公开(公告)号：US08945177B2

公开(公告)日：2015-02-03

申请号：US13231586

申请日：2011-09-13

申请人： Kent Dell ,  Theodore Ketai ,  Tanmay Mishra ,  Stephanie Jones ,  Jacob Greenberg ,  Michael Hong ,  Daniel Hale ,  Francisco Valencia ,  Steven Tyler

发明人： Kent Dell ,  Theodore Ketai ,  Tanmay Mishra ,  Stephanie Jones ,  Jacob Greenberg ,  Michael Hong ,  Daniel Hale ,  Francisco Valencia ,  Steven Tyler

IPC分类号： A61B17/03 ,  A61B17/08 ,  A61B17/10 ,  A61F2/24 ,  A61B17/00

CPC分类号： A61B17/083 ,  A61B17/08 ,  A61B17/10 ,  A61B2017/00243 ,  A61F2/2454 ,  A61F2/2466

摘要： The invention provides devices, systems and methods for tissue approximation and repair at treatment sites. The devices, systems and methods of the invention will find use in a variety of therapeutic procedures, including endovascular, minimally-invasive, and open surgical procedures, and can be used in various anatomical regions, including the abdomen, thorax, cardiovascular system, heart, intestinal tract, stomach, urinary tract, bladder, lung, and other organs, vessels, and tissues. The invention is particularly useful in those procedures requiring minimally-invasive or endovascular access to remote tissue locations, where the instruments utilized must negotiate long, narrow, and tortuous pathways to the treatment site. In addition, many of the devices and systems of the invention are adapted to be reversible and removable from the patient at any point without interference with or trauma to internal tissues.

摘要翻译： 本发明提供了用于在治疗部位组织近似和修复的装置，系统和方法。 本发明的装置，系统和方法将用于各种治疗方法，包括血管内，微创和开放性外科手术，并可用于各种解剖学领域，包括腹部，胸部，心血管系统，心脏 ，肠道，胃，尿道，膀胱，肺和其他器官，血管和组织。 本发明在需要微创或血管内进入远程组织位置的那些程序中特别有用，其中所使用的仪器必须协商到治疗部位的长，窄和曲折的路径。 此外，本发明的许多装置和系统适于在任何点处可逆地从患者移除，而不会干扰或损伤内部组织。

公开(公告)号：US20130066342A1

公开(公告)日：2013-03-14

申请号：US13231586

申请日：2011-09-13

申请人： Kent Dell ,  Theodore Ketai ,  Tanmay Mishra ,  Stephanie Jones ,  Jacob Greenberg ,  Michael Hong ,  Daniel Hale ,  Francisco Valencia ,  Steven Tyler

发明人： Kent Dell ,  Theodore Ketai ,  Tanmay Mishra ,  Stephanie Jones ,  Jacob Greenberg ,  Michael Hong ,  Daniel Hale ,  Francisco Valencia ,  Steven Tyler

IPC分类号： A61B17/03

CPC分类号： A61B17/083 ,  A61B17/08 ,  A61B17/10 ,  A61B2017/00243 ,  A61F2/2454 ,  A61F2/2466

摘要： The invention provides devices, systems and methods for tissue approximation and repair at treatment sites. The devices, systems and methods of the invention will find use in a variety of therapeutic procedures, including endovascular, minimally-invasive, and open surgical procedures, and can be used in various anatomical regions, including the abdomen, thorax, cardiovascular system, heart, intestinal tract, stomach, urinary tract, bladder, lung, and other organs, vessels, and tissues. The invention is particularly useful in those procedures requiring minimally-invasive or endovascular access to remote tissue locations, where the instruments utilized must negotiate long, narrow, and tortuous pathways to the treatment site. In addition, many of the devices and systems of the invention are adapted to be reversible and removable from the patient at any point without interference with or trauma to internal tissues.

公开(公告)号：US09011468B2

公开(公告)日：2015-04-21

申请号：US13231572

申请日：2011-09-13

申请人： Theodore Ketai ,  Jacob Greenberg ,  Daniel Hale ,  Tanmay Mishra ,  Gabriel Gonzales ,  Raghuveer Basude ,  Michael Hong

发明人： Theodore Ketai ,  Jacob Greenberg ,  Daniel Hale ,  Tanmay Mishra ,  Gabriel Gonzales ,  Raghuveer Basude ,  Michael Hong

IPC分类号： A61B17/08 ,  A61B17/10 ,  A61F2/24 ,  A61B17/00

CPC分类号： A61B17/08 ,  A61B17/10 ,  A61B2017/00243 ,  A61F2/2454 ,  A61F2/2466

摘要： The invention provides devices, systems and methods for tissue approximation and repair at treatment sites. The devices, systems and methods of the invention will find use in a variety of therapeutic procedures, including endovascular, minimally-invasive, and open surgical procedures, and can be used in various anatomical regions, including the abdomen, thorax, cardiovascular system, heart, intestinal tract, stomach, urinary tract, bladder, lung, and other organs, vessels, and tissues. The invention is particularly useful in those procedures requiring minimally-invasive or endovascular access to remote tissue locations, where the instruments utilized must negotiate long, narrow, and tortuous pathways to the treatment site. In addition, many of the devices and systems of the invention are adapted to be reversible and removable from the patient at any point without interference with or trauma to internal tissues.

摘要翻译： 本发明提供了用于在治疗部位组织近似和修复的装置，系统和方法。 本发明的装置，系统和方法将用于各种治疗方法，包括血管内，微创和开放性外科手术，并可用于各种解剖学领域，包括腹部，胸部，心血管系统，心脏 ，肠道，胃，尿道，膀胱，肺和其他器官，血管和组织。 本发明在需要微创或血管内进入远程组织位置的那些程序中特别有用，其中所使用的仪器必须协商到治疗部位的长，窄和曲折的路径。 此外，本发明的许多装置和系统适于在任何点处可逆地从患者移除，而不会干扰或损伤内部组织。

公开(公告)号：US20160103457A1

公开(公告)日：2016-04-14

申请号：US14879322

申请日：2015-10-09

申请人： Steve Maughan ,  Barry C. Loder ,  Wei Fung ,  Daniel Hale ,  William J. Riter

发明人： Steve Maughan ,  Barry C. Loder ,  Wei Fung ,  Daniel Hale ,  William J. Riter

IPC分类号： G05D23/13 ,  G05B19/042

CPC分类号： G05B19/0428 ,  F24F11/00 ,  F24F11/30 ,  F24F11/62 ,  F24F2110/00

摘要： A system for monitoring operational conditions of one or more HVAC units, or other machines, with a plurality of sensors for collecting operational information data and transmitting data to a storage device and a processor for analyzing and trending the data and comparing it to a list of pre-determined set points to determine variances from the data set points and identification of one or more pre-determined events and a set of preventive maintenance alerts and/or troubleshooting instructions pertaining to the events and matching of the preventive maintenance alert and/or troubleshooting instructions to at least one of the events for display of the instructions to a user for resolving the event. The system may utilize a programmable logic array with a portable sensing unit, be capable of monitoring multiple parameters, including temperature, pressure, air flow, voltage, current, and humidity and interconnect to remote stations and SCADA systems.

摘要翻译： 一种用于监视一个或多个HVAC单元或其他机器的操作条件的系统，其具有用于收集操作信息数据并将数据发送到存储设备和处理器的多个传感器，用于分析和趋势化数据并将其与列表 预先确定的设定点，以确定数据设定点的差异和一个或多个预定事件的识别，以及与事件有关的一组预防性维护警报和/或故障排除指令以及预防性维护警报和/或故障排除的匹配 指示用于向用户显示指令以用于解决事件的至少一个事件。 该系统可以利用具有便携式感测单元的可编程逻辑阵列，能够监测多个参数，包括温度，压力，气流，电压，电流和湿度以及与远程站和SCADA系统的互连。

公开(公告)号：US10203676B2

公开(公告)日：2019-02-12

申请号：US14879322

申请日：2015-10-09

申请人： Steve Maughan ,  Barry C. Loder ,  Wei Fung ,  Daniel Hale ,  William J. Riter

发明人： Steve Maughan ,  Barry C. Loder ,  Wei Fung ,  Daniel Hale ,  William J. Riter

IPC分类号： G05B13/00 ,  G05B19/042 ,  F24F11/00 ,  F24F11/30 ,  F24F11/62 ,  F24F110/00

摘要： A system for monitoring operational conditions of one or more HVAC units, or other machines, with a plurality of sensors for collecting operational information data and transmitting data to a storage device and a processor for analyzing and trending the data and comparing it to a list of pre-determined set points to determine variances from the data set points and identification of one or more pre-determined events and a set of preventive maintenance alerts and/or troubleshooting instructions pertaining to the events and matching of the preventive maintenance alert and/or troubleshooting instructions to at least one of the events for display of the instructions to a user for resolving the event. The system may utilize a programmable logic array with a portable sensing unit, be capable of monitoring multiple parameters, including temperature, pressure, air flow, voltage, current, and humidity and interconnect to remote stations and SCADA systems.

公开(公告)号：US07270784B2

公开(公告)日：2007-09-18

申请号：US10837218

申请日：2004-04-30

申请人： Minh Vuong ,  Todd Bennett ,  Javier Flores ,  Brian Grot ,  Daniel Hale ,  Huy Nguyen ,  Walter D. Niles ,  Tuong Phan ,  Steve Rodems ,  Jeff Stack ,  Peter J. Coassin

发明人： Minh Vuong ,  Todd Bennett ,  Javier Flores ,  Brian Grot ,  Daniel Hale ,  Huy Nguyen ,  Walter D. Niles ,  Tuong Phan ,  Steve Rodems ,  Jeff Stack ,  Peter J. Coassin

IPC分类号： G01N21/00 ,  G05B15/00

CPC分类号： G01N35/1074 ,  G01N35/028

摘要： The invention is an automated multiple-purpose, integrated laboratory system comprising interchangeable modular elements for the construction and measurement of biological assays. The functions of the modular elements may include multiwell platform handling, chemical reagent or cell management, volumetric transfer of liquids for assay construction or for recovery of reaction products for analysis, incubation under controlled environmental conditions, measurement of spectrometric signals originating from the assays, processing and analysis of the resulting spectrometric data, and other functions. The modular elements are arranged around a number of robotic elements that deliver plates to different modular elements, transfer plates to groups of modules served by a different robotic element, or other actions necessary in plate handling. Liquid transfer to and from multiwell platforms, necessary for assay construction or for the initiation of physiological events in cells, is partitioned among different modules specialized for transferring nanoliter or smaller volume quantities of chemical concentrates, or microliter quantities of assay reagents, cells, media and other assay constituents. Applications of this invention include the quantitation and analysis of the expression of multiple genes in cells, measurement of multi-gene expression kinetics, analysis of activation or suppression of multiple signal transduction pathways, screening chemical compounds for modulatory effects on multi-gene expression or on signal transduction pathways or on other biochemical networks of cells, or other analytical biological or biochemical assays.

摘要翻译： 本发明是一种自动多功能综合实验室系统，包括用于构建和测量生物测定的可互换模块化元件。 模块化元件的功能可以包括多井平台处理，化学试剂或细胞管理，用于测定构建的液体的体积转移或用于回收用于分析的反应产物，在受控环境条件下孵育，来自测定的光谱信号的测量，处理 并对所得光谱数据进行分析等功能。 模块化元件围绕若干机器人元件布置，其将板递送到不同的模块元件，将板传递到由不同的机器人元件服务的模块组或板处理中所需的其他动作。 液体转移至多孔平台，用于测定结构或细胞中生理事件发生所必需的多孔平台，在专门用于转移纳升或更小体积量的化学浓缩物或微量的测定试剂，细胞，培养基和 其他检测成分。 本发明的应用包括细胞中多个基因的表达的定量和分析，多基因表达动力学的测定，多重信号转导途径的激活或抑制分析，筛选化合物对多基因表达的调节作用或 信号转导途径或细胞的其他生物化学网络或其他分析生物或生物化学测定。

公开(公告)号：US20050054083A1

公开(公告)日：2005-03-10

申请号：US10837218

申请日：2004-04-30

申请人： Minh Vuong ,  Todd Bennett ,  Javier Flores ,  Brian Grot ,  Daniel Hale ,  Huy Nguyen ,  Walter Niles ,  Tuong Phan ,  Steve Rodems ,  Jeff Stack ,  Peter Coassin

发明人： Minh Vuong ,  Todd Bennett ,  Javier Flores ,  Brian Grot ,  Daniel Hale ,  Huy Nguyen ,  Walter Niles ,  Tuong Phan ,  Steve Rodems ,  Jeff Stack ,  Peter Coassin

IPC分类号： B23B27/04 ,  C12M1/34 ,  C12N20060101

CPC分类号： G01N35/1074 ,  G01N35/028

摘要： The invention is an automated multiple-purpose, integrated laboratory system comprising interchangeable modular elements for the construction and measurement of biological assays. The functions of the modular elements may include multiwell platform handling, chemical reagent or cell management, volumetric transfer of liquids for assay construction or for recovery of reaction products for analysis, incubation under controlled environmental conditions, measurement of spectrometric signals originating from the assays, processing and analysis of the resulting spectrometric data, and other functions. The modular elements are arranged around a number of robotic elements that deliver plates to different modular elements, transfer plates to groups of modules served by a different robotic element, or other actions necessary in plate handling. Liquid transfer to and from multiwell platforms, necessary for assay construction or for the initiation of physiological events in cells, is partitioned among different modules specialized for transferring nanoliter or smaller volume quantities of chemical concentrates, or microliter quantities of assay reagents, cells, media and other assay constituents. Applications of this invention include the quantitation and analysis of the expression of multiple genes in cells, measurement of multi-gene expression kinetics, analysis of activation or suppression of multiple signal transduction pathways, screening chemical compounds for modulatory effects on multi-gene expression or on signal transduction pathways or on other biochemical networks of cells, or other analytical biological or biochemical assays.

摘要翻译： 本发明是一种自动多功能综合实验室系统，包括用于构建和测量生物测定的可互换模块化元件。 模块化元件的功能可以包括多井平台处理，化学试剂或细胞管理，用于测定构建的液体的体积转移或用于回收用于分析的反应产物，在受控环境条件下孵育，来自测定的光谱信号的测量，处理 并对所得光谱数据进行分析等功能。 模块化元件围绕若干机器人元件布置，其将板递送到不同的模块元件，将板传递到由不同的机器人元件服务的模块组或板处理中所需的其他动作。 液体转移至多孔平台，用于测定结构或细胞中生理事件发生所必需的多孔平台，在专门用于转移纳升或更小体积量的化学浓缩物或微量的测定试剂，细胞，培养基和 其他检测成分。 本发明的应用包括细胞中多个基因的表达的定量和分析，多基因表达动力学的测定，多重信号转导途径的激活或抑制分析，筛选化合物对多基因表达的调节作用或 信号转导途径或细胞的其他生物化学网络或其他分析生物或生物化学测定。

公开(公告)号：US06641185B2

公开(公告)日：2003-11-04

申请号：US10329901

申请日：2002-12-26

申请人： Daniel Hale ,  Ross Gunn

发明人： Daniel Hale ,  Ross Gunn

IPC分类号： E05C1918

CPC分类号： E05C19/184 ,  Y10T292/37 ,  Y10T292/379 ,  Y10T292/388

摘要： A door locking apparatus for use on a door and an associated door jamb is provided. The door locking apparatus includes a custom striker plate and a U-shaped element or U-Bar. The U-shaped element has two arm portions and the custom striker plate has two arm receiving apertures for receiving the arm portions of the U-shaped element. The U-shaped element partially encircles the shank of a door knob assembly and the two arm portions fit into the two arm receiving apertures to lock the door. A device for keeping the U-shaped element in a locked position is built into the U-shaped element. A preferred embodiment utilizes a notch on the U-shaped element to keep the device in a locked position.

摘要翻译： 提供一种用于门和相关门侧柱的门锁装置。 门锁装置包括定制的撞击板和U形元件或U形杆。 U形元件具有两个臂部分，并且定制的撞击板具有用于接收U形元件的臂部的两个臂接收孔。 U形元件部分地围绕门把手组件的柄部，并且两个臂部分配合到两个臂接收孔中以锁定门。 用于将U形元件保持在锁定位置的装置被内置在U形元件中。 优选实施例利用U形元件上的凹口来将装置保持在锁定位置。