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公开(公告)号:US5059520A
公开(公告)日:1991-10-22
申请号:US900820
申请日:1986-08-27
申请人: Koichi Furukawa , Hanrik Clausen , Sen-itiroh Hakomori , Junichi Sakamoto , Katherine Look , M. Jules Mattes , Lloyd Kenneth O.
发明人: Koichi Furukawa , Hanrik Clausen , Sen-itiroh Hakomori , Junichi Sakamoto , Katherine Look , M. Jules Mattes , Lloyd Kenneth O.
IPC分类号: C07K16/30 , C07K16/34 , G01N33/574 , G01N33/80
CPC分类号: C07K16/30 , C07K16/34 , G01N33/574 , G01N33/57469 , G01N33/80 , G01N2333/705 , Y10S436/811 , Y10S436/813
摘要: Monoconal antibodies HT29-36, CB, CLH6, M2, and S12 are useful in determining the presence of Type A blood group antigen and in distinguishing different forms of this antigen. As type A antigen exhibits several forms differing in minor respects only, the monoclonal antibodies are useful in making fine distinctions between the different forms, and may be used, e.g., in cancer diagnosis, and the like.
摘要翻译: 单克隆抗体HT29-36,CB,CLH6,M2和S12可用于确定A型血型抗原的存在和区分该抗原的不同形式。 由于A型抗原仅在少数方面表现出几种形式,所以单克隆抗体可用于在不同形式之间进行细微区分,并且可用于例如癌症诊断等。
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2.
公开(公告)号:US4863854A
公开(公告)日:1989-09-05
申请号:US764862
申请日:1985-08-12
IPC分类号: G01N33/574 , A61K39/395 , C07K14/005 , C07K14/195 , C07K14/435 , C07K16/00 , C07K16/30 , C12N5/10 , C12N15/02 , C12P21/08 , C12R1/91 , G01N33/577
CPC分类号: C07K16/30 , Y10S436/813 , Y10S530/828 , Y10S530/844 , Y10S530/864
摘要: Three new monoclonal antibodies, MU78, MT334, and MQ49, and the hybridoma cell lines producing these, are disclosed. The antibodies specifically bind to mucin-like antigens with distribution over various carcinomas.
摘要翻译: 公开了三种新的单克隆抗体MU78,MT334和MQ49以及产生这些的杂交瘤细胞系。 抗体特异性结合粘蛋白样抗原,分布在各种癌上。
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