-
1.发明授权Process for making a cosmetically or pharmaceutically-acceptable emulsion or gel composition 失效制备美容或药学上可接受的乳液或凝胶组合物的方法公开(公告)号：US06300442B1
公开(公告)日：2001-10-09
申请号：US09396000
申请日：1999-03-13
IPC分类号： C08F232
CPC分类号： A61K8/06 , A61K8/062 , A61K8/064 , A61K8/8141 , A61K9/0014 , A61K2800/57 , A61Q17/04 , A61Q19/00 , C08F2/06 , C08F226/10 , C08F226/04 , C08F216/125
摘要： A process of making a cosmetically or pharmaceutically-acceptable emulsion or gel composition which comprises: (a) heating a reaction mixture comprising, by weight, about 5-70% of a vinyl monomer in about 30-95% of an oil as solvent, wherein said oil is selected from the group consisting of a silicone oil, a mineral oil and a water-insoluble organic ester and a free radical initiator, optionally in the presence of a crosslinking agent and/or an oil soluble surfactant, with agitation, under an inert gas, at about 40-150° C., wherein the oil is present in an amount sufficient to keep the resultant vinyl polymer in a stirrable state until the end of the polymerization, (b) adding a surfactant, if a suitable surfactant was not present during polymerization, and, (c) then adding water to form an oil-in-water, a water-in-oil or a water-in-oil-in-water emulsion or gel, in a volume ratio of oil-in-water of 30:70 to 10:90, or water-in-oil of 90:10 to 30:70.
摘要翻译： 制备化妆品或药学上可接受的乳液或凝胶组合物的方法，其包括：（a）加热反应混合物，该反应混合物包含以约30-95％油为溶剂的约5-70％的乙烯基单体， 其中所述油选自硅油，矿物油和水不溶性有机酯和自由基引发剂，任选地在交联剂和/或油溶性表面活性剂的存在下搅拌，在 惰性气体，在约40-150℃下，其中油以足以保持所得乙烯基聚合物处于可搅拌状态直至聚合结束的量存在，（b）如果合适的表面活性剂 在聚合期间不存在，然后（c）然后加入水以形成水包油，油包水或水包油包水乳液或凝胶，其体积比为油 - 水分为30:70至10:90，或油包水为90:10至30:70。
-
2.发明授权Vinyl amide polymer delivery system for hair and skin treating compositions 有权用于头发和皮肤处理组合物的乙烯基酰胺聚合物递送系统公开(公告)号：US06177068B1
公开(公告)日：2001-01-23
申请号：US09203910
申请日：1998-12-02
IPC分类号： A61K706
CPC分类号： A61K8/06 , A61K8/062 , A61K8/064 , A61K8/8141 , A61K9/0014 , A61K2800/57 , A61Q17/04 , A61Q19/00 , C08F2/06 , C08F226/10 , C08F226/04 , C08F216/125
摘要： A cosmetically active oil-in-water (o/w) or water-in-oil (w/o) emulsion, for topical applications comprising (a) the reaction product of a non-aqueous, heterogeneous polymerization of a liquid reaction mixture containing between about 5 and about 70%, preferably 10-40%, by weight, of N-vinylamide monomer in an oil solvent, a free radical initiator, between about 0.1 and about 2.5% by weight of a crosslinking agent and optionally a surfactant, (b) water sufficient to form said emulsion, (c) a cosmetically active hair and/or skin treating chemical or chemical composition and optionally (d) a surfactant.
摘要翻译： 用于局部应用的美容活性的水包油（o / w）或油包水（w / o）乳液，其包含（a）液态反应混合物的非水非均相聚合反应产物，其含有 在油溶剂，自由基引发剂中的约5-约70重量％，优选10-40重量％的N-乙烯基酰胺单体，约0.1-约2.5重量％的交联剂和任选的表面活性剂， （b）足以形成所述乳液的水，（c）处理化学或化学成分的美容活性毛发和/或皮肤，以及任选地（d）表面活性剂。
-
公开(公告)号：US6048522A
公开(公告)日：2000-04-11
申请号：US121380
申请日：1998-07-23
IPC分类号： A61K8/06 , A61K8/81 , A61K9/00 , A61K9/113 , A61K31/74 , A61K47/14 , A61K47/32 , A61K47/44 , A61Q17/04 , A61Q19/00 , C08F2/06 , C08F2/12 , C08F2/14 , C08F2/24 , C08F2/32 , C08F26/10 , C08F226/10 , C08G77/04 , A61K31/695 , A61K31/79
CPC分类号： A61K8/062 , A61K47/14 , A61K47/32 , A61K47/44 , A61K8/06 , A61K8/064 , A61K8/8141 , A61K9/0014 , A61Q17/04 , A61Q19/00 , C08F2/06 , C08F226/10 , A61K2800/57 , Y10T428/2987
摘要： A controlled-release, drug-delivery, emulsion composition for topical application comprising (a) the reaction product of the non-aqueous, heterogeneous polymerization of a reaction mixture of about 5-70%, preferably 10-30%, by weight, of a vinyl monomer in an oil as solvent, and a free radical initiator, optionally in the presence of a crosslinking agent and/or a surfactant, wherein the oil solvent is present in an amount sufficient to keep the resultant polymer in a stirrable state throughout the polymerization, (b) water, (c) a surfactant and (d) a pharmaceutical medicament.
摘要翻译： 一种用于局部施用的控释药物递送乳剂组合物，其包含（a）反应混合物的非水非均相聚合反应产物，其反应混合物的重量比为约5-70％，优选为10-30％ 任选在交联剂和/或表面活性剂存在下，油中的乙烯基单体和溶剂中的自由基引发剂，其中油溶剂的存在量足以使得到的聚合物在整个过程中保持在可搅拌状态 聚合，（b）水，（c）表面活性剂和（d）药物。
-
4.发明授权Non-aqueous, heterogeneous polymerization process and reaction product obtained thereby 失效由此获得非水，非均相聚合方法和反应产物公开(公告)号：US06255421B1
公开(公告)日：2001-07-03
申请号：US08988121
申请日：1997-12-10
IPC分类号： C08F212
CPC分类号： C08F226/10 , A61K8/06 , A61K8/062 , A61K8/064 , A61K8/8141 , A61K9/0014 , A61K2800/57 , A61Q17/04 , A61Q19/00 , C08F2/06 , C08F226/04 , C08F216/125
摘要： A non-aqueous, heterogeneous polymerization process comprises heating a reaction mixture of about 5-70%, preferably 10-30%, by weight, of a vinyl monomer in an oil as solvent, and a free radical initiator, optionally in the presence of a crosslinking agent and/or a surfactant, wherein the oil solvent is present in an amount sufficient to keep the resultant polymer in a stirrable state throughout the polymerization. The polymer reaction product is capable of forming a uniform emulsion or gel upon addition of water thereto.
摘要翻译： 非水非均相聚合方法包括加热约5-70％，优选10-30％（重量）的作为溶剂的油中的乙烯基单体和一种自由基引发剂的反应混合物，任选地在 交联剂和/或表面活性剂，其中油溶剂的存在量足以使得所得聚合物在整个聚合过程中处于可搅拌状态。 聚合物反应产物能够在加入水后形成均匀的乳液或凝胶。
-
5.发明授权
公开(公告)号：US5225524A
公开(公告)日：1993-07-06
申请号：US907982
申请日：1992-07-02
摘要： A process is described for rendering amino-group polymer solutions substantially odorless. In one embodiment, a solution of the terpolymer of vinyl pyrrolidone, vinyl caprolactam and dimethylaminoethyl methacrylate is treated with 0.1-10% by weight of an acidic compound or an acidic ion-exchange resin to render the solution substantially odorless. Other vinyl pyrrolidone polymer solutions in water and alcohol are treated similarly with equally effective results.
摘要翻译： 描述了使氨基聚合物溶液基本上无臭的方法。 在一个实施方案中，将乙烯基吡咯烷酮，乙烯基己内酰胺和甲基丙烯酸二甲基氨基乙酯的三元共聚物溶液用0.1-10重量％的酸性化合物或酸性离子交换树脂处理，使溶液基本无臭。 水和醇中的其它乙烯基吡咯烷酮聚合物溶液的处理方式同样有效。
-
6.发明授权Reactive extrusion process for making mixed salts of polymers containing an anhydride, acid or ester side groups 失效用于制备含有酸酐，酸或酯侧基的聚合物的混合盐的反应性挤出方法
公开(公告)号：US5635568A
公开(公告)日：1997-06-03
申请号：US516029
申请日：1995-08-17
CPC分类号： C08F8/44 , B29C67/246
摘要： A process of making a mixed salt of a polymer containing an anhydride, acid or ester side groups therein which comprises:(a) forming a reaction mixture of the polymer, mixed salt compounds and water, in a predetermined proportion, as a paste or slurry,(b) reacting and extruding the paste or slurry at a predetermined temperature to form the mixed salt of the polymer, and(c) drying the resultant reaction product.
摘要翻译： 制备含有酸酐，酸或酯侧基的聚合物的混合盐的方法，其包括：（a）以预定比例形成聚合物，混合盐化合物和水的反应混合物，作为糊剂或浆料 ，（b）在预定温度下使糊料或浆料反应和挤出以形成聚合物的混合盐，和（c）干燥所得的反应产物。
-
7.发明授权Stabilized aqueous solution of a C.sub.1 -C.sub.5 alkyl vinyl ether and maleic acid copolymer 失效稳定的C1-C5烷基乙烯基醚和马来酸共聚物的水溶液
公开(公告)号：US5214089A
公开(公告)日：1993-05-25
申请号：US761535
申请日：1991-09-18
摘要： What is provided herein is a stabilized aqueous solution of a C.sub.1 -C.sub.5 alkyl vinyl ether and maleic acid copolymer which includes about 10-500 ppm of an inorganic reducing agent as a stabilizing additive, said reducing agent being effective to prevent oxygen from the air and peroxides contained in polymer system from degrading the copolymer. Preferably the reducing agent is sulfur dioxide and salts derived from sulfur dioxide and alkali metals such as, sodium or potassium bisulfite, sodium or potassium metabisulfite, sodium or potassium thiosulfite, or sodium or potassium sulfite.
摘要翻译： 本文提供的是稳定的C1-C5烷基乙烯基醚和马来酸共聚物的水溶液，其包括约10-500ppm的无机还原剂作为稳定添加剂，所述还原剂有效地防止来自空气的氧和 包含在聚合物体系中的过氧化物降解共聚物。 优选地，还原剂是二氧化硫和二氧化硫和碱金属的盐，例如亚硫酸氢钠或亚硫酸氢钾，焦亚硫酸钠或焦碳酸钾，硫代硫酸钠或钾，亚硫酸钠或亚硫酸钾。
-
8.发明授权Colorless, non-toxic, stabilized aqueous solution of a C1-C5 alkyl vinyl ether and maleic acid copolymers 失效无色，无毒，稳定的C1-C5烷基乙烯基醚和马来酸共聚物的水溶液
公开(公告)号：US5449715A
公开(公告)日：1995-09-12
申请号：US91809
申请日：1993-07-15
摘要： What is provided herein is a colorless, stabilized aqueous solution of a C.sub.1 -C.sub.5 alkyl vinyl ether and maleic acid copolymer which includes about 100 to 1,000 ppm of an additive mixture of (a) about 30-70% by weight of ethylenediaminetetraacetic acid (EDTA) or its salts, such as the disodium, trisodium, tetrasodium or disodium-calcium salts, and (b) about 30-70% by weight of a secondary additive which is an organic antioxidant and/or free radical scavenger selected from t-butylhydroquinone, propyl gallate, butylated hydroxy-anisole (BHA), butylated hydroxy-toluene (BHT), 4-hydroxymethyl-2,6-di-tert-butylphenol, 2,4,5-trihydroxy-butyrophenone (THBP) and N,N-diethylhydroxylamine, said stabilized solution exhibiting a retention of at least about 85-90% of its original viscosity after 3 months. Preferably, the solution is prepared by hydrolyzing the corresponding anhydride in the presence of said additive mixture.
摘要翻译： 本文提供的是C1-C5烷基乙烯基醚和马来酸共聚物的无色稳定的水溶液，其包含约100至1,000ppm的（a）约30-70重量％的乙二胺四乙酸（EDTA）的添加剂混合物 ）或其盐，例如二钠，三钠，四钠或二钠钙盐，和（b）约30-70重量％的第二添加剂，其是选自叔丁基氢醌的有机抗氧化剂和/或自由基清除剂 ，没食子酸丙酯，丁基化羟基苯甲醚（BHA），丁基化羟基甲苯（BHT），4-羟甲基-2,6-二叔丁基苯酚，2,4,5-三羟基 - 丁酰苯（THBP）和N，N - 二乙基羟胺，所述稳定化溶液在3个月后保持其原始粘度的至少约85-90％。 优选地，通过在所述添加剂混合物的存在下水解相应的酸酐来制备溶液。
-
公开(公告)号：US5216070A
公开(公告)日：1993-06-01
申请号：US760273
申请日：1991-09-16
IPC分类号： C08F2/32
CPC分类号： C08F2/32
摘要： A method for forming a water-in-oil emulsion of a water-soluble polymer by emulsion polymerization of the corresponding monomer in the presence of an initiator and an emulsifier which is a polysiloxane polyalkylene polyether copolymer. The polymerization of acidic monomer can be carried out without complete neutralization of the monomer beforehand and without adverse effects on the emulsion stability. The water-in-oil product emulsion is easily inverted to a stable oil-in-water emulsion.
摘要翻译： 在引发剂和作为聚硅氧烷聚亚烷基聚醚共聚物的乳化剂存在下，通过相应单体的乳液聚合形成水溶性聚合物的油包水乳液的方法。 酸性单体的聚合可以在不完全中和该单体的情况下进行，而对乳液的稳定性没有不利影响。 油包水乳液容易倒置成稳定的水包油乳液。
-
公开(公告)号：US5362830A
公开(公告)日：1994-11-08
申请号：US122834
申请日：1993-09-15
申请人： Jui-Chang Chuang , Jenn S. Shih , Robert B. Login
发明人： Jui-Chang Chuang , Jenn S. Shih , Robert B. Login
IPC分类号： C08F8/00 , C08F226/10 , C08F224/00 , C08K5/05 , C08L39/06
CPC分类号： C08F226/10 , C08F8/00 , C08F2800/20 , C08F2810/20
摘要： Crosslinkable copolymers of (a) 80-99% by wt. vinylpyrrolidone (VP) and 1-20% by wt. of a tertiary-amine-containing polymerizable monomer, e.g. vinylimidazole (VI) or 4-vinylpyridine (VPy), and (b) 80-99% by wt. VP and 1-20% by wt. of an epoxide-containing polymerizable monomer, e.g. allyl glycidyl ether (AGE) or glycidyl acrylate (GA), are reacted in solution, e.g. water, alcohol, or mixtures thereof, at a predetermined temperature, e.g. 50.degree.-70.degree. C., in a wt. ratio (solids basis) of (a):(b) of about 2:1 to 1:2, preferably about 1:1, in a solution concentration of about 10-30% of each, to provide a crosslinked PVP product, in gel form, suitable for use as an electrolead on a conductive foilbacking, or for bandages and wound dressings, and as a controlled release media for pharmaceuticals.
摘要翻译： （a）80-99重量％的可交联共聚物 乙烯基吡咯烷酮（VP）和1-20重量％ 的含叔胺的可聚合单体，例如。 乙烯基咪唑（VI）或4-乙烯基吡啶（VPy），和（b）80-99重量％ VP和1-20重量％ 的含环氧化物的可聚合单体，例如 烯丙基缩水甘油醚（AGE）或丙烯酸缩水甘油酯（GA）在溶液中反应。 水，醇或其混合物，例如在预定温度下。 50℃-70℃， （a）：（b）的比例（固体基准）为约2:1至1:2，优选约1:1，溶液浓度为约10-30％，以提供交联的PVP产物， 凝胶形式，适合用作导电箔片上的电泳，或用于绷带和伤口敷料，以及用作药物的控释介质。
-
-
-
-
-
-
-
-
-
搜索结果
47 条记录 (耗时 0.02 秒)
