摘要:
Certain novel polypeptides and their use as carcinostatic agents and as agents for the detection and determination of viruses. The polypeptides contain forty-five amino acid residues and have a peculiar tetracyclic structure in that they are bridged with four disulfide bonds between each cysteine molecular pair, said pairs being present between the 3rd and the 39th, 4th and 31st, 12th and 29th and 16th and 25th positions, respectively.
摘要:
Certain noval polypeptides and their use as carcinostatic agents and as agents for the detection and determination of viruses. The polypeptides contain forty-five amino acid residues and have a peculiar tetracyclic structure in that they are bridged with four disulfide bonds between each crysteine molecular pair, said pairs being present between the 3rd and 39th, 4th and 31st, 12th and 29th and 16th and 25th positions, respectively.
摘要:
An ailanthone derivative having the general formula: ##STR1## wherein R is a p-alkyl benzoic acid residue having 8 to 21 carbon atoms, a 2-methyl saturated fatty acid residue having 6 to 19 carbon atoms, a 2-methyl-2-unsaturated fatty acid residue having 4 to 19 carbon atoms, a 3,4-dimethyl-4-acyloxy-2-pentenoic acid residue having 9 to 19 carbon atoms, a 3,4,4-trimethyl-2-unsaturated fatty acid residue having 8 to 21 carbon atoms, a group having the formula ##STR2## wherein n is an integer of 1 to 13, a group having the general formula ##STR3## wherein n is an integer of 1 to 13, a trans-cinnamic acid residue, a linear saturated fatty acid residue having 3 to 22 carbon atoms, a 3-methyl-2-unsaturated fatty acid residue having 6 to 19 carbon atoms, a 3,4-dimethyl-2-unsaturated fatty acid residue having 7 to 20 carbon atoms, a terpenic acid residue, a 2-amino saturated fatty acid residue having 2 to 18 carbon atoms or a salt thereof, a 2-hydroxy saturated fatty acid residue having 3 to 18 carbon atoms, or a 3,5,5-trimethylhexanoic acid residue.
摘要:
There is provided a heat insulating hose which comprises a seamless cylindrical inner tube formed of a synthetic resin, and a cylindrical heat insulating layer formed of a foamed synthetic resin for covering an outer peripheral face of the inner tube, characterized in that the inner tube is provided at its one end with a cylindrical part for connection with a drain outlet of an air conditioning appliance and formed with a number of ring-shaped protrusion stripes which project toward its outer circumference over an entire length thereof in its axial direction except the cylindrical part spacing a distance W which is wider than an axial width w of each of the ring-shaped protrusion stripes, and that an area b of a desired range spaced by a determined length a from the cylindrical part is an area wherein a number of ring-shaped protrusion stripes are formed at a smaller distance s. Thereby, it is possible to provide a heat insulating hose which can be easily bent at an acute angle for a piping arrangement in a discharging direction such as toward a hole in a wall or the like from a position where it comes out of an air conditioning appliance or the like, and which is not unpleasant in an outer appearance.
摘要:
An ellipticine derivative having the structure: ##STR1## as well as process for the preparation of such ellipticine derivatives. The ellipticine derivatives have antineoplastic or antitumor activity.
摘要:
Two hard steel wire-made reinforcing wires and two synthetic resin wires which are harder than a soft synthetic resin pipe wall are alternately wound spirally on an inner side of the synthetic resin pipe wall while keeping predetermined intervals.
摘要:
The specification discloses a monoclonal antibody capable of distinguishing human hepato-carcinoma cells, a hybridoma producing said monoclonal antibody and a process for preparing the monoclonal antibody using said hybridoma. The monoclonal antibody of the invention specifically attackes hepato-carcinoma cells in vivo.
摘要:
Novel antineoplastic ailanthone derivatives (IIb) represented by the following formula wherein R.sub.2 is C.sub.5 -C.sub.18 .alpha.,.beta.-unsaturated acyl group and its related compounds are disclosed. ##STR1## Particularly, some of the above compounds are far more effective than mitomycin C against mouse lymphocytic leucemia p388.These compounds can be synthesized from known ailanthone via important intermediates, triacyloxy ailanthone, represented by the formula: ##STR2## wherein R.sub.1 is acyl group.
摘要:
A pipe-end-connecting joint comprisse a nipple 1 inserted in the pipe end, a holder 2 for tightening the outer circumference of the pipe end, and an elastic packing 3 divided into half parts and attached in the holder 2. The nipple 1 includes a tubular portion 11 provided in one longitudinal end side thereof so as to be inserted in the pipe end, a connection portion 12 provided in the other longitudinal end side thereof so as to be connected to another joint, and a flange portion 13 provided in a longitudinal intermediate portion thereof so as to protrude outward. The holder 2 is divided longitudinally into two split parts 2A and 2B so that each of the two split parts 2A and 2B has an semicircularly formed inner circumferential surface 21, and each of the two split parts 2A and 2B has one longitudinal end side in which one of the half parts of the elastic packing is mounted, and has the other longitudinal end side in which a ring-like groove 23 is formed so as to be fitted to the flange portion 13, and further has a longitudinally intermediate portion between the one and the other longitudinal end sides in which a spiral corrugated portion 22 is formed along the outer circumferential surface of the pipe P, the spiral corrugated portion 22 having a spiral protruding portion 24 an inner diameter of which is smaller than an outer diameter of a trough portion r of the pipe P, the two split parts 2A and 2B having holes for insertion of connection bolts.