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24 条记录 (耗时 0.021 秒)

    Process for the conversion of pitch into crystalloidal pitch
    5.
    发明授权
    Process for the conversion of pitch into crystalloidal pitch 失效
    沥青转化为晶体间距的工艺

    公开(公告)号：US4042486A

    公开(公告)日：1977-08-16

    申请号：US665620

    申请日：1976-03-10

    申请人： Kiro Asano ,  Humio Tamura ,  Tsuyoshi Saito ,  Yoshio Kawai

    发明人： Kiro Asano ,  Humio Tamura ,  Tsuyoshi Saito ,  Yoshio Kawai

    IPC分类号： C01B31/00 ,  C04B35/528 ,  C10C3/14 ,  C10C3/00

    CPC分类号： C10C3/14 ,  C01B31/00 ,  C04B35/528

    摘要： Crystalloidal pitch is obtained by subjecting solid pitch particles measuring not more than 5 mm in cross-sectional equivalent diameter to a treatment to prevent cohesion and subsequently bringing the cohesion-proof solid pitch particles into contact with a non-oxidative gas at temperatures of from 350.degree. C to 550.degree. C while maintaining a gas flow rate sufficient to provide a suspension wherein the gas constitutes at least 30% by volume. The crystalloid pitch is useful as a precursor for various carbon products.

    摘要翻译： 晶体间距是通过将具有截面当量直径的不超过5mm的固体沥青颗粒进行处理以防止内聚力并随后使内聚力固体沥青颗粒与非氧化性气体在350℃ ℃至550℃，同时保持足以提供悬浮液的气体流速，其中气体构成至少30体积％。 晶体间距可用作各种碳产品的前体。

    Estradiol derivative-chlorambucil conjugate process for preparing the same, and pharmaceutical composition
    6.
    发明授权
    Estradiol derivative-chlorambucil conjugate process for preparing the same, and pharmaceutical composition 失效
    雌二醇衍生物 - 苯丁酸氮芥与其制备方法及药物组合物

    公开(公告)号：US5354745A

    公开(公告)日：1994-10-11

    申请号：US070797

    申请日：1993-06-03

    申请人： Fumio Tamura ,  Tsuyoshi Saito ,  Satoshi Mitsuhashi ,  Tadahiro Matsudaira ,  Kiro Asano

    发明人： Fumio Tamura ,  Tsuyoshi Saito ,  Satoshi Mitsuhashi ,  Tadahiro Matsudaira ,  Kiro Asano

    IPC分类号： A61K31/575 ,  A61P35/00 ,  A61P37/06 ,  C07J1/00 ,  C07J41/00

    CPC分类号： C07J1/0074 ,  C07J1/007 ,  C07J41/0072

    摘要： An estradiol derivative-chlorambucil conjugate of the formula (I): ##STR1## wherein R.sup.1 is alkyl or alkoxyl of 1 to 4 carbon atoms; R.sup.2 is acyl, dansyl, or alkyl; R.sup.3, R.sup.4, and R.sup.5 independently are H, oxo, OH, or acyloxy; m is an integer of 1 to 3; and n is an integer of 0 to 3; provided that when n is 0, all of R.sup.3, R.sup.4, and R.sup.5 are not H at the same time, and at least one of R.sup.3, R.sup.4, and R.sup.5 is a group other than H and OH; and further, when n is 2 or 3, the groups R.sup.1 are the same or different; a process for preparing the same, and a pharmaceutical composition containing the conjugate are described.

    摘要翻译： 式（I）的雌二醇衍生物 - 苯丁酸氮芥共轭物：其中R 1是1至4个碳原子的烷基或烷氧基; R2是酰基，丹磺酰基或烷基; R3，R4和R5独立地是H，氧代，OH或酰氧基; m为1〜3的整数。 n为0〜3的整数。 条件是当n为0时，R3，R4和R5全部同时不为H，R3，R4和R5中的至少一个为除H和OH以外的基团; 此外，当n为2或3时，基团R 1相同或不同; 描述了制备该共轭物的方法和含有该缀合物的药物组合物。

    Method for suppressing an immunoresponse with an estradiol derivative-chlorambucil conjugate
    7.
    发明授权
    Method for suppressing an immunoresponse with an estradiol derivative-chlorambucil conjugate 失效
    用雌二醇衍生物 - 苯丁酸氮芥配偶体抑制免疫应答的方法

    公开(公告)号：US5578589A

    公开(公告)日：1996-11-26

    申请号：US440838

    申请日：1995-05-15

    申请人： Fumio Tamura ,  Tsuyoshi Saito ,  Satoshi Mitsuhashi ,  Tadahiro Matsudaira ,  Kiro Asano

    发明人： Fumio Tamura ,  Tsuyoshi Saito ,  Satoshi Mitsuhashi ,  Tadahiro Matsudaira ,  Kiro Asano

    IPC分类号： A61K31/575 ,  A61P35/00 ,  A61P37/06 ,  C07J1/00 ,  C07J41/00 ,  A61K31/56

    CPC分类号： C07J1/0074 ,  C07J1/007 ,  C07J41/0072

    摘要： The invention is drawn to a method for suppressing an immunoresponse in animals by administering an estradiol derivative-chlorambucil conjugate of the formula (I): ##STR1## wherein R.sup.1 is alkyl or alkoxyl of 1 to 4 carbon atoms; R.sup.2 is acyl, dansyl, or alkyl; R.sup.3, R.sup.4, and R.sup.5 independently are H, oxo, OH, or acyloxy; m is an integer of 1 to 3; and n is an integer of 0 to 3; provided that when n is 0, all of R.sup.3, R.sup.4, and R.sup.5 are not H at the same time, and at least one of R.sup.3, R.sup.4, and R.sup.5 is a group other than H and OH; and further, when n is 2 or 3, the groups R.sup.1 are the same or different.

    摘要翻译： 本发明涉及一种通过给予式（I）的雌二醇衍生物 - 苯丁酸氮芥配偶体来抑制动物免疫反应的方法：其中R1是1-4个碳原子的烷基或烷氧基; R2是酰基，丹磺酰基或烷基; R3，R4和R5独立地是H，氧代，OH或酰氧基; m为1〜3的整数。 n为0〜3的整数。 条件是当n为0时，R3，R4和R5全部同时不为H，R3，R4和R5中的至少一个为除H和OH以外的基团; 此外，当n为2或3时，基团R 1相同或不同。

    Process for preparing trans-4-aminomethyl-cyclohexane-1-carboxylic acid
    8.
    发明授权
    Process for preparing trans-4-aminomethyl-cyclohexane-1-carboxylic acid 失效
    制备反式-4-氨基甲基 - 环己烷-1-羧酸的方法

    公开(公告)号：US4048222A

    公开(公告)日：1977-09-13

    申请号：US447794

    申请日：1974-03-04

    申请人： Tsuyoshi Saito ,  Kiro Asano

    发明人： Tsuyoshi Saito ,  Kiro Asano

    IPC分类号： C07C99/00

    CPC分类号： C07C229/28

    摘要： A process for preparing trans-4-aminomethylcyclohexane-1-carboxylic acid which comprises catalytically reducing p-aminomethylbenzoic acid or a derivative thereof in the presence of a ruthenium catalyst in a solution of a strong acid or a strong alkali as a solvent is disclosed.

    摘要翻译： 公开了一种制备反式-4-氨基甲基环己烷-1-羧酸的方法，其包括在强酸或强碱溶剂作为溶剂的钌催化剂存在下催化还原对氨基甲基苯甲酸或其衍生物。

    Method for producing solid carbon material having high flexural strength
    9.
    发明授权
    Method for producing solid carbon material having high flexural strength 失效
    具有高弯曲强度的固体碳材料的制造方法

    公开(公告)号：US4293533A

    公开(公告)日：1981-10-06

    申请号：US758838

    申请日：1977-01-12

    申请人： Kiro Asano ,  Humio Tamura ,  Yushi Nezu ,  Tsuyoshi Saito ,  Yoshio Kawai

    发明人： Kiro Asano ,  Humio Tamura ,  Yushi Nezu ,  Tsuyoshi Saito ,  Yoshio Kawai

    IPC分类号： C01B31/02 ,  C01B31/00 ,  C01B31/04 ,  C04B35/52 ,  D01F9/145 ,  D01F9/155

    CPC分类号： D01F9/155 ,  C01B31/00 ,  C04B35/52 ,  D01F9/145

    摘要： Solid carbon material having extremely high flexural strength can be produced by introducing a sufficient amount of functional group to satisfy the undernoted general equation into a pitch having a H/C atomic ratio of 0.8 at most, thereby obtaining precursory carbon material; shaping said precursory carbon material into a desired article without using any binding material; and carbonizing or further graphitizing said article; wherein the general equation is ##EQU1## where, H/C is the hydrogen-to-carbon atomic ratio of the pitch, R is a numeral ranging from 0.2 to 0.3, and f is the percent by weight of at least one of oxygen, sulfur and halogen contained in the total functional groups introduced into the precursory carbon material on the basis of the weight thereof.

    摘要翻译： 可以通过将足够量的官能团引入足够的一般方程式至最高H / C原子比为0.8的间距，从而获得前体碳材料，从而制得具有极高弯曲强度的固体碳材料。 将所述前体碳材料成型为期望的制品，而不使用任何粘合材料; 并且碳化或进一步石墨化所述制品; 其中一般方程式是其中H / C是间距的氢 - 碳原子比，R是0.2-0.3的数字，f是氧中的至少一种的重量百分数， 基于其重量，引入前体碳材料的总官能团中所含的硫和卤素。