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Patent Agency Ranking
1.发明授权Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces 失效用于调节细胞和生物分子对疏水性表面的粘附的组成和方法公开(公告)号：US07208299B2
公开(公告)日：2007-04-24
申请号：US10748061
申请日：2003-12-30
Applicant: Karin D. Caldwell , Patrick A. Tresco , Jennifer Neff
Inventor： Karin D. Caldwell , Patrick A. Tresco , Jennifer Neff
IPC: C12N11/08 , G01N33/569 , G01N33/547
CPC classification number: C12N7/00 , C07C281/02 , C07K1/1077 , C08G65/329 , C12N5/0068 , C12N2533/30 , C12N2533/50 , C12N2533/52 , C12N2740/16051 , G01N33/54353 , Y10S436/811 , Y10S436/823 , Y10S530/816
Abstract: The present invention is directed to a composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces and hydrophobic coated surfaces. The composition is a biomolecule conjugated end-group activated polymer (EGAP). The biomolecule conjugated EGAP can be put to numerous uses including cell adhesion, cell growth, cell sorting, and other biological assays.
Abstract translation: 本发明涉及用于调节细胞和生物分子对疏水性表面和疏水性涂覆表面的粘附性的组合物和方法。 该组合物是生物分子缀合的端基活化聚合物（EGAP）。 结合EGAP的生物分子可以被广泛使用，包括细胞粘附，细胞生长，细胞分选和其他生物测定。
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2.发明授权公开(公告)号：US06670199B2
公开(公告)日：2003-12-30
申请号：US09946079
申请日：2001-09-04
Applicant: Karin D. Caldwell , Patrick A. Tresco , Jennifer Neff
Inventor： Karin D. Caldwell , Patrick A. Tresco , Jennifer Neff
IPC: G01N33547
CPC classification number: C12N7/00 , C07C281/02 , C07K1/1077 , C08G65/329 , C12N5/0068 , C12N2533/30 , C12N2533/50 , C12N2533/52 , C12N2740/16051 , G01N33/54353 , Y10S436/811 , Y10S436/823 , Y10S530/816
Abstract: The present invention is directed to a composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces and hydrophobic coated surfaces. The composition is a biomolecule conjugated end-group activated polymer (EGAP). The biomolecule conjugated EGAP can be put to numerous uses including cell adhesion, cell growth, cell sorting, and other biological assays.
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3.发明授权Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces 失效用于调节细胞和生物分子对疏水性表面的粘附的组成和方法公开(公告)号：US06284503B1
公开(公告)日：2001-09-04
申请号：US08784203
申请日：1997-01-15
Applicant: Karin D. Caldwell , Patrick A. Tresco , Jennifer Neff
Inventor： Karin D. Caldwell , Patrick A. Tresco , Jennifer Neff
IPC: C12N1108
CPC classification number: C12N7/00 , C07C281/02 , C07K1/1077 , C08G65/329 , C12N5/0068 , C12N2533/30 , C12N2533/50 , C12N2533/52 , C12N2740/16051 , G01N33/54353 , Y10S436/811 , Y10S436/823 , Y10S530/816
Abstract: The present invention is directed to a composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces and hydrophobic coated surfaces. The composition is a biomolecule conjugated end-group activated polymer (FGAP). The biomolecule conjugated EGAP can be put to numerous uses including cell adhesion, cell growth, cell sorting, and other biological assays.
Abstract translation: 本发明涉及用于调节细胞和生物分子对疏水性表面和疏水性涂覆表面的粘附性的组合物和方法。 该组合物是生物分子共轭的端基活化聚合物（FGAP）。 结合EGAP的生物分子可以被广泛使用，包括细胞粘附，细胞生长，细胞分选和其他生物测定。
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公开(公告)号：US20050106208A1
公开(公告)日：2005-05-19
申请号：US10969541
申请日：2004-10-20
Applicant: Jennifer Neff , Karin Caldwell , Jonas Andersson , Bo Nilsson , Kristina Nilsson-Ekdahl
Inventor： Jennifer Neff , Karin Caldwell , Jonas Andersson , Bo Nilsson , Kristina Nilsson-Ekdahl
CPC classification number: A61L27/54 , A61K47/56 , A61K47/60 , A61L27/34 , A61L2300/25 , A61L2300/252 , A61L2300/258 , A61L2300/604 , C08L71/02
Abstract: Elutable coatings comprising protein resistant components and bioactive agent on medical devices are disclosed. The elutable coatings comprise labile linkers that can be cleaved under controlled conditions.
Abstract translation: 公开了包含蛋白质抗性组分和在医疗装置上的生物活性剂的可洗涤涂层。 可洗涤涂层包含可在受控条件下裂解的不稳定接头。
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公开(公告)号：US20050244456A1
公开(公告)日：2005-11-03
申请号：US11111468
申请日：2005-04-21
Applicant: Bo Nilsson , Jonas Andersson , Karin Caldwell , Jennifer Neff , Kristina Nilsson-Ekdahl , Wade Takeguchi
Inventor： Bo Nilsson , Jonas Andersson , Karin Caldwell , Jennifer Neff , Kristina Nilsson-Ekdahl , Wade Takeguchi
CPC classification number: A61L33/0017 , A61L27/34 , A61L29/085 , A61L31/10 , C08L71/02
Abstract: Coatings comprising protein resistant components and therapeutic components on medical devices are disclosed. The coatings act to down-regulate complement activation. Medical devices can be coated with these coatings to prevent side effects and improve patency.
Abstract translation: 公开了在医疗装置上包含蛋白质抗性组分和治疗成分的涂层。 涂层用于下调补体活化。 医疗器械可以涂上这些涂层，以防止副作用并改善通畅。
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