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公开(公告)号:US10954348B2
公开(公告)日:2021-03-23
申请号:US16040871
申请日:2018-07-20
发明人: Jeongsoo Yoo , Woonghee Lee
IPC分类号: C08J3/24 , A61K9/51 , A61K51/06 , B82Y5/00 , C08G65/30 , C08B37/00 , A61K47/69 , A61K9/06 , A61K49/18 , A61K51/12 , C08G81/00 , C08B15/00 , C08L71/02 , C08H1/00 , C08B33/04 , C08B37/18 , C08G65/34 , B01J19/08 , C07H3/06 , C08B37/16 , C08B37/02 , C08B37/08
摘要: The present invention relates to a biocompatible nanoparticle and a use thereof and, more specifically, to a biocompatible nanoparticle formed by irradiation an electron beam to an aqueous solution comprising at least one substance selected from the group consisting of a polysaccharide, a derivative thereof and a polyethylene glycol, thereby inducing inter-molecular cross-linking or intra-molecular cross-linking, and to a use of the biocompatible nanoparticle in a drug carrier, a contrast agent, a diagnostic agent or an intestinal adhesion prevention agent or for disease prevention and treatment.
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公开(公告)号:US20240336632A1
公开(公告)日:2024-10-10
申请号:US18295000
申请日:2022-08-04
发明人: Jeongsoo Yoo , Kyungwon Kim
CPC分类号: C07F1/08 , A61K51/0482 , A61K51/1234 , A61K2121/00 , A61K2123/00 , C07B2200/05
摘要: The present invention relates to a novel compound comprising an ester group and uses thereof and, more particularly, to a novel compound that exhibits excellent visualization ability in a tumor by using the difference in activity of esterase for each organ in the body, and to uses therefor for diagnosing or treating cancer. A novel compound of chemical Formulas 1 to 8 according to the present invention exhibits selectivity according to the difference in activity of esterase for each organ due to ester residue in a structure, and thus is extremely effective in visualizing pancreatic cancer, etc.
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公开(公告)号:US20180327554A1
公开(公告)日:2018-11-15
申请号:US16040871
申请日:2018-07-20
发明人: Jeongsoo Yoo , Woonghee Lee
IPC分类号: C08J3/24 , A61K47/69 , A61K51/12 , A61K49/18 , C08B37/02 , C08G65/34 , C08G81/00 , C08B37/08 , C08B37/00 , C08B37/16 , C07H3/06 , A61K9/06 , B01J19/08
CPC分类号: C08J3/246 , A61K9/06 , A61K47/50 , A61K47/6935 , A61K47/6939 , A61K49/18 , A61K49/1818 , A61K51/12 , A61K51/1244 , B01J19/08 , B01J19/085 , B01J2219/0877 , B01J2219/12 , B82Y5/00 , C07H3/06 , C08B37/0006 , C08B37/0012 , C08B37/0021 , C08B37/003 , C08B37/0072 , C08B37/0084 , C08G65/34 , C08G81/00 , C08G2270/00 , C08J2305/00 , C08J2305/02 , C08J2305/04 , C08J2305/08 , C08J2305/16
摘要: The present invention relates to a biocompatible nanoparticle and a use thereof and, more specifically, to a biocompatible nanoparticle formed by irradiation an electron beam to an aqueous solution comprising at least one substance selected from the group consisting of a polysaccharide, a derivative thereof and a polyethylene glycol, thereby inducing inter-molecular cross-linking or intra-molecular cross-linking, and to a use of the biocompatible nanoparticle in a drug carrier, a contrast agent, a diagnostic agent or an intestinal adhesion prevention agent or for disease prevention and treatment.
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