公开(公告)号：US20220119701A1

公开(公告)日：2022-04-21

申请号：US17514492

申请日：2021-10-29

Applicant: Life Technologies Corporation

Inventor： Adam YORK ,  Eric WELCH ,  Kyle GEE ,  Xin WANG ,  Robert AGGELER ,  Yi-Zhen HU

IPC: C09K11/02 ,  C09B67/00 ,  C09K11/06 ,  G01N33/50 ,  G01N33/533 ,  G01N33/58 ,  H04L12/18

Abstract: Water-soluble, fluorescent particles and compositions, kits, and methods of making and using such particles are disclosed. Processes for preparing fluorescent particles and for controlling the size, polydispersity and optical properties of such particles also are provided.

公开(公告)号：US20190194532A1

公开(公告)日：2019-06-27

申请号：US16324730

申请日：2017-08-24

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Adam YORK ,  Eric WELCH ,  Kyle GEE ,  Xin WANG ,  Robert AGGELER ,  Yi-Zhen HU

IPC: C09K11/02 ,  C09K11/06 ,  C09B67/00 ,  G01N33/50 ,  G01N33/533 ,  G01N33/58

CPC classification number: C09K11/025 ,  C09B68/41 ,  C09K11/06 ,  C09K2211/1416 ,  C09K2211/1483 ,  G01N33/5005 ,  G01N33/533 ,  G01N33/582 ,  H04L12/1822 ,  H04L12/1827 ,  H04L12/1895 ,  H04L67/10

Abstract: Water-soluble, fluorescent particles and compositions, kits, and methods of making and using such particles are disclosed. Processes for preparing fluorescent particles and for controlling the size, polydispersity and optical properties of such particles also are provided.

公开(公告)号：US20170247504A1

公开(公告)日：2017-08-31

申请号：US15491650

申请日：2015-08-14

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Kyle GEE ,  Xin WANG ,  Hee Chol KANG ,  Aimei CHEN ,  Yexin WU ,  Yi-Zhen HU ,  Robert AGGELER ,  Quentin LOW

IPC: C08G61/12 ,  G01N33/545 ,  G01N33/58 ,  G01N33/533 ,  C07F7/08 ,  C09K11/06

CPC classification number: C08G61/123 ,  C07F7/0816 ,  C07F7/083 ,  C08G2261/122 ,  C08G2261/124 ,  C08G2261/1424 ,  C08G2261/145 ,  C08G2261/1644 ,  C08G2261/1646 ,  C08G2261/3142 ,  C08G2261/3244 ,  C08G2261/334 ,  C08G2261/344 ,  C08G2261/411 ,  C08G2261/522 ,  C08G2261/5222 ,  C08G2261/72 ,  C08G2261/94 ,  C08L65/00 ,  C09K11/06 ,  C09K2211/1416 ,  C09K2211/1491 ,  G01N33/533 ,  G01N33/545 ,  G01N33/582 ,  H01L51/0039 ,  H01L51/0043 ,  H01L51/0094

Abstract: Water-soluble, conjugated polymers containing one or more dibenzosilole monomer residues, as well as compositions, kits, and methods of making and using such polymers are disclosed. Also disclosed are dibenzosilole derivatives substituted with one or more water-solubilizing groups, and methods of making and using such derivatives to prepare water-soluble dibenzosilole polymers.

公开(公告)号：US20210324198A1

公开(公告)日：2021-10-21

申请号：US17150247

申请日：2019-08-08

Applicant: Life Technologies Corporation

Inventor： Jongtae YANG ,  Xin WANG ,  Yi-Zhen HU ,  Kyle GEE ,  Aimei CHEN ,  Scott BENSON ,  Brian EVANS ,  Aleksey RUKAVISHNIKOV

IPC: C09B11/28 ,  C07F7/08 ,  C07F9/6561 ,  C12Q1/6816 ,  C12Q1/6869 ,  G01N33/58

Abstract: Silicon-substituted rhodamine compounds are disclosed herein. Also described herein are SiR dyes comprising at least one vinyl group attached to the Si atom (10 position) of the SiR dye. Derivatives, functionalized versions, conjugates, kits, related synthetic methods and uses of SiR compounds also are provided. Silicon-rhodamine (SiR) dyes can provide bright fluorescence at far red wavelengths and exhibit good photostability. The compounds described herein can be useful for fluorescent labeling and detection of biological samples.