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1.发明申请METHOD FOR PROMOTING IMMUNOTHERAPY USING AN AGENT FOR ELEVATING DENDRITIC CELL PRECURSOR LEVEL IN BLOOD 审中-公开促进免疫功能的方法，用于增加血液中的细胞前体水平公开(公告)号：US20100021442A1
公开(公告)日：2010-01-28
申请号：US12554676
申请日：2009-09-04
CPC分类号： A61K38/195
摘要： Although the fields of therapeutic applications of dendritic cells are now expanding, dendritic cell precursors exist only in a small amount in the peripheral blood and, therefore, it is still difficult to obtain them in a therapeutically useful amount even though they are proliferated in vitro. Therefore, it is a key point in performing a therapy with the use of dendritic cells in practice to elevate dendritic cell precursor level in the peripheral blood of a patient. The present invention provides an agent for elevating dendritic cell precursor level in the blood which comprises an agonist to a receptor expressed in immature dendritic cells or a functional derivative thereof as the active ingredient.
摘要翻译： 尽管树突状细胞的治疗应用领域现在正在扩大，但是树突状细胞前体在外周血中仅存在少量，因此即使体外增殖，仍然难以以治疗有用的量获得它们。 因此，在实践中使用树突状细胞进行治疗是关键点，以提高患者外周血中的树突状细胞前体水平。 本发明提供了一种用于提高血液中树突状细胞前体水平的试剂，其包含对未成熟树突状细胞中表达的受体的激动剂或其功能性衍生物作为活性成分。
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公开(公告)号：US20060210531A1
公开(公告)日：2006-09-21
申请号：US10531580
申请日：2003-10-21
CPC分类号： A61K38/195
摘要： Although the fields of therapeutic applications of dendritic cells are now expanding, dendritic cell precursors exist only in a small amount in the peripheral blood and, therefore, it is still difficult to obtain them in a therapeutically useful amount even though they are proliferated in vitro. Therefore, it is a key point in performing a therapy with the use of dendritic cells in practice to elevate dendritic cell precursor level in the peripheral blood of a patient. The present invention provides an agent for elevating dendritic cell precursor level in the blood which comprises an agonist to a receptor expressed in immature dendritic cells or a functional derivative thereof as the active ingredient.
摘要翻译： 尽管树突状细胞的治疗应用领域现在正在扩大，但是树突状细胞前体在外周血中仅存在少量，因此即使体外增殖，仍然难以以治疗有用的量获得它们。 因此，在实践中使用树突状细胞进行治疗是关键点，以提高患者外周血中的树突状细胞前体水平。 本发明提供了一种用于提高血液中树突状细胞前体水平的试剂，其包含对未成熟树突状细胞中表达的受体的激动剂或其功能性衍生物作为活性成分。
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公开(公告)号：US20080124307A1
公开(公告)日：2008-05-29
申请号：US11819147
申请日：2007-06-25
CPC分类号： A61K38/195
摘要： Although the fields of therapeutic applications of dendritic cells are now expanding, dendritic cell precursors exist only in a small amount in the peripheral blood and, therefore, it is still difficult to obtain them in a therapeutically useful amount even though they are proliferated in vitro. Therefore, it is a key point in performing a therapy with the use of dendritic cells in practice to elevate dendritic cell precursor level in the peripheral blood of a patient. The present invention provides an agent for elevating dendritic cell precursor level in the blood which comprises an agonist to a receptor expressed in immature dendritic cells or a functional derivative thereof as the active ingredient.
摘要翻译： 尽管树突状细胞的治疗应用领域现在正在扩大，但是树突状细胞前体在外周血中仅存在少量，因此即使体外增殖，仍然难以以治疗有用的量获得它们。 因此，在实践中使用树突状细胞进行治疗是关键点，以提高患者外周血中的树突状细胞前体水平。 本发明提供了一种用于提高血液中树突状细胞前体水平的试剂，其包含对未成熟树突状细胞中表达的受体的激动剂或其功能性衍生物作为活性成分。
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公开(公告)号：US09064836B1
公开(公告)日：2015-06-23
申请号：US12852643
申请日：2010-08-09
申请人： Chin-Tien Chiu , Shrikar Bhagath , Yuang Zhang , Lu Zhong , Kaiyou Qian
发明人： Chin-Tien Chiu , Shrikar Bhagath , Yuang Zhang , Lu Zhong , Kaiyou Qian
CPC分类号： H01L29/34 , B24B7/228 , B24B37/107 , H01L21/02024 , H01L21/304 , H01L21/30625 , H01L21/3221 , H01L25/065 , H01L2224/48091 , H01L2924/181 , H01L2924/00014 , H01L2924/00012
摘要： A semiconductor wafer, die and semiconductor package formed therefrom are disclosed, where the inactive surface of the wafer has an extrinsic gettering pattern formed from a texturing process. In examples, the texturing process follows a polishing process that removes stress concentration point from the inactive surface of the wafer.
摘要翻译： 公开了从其形成的半导体晶片，管芯和半导体封装，其中晶片的非活性表面具有由纹理化工艺形成的外在吸气图案。 在实例中，纹理化处理遵循从晶片的非活性表面去除应力集中点的抛光工艺。
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