公开(公告)号：US07231253B2

公开(公告)日：2007-06-12

申请号：US10732947

申请日：2003-12-11

申请人： Kevin K. Tidemand ,  Daniel C. Haeg ,  Craig L. Wiklund ,  James F. Kelley ,  Jennifer J. Zhao ,  Andrew J. Ries ,  David C. Rice ,  Hui J. Jin ,  James J. Christenson ,  Loc Van Vo

发明人： Kevin K. Tidemand ,  Daniel C. Haeg ,  Craig L. Wiklund ,  James F. Kelley ,  Jennifer J. Zhao ,  Andrew J. Ries ,  David C. Rice ,  Hui J. Jin ,  James J. Christenson ,  Loc Van Vo

IPC分类号： A61N1/375

CPC分类号： A61N1/375

摘要： An implantable medical device (IMD) includes a connector header for making electrical and mechanical connections with a proximal connector assembly of an electrical medical lead and includes a retainer for retaining a penetrable grommet within a header grommet aperture. A connector block disposed within a header body of the connector header has a threaded bore aligned with a header grommet aperture and a connector block bore aligned with a header connector bore. The penetrable grommet is disposed within the header grommet aperture, and a setscrew is threaded into the threaded bore having a setscrew socket disposed to be engaged by a tool inserted through the penetrable grommet within the header grommet aperture to enable rotation of the setscrew within the threaded bore to tighten the setscrew against or to loosen the setscrew from a lead connector element received in the header connector bore.

摘要翻译： 可植入医疗装置（IMD）包括用于与电气医疗引线的近端连接器组件进行电气和机械连接的连接器插头，并且包括保持器，用于将可穿透的索环保持在头部密封孔内。 设置在连接器插头的插头主体内的连接器块具有与插头孔环孔对准的螺纹孔和与插头连接器孔对准的连接器块孔。 可穿透的索环设置在头部密封孔中，并且固定螺丝被拧入螺纹孔中，该螺纹孔具有固定螺丝插座，该固定螺丝插座设置成由插入到头部孔环孔内的可穿透索环的工具接合，以使固定螺丝能够旋入螺纹 用于将固定螺丝紧固或者从接头插入连接器孔中的引线连接器元件松开固定螺丝。

公开(公告)号：US06205358B1

公开(公告)日：2001-03-20

申请号：US09159119

申请日：1998-09-23

申请人： Daniel C. Haeg ,  Craig L. Wiklund ,  James F. Kelley

发明人： Daniel C. Haeg ,  Craig L. Wiklund ,  James F. Kelley

IPC分类号： A61N1362

CPC分类号： A61N1/375 ,  Y10T29/49174

摘要： The present invention generally relates to implantable medical devices and more particularly to various means for ultrasonically welding, swaging or staking various components in an implantable medical device, most preferably by employing appropriately configured covers or lids. Covers or lids are attached to header or connector modules mounted on an hermetically enclosed and sealed enclosure, where the connector or header module and enclosure comprise an implantable medical device. The covers or lids preferably trap or otherwise secure any of a number of various connector or header module components within the header or connector modules. Examples of such trapped or secured components include grommets, set screw connector blocks, seals, feedthrough wires, multi-beam contacts, electrical contacts, antennas, radio-opaque markers, connector ribbons and the like.

摘要翻译： 本发明总体上涉及可植入医疗装置，更具体地说，涉及用于在植入式医疗装置中超声波焊接，锻压或铆接各种部件的各种装置，最优选地采用适当配置的盖子或盖子。 盖子或盖子连接到安装在密封和密封的外壳上的插头或连接器模块，其中连接器或插头模块和外壳包括可植入的医疗装置。 盖子或盖子优选地捕获或以其他方式固定头部或连接器模块内的多个连接器或头部模块组件中的任何一个。 这种被捕获或固定部件的实例包括垫圈，固定螺钉连接器块，密封件，馈通线，多梁接触件，电触头，天线，不透射线的标记，连接器带等。

公开(公告)号：US5871515A

公开(公告)日：1999-02-16

申请号：US140973

申请日：1998-08-27

申请人： Craig L. Wiklund ,  Daniel C. Haeg ,  James F. Kelley

发明人： Craig L. Wiklund ,  Daniel C. Haeg ,  James F. Kelley

IPC分类号： A61N1/375

CPC分类号： A61N1/3752 ,  Y10T29/49925

摘要： A method and apparatus for attaching a pre-formed header module, e.g. a connector header module or an electrode bearing header module, etc., to a hermetically sealed enclosure of the implantable medical device, typically including electronic integrated circuits, batteries, electromechanical pumps, or the like, are disclosed. A plurality of upstanding tabs that are fixed to the hermetically sealed enclosure, e.g. to the enclosure attachment surface, extend into a like plurality of tab channels formed in the header module housing. The upstanding tab(s) are inserted into the respective tab channel(s) during seating of the module and enclosure attachment surfaces and effects an initial alignment of the header module with the hermetically sealed enclosure. Each attachment tab has a retention feature formed on or in the tab that is designed to accommodate the flow of the thermoplastic material during the application of ultrasonic energy in the region of the tab channel and to cooperate with the solidified mass of thermoplastic material. During application of the ultrasonic energy, the thermoplastic material melts and flows into the remaining space of the tab channel and encapsulate the attachment tab including the retention feature. Upon termination of the ultrasonic energy, the thermoplastic housing material cools and solidifies and forms a continuous mass that encapsulates the surface of the attachment tab and the retention feature.

公开(公告)号：US5871514A

公开(公告)日：1999-02-16

申请号：US904601

申请日：1997-08-01

申请人： Craig L. Wiklund ,  Daniel C. Haeg ,  James F. Kelley

发明人： Craig L. Wiklund ,  Daniel C. Haeg ,  James F. Kelley

IPC分类号： A61N1/375

CPC分类号： A61N1/3752 ,  Y10T29/49925

摘要： A method and apparatus for attaching a pre-formed header module to a hermetically sealed enclosure of an implantable medical device are described. A plurality of upstanding tabs attached to the hermetically sealed enclosure extend into a plurality of corresponding tab channels formed in the header module. The upstanding tabs are inserted into the respective tab channels during seating of the module and enclosure attachment surfaces and effect an initial alignment of the header module with the hermetically sealed enclosure. Each attachment tab has a retention feature such as a recess formed on or in the tab that is designed to receive molten thermoplastic material when ultrasonic energy is applied in the region of the tab channel.

摘要翻译： 描述了一种用于将预成形头部模块附接到可植入医疗装置的密封外壳的方法和装置。 附接到密封外壳的多个直立突出部延伸到形成在头部模块中的多个对应的突舌通道。 在模块和外壳附接表面的座位期间，直立突出部插入到相应的突出部通道中，并实现头部模块与密封外壳的初始对准。 每个附接凸片具有保持特征，例如形成在凸片上或凸片中的凹部，其设计成当超声波能量被施加在凸片通道的区域中时接收熔融的热塑性材料。

公开(公告)号：US5897578A

公开(公告)日：1999-04-27

申请号：US140499

申请日：1998-08-27

申请人： Craig L. Wiklund ,  Daniel C. Haeg ,  James F. Kelley

发明人： Craig L. Wiklund ,  Daniel C. Haeg ,  James F. Kelley

IPC分类号： A61N1/375

CPC分类号： A61N1/3752 ,  Y10T29/49925

摘要： A method and apparatus for attaching a pre-formed header module, e.g. a connector header module or an electrode bearing header module, etc., to a hermetically sealed enclosure of the implantable medical device, typically including electronic integrated circuits, batteries, electromechanical pumps, or the like, are disclosed. A plurality of upstanding tabs that are fixed to the hermetically sealed enclosure, e.g. to the enclosure attachment surface, extend into a like plurality of tab channels formed in the header module housing. The upstanding tab(s) are inserted into the respective tab channel(s) during seating of the module and enclosure attachment surfaces and effects an initial alignment of the header module with the hermetically sealed enclosure. Each attachment tab has a retention feature formed on or in the tab that is designed to accommodate the flow of the thermoplastic material during the application of ultrasonic energy in the region of the tab channel and to cooperate with the solidified mass of thermoplastic material. During application of the ultrasonic energy, the thermoplastic material melts and flows into the remaining space of the tab channel and encapsulate the attachment tab including the retention feature. Upon termination of the ultrasonic energy, the thermoplastic housing material cools and solidifies and forms a continuous mass that encapsulates the surface of the attachment tab and the retention feature.

摘要翻译： 一种用于附接预成形头部模块的方法和装置，例如， 公开了通常包括电子集成电路，电池，机电泵等的可植入医疗装置的气密密封外壳中的连接器插头模块或电极支承插头模块等。 多个直立突出部，固定在密封的外壳上，例如。 到壳体附接表面，延伸到形成在头部模块壳体中的相似的多个突片通道。 在模块和机壳连接表面的座位期间，将直立的插片插入到相应的标签通道中，并且实现了头部模块与密封外壳的初始对准。 每个附接翼片具有形成在翼片上或翼片中的保持特征，该保持特征被设计成在翼片通道的区域中施加超声波能量期间适应热塑性材料的流动并且与固化的热塑性材料块配合。 在施加超声波能量期间，热塑性材料熔化并流入突片通道的剩余空间并且封装包括保持特征的连接片。 在超声波能量终止时，热塑性外壳材料冷却并固化并形成包封附着突片的表面和保持特征的连续质量。

公开(公告)号：US07187974B2

公开(公告)日：2007-03-06

申请号：US10199601

申请日：2002-07-19

申请人： Daniel C. Haeg ,  Craig L. Wiklund ,  James F. Kelley

发明人： Daniel C. Haeg ,  Craig L. Wiklund ,  James F. Kelley

IPC分类号： A61N1/375

CPC分类号： A61N1/375

摘要： The present invention generally relates to an improved implantable medical device (IMD) and more particularly to an ultrasonically weld perforated lid for an IMD to form a hermetic seal between the IMD and the perforated lid. Appropriately configured perforated lids retain one or more components within a cavity or port formed in a part of an IMD. Such lids preferably secure a pierceable resilient grommet, septum or other resilient member in a cavity or port. When an adjustment instrument, a pull tool or a syringe is temporarily inserted therethrough and later extracted, the resilient member heals (i.e., seals and/or reseals). Preferably, the resilient member abuts a mechanical stop and is compressed slightly during assembly and ultrasonic welding of the lid. The resilient member preferably has a lateral dimension like the cavity or port so that when the lid compresses the resilient member it expands slightly and contacts the interior cavity surfaces thus improving the seal.

摘要翻译： 本发明总体上涉及一种改进的可植入医疗装置（IMD），更具体地涉及用于IMD的超声波焊接多孔盖，以在IMD和多孔盖之间形成气密密封。 适当配置的穿孔盖在IMD的一部分中形成的腔或端口内保留一个或多个部件。 这种盖子优选地将可刺破的弹性垫圈，隔膜或其它弹性构件固定在空腔或端口中。 当调节工具，拉动工具或注射器临时插入其中并随后抽出时，弹性部件愈合（即，密封和/或回收）。 优选地，弹性构件邻接机械止动件并且在盖的组装和超声波焊接期间被稍微压缩。 优选地，弹性构件具有类似于腔或端口的侧向尺寸，使得当盖子压缩弹性构件时，其稍微膨胀并与内腔表面接触，从而改善密封。

公开(公告)号：US5919215A

公开(公告)日：1999-07-06

申请号：US140969

申请日：1998-08-27

申请人： Craig L. Wiklund ,  Daniel C. Haeg ,  James F. Kelley

发明人： Craig L. Wiklund ,  Daniel C. Haeg ,  James F. Kelley

IPC分类号： A61N1/375

CPC分类号： A61N1/3752 ,  Y10T29/49925

摘要： A method and apparatus for attaching a pre-formed header module, e.g. a connector header module or an electrode bearing header module, etc., to a hermetically sealed enclosure of the implantable medical device, typically including electronic integrated circuits, batteries, electromechanical pumps, or the like, are disclosed. A plurality of upstanding tabs that are fixed to the hermetically sealed enclosure, e.g. to the enclosure attachment surface, extend into a like plurality of tab channels formed in the header module housing. The upstanding tab(s) are inserted into the respective tab channel(s) during seating of the module and enclosure attachment surfaces and effects an initial alignment of the header module with the hermetically sealed enclosure. Each attachment tab has a retention feature formed on or in the tab that is designed to accommodate the flow of the thermoplastic material during the application of ultrasonic energy in the region of the tab channel and to cooperate with the solidified mass of thermoplastic material. During application of the ultrasonic energy, the thermoplastic material melts and flows into the remaining space of the tab channel and encapsulate the attachment tab including the retention feature. Upon termination of the ultrasonic energy, the thermoplastic housing material cools and solidifies and forms a continuous mass that encapsulates the surface of the attachment tab and the retention feature.

摘要翻译： 一种用于附接预成形头部模块的方法和装置，例如， 公开了通常包括电子集成电路，电池，机电泵等的可植入医疗装置的气密密封外壳中的连接器插头模块或电极支承插头模块等。 多个直立突出部，固定在密封的外壳上，例如。 到壳体附接表面，延伸到形成在头部模块壳体中的相似的多个突片通道。 在模块和机壳连接表面的座位期间，将直立的插片插入到相应的标签通道中，并且实现了头部模块与密封外壳的初始对准。 每个附接翼片具有形成在翼片上或翼片中的保持特征，该保持特征被设计成在翼片通道的区域中施加超声波能量期间适应热塑性材料的流动并且与固化的热塑性材料块配合。 在施加超声波能量期间，热塑性材料熔化并流入突片通道的剩余空间并且封装包括保持特征的连接片。 在超声波能量终止时，热塑性外壳材料冷却并固化并形成包封附着突片的表面和保持特征的连续质量。

公开(公告)号：US08409219B2

公开(公告)日：2013-04-02

申请号：US12570390

申请日：2009-09-30

申请人： James F. Kelley ,  Zhongping C. Yang ,  Mark T. Stewart

发明人： James F. Kelley ,  Zhongping C. Yang ,  Mark T. Stewart

IPC分类号： A61B19/00

CPC分类号： A61N1/059 ,  A61B17/12 ,  A61B17/12009 ,  A61B17/128 ,  A61B17/3468 ,  A61B2017/00247 ,  A61B2017/12018 ,  A61B2018/00392

摘要： A method of placing an electrical lead of an implantable cardiac device inside a heart of a patient. The method includes securing a tool to an atrial appendage of the heart to hold onto the atrial appendage, piercing the atrial appendage, and creating an aperture in the atrial appendage while holding the atrial appendage with the tool. The method also includes moving a distal end of the electrical lead into the heart through the aperture in the atrial appendage and into a ventricle of the heart. Furthermore, the method includes coupling the distal end of the electrical lead to cardiac tissue in the ventricle and delivering an electrical signal to the cardiac tissue in the ventricle of the heart to maintain a predetermined heartbeat of the heart.

摘要翻译： 将可植入心脏装置的电引线放置在患者心脏内的方法。 该方法包括将工具固定到心脏的心房附着物，以固定在心房附近，刺穿心房附件，以及在用该工具持有心房附件的同时创建心房附近的孔。 该方法还包括通过心耳中的孔将电引线的远端移动到心脏中并进入心脏的心室。 此外，该方法包括将电导线的远端耦合到心室中的心脏组织，并将电信号传送到心脏心室的心脏组织以维持心脏的预定心跳。

公开(公告)号：US06836687B2

公开(公告)日：2004-12-28

申请号：US10131388

申请日：2002-04-25

申请人： James F. Kelley ,  James H. Vaughn ,  Stanten C. Spear ,  Douglas S. Hine ,  Kenneth C. Gardeski ,  Vicki L. Bjorklund ,  Pedro A. Meregotte ,  John L. Sommer ,  John J. Maier

发明人： James F. Kelley ,  James H. Vaughn ,  Stanten C. Spear ,  Douglas S. Hine ,  Kenneth C. Gardeski ,  Vicki L. Bjorklund ,  Pedro A. Meregotte ,  John L. Sommer ,  John J. Maier

IPC分类号： A61N105

CPC分类号： A61M25/0138 ,  A61B18/1492 ,  A61B2017/22038 ,  A61M25/005 ,  A61M25/0054 ,  A61M25/0141 ,  A61M25/0147 ,  A61M25/0668 ,  A61M39/0613 ,  A61M2025/0042 ,  A61M2025/0047 ,  A61M2025/0081 ,  A61M2025/0161 ,  A61M2025/0681 ,  A61M2025/1052 ,  A61M2025/1079 ,  A61N1/05 ,  A61N1/056 ,  A61N2001/0578 ,  A61N2001/0585

摘要： A system for delivering a medical electrical lead within a coronary venous system that includes an introducer kit for establishing venous access to the coronary venous system and a plurality of delivery sheaths, each corresponding to a desired approach to a coronary sinus of the coronary venous system and insertable within the coronary venous system through the navigation pathway. A hemostasis valve is coupled to a delivery sheath of the plurality of delivery sheaths, and a guide wire is inserted within the lead lumen, guiding delivery of the distal tip of the medical electrical lead to a target site within the coronary venous system through the hemostasis valve and the delivery sheath. Subsequent to the distal tip being delivered to the target sight, the hemostasis valve is advanced over the connector of the medical electrical lead to remove the hemostasis valve from the medical electrical lead.

摘要翻译： 一种用于在冠状静脉系统内递送医用电线的系统，其包括用于建立对冠状静脉系统的静脉通路的引导器套件和多个输送护套，每个输送护套对应于冠状静脉系统的冠状窦所需的方法， 通过导航路径插入冠状静脉系统内。 止血阀联接到多个输送护套的输送护套，并且引导线插入引导腔内，通过止血将医用电导线的远端引导到冠状静脉系统内的靶位点 阀门和输送护套。 在远端尖端被传送到目标瞄准器之后，止血阀在医用电线的连接器上前进，以从医用电引线上除去止血阀。

公开(公告)号：US5282466A

公开(公告)日：1994-02-01

申请号：US770672

申请日：1991-10-03

申请人： Timothy J. Duffy ,  Ralph M. Kerns ,  James F. Kelley ,  Eric J. Fogt

发明人： Timothy J. Duffy ,  Ralph M. Kerns ,  James F. Kelley ,  Eric J. Fogt

IPC分类号： A61B5/00 ,  G01N21/27

CPC分类号： A61B5/14535 ,  A61B5/14557 ,  A61B5/1495 ,  G01N21/274 ,  A61B2560/0233 ,  G01N2201/1244 ,  G01N2201/1281

摘要： A system for disabling an oximetric device when radiation-carrying channels are exposed to excess ambient radiation is disclosed. It includes a transmitter channel adjacent the sample to be measured, means for isolating the channel from the sample so that it does not carry radiation reflected from or transmitted through the sample, a detector for receiving the transmitted signal, if any, and means for disabling the output in response to the transmitted signal. Preferably, the transmitter channel runs parallel to other transmitter channels in the device, and is isolated from undue ambient light. The system preferably includes means for determining when the second transmitted signal exceeds background noise and the output is disabled when the second transmitted signal exceeds background noise. In general, the sample is a fluid, usually blood, passing through a cuvette adjacent the fiber-optic channels, the cuvette defining an area of radiation absorption adjacent the transmitter channel so that the transmitter does not carry reflected or transmitted radiation from the sample. Also disclosed is a fiber-optic sensor for measuring components of a composition by detecting transmitted or reflected, usually reflected, radiation including such a system, and the cuvette therefore. Finally, a method of disabling the output of an oximetric device when the fiber-optic channels are exposed to undue ambient radiation is disclosed.