公开(公告)号：US11846882B2

公开(公告)日：2023-12-19

申请号：US16923965

申请日：2020-07-08

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Maesoon Im ,  Byung Chul Lee ,  Young Jun Yoon ,  Jin Soo Park ,  Seung Min Kwak

IPC: G03F7/004 ,  A61N1/05 ,  A61B5/24

CPC classification number: G03F7/0041 ,  A61B5/24 ,  A61N1/0529 ,  A61B2562/125

Abstract: Disclosed is a method for manufacturing a high-density neural probe including needles having various forms. The method, in which only a photolithography process and an etching process are used, simplifies a manufacturing process of the neural probe, minimizes changes in the characteristics of the neural probe depending on process equipment or conditions, and may thus ensure a high yield, thereby being advantageous in terms of commercialization. In addition, various forms of needles may be manufactured depending on the shape of patterns included in a mask, the height of the needles may be controlled by adjusting the size of the patterns and the gap between the patterns, and thereby, a neural probe having a plurality of needles having different heights may be manufactured.

公开(公告)号：US11285186B2

公开(公告)日：2022-03-29

申请号：US16555950

申请日：2019-08-29

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION

Inventor： Chu Won Nho ,  Hak Cheol Kwon ,  Ji-Hye Yoo ,  Jaeyoung Kwon ,  Jin Soo Park ,  Hyuk-Jai Jang ,  Seong-Su Kim ,  Cheon Soo Park ,  Hwa-Mi Lee ,  Hee Ju Lee

IPC: A61K36/28 ,  A61P9/10 ,  A23L33/00 ,  A23L33/105

Abstract: Provided are a pharmaceutical composition including a Crepidiastrum denticulatum extract as an active ingredient; and a method for preventing or treating ischemia-reperfusion injury in a subject by using a food composition or the pharmaceutical composition.

公开(公告)号：US11097943B2

公开(公告)日：2021-08-24

申请号：US16294032

申请日：2019-03-06

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Byung Chui Lee ,  Jin Soo Park ,  Mintack Oh ,  Jin Hyun Kim

IPC: B81C1/00 ,  H01L41/09 ,  H01L41/113 ,  H01L21/762 ,  H01L29/78

Abstract: A membrane device includes a trench substrate having trenches and a membrane having wrinkles. The membrane is not bonded to the trenches of the trench substrate but is bonded to the surface of the trench substrate in the shoulders of the trenches. Hills and valleys are alternately arranged in the membrane along the trenches. The membrane device can be used in various applications (for example, sensors) based on variations in the electrical properties of the membrane caused by a change in the shape of the wrinkles (a change in the strain) of the membrane in response to a change in the internal or external environment of the trenches.

公开(公告)号：US20190322524A1

公开(公告)日：2019-10-24

申请号：US16294032

申请日：2019-03-06

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Byung Chul Lee ,  Jin Soo Park ,  Mintack Oh ,  Jin Hyun Kim

IPC: B81C1/00 ,  H01L21/762

Abstract: A membrane device includes a trench substrate having trenches and a membrane having wrinkles. The membrane is not bonded to the trenches of the trench substrate but is bonded to the surface of the trench substrate in the shoulders of the trenches. Hills and valleys are alternately arranged in the membrane along the trenches. The membrane device can be used in various applications (for example, sensors) based on variations in the electrical properties of the membrane caused by a change in the shape of the wrinkles (a change in the strain) of the membrane in response to a change in the internal or external environment of the trenches.