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    Preparation of l-isoleucine by fermentation
    6.
    发明授权
    Preparation of l-isoleucine by fermentation 失效
    通过发酵制备L-精油

    公开(公告)号：US3671396A

    公开(公告)日：1972-06-20

    申请号：US3671396D

    申请日：1969-03-05

    申请人： KYOWA HAKKO KOGYO KK

    发明人： NAKAYAMA KIYOSHI ,  HAGINO HIROSHI

    IPC分类号： C12P13/06 ,  C12D13/06

    CPC分类号： C12P13/06 ,  Y10S435/83 ,  Y10S435/84 ,  Y10S435/843 ,  Y10S435/859 ,  Y10S435/872 ,  Y10S435/874 ,  Y10S435/875 ,  Y10S435/888

    摘要： L-isoleucine is prepared by culturing a hydrocarbon assimilable microorganism in a culture medium containing hydrocarbon as the main carbon source and Alpha -aminobutyric acid, hydroxybutyric acid, threonine or mixtures thereof or non-toxic salts thereof. Microorganisms of the genera Corynebacterium, Brevibacterium, Arthrobacter, Micrococcus, Pseudomonas, Nocardia, Streptomyces, etc., are particularly suitable for use in the process.

    摘要翻译： 通过在含有烃作为主要碳源和α-氨基丁酸，羟基丁酸，苏氨酸或其混合物或其无毒盐的培养基中培养烃同化微生物来制备L-异亮氨酸。 棒状杆菌属，短杆菌属，节杆菌属，微球菌属，假单胞菌属，诺卡氏菌属，链霉菌属等的微生物特别适用于该方法。

    Process for preparing L-phenylalanine
    8.
    发明授权
    Process for preparing L-phenylalanine 失效
    L-苯丙氨酸的制备方法

    公开(公告)号：US3917511A

    公开(公告)日：1975-11-04

    申请号：US34522673

    申请日：1973-03-26

    申请人： KYOWA HAKKO KOGYO KK

    发明人： NAKAYAMA KIYOSHI ,  HAGINO HIROSHI

    IPC分类号： C12P13/22 ,  C12D13/06

    CPC分类号： C12P13/222 ,  Y10S435/822

    摘要： L-phenylalanine is produced in substantial yield by fermentation from an L-phenylalanine-producing strain of Microbacterium ammoniaphilum. Specifically mutated strains of the above noted bacteria that exhibit resistance to at least one compound selected from the group consisting of tyrosine, phenylalanine and analogues thereof, produce large amounts of L-phenylalanine when cultured in a suitable nutrient medium.

    摘要翻译： 通过从产生L-苯丙氨酸的微生物微生物菌株发酵，实质上产生L-苯丙氨酸。 对于选自酪氨酸，苯丙氨酸及其类似物的至少一种化合物表现出抗性的上述细菌的特异突变菌株在合适的营养培养基中培养时产生大量的L-苯丙氨酸。