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公开(公告)号：US20100081180A1
公开(公告)日：2010-04-01
申请号：US12579594
申请日：2009-10-15
CPC分类号： C12P7/46
摘要： An organic acid is produced by allowing a bacterium which has an ability to produce an organic acid and has been modified so that expression of yidE gene is enhanced, or a product obtained by processing the bacterium, to act on an organic raw material in a reaction mixture containing carbonate ions, bicarbonate ions, or carbon dioxide gas to produce the organic acid, and collecting the organic acid.
摘要翻译： 有机酸是通过使具有生产有机酸的能力的细菌进行改性的，以使yidE基因的表达增强，或通过加工细菌获得的产物作用于反应中的有机原料 含有碳酸根离子，碳酸氢根离子或二氧化碳气体的混合物以产生有机酸，并收集有机酸。
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公开(公告)号：US20100112647A1
公开(公告)日：2010-05-06
申请号：US12579577
申请日：2009-10-15
申请人： Yoshihiko Hara , Keita Fukui , Yoshinori Tajima , Kazue Kawamura , Yoshihiro Usuda , Kazuhiko Matsui
发明人： Yoshihiko Hara , Keita Fukui , Yoshinori Tajima , Kazue Kawamura , Yoshihiro Usuda , Kazuhiko Matsui
IPC分类号： C12P13/20 , C12N1/20 , C12N1/21 , C12P13/14 , C12P7/40 , C12P7/58 , C12P7/42 , C12P7/46 , C12P7/48 , C12P7/50
CPC分类号： C12P13/14 , C07K14/195 , C07K14/245 , C07K14/265 , C12P7/46 , C12P7/48 , C12P7/50 , C12P13/20
摘要： An acidic substance having a carboxyl group is produced by culturing in a medium a microorganism which has been modified to enhance expression of the ybjL gene, and collecting the acidic substance having a carboxyl group from the medium.
摘要翻译： 具有羧基的酸性物质是通过在培养基中培养已被改良以增强ybjL基因表达的微生物，并从培养基中收集具有羧基的酸性物质产生的。
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公开(公告)号：US08076111B2
公开(公告)日：2011-12-13
申请号：US12579594
申请日：2009-10-15
IPC分类号： C12P7/46 , C12P1/04 , C12P21/06 , C12P19/34 , C12N1/20 , C12N9/00 , C07H21/02 , C07H21/04 , C07K1/00
CPC分类号： C12P7/46
摘要： An organic acid is produced by allowing a bacterium which has an ability to produce an organic acid and has been modified so that expression of yidE gene is enhanced, or a product obtained by processing the bacterium, to act on an organic raw material in a reaction mixture containing carbonate ions, bicarbonate ions, or carbon dioxide gas to produce the organic acid, and collecting the organic acid.
摘要翻译： 有机酸是通过使具有生产有机酸的能力的细菌进行改性的，以使yidE基因的表达增强，或通过加工细菌获得的产物作用于反应中的有机原料 含有碳酸根离子，碳酸氢根离子或二氧化碳气体的混合物以产生有机酸，并收集有机酸。
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公开(公告)号：US08367371B2
公开(公告)日：2013-02-05
申请号：US12420934
申请日：2009-04-09
IPC分类号： C12P1/00
CPC分类号： C12N9/88 , C12P13/08 , C12P13/227
摘要： A bacterium which belongs to the Enterobacteriaceae family and has an ability to produce an L-amino acid such as L-lysine, L-threonine and L-tryptophan and is modified to enhance glutamic acid decarboxylase activity is cultured in a medium to produce and accumulate the L-amino acid in the medium or cells of the bacterium. Then, the L-amino acid is collected from the medium or the cells.
摘要翻译： 属于肠杆菌科的具有生产L-赖氨酸，L-苏氨酸和L-色氨酸的L-氨基酸的能力并经过修饰以增强谷氨酸脱羧酶活性的细菌在培养基中培养以产生和积累 细菌的培养基或细胞中的L-氨基酸。 然后，从培养基或细胞收集L-氨基酸。
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公开(公告)号：US20090239269A1
公开(公告)日：2009-09-24
申请号：US12420934
申请日：2009-04-09
CPC分类号： C12N9/88 , C12P13/08 , C12P13/227
摘要： A bacterium which belongs to the Enterobacteriaceae family and has an ability to produce an L-amino acid such as L-lysine, L-threonine and L-tryptophan and is modified to enhance glutamic acid decarboxylase activity is cultured in a medium to produce and accumulate the L-amino acid in the medium or cells of the bacterium. Then, the L-amino acid is collected from the medium or the cells.
摘要翻译： 属于肠杆菌科的具有生产L-赖氨酸，L-苏氨酸和L-色氨酸的L-氨基酸的能力并经过修饰以增强谷氨酸脱羧酶活性的细菌在培养基中培养以产生和积累 细菌的培养基或细胞中的L-氨基酸。 然后，从培养基或细胞收集L-氨基酸。
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公开(公告)号：US08247201B2
公开(公告)日：2012-08-21
申请号：US12793107
申请日：2010-06-03
CPC分类号： C12N9/88 , C08G69/10 , C12P7/46 , C12Y401/01031
摘要： An organic acid is produced by allowing a bacterium belonging to the family Enterobacteriaceae, which has an ability to produce an organic acid and has been modified so that the phosphoenolpyruvate carboxykinase activity is enhanced, which is selected from Enterobacter, Pantoea, Erwinia, Klebsiella and Raoultella bacteria, or a product obtained by processing the bacterium, to act on an organic raw material in a reaction mixture containing carbonate ions, bicarbonate ions, or carbon dioxide gas to produce the organic acid, and collecting the organic acid.
摘要翻译： 有机酸是通过使属于肠杆菌科的细菌，其具有产生有机酸的能力并被修饰以使得磷酸烯醇丙酮酸羧激酶活性增强，其选自肠杆菌属，泛菌属，欧文氏菌属，克雷伯菌属 细菌或通过加工细菌获得的产品在含有碳酸根离子，碳酸氢根离子或二氧化碳气体的反应混合物中作用于有机原料以产生有机酸，并收集有机酸。
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公开(公告)号：US20100297716A1
公开(公告)日：2010-11-25
申请号：US12793107
申请日：2010-06-03
IPC分类号： C12P7/46
CPC分类号： C12N9/88 , C08G69/10 , C12P7/46 , C12Y401/01031
摘要： An organic acid is produced by allowing a bacterium belonging to the family Enterobacteriaceae, which has an ability to produce an organic acid and has been modified so that the phosphoenolpyruvate carboxykinase activity is enhanced, which is selected from Enterobacter, Pantoea, Erwinia, Klebsiella and Raoultella bacteria, or a product obtained by processing the bacterium, to act on an organic raw material in a reaction mixture containing carbonate ions, bicarbonate ions, or carbon dioxide gas to produce the organic acid, and collecting the organic acid.
摘要翻译： 有机酸是通过使属于肠杆菌科的细菌，其具有产生有机酸的能力并被修饰以使得磷酸烯醇丙酮酸羧激酶活性增强，其选自肠杆菌属，泛菌属，欧文氏菌属，克雷伯菌属 细菌或通过加工细菌获得的产品在含有碳酸根离子，碳酸氢根离子或二氧化碳气体的反应混合物中作用于有机原料以产生有机酸，并收集有机酸。
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公开(公告)号：US08497104B2
公开(公告)日：2013-07-30
申请号：US13301096
申请日：2011-11-21
申请人： Yoshinori Tajima , Yoko Yamamoto
发明人： Yoshinori Tajima , Yoko Yamamoto
IPC分类号： C12P7/46
CPC分类号： C12P7/46
摘要： An organic acid is produced by allowing a bacterium belonging to the family Enterobacteriaceae, which has an ability to produce an organic acid and has been modified so that the phosphoenolpyruvate carboxykinase activity is enhanced, and the glucose phosphotransferase activity is decreased, which is selected from Escherichia, Enterobacter, Pantoea, Erwinia, Klebsiella and Raoultella bacteria, or a product obtained by processing the bacterium, to act on an organic raw material in a reaction mixture containing carbonate ions, bicarbonate ions, or carbon dioxide gas to produce the organic acid.
摘要翻译： 有机酸通过使属于肠杆菌科的细菌产生，该细菌具有产生有机酸的能力，并被修饰，使得磷酸烯醇丙酮酸羧激酶活性增强，葡萄糖磷酸转移酶活性降低，其选自大肠杆菌 ，肠杆菌属，泛菌属，欧文氏菌属，克雷伯氏菌属和毛霉属细菌，或通过加工细菌获得的产物在含有碳酸根离子，碳酸氢根离子或二氧化碳气体的反应混合物中作用于有机原料以产生有机酸。
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公开(公告)号：US20120129233A1
公开(公告)日：2012-05-24
申请号：US13301096
申请日：2011-11-21
申请人： Yoshinori Tajima , Yoko Yamamoto
发明人： Yoshinori Tajima , Yoko Yamamoto
IPC分类号： C12P7/46
CPC分类号： C12P7/46
摘要： An organic acid is produced by allowing a bacterium belonging to the family Enterobacteriaceae, which has an ability to produce an organic acid and has been modified so that the phosphoenolpyruvate carboxykinase activity is enhanced, and the glucose phosphotransferase activity is decreased, which is selected from Escherichia, Enterobacter, Pantoea, Erwinia, Klebsiella and Raoultella bacteria, or a product obtained by processing the bacterium, to act on an organic raw material in a reaction mixture containing carbonate ions, bicarbonate ions, or carbon dioxide gas to produce the organic acid.
摘要翻译： 有机酸通过使属于肠杆菌科的细菌产生，该细菌具有产生有机酸的能力，并被修饰，使得磷酸烯醇丙酮酸羧激酶活性增强，葡萄糖磷酸转移酶活性降低，其选自大肠杆菌 ，肠杆菌属，泛菌属，欧文氏菌属，克雷伯氏菌属和毛霉属细菌，或通过加工细菌获得的产物，在含有碳酸根离子，碳酸氢根离子或二氧化碳气体的反应混合物中作用于有机原料以产生有机酸。
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公开(公告)号：US20070051020A1
公开(公告)日：2007-03-08
申请号：US10576200
申请日：2004-10-21
IPC分类号： A43B5/00
CPC分类号： A43B5/12 , A43B3/0042 , A43B5/001 , A43B7/24 , A43B13/14 , A43B13/143
摘要： A sole 12 of shoe 10 has a thickened portion defined at an area thereof where a base of toe of user's foot is to be positioned. An engagement is member 30 adapted for allowing a rotating adapter 20 to be releasably engaged therewith. In an inner surface of the shoe 10, there are provided: a slope inclined, as indicated by the line LA, such that a side thereof near to the heel side 16 is low; and a slope inclined, as indicated by the line LB, such that one side thereof on which a big toe of user's foot is to be positioned is lower than another side thereof on which a small toe of user's foot is to be positioned. The sole 12 is formed with a sloped surface 18 which extends from an area of the sole at which the base of toe of user's foot is to be positioned, in a direction toward a toe side 14.
摘要翻译： 靴子10的鞋底12具有限定在其用户脚的脚趾的基部定位的区域处的加厚部分。 接合件是适于允许旋转适配器20与其可释放地接合的构件30。 在鞋10的内表面中，设有倾斜的斜面，如线LA所示，使其靠近脚跟侧16的一侧较低; 以及如由线LB所示倾斜的斜面，使得其用户脚的大脚趾位于其上的一侧低于其上要放置用户脚的小脚趾的另一侧。 鞋底12形成有倾斜表面18，该倾斜表面18沿着朝向脚趾侧14的方向从脚趾的脚趾的底部将要被定位的鞋底的区域延伸。
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