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公开(公告)号：US07945324B2
公开(公告)日：2011-05-17
申请号：US12165557
申请日：2008-06-30
IPC分类号： A61N1/39
CPC分类号： A61N1/0563 , A61N1/36564 , A61N1/3925 , A61N1/3956 , A61N1/3987
摘要： Various different implementations of lead systems are disclosed for use with implantable stimulation systems. Generally, the lead systems incorporate, within an elongate lead body, one or more electrical conduits that connect to one or more distal electrodes, and a liquid-filled pressure transmission catheter lumen that extends proximally from a distal entry port. Use of the lead systems allows accurate pressure sensing at a location near where the electrodes are positioned. In addition, a defibrillator lead is disclosed having such features, and a system using that lead is capable of directly monitoring pressure within a heart chamber, and using that information to confirm the delivery of a defibrillation pulse.
摘要翻译： 公开了引导系统的各种不同实施方式，用于可植入的刺激系统。 通常，引导系统在细长引线体内并入连接到一个或多个远端电极的一个或多个电导管，以及从远端入口向近侧延伸的充满液体的压力传导导管腔。 引线系统的使用允许在靠近电极定位的位置进行精确的压力感测。 此外，公开了具有这种特征的除颤器引线，并且使用该引线的系统能够直接监视心脏室内的压力，并且使用该信息来确认除颤脉冲的传递。
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公开(公告)号：US20090326598A1
公开(公告)日：2009-12-31
申请号：US12165557
申请日：2008-06-30
CPC分类号： A61N1/0563 , A61N1/36564 , A61N1/3925 , A61N1/3956 , A61N1/3987
摘要： Various different implementations of lead systems are disclosed for use with implantable stimulation systems. Generally, the lead systems incorporate, within an elongate lead body, one or more electrical conduits that connect to one or more distal electrodes, and a liquid-filled pressure transmission catheter lumen that extends proximally from a distal entry port. Use of the lead systems allows accurate pressure sensing at a location near where the electrodes are positioned. In addition, a defibrillator lead is disclosed having such features, and a system using that lead is capable of directly monitoring pressure within a heart chamber, and using that information to confirm the delivery of a defibrillation pulse.
摘要翻译： 公开了引导系统的各种不同实施方式，用于可植入的刺激系统。 通常，引导系统在细长引线体内并入连接到一个或多个远端电极的一个或多个电导管，以及从远端入口向近侧延伸的充满液体的压力传导导管腔。 引线系统的使用允许在靠近电极定位的位置进行精确的压力感测。 此外，公开了具有这种特征的除颤器引线，并且使用该引线的系统能够直接监视心脏室内的压力，并且使用该信息来确认除颤脉冲的传递。
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公开(公告)号：US20090326390A1
公开(公告)日：2009-12-31
申请号：US12164870
申请日：2008-06-30
IPC分类号： A61B5/00
CPC分类号： A61B5/02154 , A61B5/14542 , A61B5/1459 , A61N1/36557 , A61N1/36564 , A61N1/36585
摘要： Pressure and oxygen saturation monitoring devices and systems are disclosed. The devices, or portions thereof, can be implanted within a subject for monitoring blood pressure and oxygen saturation.
摘要翻译： 公开了压力和氧饱和度监测装置和系统。 可以将装置或其部分植入受试者内以监测血压和氧饱和度。
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4.发明授权Monitoring fluid in a subject using an electrode configuration providing negative sensitivity regions 有权使用提供负敏感区域的电极配置来监测受试者中的流体公开(公告)号：US07640056B2
公开(公告)日：2009-12-29
申请号：US11419123
申请日：2006-05-18
申请人： Andres Belalcazar
发明人： Andres Belalcazar
IPC分类号： A61B5/05
CPC分类号： A61B5/0537 , A61B5/4869
摘要： An amount of fluid in a thoracic or other region of a subject may be monitored by internally injecting an electrical energy stimulus (e.g., constant voltage source) through the region, detecting voltage resulting from the electrical energy stimulus, and calculating a fluid volume indicative signal. The injected energy stimulus creates a first lead field. The responsive voltage is detected using an electrode configuration that defines a second lead field, which is arranged in a negative sensitivity configuration with respect to the first lead field at the region being monitored.
摘要翻译： 可以通过在该区域内部注入电能刺激（例如，恒定电压源）来检测受试者的胸部或其他区域中的流体的量，检测由电能刺激产生的电压，以及计算流体体积指示信号 。 注入能量刺激产生了第一个引线场。 使用限定第二引线场的电极配置来检测响应电压，该引线场在被监视的区域处相对于第一引线场布置成负的灵敏度配置。
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5.发明申请METHOD AND APPARATUS FOR DETECTING FIBRILLATION USING CARDIAC LOCAL IMPEDANCE 有权使用心脏局部阻力检测纤维化的方法和装置公开(公告)号：US20080097539A1
公开(公告)日：2008-04-24
申请号：US11550923
申请日：2006-10-19
申请人： Andres Belalcazar
发明人： Andres Belalcazar
IPC分类号： A61N1/365
CPC分类号： A61N1/3622 , A61N1/3956
摘要： A cardiac rhythm management (CRM) system detects tachyarrhythmia using cardiac local impedance indicative of cardiac local wall motion. A cardiac local impedance signal indicative of an impedance of a cardiac region is sensed by using a pair of bipolar electrodes placed in that cardiac region. Tachyarrhythmia such as VF is detected by analyzing one or more cardiac local impedance signals sensed in one or more cardiac regions.
摘要翻译： 心律管理（CRM）系统使用指示心脏局部壁运动的心脏局部阻抗来检测快速性心律失常。 通过使用放置在该心脏区域中的一对双极电极来感测指示心脏区域的阻抗的心脏局部阻抗信号。 通过分析在一个或多个心脏区域中感测到的一个或多个心脏局部阻抗信号来检测诸如VF的快速性心律失常。
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公开(公告)号：US07184821B2
公开(公告)日：2007-02-27
申请号：US10726949
申请日：2003-12-03
IPC分类号： A61B5/05
CPC分类号： A61B5/0537 , A61B5/0809 , A61N1/372
摘要： Changes in fluid volume in a thoracic region, such as the lung, are detected by internally injecting a current through the region, detecting an induced voltage on the skin of the patient, and calculating an impedance value. A method for performing such a measurement includes injecting an electrical current between first and second internal electrodes that are implanted in the body and that are positioned such that a portion of the injected current flows through at least a portion of the region. The method also includes measuring a voltage between first and second external electrodes attached to an external surface of the skin of the body. The measured voltage is induced by the injected current. The method also includes calculating an impedance by taking the ratio of the measured voltage and the injected current, wherein the calculated impedance is related to the volume of fluid in the region.
摘要翻译： 通过在该区域内部注入电流，检测患者皮肤上的感应电压和计算阻抗值来检测胸部区域（例如肺）中的体积变化。 用于执行这种测量的方法包括在注入到体内的第一和第二内部电极之间注入电流，并将其定位成使得一部分注入的电流流过该区域的至少一部分。 该方法还包括测量附接到身体皮肤的外表面的第一和第二外部电极之间的电压。 测量的电压由注入电流引起。 该方法还包括通过获取测量电压和注入电流的比值来计算阻抗，其中所计算的阻抗与该区域中的流体体积相关。
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公开(公告)号：US20120089040A1
公开(公告)日：2012-04-12
申请号：US13325654
申请日：2011-12-14
申请人： Jeffrey E. Stahmann , Krzysztof Z. Siejko , Carlos Haro , Abhilash Patangay , Gerrard M. Carlson , Andres Belalcazar
发明人： Jeffrey E. Stahmann , Krzysztof Z. Siejko , Carlos Haro , Abhilash Patangay , Gerrard M. Carlson , Andres Belalcazar
IPC分类号： A61B7/00
CPC分类号： A61N1/36514 , A61B5/0031 , A61B5/021 , A61B5/024 , A61B5/053 , A61B5/08 , A61B5/0816 , A61B5/1116 , A61B5/4806 , A61B5/686 , A61B5/7275 , A61B7/04 , A61N1/36578
摘要： A system and method to sense heart sounds with one or more implantable medical devices according to one or more signal processing parameters. The method alters one or more of the parameters as a function of one or more physiologic triggering events. The method then senses heart sounds with the one or more implantable medical devices according to at least the one or more altered signal processing parameters.
摘要翻译： 根据一个或多个信号处理参数用一个或多个可植入医疗装置感测心脏声音的系统和方法。 该方法将一个或多个参数改变为一个或多个生理触发事件的函数。 该方法然后根据至少一个或多个改变的信号处理参数用一个或多个可植入医疗装置感测心脏声音。
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8.发明申请Systems and Methods for Placing Electronic Devices into "Cautery-Safe" Mode 有权将电子设备放入“烧烤安全”模式的系统和方法公开(公告)号：US20110160782A1
公开(公告)日：2011-06-30
申请号：US12793374
申请日：2010-06-03
申请人： Keith Lurie , Barbara S. Gold , David Benditt , Andres Belalcazar
发明人： Keith Lurie , Barbara S. Gold , David Benditt , Andres Belalcazar
CPC分类号： A61N1/37264 , A61N1/3688 , A61N1/37 , A61N1/37247 , A61N1/3931
摘要： A method and device to enable a medical or surgical procedure using electro-cautery on a patient with an implantable device in a cautery-safe mode of operation. In one embodiment, the invention provides an electronic implantable device programmer having a computer processor, and a display screen configured to display information based on signals from the computer processor. The programmer also includes an input device, and a wireless transmitter controlled by the computer processor. The programmer display and input give the operator the option of programming an implanted electronic device in a cautery-safe mode. With this input, from the operator, instructions are provided in the programmer to transmit a signal from the wireless transmission device to the implanted electronic device to program the electronic device to be in a dedicated bipolar mode where electrical noise produced when operating an electro-cautery device during and medical/surgical procedure does not interfere with operation of the electronic device.
摘要翻译： 一种方法和装置，其使得能够在具有安全操作操作的可植入装置的患者身上使用电烙术进行医疗或外科手术。 在一个实施例中，本发明提供一种具有计算机处理器的电子可植入装置编程器，以及配置为基于来自计算机处理器的信号显示信息的显示屏。 编程器还包括输入设备和由计算机处理器控制的无线发射器。 编程器显示和输入使操作者可以选择在烧焦安全模式下对植入的电子设备进行编程。 通过该输入，从操作者处，在编程器中提供指令以将信号从无线传输设备发送到植入的电子设备，以将电子设备编程为专用的双极模式，其中在操作电烙铁时产生电噪声 设备在医疗/外科手术过程中不影响电子设备的操作。
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9.发明申请METHOD AND APPARATUS FOR DETECTING FIBRILLATION USING CARDIAC LOCAL IMPEDANCE 审中-公开使用心脏局部阻力检测纤维化的方法和装置公开(公告)号：US20110077540A1
公开(公告)日：2011-03-31
申请号：US12963239
申请日：2010-12-08
申请人： Andres Belalcazar
发明人： Andres Belalcazar
IPC分类号： A61B5/0464 , A61B5/0402 , A61N1/365
CPC分类号： A61N1/3622 , A61N1/3956
摘要： A cardiac rhythm management (CRM) system detects tachyarrhythmia using cardiac local impedance indicative of cardiac local wall motion. A cardiac local impedance signal indicative of an impedance of a cardiac region is sensed by using a pair of bipolar electrodes placed in that cardiac region. Tachyarrhythmia such as VF is detected by analyzing one or more cardiac local impedance signals sensed in one or more cardiac regions.
摘要翻译： 心律管理（CRM）系统使用指示心脏局部壁运动的心脏局部阻抗来检测快速性心律失常。 通过使用放置在该心脏区域中的一对双极电极来感测指示心脏区域的阻抗的心脏局部阻抗信号。 通过分析在一个或多个心脏区域中感测到的一个或多个心脏局部阻抗信号来检测诸如VF的快速性心律失常。
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公开(公告)号：US07840267B2
公开(公告)日：2010-11-23
申请号：US11690700
申请日：2007-03-23
IPC分类号： A61N1/368
CPC分类号： A61N1/36521 , A61B5/0031 , A61B5/053 , A61B5/0538 , A61B5/11 , A61B5/686 , A61B5/6869 , A61N1/3627 , A61N1/3684
摘要： An apparatus comprises a first impedance sensing circuit, a second sensing circuit, and an impedance-based cardiac dyssynchrony detector. The impedance sensing circuit senses an intracardiac local impedance signal that is indicative of a cardiac local wall motion of a first cardiac region from an implantable first bipolar pair of impedance sensing electrodes. The second sensing circuit is configured to produce a second sensor signal indicative of cardiovascular activity. The impedance-based cardiac dyssynchrony detector is configured for detecting cardiac dyssynchrony using a relationship between the first intracardiac local impedance signal and the second sensor signal. Other apparatuses and methods are disclosed.
摘要翻译： 一种装置包括第一阻抗感测电路，第二感测电路和基于阻抗的心脏不同步检测器。 阻抗感测电路感测指示来自可植入的第一双极对阻抗感测电极的第一心脏区域的心脏局部壁运动的心内局部阻抗信号。 第二感测电路被配置为产生指示心血管活动的第二传感器信号。 基于阻抗的心脏不同步检测器被配置为使用第一心内局部阻抗信号和第二传感器信号之间的关系来检测心脏不同步。 公开了其他装置和方法。
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