

摘要： A sensor system that monitors agent breakthrough through a vapor barrier and related test process. The system includes a substantially airtight test chamber for retaining the vapor barrier, which may be formed of one or more layers of one or more materials. A sensor element array placed adjacent to the barrier under test includes elements that are sensitive to one or more agents of interest and elements that are insensitive to such agents. The insensitive elements provide a baseline reference signal that is compared to the output signal of the sensitive elements. As the agent contacts the array, the electrical signal output from the sensitive elements changes in comparison to that of the reference elements. The sensor array is sensitive enough to detect low levels of the agent when the agent passes through the barrier. A control system is used to regulate and monitor environmental conditions within the chamber and to process electrical signals from the sensor array.

摘要翻译： 一种传感器系统，通过蒸汽屏障和相关测试过程来监控代理人的突破。 该系统包括用于保持蒸气阻挡物的基本上气密的测试室，其可以由一个或多个一个或多个材料层形成。 放置在与被测屏障相邻的传感器元件阵列包括对感兴趣的一个或多个感兴趣的元件敏感的元件和对这种试剂不敏感的元件。 不敏感元件提供与敏感元件的输出信号相比较的基准参考信号。 当代理人接触阵列时，从敏感元件输出的电信号与参考元件相比变化。 传感器阵列足够敏感，以便在试剂穿过屏障时检测试剂的低含量。 控制系统用于调节和监测室内的环境条件并处理来自传感器阵列的电信号。