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    Systems and methods for separating high hematocrit red blood cell concentrations
    3.
    发明授权
    Systems and methods for separating high hematocrit red blood cell concentrations 失效
    用于分离高血细胞比容红细胞浓度的系统和方法

    公开(公告)号：US6080322A

    公开(公告)日：2000-06-27

    申请号：US72961

    申请日：1998-05-05

    申请人： Jose C. Deniega ,  Daniel H. Duff

    发明人： Jose C. Deniega ,  Daniel H. Duff

    IPC分类号： A61M1/34 ,  A61M1/26 ,  A61M1/30 ,  B01D21/28 ,  B01D21/30 ,  B01D61/14 ,  B01D61/18 ,  B01D63/06 ,  B01D63/16 ,  B01D21/26 ,  B01D61/00

    CPC分类号： A61M1/30 ,  A61M1/265 ,  A61M1/303 ,  A61M1/306 ,  A61M1/308 ,  A61M1/309 ,  A61M2205/3393 ,  A61M2209/082

    摘要： Blood separation systems and methods utilize a membrane separation device comprising a gap between a microporous membrane and a surface facing the microporous membrane, one of the microporous membrane and the surface being rotatable relative to the other to cause separation of whole blood in the gap into plasma and concentrated red blood cells. The systems and methods include an inlet pump element coupled to the membrane separation device to convey whole blood having a known beginning hematocrit value into the gap for separation. The systems and methods also include a drive element coupled to the membrane separation device to cause rotation of the rotatable one of the microporous membrane and the facing surface. The systems and methods command the inlet pump element and the drive element as a function of the known beginning hematocrit value. This command technique obtains concentrated red blood cells having a high end hematocrit value that remains substantially constant despite variances in the known beginning hematocrit value, and, in particular, when the known beginning hematocrit value is low.

    摘要翻译： 血液分离系统和方法利用膜分离装置，其包括微孔膜与面向微多孔膜的表面之间的间隙，微孔膜和表面之一可相对于另一个旋转，以使间隙中的全血分离成等离子体 和浓红细胞。 该系统和方法包括连接到膜分离装置的入口泵元件，以将具有已知开始血细胞比容值的全血输送到用于分离的间隙中。 所述系统和方法还包括联接到膜分离装置的驱动元件，以引起微孔膜和面向表面中的可旋转的一个旋转。 系统和方法根据已知的开始血细胞比容值命令入口泵元件和驱动元件。 该命令技术获得具有高端血细胞比容值的浓缩红细胞，尽管在已知的开始血细胞比容值中有变化，特别是当已知的开始血细胞比容值低时，其保持基本恒定。

    Systems for separating high hematocrit red blood cell concentrations
    5.
    发明授权
    Systems for separating high hematocrit red blood cell concentrations 失效
    用于分离高血细胞比容红细胞浓度的系统

    公开(公告)号：US5762791A

    公开(公告)日：1998-06-09

    申请号：US512807

    申请日：1995-08-09

    申请人： Jose C. Deniega ,  Daniel H. Duff

    发明人： Jose C. Deniega ,  Daniel H. Duff

    IPC分类号： A61M1/34 ,  A61M1/26 ,  A61M1/30 ,  B01D21/28 ,  B01D21/30 ,  B01D61/14 ,  B01D61/18 ,  B01D63/06 ,  B01D63/16 ,  B01D61/00 ,  B01D61/22

    CPC分类号： A61M1/30 ,  A61M1/265 ,  A61M1/303 ,  A61M1/306 ,  A61M1/308 ,  A61M1/309 ,  A61M2205/3393 ,  A61M2209/082

    摘要： Blood separation systems and methods utilize a membrane separation device comprising a gap between a microporous membrane and a surface facing the microporous membrane, one of the microporous membrane and the surface being rotatable relative to the other to cause separation of whole blood in the gap into plasma and concentrated red blood cells. The systems and methods include an inlet pump element coupled to the membrane separation device to convey whole blood having a known beginning hematocrit value into the gap for separation. The systems and methods also include a drive element coupled to the membrane separation device to cause rotation of the rotatable one of the microporous membrane and the facing surface. The systems and methods command the inlet pump element and the drive element as a function of the known beginning hematocrit value. This command technique obtains concentrated red blood cells having a high end hematocrit value that remains substantially constant despite variances in the known beginning hematocrit value, and, in particular, when the known beginning hematocrit value is low.

    摘要翻译： 血液分离系统和方法利用膜分离装置，其包括微孔膜与面向微多孔膜的表面之间的间隙，微孔膜和表面之一可相对于另一个旋转，以使间隙中的全血分离成等离子体 和浓红细胞。 该系统和方法包括连接到膜分离装置的入口泵元件，以将具有已知开始血细胞比容值的全血输送到用于分离的间隙中。 所述系统和方法还包括联接到膜分离装置的驱动元件，以引起微孔膜和面向表面中的可旋转的一个旋转。 系统和方法根据已知的开始血细胞比容值命令入口泵元件和驱动元件。 该命令技术获得具有高端血细胞比容值的浓缩红细胞，尽管在已知的开始血细胞比容值中有变化，特别是当已知的开始血细胞比容值低时，其保持基本恒定。

    Peristaltic pumping apparatus with tubing organizer
    6.
    发明授权
    Peristaltic pumping apparatus with tubing organizer 失效
    蠕动泵装置与管道组织器

    公开(公告)号：US06186752B1

    公开(公告)日：2001-02-13

    申请号：US08907040

    申请日：1997-08-06

    申请人： Jose C. Deniega ,  Tsuyoshi Matsumoto

    发明人： Jose C. Deniega ,  Tsuyoshi Matsumoto

    IPC分类号： F04B4312

    CPC分类号： A61M1/3621 ,  A61M1/1006 ,  A61M1/1039 ,  A61M1/1041 ,  A61M1/1046 ,  A61M1/1089 ,  A61M2209/08 ,  F04B43/1284 ,  F04B43/1292

    摘要： A pump module includes a peristaltic pump having a pump rotor, a drive mechanism to rotate the rotor, and a tubing clamp adjacent to and separate from the peristaltic pump. A cover is movable between a closed position on the pump module, enclosing both the pump rotor and the tubing clamp, and an opened position spaced from the pump module, exposing both the pump rotor and the tubing clamp. The cover carries a tubing organizer, which holds tubing. The tubing organizer serves, as the cover moves toward the closed position, to orient the tubing in a desired way with the pump rotor and tubing clamp. The tubing organizer also serves, as the cover moves toward the opened position, to orient the tubing away from the pump module.

    摘要翻译： 泵模块包括具有泵转子的蠕动泵，用于使转子旋转的驱动机构和邻近蠕动泵并与蠕动泵分离的管夹。 盖可以在泵模块上的关闭位置之间移动，包围泵转子和管夹，以及与泵模块隔开的打开位置，暴露泵转子和管夹。 盖子带有管道管理器，其保持管道。 油管组织器用作当盖移动到关闭位置时，以泵转子和油管夹具以期望的方式定向油管。 当管盖移动到打开位置时，油管组织器也起作用以将油管远离泵模块定向。

    Safety trocar
    8.
    发明授权
    Safety trocar 失效
    安全套管

    公开(公告)号：US5399167A

    公开(公告)日：1995-03-21

    申请号：US66953

    申请日：1993-05-24

    申请人： Jose C. Deniega

    发明人： Jose C. Deniega

    IPC分类号： A61B17/34 ,  A61B19/00 ,  A61M5/178

    CPC分类号： A61B17/3496 ,  A61B2090/08021

    摘要： A safety trocar is provided which includes a spring-loaded shield that shields the cutting tip of the obturator after the obturator penetrates tissue. The distal end of the shield is hemispheric in profile and contains a slot which conforms to the geometry of the cutting tip. The rounded distal end enables the shield to spring forward to shield the cutting tip as soon as the tip perforates the tissue. A valve is located at the proximal end of the trocar tube to seal the end of the tube. The valve is oriented at an acute angle with respect to the longitudinal axis of the trocar tube. The valve is controllable by an external lever which will hold the valve open or permit it to spring shut. An incremental advancement mechanism cooperates with the obturator to permit only incremental advance of the obturator. Instead of using a discrete shield component the shielding function may be provided by spring-loading the trocar tube itself to spring forward and shield the obturator tip after the tip penetrates tissue.

    摘要翻译： 提供了一种安全套针，其包括弹簧加载的屏蔽件，其在闭孔器穿透组织之后屏蔽封闭器的切割尖端。 屏蔽的远端是半球形的，并且包含符合切割尖端几何形状的槽。 圆形的远端使得护罩能够弹起向前以在尖端穿孔组织时一直屏蔽切割尖端。 阀位于套管针管的近端以密封管的端部。 阀相对于套管针管的纵向轴线成锐角。 阀门可以通过一个外部杠杆来控制，该杠杆可以将阀门打开或者允许其弹簧关闭。 增量升级机制与闭孔器合作，仅允许闭塞器的增量推进。 代替使用离散的屏蔽部件，屏蔽功能可以通过弹簧加载套针管本身来弹簧向前提供，并且在尖端穿透组织之后屏蔽封闭器尖端。

    Safety trocar
    9.
    发明授权
    Safety trocar 失效
    安全套管

    公开(公告)号：US5224952A

    公开(公告)日：1993-07-06

    申请号：US963970

    申请日：1992-10-20

    申请人： Jose C. Deniega ,  Stephen J. Failla

    发明人： Jose C. Deniega ,  Stephen J. Failla

    IPC分类号： A61B17/34 ,  A61B19/00

    CPC分类号： A61B17/3496 ,  A61B2090/08021

    摘要： A safety trocar is provided which includes a spring-loaded shield that shields the cutting tip of the obturator after the obturator penetrates tissue. The distal end of the shield is hemispheric in profile and contains a slot which conforms to the geometry of the cutting tip. The rounded distal end enables the shield to spring forward to shield the cutting tip as soon as the tip perforates the tissue. A valve is located at the proximal end of the trocar tube to seal the end of the tube. The valve is oriented at an acute angle with respect to the longitudinal axis of the trocar tube. The valve is controllable by an external lever which will hold the valve open or permit it to spring shut. An incremental advancement mechanism cooperates with the obturator to permit only incremental advance of the obturator. Instead of using a discrete shield component the shielding function may be provided by spring-loading the trocar tube itself to spring forward and shield the obturator tip after the tip penetrates tissue.

    摘要翻译： 提供了一种安全套针，其包括弹簧加载的屏蔽件，其在闭孔器穿透组织之后屏蔽封闭器的切割尖端。 屏蔽的远端是半球形的，并且包含符合切割尖端几何形状的槽。 圆形的远端使得护罩能够弹起向前以在尖端穿孔组织时一直屏蔽切割尖端。 阀位于套管针管的近端以密封管的端部。 阀相对于套管针管的纵向轴线成锐角。 阀门可以通过一个外部杠杆来控制，该杠杆可以将阀门打开或者允许其弹簧关闭。 增量升级机制与闭孔器合作，仅允许闭塞器的增量推进。 代替使用离散的屏蔽部件，屏蔽功能可以通过弹簧加载套针管本身来弹簧向前提供，并且在尖端穿透组织之后屏蔽封闭器尖端。

    Safety trocar
    10.
    发明授权
    Safety trocar 失效

    公开(公告)号：US5215526A

    公开(公告)日：1993-06-01

    申请号：US700787

    申请日：1991-05-15

    申请人： Jose C. Deniega ,  Stephen J. Failla

    发明人： Jose C. Deniega ,  Stephen J. Failla

    IPC分类号： A61B17/34 ,  A61B19/00

    CPC分类号： A61B17/3496 ,  A61B2090/08021

    摘要： A safety trocar is provided which includes a spring-loaded shield that shields the cutting tip of the obturator after the obturator penetrates tissue. The distal end of the shield is hemispheric in profile and contains a slot which conforms to the geometry of the cutting tip. The rounded distal end enables the shield to spring forward to shield the cutting tip as soon as the tip perforates the tissue. A valve is located at the proximal end of the trocar tube to seal the end of the tube. The valve is oriented at an acute angle with respect to the longitudinal axis of the trocar tube. The valve is controllable by an external lever which will hold the valve open or permit it to spring shut. An incremental advancement mechanism cooperates with the obturator to permit only incremental advance of the obturator. Instead of using a discrete shield component the shielding function may be provided by spring-loading the trocar tube itself to spring forward and shield the obturator tip after the tip penetrates tissue.