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153 条记录 (耗时 0.037 秒)

    Methods of preparing lymphocytes that express interleukin-2 and their use in the treatment of cancer
    1.
    发明授权
    Methods of preparing lymphocytes that express interleukin-2 and their use in the treatment of cancer 有权
    制备表达白细胞介素-2的淋巴细胞的方法及其在治疗癌症中的应用

    公开(公告)号：US07381405B2

    公开(公告)日：2008-06-03

    申请号：US10531145

    申请日：2002-10-15

    申请人： Ke Liu ,  Steven A. Rosenberg

    发明人： Ke Liu ,  Steven A. Rosenberg

    IPC分类号： A01N63/00 ,  A61K39/00 ,  C12N15/00 ,  C12N15/63 ,  C07H21/04

    CPC分类号： A61K39/0011 ,  A61K2035/124 ,  A61K2039/5156 ,  A61K2039/5158 ,  C12N5/0636 ,  C12N2510/00

    摘要： The invention provides methods of preparing autologous T-lymphocytes for re-introduction into a patient having cancer, which method comprises obtaining peripheral blood mononuclear cells (PBMCs) from a patient immunized with an antigen of the cancer, stimulating the PBMCs with the antigen of the cancer in vitro, transducing the PBMCs with a retroviral vector, which (a) comprises and expresses a human interleukin-2 (IL-2) coding sequence operably linked to a retroviral promoter, (b) does not comprise an exogenously introduced gene that enables phenotypic selection, and (c) comprises a viral envelope that efficiently transduces CD8+ T-lymphocytes; compositions comprising cells obtained in accordance with such methods; and methods of treating a patient having cancer by administering to the patient cells obtained in accordance with such methods or compositions comprising same.

    摘要翻译： 本发明提供了制备自体T淋巴细胞以重新导入具有癌症的患者的方法，该方法包括从用癌抗原免疫的患者获得外周血单核细胞（PBMC），用抗原的抗原刺激PBMC （a）包含并表达与逆转录病毒启动子可操作地连接的人白细胞介素-2（IL-2）编码序列，（b）不包含外源导入的基因，其使得能够 表型选择，和（c）包含有效转导CD8 + T淋巴细胞的病毒包膜; 包含根据这些方法获得的细胞的组合物; 以及通过给予根据这样的方法获得的患者细胞治疗患有癌症的患者的方法或组合物的方法。

    Combining decision metrics for decoding based on payload difference
    2.
    发明授权
    Combining decision metrics for decoding based on payload difference 有权
    基于有效载荷差异组合用于解码的决策度量

    公开(公告)号：US08467480B2

    公开(公告)日：2013-06-18

    申请号：US12878906

    申请日：2010-09-09

    申请人： Ke Liu ,  Kibeom Seong ,  Tao Luo ,  Yongbin Wei

    发明人： Ke Liu ,  Kibeom Seong ,  Tao Luo ,  Yongbin Wei

    IPC分类号： H03D1/00 ,  H04L27/06

    CPC分类号： H04L1/0045 ,  H04L1/08

    摘要： Decision metrics used to decode wireless communication payloads are combined for successive frames to improve decoding of the later received frames. A bitwise payload difference between successive frames is encoded in the same manner the payloads are encoded. Decision metrics determined for the earlier received frame are combined with the encoded payload difference to generate adjusted decision metrics. The adjusted decision metrics are combined with decision metrics determined for the later received frame. The combined decision metrics are decoded to generate a payload for the later received frame. If the decoding is not successful the combined decision metrics are carried forward and the process is repeated based on the payload difference between the following frames.

    摘要翻译： 用于解码无线通信有效载荷的决策度量被组合用于连续的帧，以改进后续接收的帧的解码。 连续帧之间的按位有效负载差异以有效载荷编码的相同方式进行编码。 将针对较早接收到的帧确定的决策度量与经编码的有效载荷差值相组合以产生经调整的决策度量。 经调整的决策度量与为稍后接收的帧确定的决策度量相结合。 对组合决策度量进行解码，以生成稍后接收的帧的有效载荷。 如果解码不成功，则组合决策度量被转发，并且基于以下帧之间的有效负载差重复该过程。

    Method and Apparatus for Managing Message
    4.
    发明申请
    Method and Apparatus for Managing Message 有权
    管理信息的方法和装置

    公开(公告)号：US20130031178A1

    公开(公告)日：2013-01-31

    申请号：US13613590

    申请日：2012-09-13

    申请人： Chunpeng Wang ,  Ying Li ,  Ke Liu ,  Bin Li ,  Qinan Xiong ,  Huan Xiong

    发明人： Chunpeng Wang ,  Ying Li ,  Ke Liu ,  Bin Li ,  Qinan Xiong ,  Huan Xiong

    IPC分类号： G06F15/16

    CPC分类号： H04L51/32

    摘要： The present invention provides a method and an apparatus for managing message, including: receiving a request to perform a predetermined operation by a first user on a first message, the first message published by a second user and was previously obtained by the first user before the request to perform the predetermined operation, the request comprising information associated with the predetermined operation on the first message; determining status information of the first message based on a first index of the first message; sending the first message to the first user based on the status information.

    摘要翻译： 本发明提供了一种用于管理消息的方法和装置，包括：接收第一用户对第一消息执行预定操作的请求，由第二用户发布的第一消息，并且之前由第一用户获得 请求执行预定操作，该请求包括与第一消息上的预定操作相关联的信息; 基于所述第一消息的第一索引确定所述第一消息的状态信息; 基于状态信息向第一用户发送第一消息。

    Selection of acquisition sequences for optimal frequency offset estimation
    5.
    发明授权
    Selection of acquisition sequences for optimal frequency offset estimation 失效
    选择最佳频偏估计的采集序列

    公开(公告)号：US08223908B2

    公开(公告)日：2012-07-17

    申请号：US12113409

    申请日：2008-05-01

    申请人： Peter Gaal ,  Byoung-Hoon Kim ,  Ke Liu ,  Tao Luo

    发明人： Peter Gaal ,  Byoung-Hoon Kim ,  Ke Liu ,  Tao Luo

    IPC分类号： H04L7/00

    CPC分类号： H04L27/261 ,  H04L25/0226

    摘要： Systems and methods are provided to generate a set of synchronization channel sequences that optimize time and frequency acquisition. A set of root indices of Zadoff-Chu sequences in a first domain (e.g., time domain) that optimize a performance metric or merit factor are identified. An optimal index is determined that also optimizes a performance metric in a reciprocal domain (e.g., frequency domain). Optimal indices satisfy a centro-symmetric relationship with respect to a half-value of sequence length: When 1 is an optimal index, N−1 is also an optimal root index. For sequences of length Q2=N, a base sequence generated with an optimal sequence can be utilized to generate at least two disparate optimal sequences through sign-flip, conjugation, and periodic modulation operations.

    摘要翻译： 提供系统和方法以产生优化时间和频率采集的一组同步信道序列。 识别优化性能度量或优点因子的第一域（例如，时域）中的Zadoff-Chu序列的一组根索引。 确定最优索引，该最优索引还优化互倒域（例如，频域）中的性能度量。 最优索引相对于序列长度的半值满足中心对称关系：当1是最优索引时，N-1也是最优根索引。 对于长度为Q2 = N的序列，可利用以最佳序列生成的碱基序列通过符号翻转，共轭和周期调制操作来生成至少两个不同的最佳序列。

    Internal combustion engine exhaust treatment having a single valve directing exhaust to dual NOx traps
    6.
    发明授权
    Internal combustion engine exhaust treatment having a single valve directing exhaust to dual NOx traps 失效
    具有将排气引导到双NOx捕集器的单个阀的内燃机排气处理

    公开(公告)号：US08136345B2

    公开(公告)日：2012-03-20

    申请号：US10946206

    申请日：2004-09-21

    申请人： Ke Liu ,  John G. Buglass

    发明人： Ke Liu ,  John G. Buglass

    IPC分类号： F01N3/00

    CPC分类号： F01N3/2033 ,  F01N3/0253 ,  F01N3/032 ,  F01N3/0814 ,  F01N3/0821 ,  F01N3/0878 ,  F01N2240/30 ,  Y02T10/24 ,  Y02T10/26

    摘要： A single valve (23, 50) directs engine exhaust (11, 12) toward alternative NOx traps (19, 20) which are adjacent to either diesel particulate filters (40, 41) or low temperature water gas shift catalysts (63, 64). Syngas is either provided from a source (54) or by in-line catalytic partial oxidizers (23, 24) which may have diesel oxidation catalysts ahead of them in the flow and which receive fuel from the engine fuel source (26) through nozzles (27, 28).

    摘要翻译： 单个阀门（23,50）将发动机排气（11,12）引向与柴油机微粒过滤器（40,41）或低温水煤气变换催化剂（63,64）相邻的替代NOx捕集器（19,20） 。 合成气可以由源（54）或直列催化部分氧化器（23,24）提供，其可以在流动中具有柴油氧化催化剂，并且通过喷嘴（...）从发动机燃料源（26）接收燃料 27，28）。

    DETERMINATION OF NETWORK SYNCHRONIZATION
    7.
    发明申请
    DETERMINATION OF NETWORK SYNCHRONIZATION 有权
    网络同步的确定

    公开(公告)号：US20120044928A1

    公开(公告)日：2012-02-23

    申请号：US13212829

    申请日：2011-08-18

    申请人： Kapil Bhattad ,  Tao Luo ,  Taesang Yoo ,  Xiaoxia Zhang ,  Xiliang Luo ,  Ke Liu ,  Durga Prasad Malladi

    发明人： Kapil Bhattad ,  Tao Luo ,  Taesang Yoo ,  Xiaoxia Zhang ,  Xiliang Luo ,  Ke Liu ,  Durga Prasad Malladi

    IPC分类号： H04J3/06

    CPC分类号： H04J11/0083 ,  H04B1/70718 ,  H04L5/0007 ,  H04W28/04 ,  H04W48/16 ,  H04W88/02

    摘要： User equipment (UE) associated with synchronous networks operate in a synchronous mode while UEs associated with asynchronous networks operate in an asynchronous mode. When operating in a synchronous mode, a UE can significantly improve performance of synchronization signal detection, data decoding, and tracking loop management by using the interference cancellation (IC) techniques that are not available in an asynchronous mode of operation. Obtaining synchronization indicators and determining the synchronization status of the current network by UE is disclosed. The determination may be based on the synchronization indicator, whether detected through signal detection, signal measurements, signal analysis, or the like.

    摘要翻译： 与同步网络相关联的用户设备（UE）以同步模式工作，而与异步网络相关联的UE以异步模式工作。 当在同步模式下工作时，UE可以通过使用在异步操作模式中不可用的干扰消除（IC）技术来显着提高同步信号检测，数据解码和跟踪环路管理的性能。 公开了获取同步指示符并确定UE当前网络的同步状态。 该确定可以基于通过信号检测，信号测量，信号分析等检测的同步指示器。

    CONTROL SYSTEMS AND METHODS FOR CONTROLLING A DRY FEED SYSTEM TO CONVEY A SOLID FUEL
    8.
    发明申请
    CONTROL SYSTEMS AND METHODS FOR CONTROLLING A DRY FEED SYSTEM TO CONVEY A SOLID FUEL 有权
    用于控制干燥进料系统以输送固体燃料的控制系统和方法

    公开(公告)号：US20110301761A1

    公开(公告)日：2011-12-08

    申请号：US13112386

    申请日：2011-05-20

    申请人： Xu FU ,  Zhongzhi Hu ,  Tong Zhao ,  Zili Cai ,  Yao Chen ,  Baoming Huang ,  Wei Chen ,  Ke Liu

    发明人： Xu FU ,  Zhongzhi Hu ,  Tong Zhao ,  Zili Cai ,  Yao Chen ,  Baoming Huang ,  Wei Chen ,  Ke Liu

    IPC分类号： G05D11/02

    CPC分类号： G05D7/0605 ,  F23G2205/20 ,  F23K3/02 ,  Y02T10/32 ,  Y02T10/34

    摘要： A control system for controlling a dry feed system to convey a solid fuel includes multiple sensors, a pressurizing gas controller, at least one assistant gas controller and multiple gas valves. The sensors generate multiple measurement signals signifying characteristics of the dry feed system. The pressuring gas controller calculates a feed tank pressure bias or/and a pressuring gas flow bias based on a solid flow rate and generates a first control signal based on the pressure bias or/and the pressurizing gas flow bias. The assistant gas controller calculates an assistant gas bias based on a solid loading ratio and generates a second control signal based on the assistant gas bias. The gas valves are driven by the first or/and second control signals to regulate the solid fuel. A control method is also described.

    摘要翻译： 用于控制干式进料系统以输送固体燃料的控制系统包括多个传感器，加压气体控制器，至少一个辅助气体控制器和多个气体阀。 传感器产生表示干式进料系统特性的多个测量信号。 加压气体控制器基于固体流量计算进料罐压力偏压和/和加压气体流量偏压，并且基于压力偏压或/和加压气体流动偏压产生第一控制信号。 辅助气体控制器基于固体负载比计算辅助气体偏压，并且基于辅助气体偏压产生第二控制信号。 气阀由第一或/和第二控制信号驱动以调节固体燃料。 还描述了控制方法。