-
公开(公告)号：US5889046A
公开(公告)日：1999-03-30
申请号：US595209
申请日：1996-02-01
IPC分类号： A23C15/12 , A23L1/30 , A61K31/34 , A61K31/357 , A61K31/36 , A61P9/12 , A61K31/335
CPC分类号： A61K31/357 , A61K31/36
摘要： The present invention discloses a preventive or ameliorant of hypertension or medical symptoms caused by it and a food or beverage that prevents or ameliorates hypertension or medical symptoms caused by it that contain for its active ingredient dioxabicyclo�3.3.0!octane derivative represented by the formula (2). ##STR1## wherein, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are respectively and independently a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, or R.sup.1 and R.sup.2 and/or R.sup.4 and R.sup.5 collectively represent a methylene group or ethylene group, and n, m and L represent 0 or 1.
摘要翻译： 本发明公开了一种预防或改善由其引起的高血压或由其引起的医学症状以及食物或饮料，其预防或改善由其引起的高血压或医学症状，所述高血压或医学症状包含其活性成分二氧二环〔3.3.0〕辛烷衍生物 （2）。 其中，R 1，R 2，R 3，R 4，R 5和R 6分别独立地为氢原子或具有1至3个碳原子的烷基，或者R 1和R 2和/或R 4和R 5共同表示亚甲基或 乙烯基，n，m和L表示0或1。
-
公开(公告)号：US5116751A
公开(公告)日：1992-05-26
申请号：US643166
申请日：1991-01-22
CPC分类号： C12N9/0065 , C12Q1/28 , Y10S435/911
摘要： A novel peroxidase was obtained from a fast growing microorganism of the genus Coprinus cinereus. The fungal peroxidase is comparable to the conventional peroxidase derived from horseradish or Japanese radish in that it can be used either as a clinical or diagnostic reagent or as a marker enzyme in enzyme immunoassay.
摘要翻译： 一种新型过氧化物酶是从快速生长的灰霉菌属微生物获得的。 真菌过氧化物酶与来自辣根或日本萝卜的常规过氧化物酶相当，因为它可以作为临床或诊断试剂或作为酶免疫测定中的标记酶使用。
-
公开(公告)号：US4427657A
公开(公告)日：1984-01-24
申请号：US274454
申请日：1981-06-17
IPC分类号： C12Q1/04 , A61K38/00 , C07K14/415 , C12Q1/70 , A61K37/00
CPC分类号： C07K14/415 , C12Q1/70 , A61K38/00 , Y10S930/26
摘要： Certain noval polypeptides and their use as carcinostatic agents and as agents for the detection and determination of viruses. The polypeptides contain forty-five amino acid residues and have a peculiar tetracyclic structure in that they are bridged with four disulfide bonds between each crysteine molecular pair, said pairs being present between the 3rd and 39th, 4th and 31st, 12th and 29th and 16th and 25th positions, respectively.
摘要翻译： 某些noval多肽及其作为制癌剂的用途和用于检测和测定病毒的试剂。 多肽含有四十五个氨基酸残基，并且具有特殊的四环结构，因为它们在每个结晶分子对之间桥接四个二硫键，所述对存在于第3和第39和第4和第31，第12和第29和第16和第 第25名。
-
4.发明授权Composition for increasing potency of adriamycin or daunomycin and reducing toxicities thereof 失效用于增加阿霉素或道诺霉素效力的组合物，并减少其毒性
公开(公告)号：US4900538A
公开(公告)日：1990-02-13
申请号：US70155
申请日：1987-07-02
申请人： Yoshihide Suwa , Noriko Kiyota , Hajime Yoshizumi , Shiro Senoh
发明人： Yoshihide Suwa , Noriko Kiyota , Hajime Yoshizumi , Shiro Senoh
IPC分类号： A61K31/70 , A61K33/04 , C07H15/252
CPC分类号： C07H15/252 , A61K33/04 , Y10S514/922
摘要： The pressent invention provides a composition comprising adriamycin or daunomycin in mixture with one or more compounds selected from sulfite, acid sulfite, pyrosulfite, diothionite and sulfurous anhydride in order to reduce the toxicities of adriamycin or daunomycin and to increase the potency thereof and a method comprising administering said compounds in mixture with adriamycin or daunomycin.By the composition and method of the present invention the safe and effective treatment of various tumors with adriamycin and daunomycin, which have remarkably high potency, but also have serious side effects, will be provided.
摘要翻译： PCT No.PCT / JP83 / 00457 Sec。 371日期1984年8月27日第 102（e）日期1984年8月27日PCT提交1983年12月27日PCT公布。 出版物WO84 / 02527 日本1984年7月5日。本发明提供了一种包含阿霉素或道诺霉素与一种或多种选自亚硫酸盐，亚硫酸氢盐，焦亚硫酸盐，二硫代磷酸盐和亚硫酸酐的化合物的组合物，以减少阿霉素或道诺霉素的毒性并增加 其效力和包括与阿霉素或道诺霉素混合施用所述化合物的方法。 通过本发明的组合物和方法，将提供具有显着高效力但具有严重副作用的阿霉素和道诺霉素的各种肿瘤的安全有效的治疗。
-
公开(公告)号：US4863864A
公开(公告)日：1989-09-05
申请号：US808742
申请日：1985-12-13
IPC分类号： C12N15/09 , C12N1/00 , C12N1/19 , C12N1/21 , C12N9/34 , C12N15/00 , C12N15/56 , C12N15/62 , C12R1/125 , C12R1/19 , C12R1/845 , C12R1/865
CPC分类号： C12N9/2428 , C07K2319/00 , C07K2319/02 , Y10S435/942
摘要： The present invention relates to the Rhizopus derived glucoamylase gene, a novel recombinant vector comprising said gene, and a microorganism transformed by said vector, as well as a process for reproducing Rhizopus glucoamylase by cultivating the transformed microorganism, especially yeast, in a liquid medium.
摘要翻译： 本发明涉及根霉衍生的葡糖淀粉酶基因，包含所述基因的新型重组载体和由所述载体转化的微生物，以及通过在液体培养基中培养转化的微生物特别是酵母来再现根霉属葡糖淀粉酶的方法。
-
6.发明授权Process for producing alcohol using yeast transformed by Rhizopus glucoamylase gene 失效利用红霉素转化酵母基因YEAST生产酒精的方法
公开(公告)号：US5084385A
公开(公告)日：1992-01-28
申请号：US338395
申请日：1989-04-14
CPC分类号： C12N9/2428 , C12P7/06 , Y02E50/17 , Y10S435/939
摘要： This invention provides a process for producing ethanol from a starchy material, wherein the starchy material is simultaneously subjected to saccharification and subsequent fermentation by use of a yeast host which has been transformed by an expressible recombinant vector comprising a glucoamylase gene derived from a fungus of the genus Rhizopus.
摘要翻译： 本发明提供了一种从淀粉质材料生产乙醇的方法，其中淀粉质材料同时进行糖化，随后通过使用酵母宿主进行发酵，该酵母宿主已经通过可表达的重组载体转化，所述酵母宿主包含源自真菌的葡糖淀粉酶基因 根霉属。
-
公开(公告)号：US4774185A
公开(公告)日：1988-09-27
申请号：US915026
申请日：1986-10-03
申请人： Sumio Asami , Norihide Amano , Teruo Amachi , Hajime Yoshizumi
发明人： Sumio Asami , Norihide Amano , Teruo Amachi , Hajime Yoshizumi
CPC分类号： C12N9/0089 , Y10S435/822
摘要： A novel superoxide dismutase prepared from a superoxide dismutase-producing strain of the genus Nocardiopsis. The enzyme is a tetramer with a molecular weight of about 8.8.times.10.sup.4, composed of sub-units of about 2.2.times.10.sup.4. The superoxide dismutase contains 1.56 g-atoms of iron per mole but no copper or manganese. Potassium cyanide at a concentration of 1 mM does not inhibit activity, however exponential inactivation is caused by 5 mM hydrogen peroxide.
摘要翻译： 一种由Nocardiopsis属超氧化物歧化酶生产菌株制备的新型超氧化物歧化酶。 该酶是分子量约为8.8×10 4的四聚物，由约2.2×10 4的亚单位组成。 超氧化物歧化酶每摩尔含有1.56克原子铁，但不含铜或锰。 浓度为1mM的氰化钾不抑制活性，但是由5mM过氧化氢引起指数失活。
-
公开(公告)号：US4497799A
公开(公告)日：1985-02-05
申请号：US319755
申请日：1981-11-09
IPC分类号： A61K38/00 , C07K14/415 , A61K37/00 , C07C103/52
CPC分类号： C07K14/415 , A61K38/00 , Y10S930/26
摘要： A carcinostatic agent containing a polypeptide of the formula ##SPC1##
摘要翻译： 一个
-
公开(公告)号：US4287185A
公开(公告)日：1981-09-01
申请号：US082657
申请日：1979-10-09
IPC分类号： C12Q1/04 , A61K38/00 , C07K14/415 , C12Q1/70 , A61K37/00 , C07C103/52
CPC分类号： C07K14/415 , C12Q1/70 , A61K38/00 , Y10S930/26
摘要： Certain novel polypeptides and their use as carcinostatic agents and as agents for the detection and determination of viruses. The polypeptides contain forty-five amino acid residues and have a peculiar tetracyclic structure in that they are bridged with four disulfide bonds between each cysteine molecular pair, said pairs being present between the 3rd and the 39th, 4th and 31st, 12th and 29th and 16th and 25th positions, respectively.
摘要翻译： 某些新型多肽及其作为制癌剂的用途以及用于检测和测定病毒的试剂。 多肽含有四十五个氨基酸残基，并且具有特殊的四环结构，因为它们在每个半胱氨酸分子对之间桥接四个二硫键，所述对存在于第3和第39和第4和第31，第12和第29和第16 和第25名。
-
公开(公告)号：US5006468A
公开(公告)日：1991-04-09
申请号：US271966
申请日：1988-11-16
CPC分类号： C12H1/003 , C12N9/80 , Y10S435/83
摘要： A novel urease and a process for producing the same are disclosed. This novel urease has certain properties that are mainly useful for removing urea from alcoholic liquors or other foods and beverages produced by fermentation. These properties include an optimum pH in an acidic pH range, high stability in a considerably high concentration of alcohol such as in an alcoholic liquor, resistance to high temperatures, and highly specific activity to urea.This urease can be produced by culturing a certain strain belonging to genus Arthrobacter, disrupting the cultured microbial cells and isolating the product.
-
-
-
-
-
-
-
-
-
搜索结果
18 条记录 (耗时 0.03 秒)
