公开(公告)号：US20220088561A1

公开(公告)日：2022-03-24

申请号：US17505075

申请日：2021-10-19

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Colin BRENAN ,  Jamie CHO ,  Javier GARCIA ,  Robert HESS ,  Tanya KANIGAN ,  Arrin KATZ ,  Namyong KIM ,  John LINTON ,  Shailesh SRIVASTAVA ,  Karl YODER

IPC: B01J19/00 ,  B01L3/00

Abstract: A method of registering a location of a dispenser array in relation to a microfluidic array is provided. One of the dispenser array and the microfluidic array can be movable in relation to the frame, and the other can be fixed relative to the frame. Their relative positions can be identified by a set of coordinates. Identification of a fiducial marker can occur in a manner permitting the fiducial reference to appear in a first position of a field of view of a first camera when the dispenser array or the microfluidic array is in an alignment position. Quantities related to a vector displacement from the alignment position to a fixed position on the microfluidic array or the dispenser array can be identified. Quantities determined can be used to guide positioning of the dispenser array relative to the microfluidic array.

公开(公告)号：US20190118173A1

公开(公告)日：2019-04-25

申请号：US16119327

申请日：2018-08-31

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Tanya S. KANIGAN ,  Steve SMITH ,  John LINTON ,  Robert HESS ,  Karl YODER ,  Colin J. H. BRENAN

IPC: B01L3/00 ,  B01L3/02

Abstract: An interface is provided for storing microfluidic samples in a nanoliter sample chip. A fluid access structure provides a fluid access region to a selected subset of sample wells from an array of sample wells. A fluid introduction mechanism introduces a sample fluid to the fluid access region so that the sample wells in the selected subset are populated with the sample fluid without the unselected sample wells being populated with the sample fluid.

公开(公告)号：US20160167044A1

公开(公告)日：2016-06-16

申请号：US15049710

申请日：2016-02-22

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Tanya S. KANIGAN ,  Steve SMITH ,  John LINTON ,  Robert HESS ,  Karl YODER ,  Colin John Herbert BRENAN

IPC: B01L3/00

CPC classification number: B01L3/5085 ,  B01L3/0241 ,  B01L3/0244 ,  B01L3/5025 ,  B01L3/50857 ,  B01L3/563 ,  B01L2200/021 ,  B01L2200/027 ,  B01L2200/0605 ,  B01L2200/0636 ,  B01L2200/0642 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/0829 ,  B01L2300/0864 ,  B01L2300/12 ,  B01L2300/161 ,  B33Y70/00 ,  B33Y80/00 ,  Y10T137/0318 ,  Y10T137/1624 ,  Y10T137/206 ,  Y10T436/2525

Abstract: An interface is provided for storing microfluidic samples in a nanoliter sample chip. A fluid access structure provides a fluid access region to a selected subset of sample wells from an array of sample wells. A fluid introduction mechanism introduces a sample fluid to the fluid access region so that the sample wells in the selected subset are populated with the sample fluid without the unselected sample wells being populated with the sample fluid.

Abstract translation: 提供了用于将微流体样品存储在纳升级样品芯片中的界面。 流体通道结构从样品阱阵列向选定的样品阱子集提供流体通路区域。 流体引入机构将样品流体引入流体存取区域，使得所选择的子集中的样品孔填充有样品流体，而未选择的样品池填充有样品流体。