摘要:
A halocyanoacetamide compound having the formula: ##STR1## wherein X is a halogen such as Cl, F, Br and I; Y represents a halogen such as chlorine, fluorine, bromine and iodine or hydrogen atom; andR represents a hydrogen atom or a lower alkyl group containing from 1 to 8 carbon atoms, is stabilized with an organic carboxylic acid or a diol.
摘要:
A halocyanoacetamide compound having the formula: ##STR1## wherein X is a halogen such as Cl, F, Br and I; Y represents a halogen such as chlorine, fluorine, bromine and iodine or hydrogen atom; andR represents a hydrogen atom or a lower alkyl group containing from 1 to 8 carbon atoms, is stabilized with an organic carboxylic acid or a diol.
摘要:
The invention provides an industrial method for producing a spiroaminopyrrolidone derivative, which is an intermediate for producing a quinolone antibacterial agent.The invention provides a method for producing a compound represented by formula (2): (wherein n is an integer of 2 to 5; R1 represents a (substituted) alkyl group or a (substituted) aryl group; and R2 represents a (substituted) alkoxycarbonyl group, a (substituted) aralkyloxycarbonyl group, a (substituted) aliphatic acyl group, or a (substituted) aromatic acyl group), which includes treating a compound represented by formula (1): (wherein n, R1, and R2 are the same as defined above; and R3 represents a hydrogen atom, a (substituted) alkyl group, or a (substituted) aralkyl group) under a hydrogen gas atmosphere in the presence of a metallic catalyst.
摘要翻译:本发明提供一种生产螺环氨基吡咯烷酮衍生物的工业方法,其是用于生产喹诺酮抗菌剂的中间体。 本发明提供一种制备由式(2)表示的化合物的方法:(其中n为2至5的整数; R 1表示(取代的)烷基或(取代的)芳基; R 2表示(取代的) 烷氧基羰基,(取代的)芳烷氧基羰基,(取代的)脂族酰基或(取代的)芳族酰基),其包括处理由式(1)表示的化合物:其中n,R1和R2是 在氢气气氛下,在金属催化剂的存在下,R 3表示氢原子,(取代的)烷基或(取代的)芳烷基)。
摘要:
Provided are a technique for position-selectively introducing an amino group into a difluorobenzoic acid, a novel process for producing a quinolonecarboxylic acid derivative serving as an antibacterial agent, and intermediates in the production. The process comprises treating a compound represented by formula (6): with a base in a water-containing solvent. The intermediates are represented by formula (6):
摘要:
A process for producing an optically active compound represented by formula (4) or a salt thereof: the process including reacting a cyclization reagent with an optically active compound represented by formula (3) or its salt: optionally in the presence of a Lewis acid, to form the compound of formula (4) or its salt, wherein, in the compounds of formula (3) and formula (4) and their salts, R1 is a protecting group, and wherein the cyclization reagent is prepared from a titanium (IV) reagent and an alkylmetal compound.
摘要:
A plasma processing apparatus includes: a processing container capable of maintaining an atmosphere having a pressure lower than atmospheric pressure; an evacuation unit reducing a pressure of an interior of the processing container; a gas introduction unit introducing a process gas to the interior of the processing container; a microwave introduction unit introducing a microwave to the interior of the processing container; and a lifter pin ascendably and descendably inserted through a placement platform provided in the interior of the processing container, an end surface of the lifter pin supporting an object to be processed, the object to be processed being supported by the lifter pin at a first position proximal to an upper surface of the placement platform when the microwave is introduced and plasma is ignited, the object to be processed being supported by the lifter pin at a second position after the plasma ignition, the second position being more distal to the placement platform than the first position.
摘要:
The invention provides an industrial method for producing a spiroaminopyrrolidone derivative, which is an intermediate for producing a quinolone antibacterial agent.
摘要:
The invention provides an industrial method for producing a spiroaminopyrrolidone derivative, which is an intermediate for producing a quinolone antibacterial agent. Specifically, the invention provides a method for producing a compound of formula (2): wherein n is an integer of 2 to 5; R1 is a (substituted) alkyl group or a (substituted) aryl group; and R2 represents a (substituted) alkoxycarbonyl group, a (substituted) aralkyloxycarbonyl group, a (substituted) aliphatic acyl group, or a (substituted) aromatic acyl group).
摘要:
There is provided an air amount computing unit, and a fuel control unit, of an internal combustion engine that calculates a cylinder flow-in air amount during a transient state without response delay and so as not to have any inflection point in changes of flow rate and that allows a desirable air-fuel ratio to be kept. The air amount computing unit has air amount detecting means for detecting an air amount passing through an intake throttle section of the internal combustion engine, air amount computing means for obtaining a calculated value of the air amount passing through the intake throttle section from an throttle opening angle, means for obtaining an air amount flowing into a cylinder of the internal combustion engine by excluding an air amount filled into an intake manifold by filtering by a difference between a value of the air amount passing through the intake throttle section of this time and a previous filtering value, a first filter based on the air amount detected by the air amount detecting means, a second filter based on the calculated value of the air amount obtained by the air amount computing means, selecting means for selecting an input value and a previous output value of the first filter when the internal combustion engine is in a static state and selecting an input value and a previous output value of the second filter when the internal combustion engine is in a transient state and a third filter for inputting a selected value selected by said selecting means, wherein the output of the third filter is determined to be an air amount flowing into the cylinder.