公开(公告)号：US11345667B2

公开(公告)日：2022-05-31

申请号：US16852820

申请日：2020-04-20

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Taejung Kim ,  Jungyeob Ham ,  Young Tae Park

IPC: C07D235/02

Abstract: The present invention relates to a method of preparing pactalactam represented by Formula 5 below using a total synthesis method:

公开(公告)号：US11648284B2

公开(公告)日：2023-05-16

申请号：US17205162

申请日：2021-03-18

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jin Chul Kim ,  Dorjsembe Banzragch ,  Eun Ha Lee ,  Sung Chul Hong ,  Jung Yeob Ham ,  Young Tae Park ,  Chu Won Nho

IPC: A61K36/23 ,  A61P17/06 ,  A23L33/00 ,  A23L33/105 ,  A23L33/15 ,  A23L29/00 ,  A61K9/20 ,  A61K9/00 ,  A61K9/16 ,  A23L2/68 ,  A61K8/9789

CPC classification number: A61K36/23 ,  A23L2/68 ,  A23L29/015 ,  A23L29/035 ,  A23L33/105 ,  A23L33/15 ,  A23L33/30 ,  A61K8/9789 ,  A61K9/0019 ,  A61K9/0095 ,  A61K9/1617 ,  A61K9/1682 ,  A61K9/2018 ,  A61K9/2059 ,  A61K9/2095 ,  A61P17/06 ,  A61K2236/33 ,  A61K2236/50 ,  A61K2800/805 ,  A61K2800/91 ,  A61K2800/92

Abstract: Disclosed is a composition for ameliorating, preventing or treating an autoimmune skin disease, containing a Musan box (Sphallerocarpus gracilis) extract or a fraction thereof as an active ingredient.

公开(公告)号：US11618002B2

公开(公告)日：2023-04-04

申请号：US17221591

申请日：2021-04-02

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jungyeob Ham ,  Taejung Kim ,  Bong Chul Chung ,  Sungdo Ha ,  Seok Lee ,  Young Tae Park ,  Pilju Choi

IPC: B01J19/12

Abstract: A large capacity natural material composition conversion apparatus using a microwave with a preset pressure function includes a chamber including a sealed reaction space accommodating a material, an radiator configured to heat the material by radiating a microwave into the reaction space, a pressure regulator configured to regulate a pressure of the reaction space by supplying a gas into the reaction space, and a controller configured to control the pressure regulator and the radiator, and preliminarily increase a pressure of the reaction space by controlling the pressure regulator before heating the material.

公开(公告)号：US11554149B2

公开(公告)日：2023-01-17

申请号：US17035690

申请日：2020-09-29

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jungyeob Ham ,  Taejung Kim ,  Bong Chul Chung ,  Seok Lee ,  Bong Geun Song ,  Sungdo Ha ,  Young Tae Park ,  Pilju Choi ,  Hoon Ryu

IPC: A61K36/185 ,  A23L33/105 ,  A61K8/9789 ,  A61K8/34 ,  A61K31/05 ,  B01J19/12

Abstract: Provided are: a method of preparing a cannabis processed product having an increased CBD content in an efficient and economic manner, through a decarboxylation reaction by continuous microwave irradiation of a cannabis extract; and use of a processed product having an increased CBD content prepared by the method, a fraction thereof, and a single ingredient of CBD, in foods, drugs, and cosmetics.

公开(公告)号：US12083490B2

公开(公告)日：2024-09-10

申请号：US17590292

申请日：2022-02-01

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Taejung Kim ,  Jungyeob Ham ,  Young Tae Park ,  Pilju Choi ,  Joonyeon Chang

IPC: B01J19/12 ,  B01J19/24

CPC classification number: B01J19/126 ,  B01J19/243

Abstract: According to an aspect of the disclosure, there is provided a microwave reactor including a container for storing a bath fluid, a tube including an inlet at one end through which a target fluid is introduced, an outlet at another end through which the target fluid is discharged, wherein at least a portion of the tube is submerged in the bath fluid, and at least one radiator located outside the container and configured to irradiate microwaves into the container.

公开(公告)号：US11547735B2

公开(公告)日：2023-01-10

申请号：US17205468

申请日：2021-03-18

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jin Chul Kim ,  Dorjsembe Banzragch ,  Eun Ha Lee ,  Sung Chul Hong ,  Young Tae Park ,  Jung Yeob Ham ,  Chu Won Nho

IPC: A61K36/00 ,  A61K36/71 ,  A61K9/00 ,  A61K8/9789 ,  A61P17/06 ,  A61Q19/00 ,  A23L33/00 ,  A23L2/52 ,  A23L33/105

Abstract: Disclosed is a composition for ameliorating, preventing or treating an autoimmune skin disease, containing a Thalictrum (Thalictrum squarrosum steph) extract or a fraction thereof as an active ingredient.

公开(公告)号：US11273192B2

公开(公告)日：2022-03-15

申请号：US16428626

申请日：2019-05-31

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jungyeob Ham ,  Taejung Kim ,  Young Tae Park ,  Kyusun Kim ,  Pilju Choi ,  Seon-Jun Choi ,  Bong Geun Song ,  Jae Young Choi

IPC: A61K36/258 ,  A23L33/105 ,  A61K8/9789 ,  A61K31/704 ,  A61Q19/08 ,  A61K8/63

Abstract: Provided are a method of efficiently producing a ginseng leaf extract including rare ginsenosides Rg6, Rk3, and Rh4 in increased amounts, and use of a ginseng leaf extract produced by the method.

公开(公告)号：US10933033B2

公开(公告)日：2021-03-02

申请号：US16282203

申请日：2019-02-21

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jungyeob Ham ,  Young Tae Park ,  Taejung Kim ,  Young seok Kim ,  Pilju Choi ,  Kyusun Kim ,  SeonJun Choi ,  BongGeun Song ,  Kisung Kang ,  Buyng Su Hwang ,  Dahae Lee ,  Jihoon Song

IPC: A61K31/122 ,  A61K33/243 ,  A61P13/12 ,  A61K36/062 ,  A61K31/05 ,  A61K31/09

Abstract: A composition for preventing or reducing nephrotoxicity, and use thereof are provided, the composition including a Hypoxylon truncatum extract or an active component thereof.