-
公开(公告)号：US10794879B2
公开(公告)日：2020-10-06
申请号：US16534202
申请日：2019-08-07
申请人： LECO Corporation
摘要： For improving sensitivity, dynamic range, and specificity of GC-MS analysis there are disclosed embodiments of novel apparatuses based on improved characteristics of semi-open source with electron impact ionization, providing much higher brightness compared to known open EI sources. In an implementation, the source becomes compatible with multi-reflecting TOF analyzers for higher resolution analysis for improving detection limit. With improved schemes of spatial and temporal refocusing there are proposed various tandem TOF-TOF spectrometers with PSD, CID, and SID fragmentation and using either singly reflecting TOF or MR-TOF analyzers.
-
公开(公告)号：US10770280B2
公开(公告)日：2020-09-08
申请号：US15301249
申请日：2015-03-31
申请人： LECO Corporation
摘要： There is proposed a right angle time-of-flight detector comprising a conductive converter for emitting and accelerating secondary electrons, a magnetic field formed by at least one magnet for deflecting the secondary electrons at a right angle and a sealed photo-multiplier. The detector is expected to provide an extended resource and dynamic range and may be fit into tight assemblies, such as MR-TOF MS.
-
公开(公告)号：US10741377B2
公开(公告)日：2020-08-11
申请号：US16787268
申请日：2020-02-11
申请人： LECO Corporation
摘要： An ion guide includes electrodes and an RF generator. The electrodes extend in a Z-axis that is straight or curved with a radius that is larger than a distance between the electrodes. The electrodes are made of carbon filled ceramic resistors, silicon carbide, or boron carbide to form bulk resistance with specific resistance between 1 and 1000 Ohm*cm. Conductive Z-edges are disposed on each electrode. An insulating coating is disposed on one side of each electrode and oriented away from an inner region of the ion guide surrounded by said electrodes. At least one conductive track per electrode is attached on a top side of the insulating coating. The conductive track is connected to one conductive electrode edge. The RF generator has at least two sets of secondary coils with DC supplies connected to central taps of the sets of secondary coils to provide at least four distinct signals.
-
公开(公告)号：US20200185211A1
公开(公告)日：2020-06-11
申请号：US16787268
申请日：2020-02-11
申请人： LECO Corporation
摘要： An ion guide includes electrodes and an RF generator. The electrodes extend in a Z-axis that is straight or curved with a radius that is larger than a distance between the electrodes. The electrodes are made of carbon filled ceramic resistors, silicon carbide, or boron carbide to form bulk resistance with specific resistance between 1 and 1000 Ohm*cm. Conductive Z-edges are disposed on each electrode. An insulating coating is disposed on one side of each electrode and oriented away from an inner region of the ion guide surrounded by said electrodes. At least one conductive track per electrode is attached on a top side of the insulating coating. The conductive track is connected to one conductive electrode edge. The RF generator has at least two sets of secondary coils with DC supplies connected to central taps of the sets of secondary coils to provide at least four distinct signals.
-
公开(公告)号：US20190157056A1
公开(公告)日：2019-05-23
申请号：US16259769
申请日：2019-01-28
申请人： LECO Corporation
CPC分类号： H01J49/0031 , G01N2030/8482 , H01J49/0036 , H01J49/0418 , H01J49/102 , H01J49/145
摘要： One aspect of the disclosure provides a method of mass spectrometric analysis that includes producing either glow discharge within a noble gas between 3-100 mBar pressure, sampling and conditioning glow discharge products within a gas flow through a conductive channel, removing charged particles while transferring excited Ridberg atoms, and mixing conditioned discharge products with analyte flow within an enclosed chamber at elevated temperatures above 150° Celsius for producing a Penning reaction between analyte molecules and Ridberg atoms. The method further includes sampling, by a gas flow, said analyte ions for mass spectrometric analysis, and at least one of the following steps: (i) removing charge within said conditioning channel; (ii) coaxially mixing of analyte flow with the flow of conditioned plasma; and (iii) cooling of the mixed flow within a sonic or supersonic jet for reducing the region of Penning ionization to cold jet.
-
公开(公告)号：US10192723B2
公开(公告)日：2019-01-29
申请号：US15508800
申请日：2015-09-04
申请人： LECO Corporation
摘要： One aspect of the disclosure provides a method of mass spectrometric analysis that includes producing either glow discharge within a noble gas between 3-100 mBar pressure, sampling and conditioning glow discharge products within a gas flow through a conductive channel, removing charged particles while transferring excited Ridberg atoms, and mixing conditioned discharge products with analyte flow within an enclosed chamber at elevated temperatures above 150° Celsius for producing a Penning reaction between analyte molecules and Ridberg atoms. The method further includes sampling, by a gas flow, said analyte ions for mass spectrometric analysis, and at least one of the following steps: (i) removing charge within said conditioning channel; (ii) coaxially mixing of analyte flow with the flow of conditioned plasma; and (iii) cooling of the mixed flow within a sonic or supersonic jet for reducing the region of Penning ionization to cold jet.
-
公开(公告)号：US10049867B2
公开(公告)日：2018-08-14
申请号：US15695969
申请日：2017-09-05
申请人： LECO Corporation
摘要： An apparatus 41 and operation method are provided for an electrostatic trap mass spectrometer with measuring frequency of multiple isochronous ionic oscillations. For improving throughput and space charge capacity, the trap is substantially extended in one Z-direction forming a reproduced two-dimensional field. Multiple geometries are provided for trap Z-extension. The throughput of the analysis is improved by multiplexing electrostatic traps. The frequency analysis is accelerated by the shortening of ion packets and either by Wavelet-fit analysis of the image current signal or by using a time-of-flight detector for sampling a small portion of ions per oscillation. Multiple pulsed converters are suggested for optimal ion injection into electrostatic traps.
-
公开(公告)号：US09941107B2
公开(公告)日：2018-04-10
申请号：US14441700
申请日：2013-11-08
申请人： LECO Corporation
CPC分类号： H01J49/406 , H01J49/0031 , H01J49/405 , H01J2237/121
摘要： A method and apparatus are disclosed for improving resolution and duty-cycle of a multi-reflecting TOF mass spectrometer (MR-TOF) by arranging a cylindrical analyzer having an appropriate radial deflection means, means for limiting ion divergence in the tangential direction and a pulsed source providing ion packet divergence of less than 1 mm*deg. There are disclosed embodiments for fifth-order focusing cylindrical ion minors. Separate embodiments provide parallel tandem MS-MS within a single cylindrical MR-TOF.
-
公开(公告)号：US20170365457A1
公开(公告)日：2017-12-21
申请号：US15696770
申请日：2017-09-06
申请人： LECO Corporation
CPC分类号： H01J49/282 , H01J49/0031 , H01J49/0036 , H01J49/062 , H01J49/40 , H01J49/401 , H01J49/406 , H01J49/4245
摘要： An apparatus 41 and operation method are provided for an electrostatic trap mass spectrometer with measuring frequency of multiple isochronous ionic oscillations. For improving throughput and space charge capacity, the trap is substantially extended in one Z-direction forming a reproduced two-dimensional field. Multiple geometries are provided for trap Z-extension. The throughput of the analysis is improved by multiplexing electrostatic traps. The frequency analysis is accelerated by the shortening of ion packets and either by Wavelet-fit analysis of the image current signal or by using a time-of-flight detector for sampling a small portion of ions per oscillation. Multiple pulsed converters are suggested for optimal ion injection into electrostatic traps.
-
公开(公告)号：US09786482B2
公开(公告)日：2017-10-10
申请号：US14798260
申请日：2015-07-13
申请人： LECO Corporation
CPC分类号： H01J49/282 , H01J49/0031 , H01J49/0036 , H01J49/062 , H01J49/40 , H01J49/401 , H01J49/406 , H01J49/4245
摘要： A mass spectrometer including an ion source, an ion guide, a pulsed converter, and an electrostatic analyzer is disclosed, along with a method of mass spectrometry and an ion injector. The ion source generates ions, such as ions within a continuous or a quasi-continuous ion beam. The ion guide receives a portion of the ions generated by the ion source. The pulsed converter, which receives ions from the ion guide, includes at least one electrode connected to a RF signal. The pulsed converter may include a means for ejecting the ions in the form of ion packets. The electrostatic analyzer forms a two-dimensional electrostatic field in an X-Y plane. The electrostatic field is substantially extended in a Z-direction that is locally orthogonal to the X-Y plane and may be curved or linear. Ions undergo isochronous ion oscillations in the electrostatic field. The pulsed converter and electrostatic analyzer are Z-directionally elongated.
-
-
-
-
-
-
-
-
-
搜索结果
73 条记录 (耗时 0.026 秒)
