AEROSOL FORMULATION FOR INHALATION CONTAINING AN ANTICHOLINERGIC AGENT
    4.
    发明申请
    AEROSOL FORMULATION FOR INHALATION CONTAINING AN ANTICHOLINERGIC AGENT 审中-公开
    用于吸入含有抗焦虑剂的气溶胶制剂

    公开(公告)号:US20090221626A1

    公开(公告)日:2009-09-03

    申请号:US12094196

    申请日:2006-11-13

    CPC classification number: A61K9/0078 A61K31/46 A61K47/12

    Abstract: The invention relates to specific aqueous aerosol formulations that are devoid of propellant, containing one or more anticholinergic agents of formula (1), in which X represents an anion, and containing at least one pharmacologically compatible organic acid and optionally additional pharmacologically compatible adjuvants and/or complexing agents. The cation of formula (1′) is contained in the preparation at a concentration of between 411 and 460.32 mg per 100 ml of medicament preparation.

    Abstract translation: 本发明涉及不含推进剂的特定水性气溶胶制剂,其含有一种或多种式(1)的抗胆碱能剂,其中X表示阴离子,并含有至少一种药理学上相容的有机酸和任选的其它药学上相容的佐剂和/ 或络合剂。 式(1')的阳离子在制剂中以每100ml药物制剂的浓度为411-460.32mg含有。

    HFC SOLUTION FORMULATIONS CONTAINING SALBUTAMOL HYDROCHLORIDE OR SALBUTAMOL CITRATE
    7.
    发明申请
    HFC SOLUTION FORMULATIONS CONTAINING SALBUTAMOL HYDROCHLORIDE OR SALBUTAMOL CITRATE 审中-公开
    含有盐酸氢氯化物或沙丁胺醇柠檬酸盐的HFC溶液制剂

    公开(公告)号:US20070041911A1

    公开(公告)日:2007-02-22

    申请号:US11463477

    申请日:2006-08-09

    CPC classification number: C07C215/60 A61K9/008 A61K31/137 C07C59/265

    Abstract: This invention relates to stabilized aerosol solution formulations containing acid addition salts of salbutamol, which are suitable for administration by metered dose inhalers (MDIs). More particularly, this invention relates to solution formulations containing one of the aforementioned salts of salbutamol, preferably salbutamol hydrochloride or salbutamol citrate, more preferably one of the two before mentioned salts in combination with one or more additional pharmacologically active substances, together with an environmentally safe hydrofluorocarbon (HFC) as a propellant, a co-solvent, preferably an organic compound as a co-solvent, and either an inorganic acid or an organic acid.

    Abstract translation: 本发明涉及含有沙丁胺醇酸加成盐的稳定化气溶胶制剂,其适用于计量吸入器(MDI)的给药。 更具体地说,本发明涉及含有上述沙丁胺醇盐之一,优选盐酸沙丁胺醇或沙丁胺醇柠檬酸盐的溶液制剂,更优选两种上述盐中的一种与一种或多种另外的药理学活性物质组合,以及环境安全 作为推进剂的氢氟烃(HFC),共溶剂,优选作为助溶剂的有机化合物,以及无机酸或有机酸。

    Fragrance composition comprising at least one ionic liquid, method for production and use thereof
    8.
    发明申请
    Fragrance composition comprising at least one ionic liquid, method for production and use thereof 审中-公开
    包含至少一种离子液体的香料组合物,其制备方法和用途

    公开(公告)号:US20060166856A1

    公开(公告)日:2006-07-27

    申请号:US10529947

    申请日:2003-10-08

    CPC classification number: C11D3/50 A61K8/4946 A61Q13/00 C11D1/60 C11D1/62 C11D3/28

    Abstract: The invention relates to a fragrance composition which has, as fixative, at least one ionic liquid, and to the preparation and use thereof. The fragrance compositions according to the invention are advantageous since the ionic liquid, being a polar solvent which has as it were no vapor pressure, can delay the evaporation of the base scent components in a targeted manner. The large choice of ionic liquids allows the rate of evaporation of the scent components to be adjusted precisely. Since the polarity of the ionic liquids can be varied by means of the structure of the cations and/or anions within wide ranges, the ionic liquids used as fixative can be matched precisely to the chemicophysical and/or olfactory requirements of the scent component.

    Abstract translation: 本发明涉及一种具有至少一种离子液体作为固定剂的香料组合物及其制备和用途。 根据本发明的香料组合物是有利的,因为作为非蒸气压的极性溶剂的离子液体可以以目标方式延迟基础气味组分的蒸发。 离子液体的大量选择允许气味组分的蒸发速率被精确调节。 由于离子液体的极性可以通过在宽范围内的阳离子和/或阴离子的结构而变化,所以用作固定剂的离子液体可以精确地与香味组分的化学物理和/或嗅觉要求相匹配。

    Crop protection emulsifiable concentrate containing defoaming agents
    10.
    发明授权
    Crop protection emulsifiable concentrate containing defoaming agents 有权
    作物保护含有消泡剂的乳油

    公开(公告)号:US06444618B1

    公开(公告)日:2002-09-03

    申请号:US09491831

    申请日:2000-01-26

    Abstract: The novel emulsifiable concentrate (EC) formulation comprising at least one pesticidal crop protection active compound, at least one non-polar organic solvent, optionally, at least one polar aprotic cosolvent, an emulsifying surfactant system enabling an oil-in-water emulsion to be formed when the formulation is added to water, and at least one defoaming or foam breaking agent selected from the group consisting of perfluoroalkylphosphonic acids, perfluoroalkylphosphinic acids and perfluoroaliphatic polymeric esters is useful for combating pests or diseases caused by pests at a locus by treating the locus with a composition obtained from emulsifying the EC in water.

    Abstract translation: 包含至少一种杀虫作物保护活性化合物,至少一种非极性有机溶剂,任选的至少一种极性非质子共溶剂的新型可乳化浓缩物(EC)制剂,使水包油乳液成为 在将配方添加到水中时形成,并且至少一种选自全氟烷基膦酸,全氟烷基次膦酸和全氟脂肪族聚合酯的消泡剂或泡沫破坏剂可用于通过处理所述基因座来对抗由害虫引起的害虫或疾病 具有通过在水中乳化EC获得的组合物。

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