公开(公告)号：US20180028600A1

公开(公告)日：2018-02-01

申请号：US15650272

申请日：2017-07-14

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Yeon-Sun HONG ,  Yoo Soo YANG ,  Cherl Hyun JEONG ,  In-San KIM

IPC: A61K38/16 ,  A61K45/06 ,  A61K9/127

CPC classification number: A61K38/162 ,  A61K9/1271 ,  A61K45/06 ,  A61P3/10 ,  A61P21/00

Abstract: Provided is a recombinant exosome, and more specifically, to a recombinant exosome obtained from a eukaryotic cell transfected for the expression of a glucose transporter protein (GLUT) and a membrane fusogenic protein, and use thereof.

公开(公告)号：US20240358645A1

公开(公告)日：2024-10-31

申请号：US18652504

申请日：2024-05-01

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Yeon-Sun HONG ,  Yoo Soo YANG ,  In-San KIM

IPC: A61K9/48 ,  A61K31/337 ,  A61K31/407 ,  A61K31/704 ,  A61K38/47 ,  A61K39/395 ,  A61K41/00 ,  A61K45/06 ,  A61N5/10 ,  A61P35/00

CPC classification number: A61K9/48 ,  A61K31/337 ,  A61K31/407 ,  A61K31/704 ,  A61K38/47 ,  A61K39/3955 ,  A61K41/0057 ,  A61K45/06 ,  A61P35/00 ,  C12Y302/01035 ,  A61N5/10 ,  A61N2005/1098

Abstract: The present invention relates to a recombinant exosome containing hyaluronidase and a use thereof, and more particularly to a recombinant exosome that presents hyaluronidase on its surface and use thereof as an anticancer agent.

公开(公告)号：US20230226215A1

公开(公告)日：2023-07-20

申请号：US17937437

申请日：2022-09-30

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  REONEBIO

Inventor： In-San KIM ,  Gi-Hoon NAM ,  Yeon-Sun HONG ,  Seong Eon CHO

IPC: A61K47/69 ,  A61K38/18 ,  A61K38/17 ,  A61K35/28 ,  A61P17/02 ,  A61K9/06

CPC classification number: A61K47/6911 ,  A61K38/1808 ,  A61K38/179 ,  A61K38/1796 ,  A61K38/177 ,  A61K38/1774 ,  A61K35/28 ,  A61P17/02 ,  A61K9/06

Abstract: The present invention provides a recombinant exosome comprising a membrane-bound EGF protein on the surface of the recombinant exosome and provides a use of the recombinant exosome.

公开(公告)号：US20190307794A1

公开(公告)日：2019-10-10

申请号：US16379523

申请日：2019-04-09

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Yeon-Sun HONG ,  Hyo Suk Kim ,  Yoo Soo Yang ,  Sun Hwa Kim ,  In-San Kim ,  Ick Chan Kwon

IPC: A61K35/15 ,  C12N5/0786 ,  C12N5/0784 ,  C12N5/0775 ,  A61K9/127 ,  C12N5/00

Abstract: The present invention relates to a method of inducing trans-differentiating a first type of immune cell into a second type of immune cell comprising: isolating exosomes from the second type of immune cell that has undergone differentiation, and treating the first type of immune cell or a cell population including the first type of immune cell with the isolated exosomes in vitro.