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    CONTROLLING LIGHT EXPOSURE FOR CIRCADIAN PHASE MANAGEMENT
    2.
    发明申请
    CONTROLLING LIGHT EXPOSURE FOR CIRCADIAN PHASE MANAGEMENT 审中-公开

    公开(公告)号：US20200094015A1

    公开(公告)日：2020-03-26

    申请号：US16580112

    申请日：2019-09-24

    申请人： KONINKLIJKE PHILIPS N.V.

    发明人： Michael Edward COLBAUGH ,  Mark Anthony BARTOLOMEO ,  Stefanida Kononov BLAKE ,  Surya Subrahmanya Sreeram VISSAPRAGADA VENKATA SATYA ,  Andreas Ralph MAIHOEFER ,  Xia CHEN ,  Boomika KALYAN

    IPC分类号： A61M21/02 ,  A61N5/06

    摘要： This disclosure pertains to a system configured to control light exposure for circadian phase management and/or light deficient disorders of a subject. The system comprises a user interface, physiological sensors configured to generate output signals conveying physiological data of the subject, and a light control valve configured to block or reduce blue light ambient radiation reaching eyes of the subject. Processors are in communication with the user interface, the physiological sensors, the light control valve, and radiation generators. The processors cause the system to receive physiological goals of the subject, determine a light control plan based on the physiological goals, the physiological data, environmental data, and time data. The system operates the light control valve to block or reduce blue light ambient radiation based on the light control plan, and generate, using the one or more radiation generators, therapeutic light radiation based on the light control plan.

    DETERMINING CORRECTED TIMING OF STIMULATION PROVIDED TO A SUBJECT DURING SLEEP
    3.
    发明申请
    DETERMINING CORRECTED TIMING OF STIMULATION PROVIDED TO A SUBJECT DURING SLEEP 审中-公开

    公开(公告)号：US20190336723A1

    公开(公告)日：2019-11-07

    申请号：US16466794

    申请日：2017-12-07

    申请人： KONINKLIJKE PHILIPS N.V.

    发明人： Gary Nelson GARCIA MOLINA ,  Anandi MAHADEVAN ,  Surya Subrahmanya Sreeram VISSAPRAGADA VENKATA SATYA

    IPC分类号： A61M21/02 ,  A61B5/00 ,  A61B5/0476

    摘要： The present disclosure pertains to determining timing of stimulation provided to a subject during sleep. The system receives a raw signal carrying information related to slow wave activity; buffers a portion of the raw signal; determines a timing of slow wave events in the buffered portion of the raw signal; filters the raw signal; determines a timing of slow wave events in the filtered raw signal; compares the timing of the slow wave events in the buffered portion of the raw signal to the timing of the slow wave events in the filtered raw signal; determines a first correction factor associated with reducing slow wave activity in the subject and a second correction factor associated with enhancing slow wave activity in the subject; and adjusts a timing of the stimulation provided to the subject during the sleep session based on the first and/or second correction factors.

    METHOD AND SYSTEM TO DELIVER TIMED AND GROUPED SENSORY STIMULATION
    5.
    发明申请
    METHOD AND SYSTEM TO DELIVER TIMED AND GROUPED SENSORY STIMULATION 审中-公开

    公开(公告)号：US20200306495A1

    公开(公告)日：2020-10-01

    申请号：US16832549

    申请日：2020-03-27

    申请人： KONINKLIJKE PHILIPS N.V.

    发明人： Gary Nelson GARCIA MOLINA ,  Jesse SALAZAR ,  Surya Subrahmanya Sreeram VISSAPRAGADA VENKATA SATYA ,  Antonio AQUINO ,  Birpal Singh SACHDEV

    IPC分类号： A61M21/02 ,  G16H40/60 ,  G16H10/60

    摘要： A system for delivering sensory stimulation comprises a sensor configured to measure brain activity information of a patient during a sleep session; a sensory stimulator configured to deliver sensory simulation to the patient during the sleep session; and a computer system. One or more physical processors are programmed with computer program instructions which, when executed cause the computer system to: determine a first stimulation profile, a second stimulation profile, or a combination stimulation profile thereof based on obtained sleep cycle information and/or obtained cognitive domain information; and provide input to the sensory stimulator based on the determined stimulation profile, the provided input causing the sensory stimulator to deliver the sensory simulations to the patient based on the determined stimulation profile during the detected slow wave sleep in the patient.

    SYSTEM AND METHOD FOR DETERMINING REFERENCE SLOW WAVE ACTIVITY IN A SUBJECT
    7.
    发明申请
    SYSTEM AND METHOD FOR DETERMINING REFERENCE SLOW WAVE ACTIVITY IN A SUBJECT 审中-公开

    公开(公告)号：US20200077919A1

    公开(公告)日：2020-03-12

    申请号：US16466357

    申请日：2017-12-01

    申请人： KONINKLIJKE PHILIPS N.V.

    发明人： Gary Nelson GARCIA MOLINA ,  Anandi MAHADEVAN ,  Surya Subrahmanya Sreeram VISSAPRAGADA VENKATA SATYA ,  Annette KAPITAN

    IPC分类号： A61B5/0484 ,  A61B5/00 ,  A61M21/00

    摘要： The present disclosure pertains to a reference slow wave activity metric determination system. Instead of collecting information during sleep sessions without stimulation (e.g., baseline and/or sham sessions) to determine a reference amount of slow wave activity in a subject, the present system is configured to build a model between stimulation properties and slow wave enhancement, and determine the reference amount of slow wave activity in the subject (e.g., corresponding to what would occur during baseline sleep and/or sham sessions) using the model. Advantageously, this approach does not require performance of baseline and/or sham sleep sessions, and enables personalization of the reference amount of slow wave activity, which dynamically increases its accuracy as more information is collected.