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公开(公告)号:US20110178325A1
公开(公告)日:2011-07-21
申请号:US12689198
申请日:2010-01-18
申请人: Kang-Wei Chang , Yen-Hung Tu , Shih-Ying Lee , Jenn-Tzong Chen , Chia-Chieh Chen , Wuu-Jyh Lin
发明人: Kang-Wei Chang , Yen-Hung Tu , Shih-Ying Lee , Jenn-Tzong Chen , Chia-Chieh Chen , Wuu-Jyh Lin
IPC分类号: C07C255/34
CPC分类号: C07C253/30 , C07B2200/05 , C07C255/42
摘要: Disclosed is an automatic process for synthesizing F-18-FDDNP. The automatic process includes a preparation subroutine and a synthesis subroutine. The automatic process is efficient and simple. That is, it can be used to produce a large amount of chemicals in a short period of time. Furthermore, it reduces the risk of human exposure to radiation.
摘要翻译: 公开了一种合成F-18-FDDNP的自动化方法。 自动处理包括准备子程序和合成子程序。 自动过程高效简单。 也就是说,它可以在短时间内用于生产大量的化学品。 此外,它降低了人体接触辐射的风险。
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公开(公告)号:US20130072672A1
公开(公告)日:2013-03-21
申请号:US13237067
申请日:2011-09-20
申请人: Li-Yuan Huang , Yen-Hung Tu , Wen-Chin Su , Jenn-Tzong Chen , Ting-Shien Duh , Wuu-Jyh Lin
发明人: Li-Yuan Huang , Yen-Hung Tu , Wen-Chin Su , Jenn-Tzong Chen , Ting-Shien Duh , Wuu-Jyh Lin
IPC分类号: C07H21/00
CPC分类号: C07H19/06
摘要: The present invention establishes a fast and simple [F-18] FLT synthesis process. Solid extraction units are used for purification to achieve an equally high and constant radiochemical yield and purity in a short period of time. By using a separation method, the impurities are reduced successfully while the total synthesis time is shortened. The radiochemical purity and the corrected radiochemical yield are both high.
摘要翻译: 本发明建立了快速简单的[F-18] FLT合成方法。 固体提取单元用于纯化,以在短时间内实现同样高且恒定的放射化学产率和纯度。 通过使用分离方法,在总合成时间缩短的同时成功地降低杂质。 放射化学纯度和校正放射化学产率都很高。
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公开(公告)号:US09163054B2
公开(公告)日:2015-10-20
申请号:US13237067
申请日:2011-09-20
申请人: Li-Yuan Huang , Yen-Hung Tu , Wen-Chin Su , Jenn-Tzong Chen , Ting-Shien Duh , Wuu-Jyh Lin
发明人: Li-Yuan Huang , Yen-Hung Tu , Wen-Chin Su , Jenn-Tzong Chen , Ting-Shien Duh , Wuu-Jyh Lin
CPC分类号: C07H19/06
摘要: The present invention establishes a fast and simple [F-18] FLT synthesis process. Solid extraction units are used for purification to achieve an equally high and constant radiochemical yield and purity in a short period of time. By using a separation method, the impurities are reduced successfully while the total synthesis time is shortened. The radiochemical purity and the corrected radiochemical yield are both high.
摘要翻译: 本发明建立了快速简单的[F-18] FLT合成方法。 固体提取单元用于纯化,以在短时间内实现同样高且恒定的放射化学产率和纯度。 通过使用分离方法,在总合成时间缩短的同时成功地降低杂质。 放射化学纯度和校正放射化学产率都很高。
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公开(公告)号:US20080041719A1
公开(公告)日:2008-02-21
申请号:US11500936
申请日:2006-08-09
申请人: Wuu-Jyh Lin , Mao-Hsung Chang , Ping-Yen Huang , Jenn-Tzong Chen , Ting-Shien Duh , Dow-Che Chen , Kuo-Yuan Chu
发明人: Wuu-Jyh Lin , Mao-Hsung Chang , Ping-Yen Huang , Jenn-Tzong Chen , Ting-Shien Duh , Dow-Che Chen , Kuo-Yuan Chu
IPC分类号: C23C14/00
CPC分类号: H01J37/3497 , H01J37/3435
摘要: A liquid and a gas is constantly filled into a target chamber of a target. Then the liquid and the gas flow around the chamber and are flown out. By doing so, the target is effectively cooled down.
摘要翻译: 液体和气体不断地被填充到目标的靶室中。 然后液体和气体流过室并流出。 通过这样做,目标被有效地冷却下来。
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公开(公告)号:US07678248B2
公开(公告)日:2010-03-16
申请号:US11500936
申请日:2006-08-09
申请人: Wuu-Jyh Lin , Mao-Hsung Chang , Ping-Yen Huang , Jenn-Tzong Chen , Ting-Shien Duh , Dow-Che Chen , Kuo-Yuan Chu
发明人: Wuu-Jyh Lin , Mao-Hsung Chang , Ping-Yen Huang , Jenn-Tzong Chen , Ting-Shien Duh , Dow-Che Chen , Kuo-Yuan Chu
IPC分类号: C23C14/00
CPC分类号: H01J37/3497 , H01J37/3435
摘要: A liquid and a gas is constantly filled into a target chamber of a target. Then the liquid and the gas flow around the chamber and are flown out. By doing so, the target is effectively cooled down.
摘要翻译: 液体和气体不断地被填充到目标的靶室中。 然后液体和气体流过室并流出。 通过这样做,目标被有效地冷却下来。
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公开(公告)号:US20090211917A1
公开(公告)日:2009-08-27
申请号:US11500931
申请日:2006-08-09
申请人: Wuu-Jyh Lin , Ting-Shien Duh , Ying-Ming Tsai , Sun-Rong Huang , Chien-Hsin Lu , Mao-Hsung Chang , Jenn-Tzong Chen
发明人: Wuu-Jyh Lin , Ting-Shien Duh , Ying-Ming Tsai , Sun-Rong Huang , Chien-Hsin Lu , Mao-Hsung Chang , Jenn-Tzong Chen
IPC分类号: C25B1/24
CPC分类号: G21G1/10 , G21G1/001 , G21G2001/0078
摘要: A radioisotope Tl-201 is produced. The process includes electroplating, irradiating, dissolving precipitating, ion exchanging, decaying and filtering. The Tl-201 obtained is a liquid having a high purity.
摘要翻译: 生产放射性同位素Tl-201。 该方法包括电镀,照射,溶解沉淀,离子交换,腐蚀和过滤。 得到的T1-201是纯度高的液体。
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公开(公告)号:US08647407B2
公开(公告)日:2014-02-11
申请号:US13352550
申请日:2012-01-18
申请人: Wuu-Jyh Lin , Chien-Hsin Lu , Jenn-Tzong Chen , Sun-Rong Hwang , Ying-Chieh Wang
发明人: Wuu-Jyh Lin , Chien-Hsin Lu , Jenn-Tzong Chen , Sun-Rong Hwang , Ying-Chieh Wang
IPC分类号: C22B58/00
CPC分类号: C22B58/00 , G21G1/001 , G21G2001/0057
摘要: The present invention provides a method for fabricating an indium(In)-111 radioactive isotope. A target of cadmium(Cd)-112 is processed through steps of dissolving with heat, absorbing, washing, desorbing and drying for obtaining the In-111 radioactive isotope. Thus, chemical separation is coordinated with the target for fabricating the In-111 radioactive isotope with high efficiency and low cost for production procedure.
摘要翻译: 本发明提供一种制造铟(In)-111放射性同位素的方法。 通过加热,吸收,洗涤,解吸和干燥的步骤来处理镉(Cd)-112的靶子,以获得In-111放射性同位素。 因此,化学分离与用于制造In-111放射性同位素的靶相配合,生产过程效率高,成本低。
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公开(公告)号:US20110214995A1
公开(公告)日:2011-09-08
申请号:US12718826
申请日:2010-03-05
申请人: Sun-Rong Huang , Ying-Ming Tsai , Jainn-Hsin Lu , Jenn-Tzong Chen , Wuu-Jyh Lin
发明人: Sun-Rong Huang , Ying-Ming Tsai , Jainn-Hsin Lu , Jenn-Tzong Chen , Wuu-Jyh Lin
IPC分类号: C25C1/22
CPC分类号: C25C1/22 , Y02P10/234
摘要: Disclosed is a method for making carrier-free radioactive isotopic gallium-67. Stable isotopic zinc-68 is turned into zinc-68 solid target by disposition or electroplating. Then, the zinc-68 solid target is subjected to a proton beam. A cyclotron is used to provide irradiation from 15 to 40 MeV. After the irradiation, the zinc-68 solid target is dissolved in concentrated acid and turned into solution that contains zinc-65, zinc-68, gallium-67 and gallium-68. High concentrated hydrochloric acid and resin are added into the solution for exchange of ions. Zinc-68 liquid and gallium-67 liquid are filtered and separated from the solution. Thus, pure gallium-67 liquid is produced. With a vaporizer, the gallium-67 liquid is vaporized and turned into radioactive isotopic gallium-67.
摘要翻译: 公开了一种制造无载体放射性同位素镓-67的方法。 通过配置或电镀,稳定的同位素锌-68变成锌-68固体靶。 然后,对锌-68固体靶进行质子束。 回旋加速器用于提供15至40MeV的照射。 照射后,将锌-68固体靶溶解在浓酸中,变成含有锌-65,锌-68,镓-67和镓-68的溶液。 将高浓度的盐酸和树脂加入溶液中以交换离子。 将锌-68液体和镓-67液体从溶液中过滤并分离。 因此,产生纯的镓-67液体。 使用蒸发器,镓-67液体被蒸发并变成放射性同位素镓-67。
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公开(公告)号:US20130104697A1
公开(公告)日:2013-05-02
申请号:US13352550
申请日:2012-01-18
申请人: Wuu-Jyh Lin , Chien-Hsin Lu , Jenn-Tzong Chen , Sun-Rong Hwang , Ying-Chieh Wang
发明人: Wuu-Jyh Lin , Chien-Hsin Lu , Jenn-Tzong Chen , Sun-Rong Hwang , Ying-Chieh Wang
IPC分类号: C22B58/00
CPC分类号: C22B58/00 , G21G1/001 , G21G2001/0057
摘要: The present invention provides a method for fabricating an indium(In)-111 radioactive isotope. A target of cadmium(Cd)-112 is processed through steps of dissolving with heat, absorbing, washing, desorbing and drying for obtaining the In-111 radioactive isotope. Thus, chemical separation is coordinated with the target for fabricating the In-111 radioactive isotope with high efficiency and low cost for production procedure.
摘要翻译: 本发明提供一种制造铟(In)-111放射性同位素的方法。 通过加热,吸收,洗涤,解吸和干燥的步骤来处理镉(Cd)-112的靶子,以获得In-111放射性同位素。 因此,化学分离与用于制造In-111放射性同位素的靶相配合,生产过程效率高,成本低。
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公开(公告)号:US20100320136A1
公开(公告)日:2010-12-23
申请号:US12621979
申请日:2009-11-19
申请人: Wuu-Jyh Lin , Jenn-Tzong Chen , Sun-Rong Huang , Ying-Ming Tsai , Jainn-Hsin Lu
发明人: Wuu-Jyh Lin , Jenn-Tzong Chen , Sun-Rong Huang , Ying-Ming Tsai , Jainn-Hsin Lu
CPC分类号: C01G15/00 , B01D61/14 , B01D61/145 , B01D61/147 , B01D61/16 , B01D2311/04 , B01D2311/16 , B01D2311/2623 , B01D2311/2673 , C01P2006/88
摘要: Disclosed is a device for separating radioisotope thallium-201. The device includes an evaporation unit for a solution vial, a first glass vial connected to a first valve and a second valve, an ion exchange column connected to a third valve, a second glass vial connected to a fourth valve and a fifth valve, a collection vial for receiving solution from the fifth valve, a product vial with a membrane filter and a vacuum unit connected to the first valve, the fourth valve and a sixth valve. This device can separate out high-concentration thallium-201 solution from which radioisotope thallium-201 can be obtained.
摘要翻译: 公开了一种用于分离放射性同位素铊-201的装置。 该装置包括用于溶液小瓶的蒸发单元,连接到第一阀和第二阀的第一玻璃小瓶,连接到第三阀的离子交换柱,连接到第四阀和第五阀的第二玻璃小瓶, 用于从第五阀接收溶液的收集瓶,具有膜过滤器的产品小瓶和连接到第一阀,第四阀和第六阀的真空单元。 该装置可以分离出可从其获得放射性同位素铊-201的高浓度铊-201溶液。
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