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1.发明授权Catheters and related devices for forming passageways between blood vessels or other anatomical structures 有权用于在血管或其他解剖结构之间形成通道的导管和相关装置公开(公告)号：US08753366B2
公开(公告)日：2014-06-17
申请号：US12634850
申请日：2009-12-10
申请人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Philip Christopher Evard , Patrick Edward Macaulay , John Thomas Garibotto , Margaret W. Tumas , Alan Robert Selfridge
发明人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Philip Christopher Evard , Patrick Edward Macaulay , John Thomas Garibotto , Margaret W. Tumas , Alan Robert Selfridge
IPC分类号： A61B17/34
CPC分类号： A61B17/3439 , A61B8/12 , A61B8/445 , A61B8/4488 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12136 , A61B17/3207 , A61B17/3417 , A61B18/00 , A61B18/1477 , A61B18/1492 , A61B90/39 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/00504 , A61B2017/1107 , A61B2017/1139 , A61B2017/12127 , A61B2017/22067 , A61B2017/22068 , A61B2017/22069 , A61B2017/22072 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61B2018/1425 , A61B2090/0811 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61F2/2493 , A61F2002/30079 , A61F2210/009 , A61M25/0084 , A61M25/0141 , A61M25/0147 , A61M25/0155 , A61M29/00 , A61M29/02 , A61M2025/0076 , A61M2025/009 , A61M2025/1052
摘要： The inventions described in this patent application include i) a torqueable introducer sheath which is useable in conjunction with a transvascular passageway forming catheter to effect precise rotational control of the catheter; ii) an anchorable guide catheter which is useable in conjunction with an intravascular imaging catheter and a transvascular passageway-forming catheter to effect precise positioning and aiming of the passageway-forming catheter; iii) a passageway forming catheter having a torqueable proximal portion to facilitate precise rotational positioning of the distal portion of the catheter; iv) a deflectable-tipped passageway forming catheter, v) various markers and other apparatus useable in conjunction with any of the passageway-forming catheters to facilitate precise positioning and aiming of the catheter, and vi) an apparatus which may be formed within a catheter to prevent a member, apparatus of flow of material from being inadvertently advanced through a lumen of the catheter.
摘要翻译： 本专利申请中描述的发明包括：i）可扭转导引鞘，其可与形成导管的经血管通路结合使用以实现导管的精确旋转控制; ii）可锚定的导管，其可与血管内成像导管和经血管通路形成导管结合使用，以实现通道形成导管的精确定位和瞄准; iii）通道形成导管，其具有可扭转的近端部分，以便于导管的远端部分的精确的旋转定位; iv）可偏转尖端的通道形成导管，v）各种标记物和可与任何通道形成导管结合使用的其它装置，以便于导管的精确定位和瞄准，以及vi）可形成在导管内的装置 以防止材料流动的装置不经意地推进通过导管的内腔。
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公开(公告)号：US06302875B1
公开(公告)日：2001-10-16
申请号：US08837294
申请日：1997-04-11
申请人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Philip Christopher Evard , Patrick Edward Macaulay , John Thomas Garibotto , Margaret W. Tumas , Alan Robert Selfridge
发明人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Philip Christopher Evard , Patrick Edward Macaulay , John Thomas Garibotto , Margaret W. Tumas , Alan Robert Selfridge
IPC分类号： A61M3700
CPC分类号： A61B17/3439 , A61B8/12 , A61B8/445 , A61B8/4488 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12136 , A61B17/3207 , A61B17/3417 , A61B18/00 , A61B18/1477 , A61B18/1492 , A61B90/39 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/00504 , A61B2017/1107 , A61B2017/1139 , A61B2017/12127 , A61B2017/22067 , A61B2017/22068 , A61B2017/22069 , A61B2017/22072 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61B2018/1425 , A61B2090/0811 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61F2/2493 , A61F2002/30079 , A61F2210/009 , A61M25/0084 , A61M25/0141 , A61M25/0147 , A61M25/0155 , A61M29/00 , A61M29/02 , A61M2025/0076 , A61M2025/009 , A61M2025/1052
摘要： The inventions described in this patent application include i) a torqueable introducer sheath which is useable in conjunction with a transvascular passageway forming catheter to effect precise rotational control of the catheter; ii) an anchorable guide catheter which is useable in conjunction with an intravascular imaging catheter and a transvascular passageway-forming catheter to effect precise positioning and aiming of the passageway-forming catheter; iii) a passageway forming catheter having a torqueable proximal portion to facilitate precise rotational positioning of the distal portion of the catheter; iv) a deflectable-tipped passageway forming catheter, v) various markers and other apparatus useable in conjunction with any of the passageway-forming catheters to facilitate precise positioning and aiming of the catheter, and vi) an apparatus which may be formed within a catheter to prevent a member, apparatus of flow of material from being inadvertently advanced through a lumen of the catheter.
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3.发明申请Catheters and Related Devices for Forming Passageways Between Blood Vessels or Other Anatomical Structures 有权用于在血管或其他解剖结构之间形成通道的导管和相关装置公开(公告)号：US20100094259A1
公开(公告)日：2010-04-15
申请号：US12634850
申请日：2009-12-10
申请人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Philip Christopher Evard , Patrick Edward Macaulay , John Thomas Garibotto , Margaret W. Tumas , Alan Robert Selfridge
发明人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Philip Christopher Evard , Patrick Edward Macaulay , John Thomas Garibotto , Margaret W. Tumas , Alan Robert Selfridge
CPC分类号： A61B17/3439 , A61B8/12 , A61B8/445 , A61B8/4488 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12136 , A61B17/3207 , A61B17/3417 , A61B18/00 , A61B18/1477 , A61B18/1492 , A61B90/39 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/00504 , A61B2017/1107 , A61B2017/1139 , A61B2017/12127 , A61B2017/22067 , A61B2017/22068 , A61B2017/22069 , A61B2017/22072 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61B2018/1425 , A61B2090/0811 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61F2/2493 , A61F2002/30079 , A61F2210/009 , A61M25/0084 , A61M25/0141 , A61M25/0147 , A61M25/0155 , A61M29/00 , A61M29/02 , A61M2025/0076 , A61M2025/009 , A61M2025/1052
摘要： The inventions described in this patent application include i) a torqueable introducer sheath which is useable in conjunction with a transvascular passageway forming catheter to effect precise rotational control of the catheter; ii) an anchorable guide catheter which is useable in conjunction with an intravascular imaging catheter and a transvascular passageway-forming catheter to effect precise positioning and aiming of the passageway-forming catheter; iii) a passageway forming catheter having a torqueable proximal portion to facilitate precise rotational positioning of the distal portion of the catheter; iv) a deflectable-tipped passageway forming catheter, v) various markers and other apparatus useable in conjunction with any of the passageway-forming catheters to facilitate precise positioning and aiming of the catheter, and vi) an apparatus which may be formed within a catheter to prevent a member, apparatus of flow of material from being inadvertently advanced through a lumen of the catheter.
摘要翻译： 本专利申请中描述的发明包括：i）可扭转导引鞘，其可与形成导管的经血管通路结合使用以实现导管的精确旋转控制; ii）可锚定的导管，其可与血管内成像导管和经血管通路形成导管结合使用，以实现通道形成导管的精确定位和瞄准; iii）通道形成导管，其具有可扭转的近端部分，以便于导管的远端部分的精确的旋转定位; iv）可偏转尖端的通道形成导管，v）各种标记物和可与任何通道形成导管结合使用的其它装置，以便于导管的精确定位和瞄准，以及vi）可形成在导管内的装置 以防止材料流动的装置不经意地推进通过导管的内腔。
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4.发明授权Catheters and related devices for forming passageways between blood vessels or other anatomical structures 有权用于在血管或其他解剖结构之间形成通道的导管和相关装置公开(公告)号：US07648517B2
公开(公告)日：2010-01-19
申请号：US09912122
申请日：2001-07-24
申请人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Philip Christopher Evard , Patrick Edward Macauley , John Thomas Garibotto , Margaret W. Tumas , Alan Robert Selfridge
发明人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Philip Christopher Evard , Patrick Edward Macauley , John Thomas Garibotto , Margaret W. Tumas , Alan Robert Selfridge
CPC分类号： A61B17/3439 , A61B8/12 , A61B8/445 , A61B8/4488 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12136 , A61B17/3207 , A61B17/3417 , A61B18/00 , A61B18/1477 , A61B18/1492 , A61B90/39 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/00504 , A61B2017/1107 , A61B2017/1139 , A61B2017/12127 , A61B2017/22067 , A61B2017/22068 , A61B2017/22069 , A61B2017/22072 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61B2018/1425 , A61B2090/0811 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61F2/2493 , A61F2002/30079 , A61F2210/009 , A61M25/0084 , A61M25/0141 , A61M25/0147 , A61M25/0155 , A61M29/00 , A61M29/02 , A61M2025/0076 , A61M2025/009 , A61M2025/1052
摘要： The inventions described in this patent application include i) a torqueable introducer sheath which is useable in conjunction with a transvascular passageway forming catheter to effect precise rotational control of the catheter; ii) an anchorable guide catheter which is useable in conjunction with an intravascular imaging catheter and a transvascular passageway-forming catheter to effect precise positioning and aiming of the passageway-forming catheter; iii) a passageway forming catheter having a torqueable proximal portion to facilitate precise rotational positioning of the distal portion of the catheter; iv) a deflectable-tipped passageway forming catheter, v) various markers and other apparatus useable in conjunction with any of the passageway-forming catheters to facilitate precise positioning and aiming of the catheter, and vi) an apparatus which may be formed within a catheter to prevent a member, apparatus of flow of material from being inadvertently advanced through a lumen of the catheter.
摘要翻译： 本专利申请中描述的发明包括：i）可扭转导引鞘，其可与形成导管的经血管通路结合使用以实现导管的精确旋转控制; ii）可锚定的导管，其可与血管内成像导管和经血管通路形成导管结合使用，以实现通道形成导管的精确定位和瞄准; iii）通道形成导管，其具有可扭转的近端部分，以便于导管的远端部分的精确的旋转定位; iv）可偏转尖端的通道形成导管，v）各种标记物和可与任何通道形成导管结合使用的其它装置，以便于导管的精确定位和瞄准，以及vi）可形成在导管内的装置 以防止材料流动的装置不经意地推进通过导管的内腔。
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公开(公告)号：US07134438B2
公开(公告)日：2006-11-14
申请号：US10425543
申请日：2003-04-29
申请人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Philip Christopher Evard , Patrick Edward Macaulay , John Thomas Garibotto , Claude A. Vidal , Russell J. Redmond , Thomas Banks
发明人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Philip Christopher Evard , Patrick Edward Macaulay , John Thomas Garibotto , Claude A. Vidal , Russell J. Redmond , Thomas Banks
IPC分类号： A61B19/00
CPC分类号： A61B1/3137 , A61B17/00234 , A61B17/00491 , A61B17/0057 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12131 , A61B17/12136 , A61B17/320725 , A61B17/3417 , A61B17/3496 , A61B18/00 , A61B18/1445 , A61B18/1477 , A61B18/1492 , A61B18/24 , A61B90/361 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/00331 , A61B2017/00504 , A61B2017/00637 , A61B2017/00668 , A61B2017/0641 , A61B2017/1107 , A61B2017/1139 , A61B2017/12127 , A61B2017/22038 , A61B2017/22077 , A61B2017/22095 , A61B2017/306 , A61B2017/347 , A61B2017/3488 , A61B2018/00392 , A61B2018/00404 , A61B2018/00869 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61B2090/3958 , A61F2/07 , A61F2/2493 , A61F2/90 , A61F2/95 , A61F2002/30079 , A61F2002/8486 , A61F2210/009 , A61M2025/0076 , A61M2025/0096 , A61M2025/018 , A61M2025/1052
摘要： Methods, devices, and systems for a) revascularization and/or b) performing other medical procedures at vascular or non-vascular intracorporeal locations within a mammalian body. The methods generally comprise the formation of at least one extravascular passageway from a blood vessel to a vascular or non-vascular target location. In the revascularization methods the extravascular passageway is utilized for blood flow. In the medical procedure methods the extravascular passageway is utilized as a conduit for accessing or performing procedures at the vascular or non-vascular target location. Also disclosed are catheter devices and systems which are useable to form the extravascular passageways of the invention, as well as apparatus for modifying, maintaining and/or closing such extravascular passageways.
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6.发明授权Methods and apparatus for bypassing arterial obstructions and/or performing other transvascular procedures 失效旁路动脉阻塞和/或执行其他血管内手术的方法和装置公开(公告)号：US07059330B1
公开(公告)日：2006-06-13
申请号：US09708923
申请日：2000-11-08
申请人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Philip Christopher Evard , Patrick Edward Macaulay , John Thomas Garibotto , Claude A. Vidal , Russell J. Redmond , Thomas Banks
发明人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Philip Christopher Evard , Patrick Edward Macaulay , John Thomas Garibotto , Claude A. Vidal , Russell J. Redmond , Thomas Banks
CPC分类号： A61B1/3137 , A61B17/00234 , A61B17/00491 , A61B17/0057 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12131 , A61B17/12136 , A61B17/320725 , A61B17/3417 , A61B17/3496 , A61B18/00 , A61B18/1445 , A61B18/1477 , A61B18/1492 , A61B18/24 , A61B90/361 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/00331 , A61B2017/00504 , A61B2017/00637 , A61B2017/00668 , A61B2017/0641 , A61B2017/1107 , A61B2017/1139 , A61B2017/12127 , A61B2017/22038 , A61B2017/22077 , A61B2017/22095 , A61B2017/306 , A61B2017/347 , A61B2017/3488 , A61B2018/00392 , A61B2018/00404 , A61B2018/00869 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61B2090/3958 , A61F2/07 , A61F2/2493 , A61F2/90 , A61F2/95 , A61F2002/30079 , A61F2002/8486 , A61F2210/009 , A61M2025/0076 , A61M2025/0096 , A61M2025/018 , A61M2025/1052
摘要： Methods, devices, and systems for a) revascularization and/or b) performing other medical procedures at vascular or non-vascular intracorporeal locations within a mammalian body. The methods generally comprise the formation of at least one extravascular passageway from a blood vessel to a vascular or non-vascular target location. In the revascularization methods the extravascular passageway is utilized for blood flow. In the medical procedure methods the extravascular passageway is utilized as a conduit for accessing or performing procedures at the vascular or non-vascular target location. Also disclosed are catheter devices and systems which are useable to form the extravascular passageways of the invention, as well as apparatus for modifying, maintaining and/or closing such extravascular passageways.
摘要翻译： 方法，装置和系统，用于a）血管重建和/或b）在哺乳动物体内的血管或非血管体内位置执行其他医学程序。 所述方法通常包括从血管到血管或非血管目标位置形成至少一个血管内通道。 在血运重建方法中，血管外通路用于血流。 在医疗程序方法中，血管外通路被用作在血管或非血管目标位置处进入或执行手术的导管。 还公开了可用于形成本发明的血管外通道的导管装置和系统，以及用于修改，维持和/或关闭这种血管外通道的装置。
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公开(公告)号：US06655386B1
公开(公告)日：2003-12-02
申请号：US09639963
申请日：2000-08-16
申请人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Philip Christopher Evard , Patrick Edward Macaulay , John Thomas Garibotto , Claude A. Vidal , Russell J. Redmond , Thomas Banks
发明人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Philip Christopher Evard , Patrick Edward Macaulay , John Thomas Garibotto , Claude A. Vidal , Russell J. Redmond , Thomas Banks
IPC分类号： A61B1900
CPC分类号： A61B1/3137 , A61B17/00234 , A61B17/00491 , A61B17/0057 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12131 , A61B17/12136 , A61B17/320725 , A61B17/3417 , A61B17/3496 , A61B18/00 , A61B18/1445 , A61B18/1477 , A61B18/1492 , A61B18/24 , A61B90/361 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/00331 , A61B2017/00504 , A61B2017/00637 , A61B2017/00668 , A61B2017/0641 , A61B2017/1107 , A61B2017/1139 , A61B2017/12127 , A61B2017/22038 , A61B2017/22077 , A61B2017/22095 , A61B2017/306 , A61B2017/347 , A61B2017/3488 , A61B2018/00392 , A61B2018/00404 , A61B2018/00869 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61B2090/3958 , A61F2/07 , A61F2/2493 , A61F2/90 , A61F2/95 , A61F2002/30079 , A61F2002/8486 , A61F2210/009 , A61M2025/0076 , A61M2025/0096 , A61M2025/018 , A61M2025/1052
摘要： Methods, devices, and systems for a) revascularization and/or b) performing other medical procedures at vascular or non-vascular intracorporeal locations within a mammalian body. The methods generally comprise the formation of at least one extravascular passageway from a blood vessel to a vascular or non-vascular target location. In the revascularization methods the extravascular passageway is utilized for blood flow. In the medical procedure methods the extravascular passageway is utilized as a conduit for accessing or performing procedures at the vascular or non-vascular target location. Also disclosed are catheter devices and systems which are useable to form the extravascular passageways of the invention, as well as apparatus for modifying, maintaining and/or closing such extravascular passageways.
摘要翻译： 方法，装置和系统，用于a）血管重建和/或b）在哺乳动物体内的血管或非血管体内位置执行其他医学程序。 所述方法通常包括从血管到血管或非血管目标位置形成至少一个血管内通道。 在血运重建方法中，血管外通路用于血流。 在医疗程序方法中，血管外通路被用作在血管或非血管目标位置处进入或执行手术的导管。 还公开了可用于形成本发明的血管外通道的导管装置和系统，以及用于修改，维持和/或关闭这种血管外通道的装置。
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8.发明授权Methods and apparatus for bypassing arterial obstructions and/or performing other transvascular procedures 失效旁路动脉阻塞和/或执行其他血管内手术的方法和装置公开(公告)号：US06190353B1
公开(公告)日：2001-02-20
申请号：US08730327
申请日：1996-10-11
申请人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Philip Christopher Evard , Patrick Edward Macaulay , John Thomas Garibotto , Claude A. Vidal , Russell J. Redmond , Thomas Banks
发明人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Philip Christopher Evard , Patrick Edward Macaulay , John Thomas Garibotto , Claude A. Vidal , Russell J. Redmond , Thomas Banks
IPC分类号： A61M3700
CPC分类号： A61B1/3137 , A61B17/00234 , A61B17/00491 , A61B17/0057 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12131 , A61B17/12136 , A61B17/320725 , A61B17/3417 , A61B17/3496 , A61B18/00 , A61B18/1445 , A61B18/1477 , A61B18/1492 , A61B18/24 , A61B90/361 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/00331 , A61B2017/00504 , A61B2017/00637 , A61B2017/00668 , A61B2017/0641 , A61B2017/1107 , A61B2017/1139 , A61B2017/12127 , A61B2017/22038 , A61B2017/22077 , A61B2017/22095 , A61B2017/306 , A61B2017/347 , A61B2017/3488 , A61B2018/00392 , A61B2018/00404 , A61B2018/00869 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61B2090/3958 , A61F2/07 , A61F2/2493 , A61F2/90 , A61F2/95 , A61F2002/30079 , A61F2002/8486 , A61F2210/009 , A61M2025/0076 , A61M2025/0096 , A61M2025/018 , A61M2025/1052
摘要： Methods, devices, and systems for a) revascularization and/or b) performing other medical procedures at vascular or non-vascular intracorporeal locations within a mammalian body. The methods generally comprise the formation of at least one extravascular passageway from a blood vessel to a vascular or non-vascular target location. In the revascularization methods the extravascular passageway is utilized for blood flow. In the medical procedure methods the extravascular passageway is utilized as a conduit for accessing or performing procedures at the vascular or non-vascular target location. Also disclosed are catheter devices and systems which are useable to form the extravascular passageways of the invention, as well as apparatus for modifying, maintaining and/or closing such extravascular passageways.
摘要翻译： 方法，装置和系统，用于a）血管重建和/或b）在哺乳动物体内的血管或非血管体内位置执行其他医学程序。 所述方法通常包括从血管到血管或非血管目标位置形成至少一个血管内通道。 在血运重建方法中，血管外通路用于血流。 在医疗程序方法中，血管外通路被用作在血管或非血管目标位置处进入或执行手术的导管。 还公开了可用于形成本发明的血管外通道的导管装置和系统，以及用于修改，维持和/或关闭这种血管外通道的装置。
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