公开(公告)号：US20210317492A1

公开(公告)日：2021-10-14

申请号：US17273886

申请日：2019-09-05

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Dong Hyun KIM ,  Eun-Ju YUN

IPC: C12P19/02 ,  C07H1/00 ,  C12P17/04 ,  C07H17/04

Abstract: The present invention relates to a method for chemical production of 3,6-anhydro-L-galactitol (L-AHGoI), which is a novel sugar alcohol, and agarobititol (ABol), which is a disaccharide having the same agarobititol as a reductant end thereof, from sea algae.

公开(公告)号：US20200165646A1

公开(公告)日：2020-05-28

申请号：US16084144

申请日：2017-03-31

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Kyoung Heon KIM ,  ln-Geol CHOI ,  Sora YU ,  Eun-Ju YUN ,  Kyung-mun CHO

IPC: C12P19/02

Abstract: The present invention relates to a novel method for purifying 3,6-anhydro-L-galactose by using microorganisms and provides an effect of improving the production yield of 3,6-anhydro-L-galactose by using microorganisms during purification after enzymatic hydrolysis of agarose or agar.

公开(公告)号：US20200071737A1

公开(公告)日：2020-03-05

申请号：US16467129

申请日：2017-11-24

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Sang-Hyun LEE ,  Dong-Hyun KIM ,  Eun-Ju YUN

IPC: C12P19/14 ,  C07H3/04 ,  C12P19/02

Abstract: The present invention relates to a method for producing anhydrous galactose derived from seaweed, and provides an improved production yield rate of 3,6-anhydro-L-galactose by using microorganisms during acid treatment, neutralization, and purification after enzymatic hydrolysis, of agarose or agar.

公开(公告)号：US20220220490A1

公开(公告)日：2022-07-14

申请号：US17273621

申请日：2019-09-05

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Yong Su JIN ,  Dong-Hyun KIM ,  Eun-Ju YUN

IPC: C12N15/81 ,  C07K14/195 ,  C12N9/38 ,  C12P7/18

Abstract: The present invention relates to a method for biologically producing, from seaweeds, 3,6-anhydro-L-galactitol (L-AHGol) which is a novel sugar alcohol, and agarobititol (ABol) which is in a disaccharide form having 3,6-anhydro-L-galactitol (L-AHGol) as a reducing end, by using a genetic engineering technique in GRAS strains.

公开(公告)号：US20200078383A1

公开(公告)日：2020-03-12

申请号：US16349885

申请日：2017-11-15

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Eun-Ju YUN ,  Sora YU ,  Dong-Hyun KIM ,  Sang-Hyun LEE ,  Jung Yeon KIM

IPC: A61K31/702 ,  A61K31/7016 ,  A61K31/729 ,  A61K8/73 ,  A61Q11/00 ,  A61P31/04 ,  A61K8/60 ,  A61P1/02 ,  A61K9/00 ,  A23L33/125

Abstract: The present invention relates to a use of an agarobiose or agarooligosaccharides having anticariogenic activity. More specifically, a lower concentration of agarobiose or agarooligosaccharides than the concentration of xylitol suppresses the growth of Streptococcus mutans and suppresses acid production, and thus can be used for anti-cariogenic purposes.

公开(公告)号：US20200338101A1

公开(公告)日：2020-10-29

申请号：US16765359

申请日：2018-11-15

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Yong-Su JIN ,  Eun-Ju YUN ,  Sora YU ,  Jaewon LEE

IPC: A61K31/7004 ,  A61K31/7016 ,  A61K31/729 ,  A61K8/60 ,  A23L33/125 ,  C12P19/04 ,  C12P19/18

Abstract: The present invention relates to a preparation method for various novel fucosyl oligosaccharides and a use thereof. More specifically, the present invention allows a preparation of various novel fucosyl oligosaccharides through an enzymatic reaction with α-1,2-fucosyltransferase using a GDP-L-fucose donor and various glucose acceptors and an establishment of probiotic characteristics thereof, and thus has an effect of providing uses as materials for medicines, food, cosmetic products, and the like.

公开(公告)号：US20200232957A1

公开(公告)日：2020-07-23

申请号：US16630921

申请日：2018-07-05

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Kyung-mun CHO ,  Eun-Ju YUN ,  Dong-Hyun KIM

IPC: G01N30/88 ,  G01N30/86

Abstract: The present invention relates to a method for quantifying 3,6-anhydro-L-galactose using high-performance liquid chromatography and a differential refractometric index detector, whereby L-AHG and D-galactose, which are saccharification products of agarose or agar, can be independently quantified by controlling the separation conditions of the high-performance liquid chromatography/differential refractive index detector, even though the two materials are difficult to separate due to having similar molecular weights and structures.

公开(公告)号：US20190024069A1

公开(公告)日：2019-01-24

申请号：US16067730

申请日：2017-01-17

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  In-Geol CHOI ,  Jung Hyun KIM ,  Eun-Ju YUN

IPC: C12N9/38 ,  C12P19/02 ,  C12P19/14

Abstract: The present invention relates to a heat-resistant agarase and a monosaccharide production method using same. More particularly, in the present invention, a heat-resistant agarase may be used to produce galactose and 3,6-anhydro-L-galactose at high yield by efficiently breaking down agarose or agar without a chemical pretreatment, a neutralization process, or an agarotriose hydrolase treatment process.