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公开(公告)号:US07923439B2
公开(公告)日:2011-04-12
申请号:US12573232
申请日:2009-10-05
申请人: Joshua Stopek , Ahmad Hadba
发明人: Joshua Stopek , Ahmad Hadba
CPC分类号: A61K31/74 , A61L17/145 , A61L27/18 , A61L27/34 , C08F220/60 , C08F224/00 , C08F230/02
摘要: The present disclosure provides compositions including a first component including at least one phospholipid possessing at least one vinyl group, a second component including a furanone possessing vinyl and/or acrylate groups, and a third component including a hydroxamate. Compositions, medical devices, and coatings including copolymers and blends of the foregoing components are also provided.
摘要翻译: 本公开提供了包含第一组分的组合物,其包含至少一种具有至少一个乙烯基的磷脂,第二组分包括具有乙烯基和/或丙烯酸酯基团的呋喃酮,以及包含异羟肟酸酯的第三组分。 还提供了组合物,医疗装置和包括前述组分的共聚物和共混物的涂层。
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公开(公告)号:US20100093846A1
公开(公告)日:2010-04-15
申请号:US12573232
申请日:2009-10-05
申请人: Joshua Stopek , Ahmad Hadba
发明人: Joshua Stopek , Ahmad Hadba
CPC分类号: A61K31/74 , A61L17/145 , A61L27/18 , A61L27/34 , C08F220/60 , C08F224/00 , C08F230/02
摘要: The present disclosure provides compositions including a first component including at least one phospholipid possessing at least one vinyl group, a second component including a furanone possessing vinyl and/or acrylate groups, and a third component including a hydroxamate. Compositions, medical devices, and coatings including copolymers and blends of the foregoing components are also provided.
摘要翻译: 本公开提供了包含第一组分的组合物,其包含至少一种具有至少一个乙烯基的磷脂,第二组分包括具有乙烯基和/或丙烯酸酯基团的呋喃酮,以及包含异羟肟酸酯的第三组分。 还提供了组合物,医疗装置和包括前述组分的共聚物和共混物的涂层。
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公开(公告)号:US20080064839A1
公开(公告)日:2008-03-13
申请号:US11660566
申请日:2005-08-16
申请人: Ahmad Hadba , Brian Cuevas , Frank Schiretz , Joshua Stopek
发明人: Ahmad Hadba , Brian Cuevas , Frank Schiretz , Joshua Stopek
CPC分类号: A61L24/043 , A61B17/06166 , A61B17/064 , A61B2017/00898 , A61L17/10 , A61L31/041 , A61L2400/04 , C08F220/06 , C08F220/38 , C08F220/58 , C08L33/14 , Y10T428/2964 , Y10T428/2967 , Y10T428/2969 , C08L33/04 , C08L2666/02
摘要: The present disclosure relates to compositions comprising a copolymer that includes a first monomer and a second monomer that is different from the first monomer, wherein both the first and second monomer are selected from the group consisting of 3-sulfopropyl acrylate potassium salt, sodium acrylate, N-(tris(hydroxyl methyl)methyl)acrylamide, and 2-acrylamideo-2-methyl-1-propane sulfonic acid. The present disclosure further relates to methods for preparing the copolymer compositions and shaped articles comprising the copolymers.
摘要翻译: 本公开涉及包含共聚物的组合物,所述共聚物包括不同于第一单体的第一单体和第二单体,其中第一和第二单体都选自丙烯酸3-磺丙酯钾盐,丙烯酸钠, N-(三(羟基甲基)甲基)丙烯酰胺,和2-丙烯酸异丙基-2-甲基-1-丙磺酸。 本公开还涉及制备包含共聚物的共聚物组合物和成型制品的方法。
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公开(公告)号:US20100092533A1
公开(公告)日:2010-04-15
申请号:US12572358
申请日:2009-10-02
申请人: Joshua Stopek , Ahmad Hadba
发明人: Joshua Stopek , Ahmad Hadba
IPC分类号: A61K9/00 , A61K31/765 , A61K31/74 , A61P41/00
CPC分类号: C08G18/40 , A61L24/0042 , A61L24/04 , A61L27/14 , A61L27/58
摘要: Bioabsorbable macromer compositions are provided including a polymeric component possessing a hydroxamate segment and a polymer segment. The polymeric component can be used by itself, or in some embodiments, combined with a second component, to form a macromer composition of the present disclosure. The resulting bioabsorbable macromer composition can be employed as an adhesive or sealant for medical/surgical uses.
摘要翻译: 提供了生物可吸收的大分子单体组合物,包括含有异羟肟酸盐链段和聚合物链段的聚合物组分。 聚合物组分可以单独使用,或在一些实施方案中与第二组分组合使用,以形成本发明的大分子单体组合物。 所得到的生物可吸收大分子单体组合物可用作医疗/外科用途的粘合剂或密封剂。
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公开(公告)号:US20070202075A1
公开(公告)日:2007-08-30
申请号:US11712333
申请日:2007-02-28
申请人: Ahmad Hadba , Joshua Stopek
发明人: Ahmad Hadba , Joshua Stopek
CPC分类号: C09J189/00 , A61L24/043 , A61L24/108 , C08L89/00
摘要: Compositions provided by mixing a biotin-containing component and an avidin-containing component are useful as an adhesive or sealant for medical/surgical uses.
摘要翻译: 通过混合含有生物素的组分和含抗生物素蛋白的组分提供的组合物可用作医疗/外科用途的粘合剂或密封剂。
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公开(公告)号:US20070135606A1
公开(公告)日:2007-06-14
申请号:US11636227
申请日:2006-12-08
申请人: Nadya Belcheva , Ahmad Hadba
发明人: Nadya Belcheva , Ahmad Hadba
IPC分类号: C08G18/00
CPC分类号: C08G18/721 , C08G18/10 , C08G18/283 , C08G18/3225 , C08G18/5021 , C08G2190/00 , C08G2230/00 , C09J175/08
摘要: Biocompatible compositions are provided including a first polymer component including an isocyanate-functional polyalkylene oxide combined with at least one multi-isocyanate functional polyether-polyurethane, and a second component including at least one diamine.
摘要翻译: 提供生物相容性组合物,其包括第一聚合物组分,其包含与至少一种多异氰酸酯官能聚醚 - 聚氨酯组合的异氰酸酯官能的聚环氧烷,和包含至少一种二胺的第二组分。
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公开(公告)号:US20070135605A1
公开(公告)日:2007-06-14
申请号:US11636159
申请日:2006-12-08
申请人: Ahmad Hadba , Nadya Belcheva
发明人: Ahmad Hadba , Nadya Belcheva
IPC分类号: C08G18/00
CPC分类号: C09J177/00 , A61B17/0057 , A61L24/04 , C08G18/10 , C08G18/283 , C08G18/3203 , C08G18/3206 , C08G18/3278 , C08G18/3281 , C08G18/4277 , C08G18/4615 , C08G18/4887 , C08G18/73 , C08G2190/00 , C08G2230/00 , C08L77/04 , C09J175/04
摘要: Biocompatible macromer compositions are provided including an isocyanate-functional polyalkylene oxide combined with at least one multi-functional isocyanate as a first component, and a multi-amino functional compound possessing multiple primary amines as a second component. The isocyanate-functional polyalkylene oxide has pendant polyalkylene oxide groups. The resulting biocompatible macromer composition can be employed as an adhesive or sealant for medical/surgical uses.
摘要翻译: 提供生物相容性大分子单体组合物,其包括与作为第一组分的至少一种多官能异氰酸酯组合的异氰酸酯官能的聚环氧烷烃,以及具有多个伯胺作为第二组分的多氨基官能化合物。 异氰酸酯官能的聚环氧烷具有侧链聚环氧烷基团。 所得的生物相容性大分子单体组合物可用作医疗/外科用途的粘合剂或密封剂。
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公开(公告)号:US20070128152A1
公开(公告)日:2007-06-07
申请号:US11635294
申请日:2006-12-06
申请人: Ahmad Hadba , Nadya Belcheva
发明人: Ahmad Hadba , Nadya Belcheva
IPC分类号: A61K31/785 , C08F20/00
CPC分类号: A61L24/046 , A61L15/26 , A61L26/0019 , C08G18/10 , C08G18/4812 , C08G18/6212 , C08G18/6681 , C08G2190/00 , C09J175/04 , C08L75/04 , C08G18/42 , C08G18/32
摘要: The disclosure relates to compositions for medical/surgical synthetic adhesives and sealants. Adhesive compositions include a functionalized triol and functionalized diol, while sealant compositions further include a multifunctionalized polyol and at least one amine cross linker.
摘要翻译: 本公开涉及用于医疗/外科合成粘合剂和密封剂的组合物。 粘合剂组合物包括官能化三醇和官能化二醇,而密封剂组合物还包括多官能化多元醇和至少一种胺交联剂。
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公开(公告)号:US20060291981A1
公开(公告)日:2006-12-28
申请号:US11444761
申请日:2006-06-01
申请人: Frank Viola , Ken Blier , Ahmad Hadba , Russell Heinrich
发明人: Frank Viola , Ken Blier , Ahmad Hadba , Russell Heinrich
IPC分类号: F16B15/00
CPC分类号: F16B15/0015 , A61B17/0644 , A61B17/07292
摘要: A staple having an expandable backspan and a pair of spaced legs is described. The expandable backspan is configured to expand or deform to accommodate tissues of varying thicknesses. In one embodiment, the backspan is non-linear and defines a recess. In another embodiment, the backspan includes a deformable pad or spacer. The amount of deformation of the backspan is proportional to the thickness of the tissue, i.e., the greater the thickness of tissue, the greater the deformation of the backspan.
摘要翻译: 描述了具有可扩展的后跨和一对间隔的腿的钉。 可扩展的后桥被构造成膨胀或变形以适应不同厚度的组织。 在一个实施例中,后跨是非线性的并且限定了凹部。 在另一个实施例中,后跨跨度包括可变形垫或间隔件。 背板的变形量与组织的厚度成比例,即组织的厚度越大,后跨的变形越大。
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公开(公告)号:US20070148128A1
公开(公告)日:2007-06-28
申请号:US11635344
申请日:2006-12-06
申请人: John Kennedy , Mark Roby , Ahmad Hadba
发明人: John Kennedy , Mark Roby , Ahmad Hadba
CPC分类号: C08L71/02 , A61K31/74 , A61L24/0042 , A61L24/043 , C08G65/329 , C08G65/332 , C08L79/00 , C08L79/08 , C08L2666/14
摘要: A synthetic composition is provided which includes an acid-functional polymer having at least one pendant acid group, an amine-functional polymer having at least one pendant amine group, and a coupling agent. The synthetic composition can be used in human and animal medical applications as an adhesive or sealant.
摘要翻译: 提供了一种合成组合物,其包括具有至少一个侧链酸基的酸官能聚合物,具有至少一个侧基胺基的胺官能聚合物和偶联剂。 合成组合物可用作人和动物医疗应用中的粘合剂或密封剂。
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