Low-molecular weight peptide mixture and method of producing same
    1.
    发明授权
    Low-molecular weight peptide mixture and method of producing same 失效
    低分子量肽混合物及其制备方法

    公开(公告)号:US4940662A

    公开(公告)日:1990-07-10

    申请号:US794322

    申请日:1985-11-01

    CPC分类号: C07K1/126 C12P21/02 C12P21/06

    摘要: A method of producing a low-molecular weight peptide mixture, comprising the steps of dissolving a first protease in a buffer solution adjusted to an optimum pH for the protease ranging from pH 3 to 10, adding at least one first protein in a buffer solution having a pH of from 3 to 10 and a concentration of 10 to 60% by weight of the protein material and thoroughly mixing the solution, adding a solution of an ester of at least one amino acid pre-formed by esterification of the amino acid with an alcohol, the pH of said buffer solution being optimum for the incorporation of said amino acid in said starting protein in the presence of said first protease in a plastein reaction, reacting said ester of at least one amino acid with said starting protein in a plastein reaction in the mixed solution whereby said at least one amino acid is covalently incorporated into said starting protein to produce a plastein reaction solution containing a modified protein, hydrolyzing said modified protein using at least one second protease having a different specificity from said at least one first protease to produce a low-molecular weight peptide mixture having an amino acid content which has different proportions of amino acids than does said starting protein, and separating from the solution said low-molecular weight peptide mixture which comprises a major proportion of dipeptides and tripeptides and containing not more than 15% by weight of free amino acids and not more than 20% by weight of a high-molecular weight fraction of compounds having a molecular weight of not lower than 700 and removable by gel filtration. The said low-molecular weight peptide mixture is readily absorbable and a useful nutrient.

    摘要翻译: 一种生产低分子量肽混合物的方法,包括以下步骤:将第一蛋白酶溶解在缓冲溶液中,调节至最适pH为pH3至10的蛋白酶,加入至少一种第一蛋白质的缓冲溶液中, pH为3至10,浓度为蛋白质材料的10至60重量%,并将溶液充分混合,加入通过氨基酸酯化预先形成的至少一个氨基酸的酯溶液与 醇,所述缓冲溶液的pH最适于在所述起始蛋白质中在所述第一蛋白酶存在下在Plastein反应中引入所述氨基酸,使所述至少一个氨基酸的所述酯与所述起始蛋白质在Plastein反应中反应 在所述混合溶液中,其中所述至少一个氨基酸共价掺入所述起始蛋白质中以产生含有修饰蛋白质的粘多糖反应溶液,水解所述修饰的蛋白质u 与至少一种第一蛋白酶具有不同特异性的至少一种第二蛋白酶,以产生具有与所述起始蛋白质不同比例的氨基酸的氨基酸含量的低分子量肽混合物,并从所述溶液中分离出所述第 低分子量肽混合物,其包含主要比例的二肽和三肽,并且含有不超过15重量%的游离氨基酸和不超过20重量%的高分子量级分的分子量为 不低于700,可通过凝胶过滤去除。 所述低分子量肽混合物易于吸收和有用的营养物质。

    Positioning control apparatus and machine tool provided therewith
    2.
    发明授权
    Positioning control apparatus and machine tool provided therewith 有权
    定位控制装置和机床

    公开(公告)号:US09110458B2

    公开(公告)日:2015-08-18

    申请号:US13349783

    申请日:2012-01-13

    IPC分类号: G05B19/19 G05D3/10 G05B19/404

    CPC分类号: G05B19/404 G05B2219/41056

    摘要: A positioning control apparatus has a moving body, a feed device having a guide mechanism for guiding the moving body in the direction of its feed axis and a drive mechanism for moving the moving body, a structural body supporting the feed device and a controller for controlling a moving position of the moving body with respect to a reference position on a machine tool by controlling the operation of the drive mechanism, and further has a calculating section calculating displacement of the feed device in the feed-axis direction with respect to the reference position caused by displacement of the structural body and a compensating section receiving the displacement data measured by the calculating section and adding modification data for eliminating the displacement to a control signal in the controller.

    摘要翻译: 定位控制装置具有移动体,具有引导机构的进给装置,该引导机构用于沿着其进给轴线的方向引导移动体,以及用于使移动体移动的驱动机构,支撑进给装置的结构体和控制器 通过控制所述驱动机构的动作,使所述移动体相对于机床上的基准位置的移动位置,还具有计算部,计算所述进给装置相对于所述基准位置的进给轴方向的位移 由结构体的位移引起的补偿部分和接收由计算部分测量的位移数据的补偿部分,并将用于消除位移的修改数据添加到控制器中的控制信号。

    Base station apparatus and transmission control method
    3.
    发明授权
    Base station apparatus and transmission control method 有权
    基站装置和传输控制方法

    公开(公告)号:US09094848B2

    公开(公告)日:2015-07-28

    申请号:US13816786

    申请日:2010-08-23

    摘要: A base station apparatus, when performing the transmission controls of pico base stations, can perform an appropriate transmission control for each pico base station, while suppressing the increase of the amount of feedback information from a macro terminal to a macro base station and also suppressing the increase of the amount of transmission control information from the macro base station to the pico base station. In this apparatus, a transmission control unit (102) updates, on the basis of the control information, the priority level of each of a plurality of different correspondences in which the respective ones of transmission control guidelines are associated with the respective ones of a plurality of control information history patterns, and controls the transmissions on the basis of the control guidelines determined from the control information histories and the correspondences each having a respective higher priority level.

    摘要翻译: 基站装置在执行微微基站的发送控制时,可以在抑制从宏终端到宏基站的反馈信息量的增加的同时,抑制各个微基站的发送控制, 传输控制信息量从宏基站增加到微微基站。 在该装置中,发送控制部(102)基于控制信息,更新各个发送控制指示与多个不同对应关系中的各个对应关系的优先级, 并且基于从控制信息历史确定的控制指南和每个具有相应较高优先级的对应来控制传输。

    Method for assaying keratan sulfate, assay kit therefor and method for detecting joint disease by using the same
    4.
    发明授权
    Method for assaying keratan sulfate, assay kit therefor and method for detecting joint disease by using the same 有权
    用于测定硫酸角质素的方法,其测定试剂盒及其用于检测关节疾病的方法

    公开(公告)号:US08822229B2

    公开(公告)日:2014-09-02

    申请号:US13142262

    申请日:2009-12-24

    IPC分类号: G01N33/564

    摘要: The inventions provides a method for immunologically determining a keratan sulfate level which method includes bringing an anti-keratan sulfate monoclonal antibody into contact with a biological sample, the anti-keratan sulfate monoclonal antibody exhibiting a relative reaction specificity between keratan sulfate-I and keratan sulfate-II represented by IC50KS-I/KS-II of 0.4 to 5, to thereby provide a signal; and detecting keratan sulfate contained in the biological sample from the signal. On the basis of the method, the invention also provides a joint disease detection method and a method for assessing the effect of a remedy for a joint disease and a candidate substance therefor. Through these methods, a very small amount of keratan sulfate contained in a sample, can be determined. Particularly, these methods can determine, at high-sensitivity and high-specificity, the total keratan sulfate including keratan sulfate-I, which have been difficult to determine through a conventional technique. The methods also enables detect a joint disease and assess the effect of a remedy for a joint disease or a candidate substance therefor.

    摘要翻译: 本发明提供了一种免疫测定硫酸角质素水平的方法,该方法包括使硫酸角质素硫酸单克隆抗体与生物样品接触,硫酸角质素-I与硫酸角质素之间呈现相对反应特异性的硫酸角质素单体抗体 -II由IC50KS-I / KS-II表示,为0.4〜5,从而提供信号; 并从信号中检测生物样品中所含的硫酸角质素。 在该方法的基础上,本发明还提供了关于联合疾病的检测方法和评估对于关节疾病及其候选物质的补救效果的方法。 通过这些方法,可以测定样品中所含的极少量硫酸角质素。 特别地,这些方法可以高灵敏度和高特异性地确定通过常规技术难以确定的总硫酸角质素,包括硫酸角质素-I。 该方法还能够检测关节疾病并评估对于关节疾病或候选物质的补救的效果。

    Fixing device that fixes a toner image on a recording material
    5.
    发明授权
    Fixing device that fixes a toner image on a recording material 有权
    将墨粉图像固定在记录材料上的固定装置

    公开(公告)号:US08634752B2

    公开(公告)日:2014-01-21

    申请号:US12910410

    申请日:2010-10-22

    IPC分类号: G03G15/20

    CPC分类号: G03G15/2028

    摘要: A fixing device fixing a toner image on a recording material includes a first blowing section that blows air against a leading edge of the recording material that has passed through a nip portion formed by a heated fixing member and a pressing member kept in pressure contact with the fixing member, and a second blowing section that blows air against the recording material that has passed through the nip portion, wherein an air speed of air blown out from a first blowing outlet is higher than that of air blown out from a second blowing outlet, wherein an air flow amount from the first blowing outlet is less than that from the second blowing outlet, and wherein the first and second blowing outlets are arranged at a same positional height next to one another along a rotational axis of the fixing roller.

    摘要翻译: 将调色剂图像固定在记录材料上的定影装置包括:第一吹风部,其将空气吹向已经通过由加热的固定部件形成的辊隙部的记录材料的前端,以及与该保持压力接触的压紧部件 以及第二吹送部,其将空气吹过已经通过所述夹持部的记录材料,其中从第一吹出口吹出的空气的空气速度高于从第二吹出口吹出的空气的空气速度, 其中来自所述第一吹出口的空气流量小于来自所述第二吹出口的空气流量,并且其中所述第一吹出口和所述第二吹出口沿着所述定影辊的旋转轴线彼此相邻布置在相同的位置高度处。

    Video processing apparatus and video processing method
    6.
    发明授权
    Video processing apparatus and video processing method 失效
    视频处理装置和视频处理方法

    公开(公告)号:US08630532B2

    公开(公告)日:2014-01-14

    申请号:US12382827

    申请日:2009-03-24

    IPC分类号: H04N5/93

    摘要: A video processing apparatus calculates displayed time of two input segments having a telop area in a video on the basis of a time displayed area, determines whether or not the two input segments are a series of scene segments on the basis of the two displayed times, and outputs the two input segments determined as the series of scene segments as an output segment.

    摘要翻译: 视频处理装置基于时间显示区域计算视频中具有字幕区域的两个输入段的显示时间,基于两个显示时间确定两个输入段是否是一系列场景段, 并输出确定为一系列场景段的两个输入段作为输出段。

    Semiconductor storage device operative to search for data
    7.
    发明授权
    Semiconductor storage device operative to search for data 有权
    用于搜索数据的半导体存储设备

    公开(公告)号:US08625360B2

    公开(公告)日:2014-01-07

    申请号:US13165457

    申请日:2011-06-21

    IPC分类号: G11C7/10

    CPC分类号: G11C15/04

    摘要: To provide a semiconductor storage device capable of performing a search of the next data while performing a search of certain data. A first comparator compares data output to a bit line from a memory cell with first search data by activating a word line. A second comparator compares data output to a bit line from the memory cell with second search data by activating a word line. Data output to a bit line by the activation of one word line is input to both the first comparator and second comparator.

    摘要翻译: 提供能够在执行某些数据的搜索的同时对下一个数据进行搜索的半导体存储装置。 第一比较器通过激活字线将来自存储器单元的数据输出与第一搜索数据进行比较。 第二比较器通过激活字线将来自存储器单元的数据输出与第二搜索数据进行比较。 通过一个字线的激活将数据输出到位线被输入到第一比较器和第二比较器。

    Fixing device and image forming apparatus provided therewith
    8.
    发明授权
    Fixing device and image forming apparatus provided therewith 有权
    固定装置及其设置的图像形成装置

    公开(公告)号:US08571454B2

    公开(公告)日:2013-10-29

    申请号:US13226917

    申请日:2011-09-07

    IPC分类号: G03G15/20

    CPC分类号: G03G15/2028 G03G2215/20

    摘要: A fixing device includes: a heating section which heats a recording material; a pressing section which presses the recording material toward the heating section; a separation claw which separates the recording material from the heating section or the pressing section; a fixing unit moving section which reciprocates the heating section, the pressing section and the separation claw in a direction perpendicular to a conveyance direction of the recording material; and a separation claw moving section which reciprocates the separation claw in the direction perpendicular to the conveyance direction, wherein the separation claw moving section moves the separation claw toward a direction opposite to a moving direction toward which the heating section, the pressing section and the separation claw move in the direction perpendicular to the conveyance direction.

    摘要翻译: 定影装置包括:加热部,其加热记录材料; 将记录材料朝向加热部按压的按压部; 分离爪,其将记录材料与加热部分或按压部分分离; 固定单元移动部分,其使加热部分,按压部分和分离爪沿与记录材料的传送方向垂直的方向往复运动; 以及分离爪移动部,其使分离爪在与输送方向垂直的方向上往复运动,其中分离爪移动部使分离爪朝向与加热部,按压部和分离部的移动方向相反的方向移动 爪沿与输送方向垂直的方向移动。

    Fixing device and image forming apparatus having sheet separation device
    9.
    发明授权
    Fixing device and image forming apparatus having sheet separation device 有权
    具有片材分离装置的固定装置和成像装置

    公开(公告)号:US08543044B2

    公开(公告)日:2013-09-24

    申请号:US13070223

    申请日:2011-03-23

    IPC分类号: G03G15/20

    CPC分类号: G03G15/2028

    摘要: A fixing device conveying a sheet carrying a toner image under heating and pressurization at a nip section and fixing the toner image on the sheet comprising; a fixing member provided with a heating member, a pressure member pressing on the fixing member and forming the nip section which sandwiches the sheet carrying the toner image; a blower duct equipped with an outlet opening toward a vicinity of a sheet outlet of the nip section; a blower member for blowing air in a vicinity of the sheet outlet through the blower duct; and a guide device provided with a guide member for guiding the sheet ejected from the nip section arranged on an upper side of a sheet conveyance path; and, further comprising a biasing member for biasing the sheet toward the guide member, in the vicinity of the nip section.

    摘要翻译: 一种定影装置,其在夹持部分处加热和加压地输送载有调色剂图像的片材,并将所述调色剂图像定影在所述片材上; 设置有加热构件的固定构件,压在固定构件上的压力构件,并形成夹持承载调色剂图像的片材的夹持部; 鼓风机管道,其具有朝向所述夹持部的片材出口附近的出口开口; 鼓风机构件,用于通过鼓风机管道吹出出纸口附近的空气; 以及引导装置,其具有引导构件,用于引导从布置在片材传送路径的上侧的夹持区域排出的片材; 并且还包括用于在所述夹持部分附近朝向所述引导构件偏压所述片材的偏置构件。

    VIDEO PROCESSING APPARATUS AND METHOD
    10.
    发明申请
    VIDEO PROCESSING APPARATUS AND METHOD 有权
    视频处理设备和方法

    公开(公告)号:US20130156321A1

    公开(公告)日:2013-06-20

    申请号:US13705399

    申请日:2012-12-05

    IPC分类号: G06T7/00

    摘要: In one embodiment, a method is disclosed for performing a video processing. The method can extract one or more common video segments. The method can select a common summarization segment based on a first summarization score. The method can extract one or more individual video segments in which the number of segments included therein is not more than a third threshold value that is less than a second threshold value. The method can select an individual summarization segment based on a second summarization score. In addition, the method can integrate the common summarization segment and the individual summarization segment to create the summary video.

    摘要翻译: 在一个实施例中,公开了一种用于执行视频处理的方法。 该方法可以提取一个或多个常见的视频片段。 该方法可以基于第一个总结分数来选择一个公共摘要段。 该方法可以提取其中包括在其中的段的数量不超过小于第二阈值的第三阈值的一个或多个单独视频段。 该方法可以基于第二个总结分数来选择单个汇总分段。 此外,该方法可以将公共摘要段和个人摘要段进行整合,创建摘要视频。