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公开(公告)号:US07070800B2
公开(公告)日:2006-07-04
申请号:US09975418
申请日:2001-10-11
CPC分类号: A61K9/0075 , A61K9/14 , A61K31/439
摘要: The invention relates to powdered preparations containing tiotropium for inhalation, processes for preparing them as well as their use in preparing a pharmaceutical composition for the treatment of respiratory complaints, particularly for the treatment of COPD (chronic obstructive pulmonary disease) and asthma.
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公开(公告)号:US20060039868A1
公开(公告)日:2006-02-23
申请号:US11254573
申请日:2005-10-20
IPC分类号: A61L9/04 , A61K9/14 , A61K31/4745
CPC分类号: A61K9/0075 , A61K9/14 , A61K31/439
摘要: The invention relates to powdered preparations containing tiotropium for inhalation, processes for preparing them as well as their use in preparing a pharmaceutical composition for the treatment of respiratory complaints, particularly for the treatment of COPD (chronic obstructive pulmonary disease) and asthma.
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公开(公告)号:US06905239B2
公开(公告)日:2005-06-14
申请号:US10226062
申请日:2002-08-22
申请人: Georg Boeck , Michael Walz
发明人: Georg Boeck , Michael Walz
CPC分类号: A61K9/0075 , A61K9/1694
摘要: The invention relates to a new process for producing powdered preparations for inhalation wherein a substance having a smaller particle size distribution is metered continuously through a suitable feed device onto a moving bed of a powdered substance having a larger particle size distribution.
摘要翻译: 本发明涉及一种用于生产粉末吸入制剂的新方法,其中具有较小粒度分布的物质通过合适的进料装置连续地计量到具有较大粒度分布的粉末物质的移动床上。
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公开(公告)号:USRE38912E1
公开(公告)日:2005-12-06
申请号:US10766748
申请日:2004-01-28
申请人: Michael Walz , Georg Boeck
发明人: Michael Walz , Georg Boeck
IPC分类号: C07D451/12 , A61K9/00 , A61K9/14 , A61K9/51 , A61K9/72 , A61K31/439 , A61K31/46 , A61K47/02 , A61K47/26 , A61P11/00 , A61P11/06 , A61P43/00 , A61F13/02 , A61K9/16 , A61L9/04
CPC分类号: A61K9/0075 , A61K9/14 , A61K9/145 , A61K31/439
摘要: The invention relates to a new process for producing powdered preparations for inhalation.
摘要翻译: 本发明涉及一种生产用于吸入的粉末制剂的新方法。
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公开(公告)号:US20070231272A1
公开(公告)日:2007-10-04
申请号:US11762252
申请日:2007-06-13
申请人: Georg Boeck , Michael Walz
发明人: Georg Boeck , Michael Walz
IPC分类号: A61K9/14
CPC分类号: A61K9/0075 , A61K31/46
摘要: The invention relates to a new process for producing powdered preparations for inhalation comprising a substance having a smaller particle size distribution and a substance having a larger particle size distribution, wherein a substance having a smaller particle size distribution and a substance having a larger particle size distribution are continuously metered into a suitable mixing container such that the quotient N of the delivery speed for the metering of the substance having the smaller particle size distribution and the delivery speed for the metering of the substance having the larger particle size distribution is at least as great as the quotient M of the total mass of the substance having the smaller particle size distribution and the total mass of the substance having the larger particle size distribution.
摘要翻译: 本发明涉及一种用于生产粉末吸入制剂的新方法,其包括具有较小粒度分布的物质和具有较大粒度分布的物质,其中具有较小粒度分布的物质和具有较大粒度分布的物质 连续地计量到合适的混合容器中,使得具有较小粒度分布的物质计量的输送速度的商N和具有较大粒度分布的物质计量的输送速度至少为 作为具有较小粒度分布的物质和具有较大粒度分布的物质的总质量的总质量的商M。
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公开(公告)号:US07244414B2
公开(公告)日:2007-07-17
申请号:US10225781
申请日:2002-08-22
申请人: Georg Boeck , Michael Walz
发明人: Georg Boeck , Michael Walz
CPC分类号: A61K9/0075 , A61K31/46
摘要: The invention relates to a new process for producing powdered preparations for inhalation comprising a substance having a smaller particle size distribution and a substance having a larger particle size distribution, wherein a substance having a smaller particle size distribution and a substance having a larger particle size distribution are continuously metered into a suitable mixing container such that the quotient N of the delivery speed for the metering of the substance having the smaller particle size distribution and the delivery speed for the metering of the substance having the larger particle size distribution is at least as great as the quotient M of the total mass of the substance having the smaller particle size distribution and the total mass of the substance having the larger particle size distribution.
摘要翻译: 本发明涉及一种用于生产粉末吸入制剂的新方法,其包括具有较小粒度分布的物质和具有较大粒度分布的物质,其中具有较小粒度分布的物质和具有较大粒度分布的物质 连续地计量到合适的混合容器中,使得具有较小粒度分布的物质计量的输送速度的商N和具有较大粒度分布的物质计量的输送速度至少为 作为具有较小粒度分布的物质和具有较大粒度分布的物质的总质量的总质量的商M。
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公开(公告)号:US06585959B2
公开(公告)日:2003-07-01
申请号:US09977911
申请日:2001-10-11
申请人: Michael Walz , Georg Boeck
发明人: Michael Walz , Georg Boeck
IPC分类号: A61K914
CPC分类号: A61K9/0075 , A61K9/14 , A61K9/145 , A61K31/439
摘要: The invention relates to a new process for producing powdered preparations for inhalation.
摘要翻译: 本发明涉及一种生产用于吸入的粉末制剂的新方法。
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公开(公告)号:US07870856B2
公开(公告)日:2011-01-18
申请号:US11733399
申请日:2007-04-10
申请人: Georg Boeck
发明人: Georg Boeck
IPC分类号: A61M11/00
CPC分类号: A61M15/0028 , A61M11/003 , A61M15/0041 , A61M2205/273 , A61M2209/06
摘要: An inhaler for administering a medicament in the form of inhalable substances, formulations or mixtures of substances comprises a housing (1) having an inner cavity for holding the medicament, which is coupled to a mouthpiece (2). The housing (1) is rigidly connected to the mouthpiece (2).
摘要翻译: 用于施用可吸入物质,制剂或物质混合物形式的药物的吸入器包括具有用于保持药物的内腔的壳体(1),其连接到接口(2)。 壳体(1)刚性地连接到接口管(2)。
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公开(公告)号:US07823584B2
公开(公告)日:2010-11-02
申请号:US11466941
申请日:2006-08-24
申请人: Johannes Geser , Burkhard P. Metzger , Christian Goldberg , Michael Schyra , Ralf Thoemmes , Birgit Westmeier , Guido Schmiedel , Hubert Kunze , Georg Boeck
发明人: Johannes Geser , Burkhard P. Metzger , Christian Goldberg , Michael Schyra , Ralf Thoemmes , Birgit Westmeier , Guido Schmiedel , Hubert Kunze , Georg Boeck
IPC分类号: B05B3/02 , B05B7/30 , B05B1/32 , A61M11/00 , A61M5/30 , B67D7/22 , B67D7/84 , B67D7/08 , B67B1/00
CPC分类号: A61M15/0065 , A61M11/007 , A61M15/0026 , A61M15/0036 , A61M15/004 , A61M15/0066 , A61M15/0073 , A61M15/0076 , A61M15/0078 , A61M15/0081 , A61M2202/064 , A61M2205/273 , A61M2205/6045 , B05B11/0054 , B05B11/308 , B05B11/3091 , G06M3/02
摘要: An atomizer for a fluid, in particular, a fluid for medical aerosol therapy. In order to allow simplified operation and improved safety in use, the atomizer has a counter device for counting the number of operations of the atomizer and the number of containers inserted. The atomizer is locked against further operation and/or against removal of the current container or insertion of a new container, if a certain number of operations of the atomizer and/or a certain number of containers inserted has/have been reached or exceeded.
摘要翻译: 用于流体的雾化器,特别是用于医疗气溶胶治疗的流体。 为了简化操作和提高使用安全性,雾化器具有用于计数雾化器的操作次数和插入的容器数量的计数装置。 如果雾化器的某些数量的操作和/或一定数量的容器被插入或已经达到或超过,则雾化器被锁定以防止进一步的操作和/或不去除当前的容器或插入新的容器。
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10.
公开(公告)号:US20050101625A1
公开(公告)日:2005-05-12
申请号:US10935502
申请日:2004-09-07
申请人: Georg Boeck , Friedrich Schmidt
发明人: Georg Boeck , Friedrich Schmidt
IPC分类号: A61K9/00 , A61K31/46 , A61K31/4745 , A61P43/00
CPC分类号: A61K9/0078 , A61K31/46
摘要: A pharmaceutical composition comprising: (a) an active substance consisting of a compound of formula 1 wherein X− is an anion; (b) ethanol or a mixture of ethanol and water; (c) a pharmacologically acceptable acid.
摘要翻译: 一种药物组合物,其包含:(a)由式1化合物组成的活性物质,其中X为 - 阴离子; (b)乙醇或乙醇和水的混合物; (c)药理学上可接受的酸。
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