公开(公告)号：US12092605B2

公开(公告)日：2024-09-17

申请号：US18166745

申请日：2023-02-09

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Marc Haberstroh ,  Geoffrey Dahlhoff

IPC: G01N27/447 ,  G01F23/263 ,  G01R19/25

CPC classification number: G01N27/44713 ,  G01F23/263 ,  G01N27/44782 ,  G01R19/25

Abstract: The present disclosure relates, in some embodiments, to a system for measuring capillary electrophoresis current. The system includes a plurality of capillaries, where each capillary has a cathode end and an anode end. The system further includes a plurality of cathode buffers. Each of the cathode buffers is configured to be electrically isolated from the other cathode buffers. Further, each cathode buffer is associated with one capillary of the plurality of capillaries. The cathode end of each capillary is immersed in its associated cathode buffer. The system includes a plurality of current sensors, each current sensor associated with one capillary of the plurality of capillaries for measuring current. In some embodiments, the plurality of capillaries is four capillaries.

公开(公告)号：US11339425B2

公开(公告)日：2022-05-24

申请号：US16382294

申请日：2019-04-12

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Jacob K. Freudenthal ,  Geoffrey Dahlhoff ,  Kevin Maher ,  Ming Song Chen ,  Gary Lim ,  Ronald Danehy ,  David Fortescue ,  Ming Shen ,  Woon Liang Soh ,  Francis T. Cheng ,  Ruoyun Wu ,  Thiam Chye Lee ,  Gary A. Chappell ,  Chee Kiong Lim ,  Jeff Dere ,  Ted Straub ,  Jorge Fonseca ,  Kuan Moon Boo ,  Soo Yong Lau

IPC: C12Q1/686 ,  B01L3/00 ,  B01L7/00

Abstract: A biological analysis system is provided. The system comprises an interchangeable assembly configured to accommodate any one of a plurality of sample holders, each respective sample holder configured to receive a plurality of samples. The system also includes a control system configured to cycle the plurality of samples through a series of temperatures. The system further includes an optical system configured to detect fluorescent signals emitted from the plurality of samples. The optical system, in particular, can comprise a single field lens, an excitation source, an optical sensor, and a plurality of filter components. The excitation source can be one or more light emitting diodes. The field lends can be a bi-convex lens.

公开(公告)号：US20140213487A1

公开(公告)日：2014-07-31

申请号：US14348504

申请日：2012-09-28

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Jacob K. Freudenthal ,  Geoffrey Dahlhoff ,  Kevin Maher ,  Ming Song Chen ,  Gary Lim ,  Ronald Danehy ,  David Fortescue ,  Ming Shen ,  Woon Liang Soh ,  Francis T. Cheng ,  Ruoyun Wu ,  Thiam Chye Lee ,  Gary A. Chappell ,  Chee Kiong Lim ,  Jeff Dere ,  Theodore E. Straub ,  Jorge Fonseca ,  Kuan Moon Boo ,  Soo Yong Lau

IPC: B01L7/00 ,  C12Q1/68

CPC classification number: C12Q1/686 ,  B01L3/50855 ,  B01L3/50857 ,  B01L7/52 ,  B01L2200/023 ,  B01L2200/025 ,  B01L2200/028 ,  B01L2200/143 ,  B01L2300/021 ,  B01L2300/046 ,  B01L2300/0654 ,  B01L2300/0829 ,  B01L2300/1827 ,  B01L2300/1844

Abstract: A biological analysis system is provided. The system comprises an interchangeable assembly configured to accommodate any one of a plurality of sample holders, each respective sample holder configured to receive a plurality of samples. The system also includes a control system configured to cycle the plurality of samples through a series of temperatures. The system further includes an optical system configured to detect fluorescent signals emitted from the plurality of samples. The optical system, in particular, can comprise a single field lens, an excitation source, an optical sensor, and a plurality of filter components. The excitation source can be one or more light emitting diodes. The field lens can be a bi-convex lens.

Abstract translation: 提供生物分析系统。 该系统包括被配置为容纳多个样品保持器中的任何一个的可互换组件，每个样品保持器被配置为接收多个样品。 该系统还包括被配置为使多个样品循环通过一系列温度的控制系统。 该系统还包括被配置为检测从多个样本发射的荧光信号的光学系统。 特别地，光学系统可以包括单个场透镜，激发源，光学传感器和多个滤光器组件。 激发源可以是一个或多个发光二极管。 场透镜可以是双凸透镜。