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1.发明授权公开(公告)号：US07354706B2
公开(公告)日：2008-04-08
申请号：US11372485
申请日：2006-03-09
申请人： Kathy L. Rowlen , John W. Birks , Christopher Bowman , Hadley Sikes , Ryan Hansen , Robert Kuchta
发明人： Kathy L. Rowlen , John W. Birks , Christopher Bowman , Hadley Sikes , Ryan Hansen , Robert Kuchta
CPC分类号： C12Q1/6816 , C12Q2565/401
摘要： The invention provides methods to detect molecular recognition events. The invention also provides methods to detect the presence of or identify a target species based on its interaction with one or more probe species. The methods of the invention are based on amplification of the signal due to each molecular recognition event. The amplification is achieved through photopolymerization, with the polymer formed being associated with the molecular recognition event. In an embodiment, a fluorescent polymer, a magnetic polymer, a radioactive polymer or an electrically conducting polymer can form the basis of detection and amplification. In another embodiment, a polymer gel swollen with a fluorescent solution, a magnetic solution, a radioactive solution or an electrically conducting solution can form the basis of detection and amplification. In another embodiment, sufficient polymer forms to be detectable by visual inspection.
摘要翻译： 本发明提供检测分子识别事件的方法。 本发明还提供了基于其与一种或多种探针物种的相互作用来检测靶物种的存在或鉴定目的物种的方法。 本发明的方法基于由于每个分子识别事件引起的信号的放大。 通过光聚合实现扩增，形成的聚合物与分子识别事件相关联。 在一个实施方案中，荧光聚合物，磁性聚合物，放射性聚合物或导电聚合物可以形成检测和扩增的基础。 在另一个实施方案中，用荧光溶液，磁性溶液，放射性溶液或导电溶液溶胀的聚合物凝胶可以形成检测和扩增的基础。 在另一个实施方案中，足够的聚合物形式可通过目视检查来检测。
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2.发明申请公开(公告)号：US20060286570A1
公开(公告)日：2006-12-21
申请号：US11372485
申请日：2006-03-09
申请人： Kathy Rowlen , John Birks , Christopher Bowman , Hadley Sikes , Ryan Hansen , Robert Kuchta
发明人： Kathy Rowlen , John Birks , Christopher Bowman , Hadley Sikes , Ryan Hansen , Robert Kuchta
CPC分类号： C12Q1/6816 , C12Q2565/401
摘要： The invention provides methods to detect molecular recognition events. The invention also provides methods to detect the presence of or identify a target species based on its interaction with one or more probe species. The methods of the invention are based on amplification of the signal due to each molecular recognition event. The amplification is achieved through photopolymerization, with the polymer formed being associated with the molecular recognition event. In an embodiment, a fluorescent polymer, a magnetic polymer, a radioactive polymer or an electrically conducting polymer can form the basis of detection and amplification. In another embodiment, a polymer gel swollen with a fluorescent solution, a magnetic solution, a radioactive solution or an electrically conducting solution can form the basis of detection and amplification. In another embodiment, sufficient polymer forms to be detectable by visual inspection.
摘要翻译： 本发明提供检测分子识别事件的方法。 本发明还提供了基于其与一种或多种探针物种的相互作用来检测靶物种的存在或鉴定目的物种的方法。 本发明的方法基于由于每个分子识别事件引起的信号的放大。 通过光聚合实现扩增，形成的聚合物与分子识别事件相关联。 在一个实施方案中，荧光聚合物，磁性聚合物，放射性聚合物或导电聚合物可以形成检测和扩增的基础。 在另一个实施方案中，用荧光溶液，磁性溶液，放射性溶液或导电溶液溶胀的聚合物凝胶可以形成检测和扩增的基础。 在另一个实施方案中，足够的聚合物形式可通过目视检查来检测。
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3.发明授权公开(公告)号：US08652778B2
公开(公告)日：2014-02-18
申请号：US13082814
申请日：2011-04-08
CPC分类号： C12Q1/6816 , C12Q2565/401 , C12Q2523/313
摘要： The invention provides methods to detect molecular recognition events. The invention also provides methods to detect the presence of or identify a target species based on its interaction with one or more probe species. The methods of the invention are based on amplification of the signal due to each molecular recognition event. The amplification is achieved through photopolymerization, with the polymer formed being associated with the molecular recognition event. In one aspect, a fluorescent polymer, a magnetic polymer, a radioactive polymer or an electrically conducting polymer can form the basis of detection and amplification. In another aspect, a polymer gel swollen with a fluorescent solution, a magnetic solution, a radioactive solution or an electrically conducting solution can form the basis of detection and amplification. In another aspect, detectable particles can be included in the polymer formed. In another aspect, sufficient polymer forms to be detectable by visual inspection.
摘要翻译： 本发明提供检测分子识别事件的方法。 本发明还提供了基于其与一种或多种探针物种的相互作用来检测靶物种的存在或鉴定目的物种的方法。 本发明的方法基于由于每个分子识别事件引起的信号的放大。 通过光聚合实现扩增，形成的聚合物与分子识别事件相关联。 一方面，荧光聚合物，磁性聚合物，放射性聚合物或导电聚合物可以形成检测和扩增的基础。 另一方面，用荧光溶液，磁性溶液，放射性溶液或导电溶液溶胀的聚合物凝胶可以形成检测和扩增的基础。 在另一方面，所形成的聚合物中可以包括可检测的颗粒。 另一方面，足够的聚合物形式可通过视觉检查来检测。
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4.发明申请公开(公告)号：US20110251092A1
公开(公告)日：2011-10-13
申请号：US13082814
申请日：2011-04-08
CPC分类号： C12Q1/6816 , C12Q2565/401 , C12Q2523/313
摘要： The invention provides methods to detect molecular recognition events. The invention also provides methods to detect the presence of or identify a target species based on its interaction with one or more probe species. The methods of the invention are based on amplification of the signal due to each molecular recognition event. The amplification is achieved through photopolymerization, with the polymer formed being associated with the molecular recognition event. In one aspect, a fluorescent polymer, a magnetic polymer, a radioactive polymer or an electrically conducting polymer can form the basis of detection and amplification. In another aspect, a polymer gel swollen with a fluorescent solution, a magnetic solution, a radioactive solution or an electrically conducting solution can form the basis of detection and amplification. In another aspect, detectable particles can be included in the polymer formed. In another aspect, sufficient polymer forms to be detectable by visual inspection.
摘要翻译： 本发明提供检测分子识别事件的方法。 本发明还提供了基于其与一种或多种探针物种的相互作用来检测靶物种的存在或鉴定目的物种的方法。 本发明的方法基于由于每个分子识别事件引起的信号的放大。 通过光聚合实现扩增，形成的聚合物与分子识别事件相关联。 一方面，荧光聚合物，磁性聚合物，放射性聚合物或导电聚合物可以形成检测和扩增的基础。 另一方面，用荧光溶液，磁性溶液，放射性溶液或导电溶液溶胀的聚合物凝胶可以形成检测和扩增的基础。 在另一方面，所形成的聚合物中可以包括可检测的颗粒。 另一方面，足够的聚合物形式可通过视觉检查来检测。
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5.发明申请Use of Photopolymerization for Amplification and Detection of a Molecular Recognition Event 审中-公开使用光聚合扩增和检测分子识别事件公开(公告)号：US20090163375A1
公开(公告)日：2009-06-25
申请号：US12099560
申请日：2008-04-08
IPC分类号： C40B30/04
CPC分类号： C12Q1/6816 , C12Q2565/401 , C12Q2523/313
摘要： The invention provides methods to detect molecular recognition events. The invention also provides methods to detect the presence of or identify a target species based on its interaction with one or more probe species. The methods of the invention are based on amplification of the signal due to each molecular recognition event. The amplification is achieved through photopolymerization, with the polymer formed being associated with the molecular recognition event. In one aspect, a fluorescent polymer, a magnetic polymer, a radioactive polymer or an electrically conducting polymer can form the basis of detection and amplification. In another aspect, a polymer gel swollen with a fluorescent solution, a magnetic solution, a radioactive solution or an electrically conducting solution can form the basis of detection and amplification. In another aspect, detectable particles can be included in the polymer formed. In another aspect, sufficient polymer forms to be detectable by visual inspection.
摘要翻译： 本发明提供检测分子识别事件的方法。 本发明还提供了基于其与一种或多种探针物种的相互作用来检测靶物种的存在或鉴定目的物种的方法。 本发明的方法基于由于每个分子识别事件引起的信号的放大。 通过光聚合实现扩增，形成的聚合物与分子识别事件相关联。 一方面，荧光聚合物，磁性聚合物，放射性聚合物或导电聚合物可以形成检测和扩增的基础。 另一方面，用荧光溶液，磁性溶液，放射性溶液或导电溶液溶胀的聚合物凝胶可以形成检测和扩增的基础。 在另一方面，所形成的聚合物中可以包括可检测的颗粒。 另一方面，足够的聚合物形式可通过视觉检查来检测。
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公开(公告)号：US20070000849A1
公开(公告)日：2007-01-04
申请号：US11271404
申请日：2005-11-10
申请人： Robert Lutz , Matthew Mueller , Chad Gloege , Neil Burghardt , Harvey Mehlum , Brett Wendler , Russell Neyens , Nathan Nearman , Mark Dennis , Ryan Hansen
发明人： Robert Lutz , Matthew Mueller , Chad Gloege , Neil Burghardt , Harvey Mehlum , Brett Wendler , Russell Neyens , Nathan Nearman , Mark Dennis , Ryan Hansen
IPC分类号： A47F7/00
CPC分类号： G09F9/33 , G09F9/3026
摘要： A modular display system having individual stackable electronic display panels of convenient and portable size and mounting structures for the support thereof where the stackable electronic display panels mutually juxtapose, mate, and robustly and mutually and adjustably secure together by the use of connector plates at the top of stackable electronic display panels interfacing with interlocking lower connector assemblies and lower connector plate receptors at the bottom of an overhead vertically situated stackable electronic display panel and by interfacing of latches and cams of latch keeper assemblies at the sides of horizontally situated stackable electronic display panels to form a large electronic sign display. Spring-loaded slide pin assemblies foster rapid and secure connection between vertically situated stackable electronic display panels. Adjustment features are also incorporated to align each stackable electronic display panel.
摘要翻译： 一种模块化显示系统，具有方便和便携的尺寸和安装结构的单个可堆叠电子显示面板，用于支撑可堆叠电子显示面板，其中堆叠式电子显示面板通过在顶部使用连接器板而互相并排，相互并联并且可调节地固定在一起 可叠置的电子显示面板与互锁的下连接器组件和下部连接器板接收器连接在顶部垂直定位的可堆叠的电子显示面板的底部，并且通过将水平定位的可堆叠的电子显示面板的侧面的闩锁保持器组件的闩锁和凸轮的接口连接到 形成一个大型电子标志显示。 弹簧加载的滑动销组件可以在垂直定位的可堆叠电子显示面板之间建立快速和安全的连接。 还结合了调整特征以对准每个可堆叠的电子显示面板。
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公开(公告)号：US20050022354A1
公开(公告)日：2005-02-03
申请号：US10604561
申请日：2003-07-30
申请人： Gerald Dykstra , Gregory Bleeker , Kent Deemter , Ryan Hansen , Robert Humphrey , Thomas Walkons
发明人： Gerald Dykstra , Gregory Bleeker , Kent Deemter , Ryan Hansen , Robert Humphrey , Thomas Walkons
CPC分类号： B23P19/041 , Y10S83/943 , Y10T29/49821 , Y10T29/5139 , Y10T29/53317 , Y10T29/5383
摘要： A method and apparatus for at least partially disassembling a pallet, the pallet having a plurality of deck board support interfaces, includes providing at least one cutting device that is positionable at any one of the board support interfaces and selectively positioning the at least one cutting device adjacent a particular board support interface of the pallet. The particular board support interface is cut with the at least one cutting device.
摘要翻译： 一种用于至少部分地拆卸托盘的方法和装置，所述托盘具有多个甲板板支撑接口，包括提供至少一个切割装置，所述至少一个切割装置可定位在所述板支撑接口中的任一个处，并且选择性地定位所述至少一个切割装置 毗邻托盘的特定板支撑界面。 用至少一个切割装置切割特定的板支撑界面。
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公开(公告)号：US10661908B2
公开(公告)日：2020-05-26
申请号：US15724995
申请日：2017-10-04
申请人： Jonathan B. Boreyko , Saurabh Nath , Caitlin Bisbano , Grady J. Iliff , Ryan Hansen , C. Patrick Collier
发明人： Jonathan B. Boreyko , Saurabh Nath , Caitlin Bisbano , Grady J. Iliff , Ryan Hansen , C. Patrick Collier
摘要： A method and device for reducing ice and frost on a surface comprising a wettable pattern on a surface. The pattern is wetted with water which is frozen into ice to create overlapping hygroscopic that cover the surface.
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公开(公告)号：US07306500B1
公开(公告)日：2007-12-11
申请号：US11000669
申请日：2004-11-30
申请人： Lysle Spangler , Ryan Hansen
发明人： Lysle Spangler , Ryan Hansen
IPC分类号： B63H21/34
CPC分类号： B63H21/32 , B63H21/34 , F01N13/08 , F01N2450/26 , F01N2590/02
摘要： The present invention is a device which redirects motor exhaust fumes a distance away from a boat. This device can be applied to a boat's propulsion motor or to its generator for purposes of preventing carbon monoxide poisoning of a boat's passengers. The device includes an adaptor for attaching to a boat motor exhaust port and an elongate extension hose attached to the adaptor. The extension hose is made buoyant through use of a plurality of flotation collars disposed along the length of the hose. An extension rod is inserted into the collars to keep the hose rigid and the distal exhaust end of the hose directed away from a boat to which the device is attached.
摘要翻译： 本发明是一种将电动机废气重新排列离船的距离的装置。 该装置可以应用于船的推进马达或其发电机，以防止一小时乘客的一氧化碳中毒。 该装置包括用于附接到船用电机排气口的适配器和连接到适配器的细长延伸软管。 延伸软管通过使用沿着软管的长度设置的多个浮选环制成浮力。 将延伸杆插入套环中以保持软管刚性并且软管的远端排气端远离装置所附接的船。
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10.发明申请Clinical application utilizing genetic data for effective medication management 审中-公开临床应用利用遗传数据进行有效的药物治疗公开(公告)号：US20130029862A1
公开(公告)日：2013-01-31
申请号：US13488397
申请日：2012-06-04
申请人： Gareth Davies , Ryan Hansen
发明人： Gareth Davies , Ryan Hansen
CPC分类号： A61K31/135 , A61K31/137 , A61K31/445
摘要： The present disclosure relates a predictive method, based on a subject's genetic profile, which defines variability in a specific disease or condition to determine medication response, including determining select VNTR and SNP occurrence combinations which are associated with specific responses to medications, kits and DNA chips/arrays containing such combinations so as to effectuate better medication management.
摘要翻译： 本公开涉及基于受试者遗传图谱的预测方法，该方法定义特定疾病或病症中的变异性以确定药物应答，包括确定与药物，试剂盒和DNA芯片的特异性反应相关的选择性VNTR和SNP发生组合 /包含这些组合的阵列，以便实现更好的药物管理。
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