公开(公告)号：US09146218B1

公开(公告)日：2015-09-29

申请号：US14254350

申请日：2014-04-16

申请人： KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS ,  KING ABDULAZIZ CITY FOR SCIENCE AND TECHNOLOGY

发明人： Basheer Chanbasha ,  Mousa Yaser Amayreh

IPC分类号： C07C43/00 ,  G01N30/72 ,  C07C41/34 ,  G01N30/02

CPC分类号： G01N30/7206 ,  C07C41/34 ,  C07C43/137 ,  G01N30/08 ,  G01N30/88 ,  G01N35/109 ,  G01N2030/025 ,  G01N2030/8804

摘要： A fully automated flow assisted-solid-phase microextraction (FA-SPME) is developed for the determination of chloroethers in aqueous samples. A CTC CombiPAL autosampler coupled with gas chromatography-mass spectrometry (GC-MS) is used to automate the extraction process. In this method, the SPME fiber is exposed to a sample in direct immersion. After exposure, the fiber is desorbed at the injection port of GC-MS.

摘要翻译： 开发了全自动流动辅助固相微萃取（FA-SPME），用于测定含水样品中的氯醚。 使用CTC CombiPAL自动进样器和气相色谱 - 质谱联用（GC-MS）自动进行萃取过程。 在该方法中，将SPME纤维直接浸入样品中。 曝光后，纤维在GC-MS的注入口解吸。

公开(公告)号：US20150301001A1

公开(公告)日：2015-10-22

申请号：US14254350

申请日：2014-04-16

申请人： KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS ,  KING ABDULAZIZ CITY FOR SCIENCE AND TECHNOLOGY

发明人： Basheer Chanbasha ,  Mousa Yaser Amayreh

IPC分类号： G01N30/72 ,  C07C41/34

CPC分类号： G01N30/7206 ,  C07C41/34 ,  C07C43/137 ,  G01N30/08 ,  G01N30/88 ,  G01N35/109 ,  G01N2030/025 ,  G01N2030/8804

摘要： A fully automated flow assisted-solid-phase microextraction (FA-SPME) is developed for the determination of chloroethers in aqueous samples. A CTC CombiPAL autosampler coupled with gas chromatography-mass spectrometry (GC-MS) is used to automate the extraction process. In this method, the SPME fiber is exposed to a sample in direct immersion. After exposure, the fiber is desorbed at the injection port of GC-MS.

摘要翻译： 开发了全自动流动辅助固相微萃取（FA-SPME），用于测定含水样品中的氯醚。 使用CTC CombiPAL自动进样器和气相色谱 - 质谱联用（GC-MS）自动进行萃取过程。 在该方法中，将SPME纤维直接浸入样品中。 曝光后，纤维在GC-MS的注入口解吸。

公开(公告)号：US09207219B1

公开(公告)日：2015-12-08

申请号：US14846523

申请日：2015-09-04

申请人： KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS ,  King Abdulaziz City for Science and Technology

发明人： Basheer Chanbasha ,  Mousa Yaser Amayreh

IPC分类号： C07C43/00 ,  G01N30/72 ,  G01N35/10 ,  G01N30/02 ,  C07C43/13

CPC分类号： G01N30/7206 ,  C07C41/34 ,  C07C43/137 ,  G01N30/08 ,  G01N30/88 ,  G01N35/109 ,  G01N2030/025 ,  G01N2030/8804

摘要： A fully automated flow assisted-solid-phase microextraction (FA-SPME) is developed for the determination of chloroethers in aqueous samples. A CTC CombiPAL autosampler coupled with gas chromatography-mass spectrometry (GC-MS) is used to automate the extraction process. In this method, the SPME fiber is exposed to a sample in direct immersion. After exposure, the fiber is desorbed at the injection port of GC-MS.

公开(公告)号：US09212979B2

公开(公告)日：2015-12-15

申请号：US14155429

申请日：2014-01-15

申请人： King Fahd University of Petroleum and Minerals ,  King Abdulaziz City for Science and Technology

发明人： Basheer Chanbasha ,  Mousa Yaser Amayreh

IPC分类号： G01N30/88 ,  G01N1/40 ,  G01N30/06 ,  H01J49/04 ,  B01D53/02 ,  G01N30/72 ,  G01N30/00

CPC分类号： G01N1/405 ,  B01D53/025 ,  G01N30/06 ,  G01N30/7206 ,  G01N30/88 ,  G01N2030/009 ,  G01N2030/062 ,  G01N2030/8804 ,  G01N2030/8813 ,  H01J49/0431

摘要： An automated headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry for the determination of four N-nitrosamines in groundwater samples is developed. Response surface methodology technique was employed to investigate the optimized extraction conditions of headspace solid-phase microextraction using CombiPAL autosampler. The method was applied to determine the N-nitrosamine concentrations in groundwater samples.

摘要翻译： 开发了自动化顶空固相微萃取与气相色谱 - 质谱联用，用于测定地下水样品中的四种N-亚硝胺。 采用响应面法技术研究了使用CombiPAL自动进样器的顶空固相微萃取的优化提取条件。 该方法用于确定地下水样品中的N-亚硝胺浓度。

公开(公告)号：US09207220B1

公开(公告)日：2015-12-08

申请号：US14846564

申请日：2015-09-04

申请人： KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS ,  King Abdulaziz City for Science and Technology

发明人： Basheer Chanbasha ,  Mousa Yaser Amayreh

IPC分类号： C07C43/00 ,  G01N30/72 ,  C07C41/34 ,  G01N30/02 ,  C07C43/13

CPC分类号： G01N30/7206 ,  C07C41/34 ,  C07C43/137 ,  G01N30/08 ,  G01N30/88 ,  G01N35/109 ,  G01N2030/025 ,  G01N2030/8804

摘要： A fully automated flow assisted-solid-phase microextraction (FA-SPME) is developed for the determination of chloroethers in aqueous samples. A CTC CombiPAL autosampler coupled with gas chromatography-mass spectrometry (GC-MS) is used to automate the extraction process. In this method, the SPME fiber is exposed to a sample in direct immersion. After exposure, the fiber is desorbed at the injection port of GC-MS.

公开(公告)号：US20170292939A1

公开(公告)日：2017-10-12

申请号：US15633812

申请日：2017-06-27

申请人： KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

发明人： Chanbasha BASHEER ,  Mousa Yaser Amayreh

IPC分类号： G01N33/18 ,  G01N30/88 ,  G01N30/06 ,  G01N35/10 ,  G01N30/72 ,  G01N30/24

CPC分类号： G01N33/1826 ,  G01N1/38 ,  G01N30/7206 ,  G01N30/88 ,  G01N2001/4061 ,  G01N2030/062 ,  G01N2030/884 ,  G01N2035/00554 ,  Y10T436/170769 ,  Y10T436/173845 ,  Y10T436/24 ,  Y10T436/255

摘要： An automated dispersive liquid-liquid microextraction method of detecting and quantifying N-nitrosamines in an aqueous sample. The method includes (a) extracting an aqueous solution comprising the N-nitrosamines by mixing an extraction solvent and a dispersive solvent with the aqueous solution, such that the N-nitrosamines, or a portion thereof, re-distribute from the aqueous solution to the extraction solvent, (b) permitting the resulting mixture in (a) to form a two-phase mixture comprising an aqueous phase comprising the aqueous solution with reduced amounts of the N-nitrosamines and an organic phase comprising the extraction solvent with the N-nitrosamines extracted from the aqueous solution, (c) injecting the organic phase, or a portion thereof, into an injection port of a gas chromatograph coupled with at least one mass spectrometer, and (d) analyzing the N-nitrosamines by gas chromatography and mass spectrometry to detect and quantify the concentration of the N-nitrosamines in the aqueous solution.

公开(公告)号：US09857347B2

公开(公告)日：2018-01-02

申请号：US15633812

申请日：2017-06-27

申请人： KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

发明人： Chanbasha Basheer ,  Mousa Yaser Amayreh

IPC分类号： G01N33/18 ,  G01N1/40 ,  G01N30/72 ,  G01N30/88 ,  G01N35/10 ,  G01N30/24 ,  G01N30/06 ,  G01N30/02 ,  G01N35/00

CPC分类号： G01N33/1826 ,  G01N1/38 ,  G01N30/7206 ,  G01N30/88 ,  G01N2001/4061 ,  G01N2030/062 ,  G01N2030/884 ,  G01N2035/00554 ,  Y10T436/170769 ,  Y10T436/173845 ,  Y10T436/24 ,  Y10T436/255

摘要： An automated dispersive liquid-liquid microextraction method of detecting and quantifying N-nitrosamines in an aqueous sample. The method includes (a) extracting an aqueous solution including the N-nitrosamines by mixing an extraction solvent and a dispersive solvent with the aqueous solution, such that the N-nitrosamines, or a portion thereof, re-distribute from the aqueous solution to the extraction solvent, (b) permitting the resulting mixture in (a) to form a two-phase mixture containing an aqueous phase containing the aqueous solution with reduced amounts of the N-nitrosamines and an organic phase including the extraction solvent with the N-nitrosamines extracted from the aqueous solution, (c) injecting the organic phase, or a portion thereof, into an injection port of a gas chromatograph coupled with at least one mass spectrometer, and (d) analyzing the N-nitrosamines by gas chromatography and mass spectrometry to detect and quantify the concentration of the N-nitrosamines in the aqueous solution.

公开(公告)号：US09759705B1

公开(公告)日：2017-09-12

申请号：US15065480

申请日：2016-03-09

申请人： KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

发明人： Chanbasha Basheer ,  Mousa Yaser Amayreh

IPC分类号： G01N33/18 ,  G01N1/40 ,  G01N30/72 ,  G01N35/10 ,  G01N30/24 ,  G01N30/06 ,  G01N30/02

CPC分类号： G01N33/1826 ,  G01N1/38 ,  G01N30/7206 ,  G01N30/88 ,  G01N2001/4061 ,  G01N2030/062 ,  G01N2030/884 ,  G01N2035/00554 ,  Y10T436/170769 ,  Y10T436/173845 ,  Y10T436/24 ,  Y10T436/255

摘要： An automated dispersive liquid-liquid microextraction method of detecting and quanta N-nitrosamines in an aqueous sample. The method includes (a) extracting an aqueous solution containing the N-nitrosamines by mixing an extraction solvent and a dispersive solvent with the aqueous solution, such that the N-nitrosamines, or a portion thereof, re-distribute from the aqueous solution to the extraction solvent, (b) permitting the resulting mixture in (a) to form a two-phase mixture containing an aqueous phase comprising containing the aqueous solution with reduced amounts of the N-nitrosamines and an organic phase containing the extraction solvent with the N-nitrosamines extracted from the aqueous solution, (c) injecting the organic phase, or a portion thereof, into an injection port of a gas chromatograph coupled with at least one mass spectrometer, and (d) analyzing the N-nitrosamines by gas chromatography and mass spectrometry to detect and quantify the concentration of the N-nitrosamines in the aqueous solution.