Diagnostic method for inflammatory conditions in the intestines
    1.
    发明授权
    Diagnostic method for inflammatory conditions in the intestines 有权
    肠道炎症状况的诊断方法

    公开(公告)号:US06183416B2

    公开(公告)日:2001-02-06

    申请号:US09273514

    申请日:1999-03-22

    IPC分类号: A61B500

    摘要: Method for diagnosis of inflammatory conditions in the intestinal canal of humans, characterized in that NO is measured in the lumen of the intestines. The NO level obtained is then compared with the level obtained for healthy individuals or with the level obtained for the same individual at another occasion. An increased level compared to the normal levels in the intestines of the healthy population is an indication of an inflammatory condition in the intestine.

    摘要翻译: 用于诊断人体肠道炎症状况的方法,其特征在于在肠腔内测量NO。 然后将获得的NO水平与对于健康个体获得的水平或在另一时间为相同个体获得的水平进行比较。 与健康人群的肠道正常水平相比,增加了肠道炎症状态。

    Ventilator device
    2.
    发明授权
    Ventilator device 失效
    呼吸机装置

    公开(公告)号:US06308703B1

    公开(公告)日:2001-10-30

    申请号:US09292598

    申请日:1999-04-16

    IPC分类号: A61M1500

    摘要: The present invention restores the normal low-dose flushing of the lower airways with air from the upper airways, containing nitric oxide (NO) and possible other biologically active agents by aspiration of air from the upper airways and introducing said air in the inspiratory airflow of a ventilator. The inventive apparatus and method is free from the risks associated with traditional administration of exogenous NO.

    摘要翻译: 本发明通过从上呼吸道吸入空气从上呼吸道的空气中回收含有一氧化氮(NO)和可能的其它生物活性剂的下气道的正常低剂量冲洗,并将所述空气在吸气气流中引入 一个呼吸机 本发明的装置和方法没有与传统给药外源NO相关的风险。

    Method and device for use in the diagnosis of inflammatory states in the
urogenital tract
    3.
    发明授权
    Method and device for use in the diagnosis of inflammatory states in the urogenital tract 失效
    用于诊断泌尿生殖道炎症状态的方法和装置

    公开(公告)号:US6149606A

    公开(公告)日:2000-11-21

    申请号:US156000

    申请日:1998-12-08

    IPC分类号: A61B10/00 A61B5/00 G01N33/497

    摘要: Device and method for collecting endogenous gaseous nitric oxide (NO), in the urogenital tract, for example in the urinary tract and in the uterus and oviducts. According to one embodiment, a NO permeable, liquid impermeable inflatable body (16) is positioned in the urethra (5) surrounded by the prostate gland (17), whereby an additional inflatable body (4) positioned in the bladder (2) serves to seal off the bladder from the urethra and helps in the positioning of the device. The present invention further relates to a method and a system for use in the diagnosis of inflammatory states in said organs.

    摘要翻译: PCT No.PCT / SE97 / 00610 Sec。 371日期1998年12月8日第 102(e)日期1998年12月8日PCT 1997年4月11日PCT PCT。 公开号WO97 / 37587 日期1997年10月16日在泌尿生殖道中,例如在尿道和子宫和输卵管中收集内源性一氧化氮(NO)的装置和方法。 根据一个实施例,NO渗透的液体不可渗透的可充气体(16)定位在由前列腺(17)包围的尿道(5)中,由此定位在囊(2)中的另外的可充气体(4)用于 从尿道密封膀胱,有助于设备的定位。 本发明还涉及用于诊断所述器官中炎性状态的方法和系统。

    Diagnostic method for inflammatory conditions in the intestines
    4.
    发明授权
    Diagnostic method for inflammatory conditions in the intestines 失效
    肠道炎症状况的诊断方法

    公开(公告)号:US6063027A

    公开(公告)日:2000-05-16

    申请号:US849282

    申请日:1997-05-30

    摘要: Method for diagnosis of inflammatory conditions in the intestinal canal of humans, characterized in that NO is measured in the lumen of the intestines. The NO level obtained is then compared with the level obtained for healthy individuals or with the level obtained for the same individual at another occasion. An increased level compared to the normal levels in the intestines of the healthy population is an indication of an inflammatory condition in the intestine.

    摘要翻译: PCT No.PCT / SE95 / 01429 Sec。 371日期1997年5月30日 102(e)日期1997年5月30日PCT提交1995年11月29日PCT公布。 公开号WO96 / 17244 日期1996年6月6日诊断人肠道炎症状况的方法,其特征在于在肠腔内测量NO。 然后将获得的NO水平与对于健康个体获得的水平或在另一时间为相同个体获得的水平进行比较。 与健康人群的肠道正常水平相比,增加了肠道炎症状态。

    Device for the collection, storage and/or transport of gas samples
    6.
    发明授权
    Device for the collection, storage and/or transport of gas samples 有权
    用于采集,储存和/或运输气体样品的装置

    公开(公告)号:US06723056B1

    公开(公告)日:2004-04-20

    申请号:US09688860

    申请日:2000-10-17

    IPC分类号: A61B500

    摘要: A gas sample containing an inorganic constituent, such as a sample of exhaled air is collected in a bag (b 1) comprising an inlet/outlet (2) and a reagent chamber (3) which makes possible the storage and transport of said sample and thus enables efficient and repeatable off-line determinations of inorganic components in said sample. A sample collection device, a system comprising said device and a method of its use is disclosed.

    摘要翻译: 含有无机成分(如呼出空气样品)的气体样品被收集在包括入口/出口(2)和试剂室(3)的袋子(b 1)中,所述袋子(2)和试剂室(3)使得所述样品的储存和运输成为可能, 从而能够对所述样品中的无机组分进行有效和可重复的离线测定。 公开了一种样品收集装置,包括所述装置的系统及其使用方法。

    Method and composition for inhibition of nitric oxide production in the oral cavity
    7.
    发明授权
    Method and composition for inhibition of nitric oxide production in the oral cavity 有权
    抑制口腔一氧化氮生成的方法和组成

    公开(公告)号:US06626844B1

    公开(公告)日:2003-09-30

    申请号:US09601289

    申请日:2000-09-01

    IPC分类号: A61B500

    CPC分类号: G01N33/497

    摘要: The disturbing influence or orally produced nitric oxide in the measuring of exhaled nitric oxide can be ameliorated or totally eliminated through the use of a method and composition according to the present invention. The production of NO in the oral cavity is temporarily inhibited by the application of a composition having anti-bacterial and/or pH increasing effect.

    摘要翻译: 通过使用根据本发明的方法和组合物可以改善或完全消除呼出一氧化氮测量中的干扰影响或口服产生的一氧化氮。 通过施用具有抗菌和/或pH增加效果的组合物,临时抑制口腔内产生NO。

    System to be used for the determination of no levels in exhaled air and
diagnostic methods for disorders related to abnormal no levels
    9.
    发明授权
    System to be used for the determination of no levels in exhaled air and diagnostic methods for disorders related to abnormal no levels 失效
    用于确定呼出空气中无水平的系统和与异常无关的疾病的诊断方法

    公开(公告)号:US5922610A

    公开(公告)日:1999-07-13

    申请号:US578653

    申请日:1996-01-05

    摘要: The present invention is drawn to a system to be used for measuring NO levels in exhaled breathing air. The system comprises: (i) a face mask that tightly covers the nose and/or mouth of the individual that the mask is intended to be used on; (ii) an inlet unit for inhaled breathing air, (iii) an outlet unit for exhaled breathing air, (iv) a non-rebreathing valve through which inhaled and exhaled breathing air, respectively, passes, and (v) a measuring unit for NO connected to the outlet unit. The present invention furthers encompasses a method for the diagnosis in mammals of inflammatory conditions in the airways. The characteristic feature is that nitric oxide NO is measured in exhaled breathing air and a found abnormal level is taken as an indication of an inflammatory condition in the airways.

    摘要翻译: PCT No.PCT / SE94 / 00659 Sec。 371日期1996年1月5日 102(e)日期1996年1月5日PCT提交1994年7月4日PCT公布。 WO95 / 02181 PCT出版物 日期1995年1月19日本发明涉及用于测量呼出呼吸空气中的NO水平的系统。 所述系统包括:(i)紧密地覆盖所述个人的鼻子和/或口部的口罩,所述口罩旨在用于所述面罩; (ii)用于吸入呼吸空气的入口单元,(iii)用于呼出呼吸空气的出口单元,(iv)分别吸入和呼出的呼吸空气通过的非再呼吸阀,以及(v)用于 NO连接到出口单元。 本发明进一步包括用于在哺乳动物中诊断气道中的炎性病症的方法。 其特征是在呼出呼吸空气中测量一氧化氮NO,发现异常水平作为气道炎症状态的指标。