公开(公告)号：US20230304061A1

公开(公告)日：2023-09-28

申请号：US17918857

申请日：2021-04-23

Applicant: KANEKA CORPORATION

Inventor： Shingo KOBAYASHI ,  Nobuhiko DOJUN ,  Misato MATSUI ,  Naoaki TAOKA

IPC: C12P21/02 ,  C12N9/10 ,  C12N9/48 ,  C12N9/02 ,  C12N9/88

CPC classification number: C12P21/02 ,  C12N9/0051 ,  C12N9/1029 ,  C12N9/485 ,  C12N9/88 ,  C12Y108/01007 ,  C12Y203/0103 ,  C12Y304/11004 ,  C12Y304/19013 ,  C12Y401/99001

Abstract: This invention is intended to improve glutathione productivity by fermentation using microorganisms. This invention relates to a microbial strain capable of overexpression of γ-glutamylcysteine, bis-γ-glutamylcystine, γ-glutamylcystine, reduced glutathione, and/or oxidized glutathione in which the expression level of a gene encoding serine-O-acetyltransferase (EC:2.3.1.30) is enhanced and a method involving the use of such microbial strain.