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公开(公告)号：US20140378559A1
公开(公告)日：2014-12-25
申请号：US14368990
申请日：2011-12-19
申请人： Jun Liu , Sanglu Qin , Xiangrui Wang , Xia Cao , Ryan Hulse , Yunjie Xing , Zhongxi Huang , Zhili Lu
发明人： Jun Liu , Sanglu Qin , Xiangrui Wang , Xia Cao , Ryan Hulse , Yunjie Xing , Zhongxi Huang , Zhili Lu
CPC分类号： B01F17/0035 , C08J9/141 , C08J9/142 , C08J9/146 , C08J9/149 , C08J2201/022 , C08J2203/12 , C08J2203/14 , C08J2203/142 , C08J2203/202 , C08J2205/05 , C08J2205/052 , C08J2205/06 , C08J2205/10 , C08J2375/04 , C09K3/30
摘要： A composition comprising HFC-245fa, cyclopentane, and a third solvent component, wherein the composition is in a homogenous one-phase solution state at temperatures less than the boiling temperature of the composition, and uses thereof, including as blowing agents.
摘要翻译： 包含HFC-245fa，环戊烷和第三溶剂组分的组合物，其中所述组合物在低于所述组合物的沸点温度的温度下为均匀的单相溶液状态，以及其用途，包括作为发泡剂。
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公开(公告)号：USD994161S1
公开(公告)日：2023-08-01
申请号：US29815444
申请日：2021-11-14
申请人： Xia Cao
设计人： Xia Cao
摘要： FIG. 1 is a perspective view of a light string showing my new design;
FIG. 2 is another perspective view thereof;
FIG. 3 is a front elevational view thereof;
FIG. 4 is a rear elevational view thereof;
FIG. 5 is a left side elevational view thereof;
FIG. 6 is a right side elevational view thereof;
FIG. 7 is a top plan view thereof; and,
FIG. 8 is a bottom plan view thereof.
The light string is shown with a symbolic break in its length and the appearance of any portion of the light string between the break lines form no part of the claimed design. The broken lines in the drawings depict portions of the light string that form no part of the claimed design.-
公开(公告)号：US09193837B1
公开(公告)日：2015-11-24
申请号：US13430491
申请日：2012-03-26
申请人： L. James Lee , Gang Zhou , Xia Cao
发明人： L. James Lee , Gang Zhou , Xia Cao
摘要： A composite material having polymeric resin with disperse phases of reinforcing fibers and nanoparticle materials and its manufacture is disclosed herein. The nanoparticles may be bound together and added to the polymeric resin as microscale aggregations, and then unbound to create a disperse phase of nanoparticles in the resin. In other embodiments, the nanoparticles may be bound to a substrate, such as long fibers, and added to a polymeric resin. The nanoparticles are then unbound from the substrate and dispersed throughout the polymeric resin. The polymeric resin may have multiple components where one component may control the dispersion of the nanoparticles.
摘要翻译： 具有聚合物树脂的复合材料，其具有分散相的增强纤维和纳米颗粒材料及其制造。 纳米颗粒可以结合在一起，并以微量聚集体形式加入到聚合物树脂中，然后未结合以在树脂中产生纳米颗粒的分散相。 在其他实施方案中，纳米颗粒可以结合到基底，例如长纤维上，并加入到聚合物树脂中。 然后，纳米颗粒从基材未结合并分散在整个聚合物树脂中。 聚合物树脂可以具有多种组分，其中一种组分可以控制纳米颗粒的分散。
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公开(公告)号：US08931229B2
公开(公告)日：2015-01-13
申请号：US13642292
申请日：2011-04-05
CPC分类号： E04B1/665 , C09J7/38 , C09J7/401 , C09J2205/114 , C09J2401/005 , C09J2425/005 , C09J2429/005 , C09J2431/005 , C09J2433/005 , C09J2471/005 , C09J2479/025 , C09J2483/005 , E01D19/083 , E04B2001/7691 , E04G21/00 , Y10T428/24355 , Y10T428/259 , Y10T428/273 , Y10T428/2835
摘要： Disclosed is a waterproofing membrane that comprises a carrier sheet, a pressure sensitive adhesive layer on one surface of the carrier sheet, and a protective coating layer on the adhesive layer. The protective coating layer comprises a highly reflective protective coating layer operative to bond to concrete cast against it, particularly one that is produced from an aqueous coating comprising an acrylic emulsion, a filler, and a white pigment. The pigment volume concentration of the filler plus white pigment is greater than or equal to 55% by volume. The protective coating layer protects the membrane against weather exposure, tolerates foot traffic and strongly adheres to concrete cast against it. Also disclosed is a waterproofing membrane comprising a carrier sheet, a pressure sensitive adhesive layer, a protective coating layer, and a highly releasable bonding layer. The preferred highly releasable bonding layer comprises nanoscale silica and a binder.
摘要翻译： 公开了一种防水膜，其包括载体片，载体片的一个表面上的压敏粘合剂层和粘合剂层上的保护涂层。 保护性涂层包括高反射性保护涂层，其可操作地结合到其上浇注的混凝土，特别是由包含丙烯酸乳液，填料和白色颜料的水性涂料制备的涂层。 填料加白色颜料的颜料体积浓度大于或等于55体积％。 保护涂层保护膜免受天气暴露，容忍脚部流动，并强烈地粘附在其上。 还公开了一种防水膜，其包括载体片，压敏粘合剂层，保护涂层和高度可剥离的粘合层。 优选的高度可释放的粘合层包括纳米二氧化硅和粘合剂。
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公开(公告)号：US20070199265A1
公开(公告)日：2007-08-30
申请号：US11468544
申请日：2006-08-30
申请人： Brian Iske , Jyoti Seth , Xia Cao , Sonya Santos , Enzo Orellana
发明人： Brian Iske , Jyoti Seth , Xia Cao , Sonya Santos , Enzo Orellana
IPC分类号： E04B1/70
CPC分类号： E21D11/381 , E02D31/02
摘要： The present invention relates to a multi-layer fluid delivery device for post-installation in-situ barrier creation. The device provides a medium for post-installation injection of remedial substances such as waterproofing polymeric resins or cementitious materials, insecticides, mold preventatives, rust retardants and the like. The device comprises a first layer and a second layer, with optionally an intermediate layer therebetween, and a plurality of tubes extending outwardly from the first layer. The first layer is preferably semi-permeable; the second layer is non-permeable; the optional intermediate layer is a void-inducing layer. The multi-layered device is attached to a structural substrate and a construction material such as concrete or shotcrete is applied against its surface (and around the plurality of tubes). Thereafter, a free flowing active substance can be injected through the tubes to fill the air space in the multi-layered device.
摘要翻译： 本发明涉及一种用于后置安装场所屏障创造的多层流体输送装置。 该装置提供用于后处理注射补救物质的介质，例如防水聚合物树脂或水泥质材料，杀虫剂，防霉剂，防锈剂等。 该装置包括第一层和第二层，其间可选地具有中间层，以及从第一层向外延伸的多个管。 第一层优选是半渗透的; 第二层是不可渗透的; 可选的中间层是空隙诱导层。 多层装置附接到结构基底，并且施加材料如混凝土或喷射混凝土施加到其表面（并且围绕多个管）。 此后，可以通过管子注入自由流动的活性物质以填充多层装置中的空气空间。
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公开(公告)号：US08931228B2
公开(公告)日：2015-01-13
申请号：US13642281
申请日：2011-04-06
CPC分类号： C09J7/0225 , C09J7/381 , C09J7/40 , E01D19/083 , E04B1/665 , E04B2001/7691 , Y10T428/24355 , Y10T428/259 , Y10T428/273 , Y10T428/2835
摘要： Disclosed is a waterproofing membrane that comprises a carrier sheet, a pressure sensitive adhesive layer on one surface of the carrier sheet, and a protective coating layer on the adhesive layer. The protective coating layer is highly reflective (optionally textured) and operative to bond to concrete cast against it. Preferably, the protective coating layer comprises cement, polymer, and white pigment, and may optionally or additionally include a filler, a UV absorber and an antioxidant. The protective coating layer protects the membrane against weather exposure, tolerates foot traffic and strongly adheres to concrete cast against it. Also disclosed is a waterproofing membrane comprising a carrier sheet, a pressure sensitive adhesive layer, a protective coating layer (as described above), and a highly releasable bonding layer.
摘要翻译： 公开了一种防水膜，其包括载体片，载体片的一个表面上的压敏粘合剂层和粘合剂层上的保护涂层。 保护性涂层是高反射性（任意纹理化的），并且可操作地粘结到与之相反的混凝土上。 优选地，保护性涂层包括水泥，聚合物和白色颜料，并且可以任选地或另外包括填料，UV吸收剂和抗氧化剂。 保护涂层保护膜免受天气暴露，容忍脚部流动，并强烈地粘附在其上。 还公开了一种防水膜，其包括载体片，压敏粘合剂层，保护涂层（如上所述）和高度可剥离的粘合层。
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7.发明申请公开(公告)号：US20110250269A1
公开(公告)日：2011-10-13
申请号：US13126183
申请日：2009-11-23
申请人： Ximing Xu , Jiangnan Yu , Yuan Zhu , Xia Cao
发明人： Ximing Xu , Jiangnan Yu , Yuan Zhu , Xia Cao
IPC分类号： A61K9/52 , A61K9/26 , B29B9/12 , A61K31/7048 , A61K31/4422 , A61K9/00 , A61K36/28
CPC分类号： A61K9/2054 , A61K9/143 , A61K9/146 , A61K9/2077 , A61K31/357 , A61K31/4422 , A61K31/7048
摘要： A high-efficacy, long-acting, slow-release formulation of the poorly soluble drug, comprising solid dispersion of the poorly soluble drug, silica nanoparticles loaded with the poorly soluble drug, matrix material, and release enhancer, wherein the mass ratio of these components is solid dispersion of the poorly soluble drug: silica nanoparticles loaded with the poorly soluble drug: matrix material: release enhancer=1: 0.5˜1.25: 0.1˜0.3: 0.1˜0.3; the said solid dispersion of the poorly soluble drug contains povidone K30, soybean lecithin, and acrylic resin IV, wherein the mass ratio of the drug and the accessory materials is poorly soluble drug: povidone K30: soybean lecithin: acrylic resin IV=1: 1-3: 0.3˜0.8: 0.2˜0.5. Compared with the existing formulations, the in vivo half life of the high-efficacy, long-acting formulation of the poorly soluble drug disclosed in this invention is 2.3˜14.8 times longer while the mean residence time (MRT) of which is 7.94˜4.52 times longer; when tested in vivo in Beagle dogs, this new formulation of the poorly soluble drug presents a smoother concentration-time curve and reaches a continuous release for 72 hours. This invention discloses its preparation method.
摘要翻译： 难溶性药物的高效，长效，缓释制剂，包括难溶性药物的固体分散体，负载有难溶性药物的二氧化硅纳米粒子，基质材料和释放增强剂，其中这些 组分是难溶性药物的固体分散体：载有难溶性药物的二氧化硅纳米粒子：基体材料：释放增强剂= 1:0.5〜1.25:0.1〜0.3:0.1〜0.3; 所述难溶性药物的固体分散体含有聚维酮K30，大豆卵磷脂和丙烯酸树脂IV，其中药物和辅助材料的质量比是难溶性药物：聚维酮K30：大豆卵磷脂：丙烯酸树脂IV = 1：1 -3：0.3〜0.8：0.2〜0.5。 与现有制剂相比，本发明公开的难溶性药物的高效长效制剂的体内半衰期为2.3〜14.8倍，平均停留时间（MRT）为7.94〜4.52 时间更长 当在Beagle犬体内进行体内测试时，这种新的低溶解性药物的制剂呈现出更平滑的浓度 - 时间曲线，达到连续释放72小时。 本发明公开了其制备方法。
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公开(公告)号：US20090282762A1
公开(公告)日：2009-11-19
申请号：US12477265
申请日：2009-06-03
申请人： Brian J. Iske , Jyoti Seth , Xia Cao , Sonya M. Santos , Enzo J. Orellana
发明人： Brian J. Iske , Jyoti Seth , Xia Cao , Sonya M. Santos , Enzo J. Orellana
CPC分类号： E21D11/381 , E02D31/02
摘要： The present invention relates to a multi-layer fluid delivery device for post-installation in-situ barrier creation. The device provides a medium for post-installation injection of remedial substances such as waterproofing polymeric resins or cementitious materials, insecticides, mold preventatives, rust retardants and the like. The device comprises a first layer and a second layer, with optionally an intermediate layer therebetween, and a plurality of tubes extending outwardly from the first layer. The first layer is preferably semi-permeable; the second layer is non-permeable; the optional intermediate layer is a void-inducing layer. The multi-layered device is attached to a structural substrate and a construction material such as concrete or shotcrete is applied against its surface (and around the plurality of tubes). Thereafter, a free flowing active substance can be injected through the tubes to fill the air space in the multi-layered device.
摘要翻译： 本发明涉及一种用于后置安装场所屏障创造的多层流体输送装置。 该装置提供用于后处理注射补救物质的介质，例如防水聚合物树脂或水泥质材料，杀虫剂，防霉剂，防锈剂等。 该装置包括第一层和第二层，其间可选地具有中间层，以及从第一层向外延伸的多个管。 第一层优选是半渗透的; 第二层是不可渗透的; 可选的中间层是空隙诱导层。 多层装置附接到结构基底，并且施加材料如混凝土或喷射混凝土施加到其表面（并且围绕多个管）。 此后，可以通过管子注入自由流动的活性物质以填充多层装置中的空气空间。
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9.发明授权公开(公告)号：US09283190B2
公开(公告)日：2016-03-15
申请号：US13126183
申请日：2009-11-23
申请人： Ximing Xu , Jiangnan Yu , Yuan Zhu , Xia Cao
发明人： Ximing Xu , Jiangnan Yu , Yuan Zhu , Xia Cao
IPC分类号： A61K9/20 , A61K31/357 , A61K31/4422 , A61K31/7048 , A61K9/14
CPC分类号： A61K9/2054 , A61K9/143 , A61K9/146 , A61K9/2077 , A61K31/357 , A61K31/4422 , A61K31/7048
摘要： A high-efficacy, long-acting, slow-release formulation of the poorly soluble drug, comprising solid dispersion of the poorly soluble drug, silica nanoparticles loaded with the poorly soluble drug, matrix material, and release enhancer, wherein the mass ratio of these components is solid dispersion of the poorly soluble drug: silica nanoparticles loaded with the poorly soluble drug: matrix material: release enhancer=1: 0.5˜1.25: 0.1˜0.3: 0.1˜0.3; the said solid dispersion of the poorly soluble drug contains povidone K30, soybean lecithin, and acrylic resin IV, wherein the mass ratio of the drug and the accessory materials is poorly soluble drug: povidone K30: soybean lecithin: acrylic resin IV=1: 1˜3: 0.3˜0.8: 0.2˜0.5. Compared with the existing formulations, the in vivo half life of the high-efficacy, long-acting formulation of the poorly soluble drug disclosed in this invention is 2.3˜14.8 times longer while the mean residence time (MRT) of which is 7.94˜4.52 times longer; when tested in vivo in Beagle dogs, this new formulation of the poorly soluble drug presents a smoother concentration-time curve and reaches a continuous release for 72 hours. This invention discloses its preparation method.
摘要翻译： 难溶性药物的高效，长效，缓释制剂，包括难溶性药物的固体分散体，负载有难溶性药物的二氧化硅纳米粒子，基质材料和释放增强剂，其中这些 组分是难溶性药物的固体分散体：载有难溶性药物的二氧化硅纳米粒子：基体材料：释放增强剂= 1:0.5〜1.25:0.1〜0.3:0.1〜0.3; 所述难溶性药物的固体分散体含有聚维酮K30，大豆卵磷脂和丙烯酸树脂IV，其中药物和辅助材料的质量比是难溶性药物：聚维酮K30：大豆卵磷脂：丙烯酸树脂IV = 1：1 〜3：0.3〜0.8：0.2〜0.5。 与现有制剂相比，本发明公开的难溶性药物的高效长效制剂的体内半衰期为2.3〜14.8倍，平均停留时间（MRT）为7.94〜4.52 时间更长 当在Beagle犬体内进行体内测试时，这种新的低溶解性药物的制剂呈现出更平滑的浓度 - 时间曲线，达到连续释放72小时。 本发明公开了其制备方法。
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10.发明授权Formulation of silymarin with high efficacy and prolonged action and the preparation method thereof 有权具有高效和长效作用的水飞蓟素的制备及其制备方法公开(公告)号：US08962017B2
公开(公告)日：2015-02-24
申请号：US13126071
申请日：2009-11-23
申请人： Ximing Xu , Jiangnan Yu , Shanshan Tong , Yuan Zhu , Xia Cao
发明人： Ximing Xu , Jiangnan Yu , Shanshan Tong , Yuan Zhu , Xia Cao
IPC分类号： A61K31/353 , A61P1/00 , A61P9/00 , A61P7/02 , B29B9/12 , B82Y5/00 , A61K31/357 , A61K9/14 , A61K9/51 , A61K47/02 , A61K47/24 , A61K47/30 , A61K47/32
CPC分类号： A61K31/357 , A61K9/146 , A61K9/5115 , A61K31/353 , A61K47/02 , A61K47/24 , A61K47/30 , A61K47/32 , Y10S977/773 , Y10S977/888 , Y10S977/906
摘要： A high-efficacy, long-acting formulation of silymarin, comprising silymarin solid dispersion, silymarin-loaded silica nanoparticles, slow-release matrix material and release enhancer, wherein the mass ratio of these components is silymarin solid dispersion:silymarin-loaded silica nanoparticles:slow-release matrix material:release enhancer=1:0.5˜1.25:0.1˜0.3:0.1˜0.3; the drug loading rate of the said silymarin-loaded silica nanoparticles is 51.95%-52.87%; the said silymarin solid dispersion contains povidone K30, soybean lecithin and acrylic resin IV, and the mass ratio between silymarin and other medical accessories in silymarin solid dispersion is silymarin:povidone K30:soybean lecithin:acrylic resin IV=1:1˜3:0.3˜0.8:0.2˜0.5. Compared with the existing formulations, the half life of the high-efficacy, long-acting formulation of silymarin disclosed in this invention is 2.3 times longer while the mean residence time (MRT) of which is 9.94 times longer; when tested in vivo in Beagle dogs, this new formulation of silymarin presents a smoother concentration-time curve and reaches a continuous release for 72 hours. This invention discloses its preparation method.
摘要翻译： 包含水飞蓟素固体分散体，含水飞蓟马的二氧化硅纳米颗粒，缓释基质材料和释放增强剂的高效，长效的水飞蓟素制剂，其中这些组分的质量比是水飞蓟素固体分散体：载有水飞蓟马的二氧化硅纳米颗粒： 缓释基质材料：释放增强剂= 1：0.5〜1.25：0.1〜0.3：0.1〜0.3; 所述载有水飞粒的二氧化硅纳米粒子的药物负载率为51.95％〜52.87％。 所述水飞蓟素固体分散体含有聚维酮K30，大豆卵磷脂和丙烯酸树脂IV，水飞蓟素等水飞蓟素固体分散体中的其他医疗配件的质量比为水飞蓟素：聚维酮K30：大豆卵磷脂：丙烯酸树脂IV = 1：1〜3：0.3 〜0.8：0.2〜0.5。 与现有制剂相比，本发明公开的水飞蓟素的高效长效制剂的半衰期为2.3倍，平均停留时间（MRT）为9.94倍; 当在Beagle犬体内测试时，这种水飞蓟素的新制剂呈现出更平滑的浓度 - 时间曲线并达到连续释放72小时。 本发明公开了其制备方法。
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