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    Testing method and configurations for multi-ejector system
    5.
    发明授权
    Testing method and configurations for multi-ejector system 失效
    多喷射器系统的测试方法和配置

    公开(公告)号：US06740530B1

    公开(公告)日：2004-05-25

    申请号：US09718733

    申请日：2000-11-22

    申请人： Richard H. Bruce ,  Scott A. Elrod ,  Jaan Noolandi ,  David A. Horine ,  Babur B. Hadimioglu

    发明人： Richard H. Bruce ,  Scott A. Elrod ,  Jaan Noolandi ,  David A. Horine ,  Babur B. Hadimioglu

    IPC分类号： G01N110

    CPC分类号： B01L3/0268 ,  B01J19/0046 ,  B01J2219/00378 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00603 ,  B01J2219/00659 ,  B01J2219/00693 ,  B41J2/14008 ,  B41J2002/14322 ,  C40B60/14 ,  Y10T436/25 ,  Y10T436/2575

    摘要： Methods for testing proper operation of drop ejection units in a multi-ejector system are provided to determine whether the drop ejectors have been properly filled and/or the ejectors are emitting fully formed droplets. The methods include testing the ejectors prior to drop ejection. In this method, a priming system is used wherein fluid received by the priming system is ejected onto a test substrate to allow a scanner to determine the existence of the fluids at selected locations. The selected locations are correlated to the drop ejection units to determine which ejection units do not have biofluid or sufficient biofluid. A further method allows for ejection prior to printing, on a test substrate wherein testing for both the fullness of the ejector units as well as proper emission of the ejectors of droplets may be tested. The ejectors after being primed, eject the biofluids which are then scanned and correlated to each individual ejector. A further method provided is a laser scattering method wherein a laser beam is interposed between the drop emission path of the ejectors. Laser detection then determines whether a correlated drop ejector is properly emitting droplets.

    摘要翻译： 提供了用于测试多喷射器系统中液滴喷射单元的正确操作的方法，以确定液滴喷射器是否已经被适当地填充和/或喷射器正在发射完全形成的液滴。 这些方法包括在喷射之前测试喷射器。 在该方法中，使用起动系统，其中由起动系统接收的流体被喷射到测试基板上，以允许扫描仪确定在选定位置处的流体的存在。 所选择的位置与液滴喷射单元相关，以确定哪些喷射单元不具有生物流体或足够的生物流体。 另外的方法允许在打印之前在测试基板上进行喷射，其中可以测试喷射器单元的充满度以及液滴喷射器的适当发射。 喷射器被喷涂后，喷射生物流体，然后将其扫描并与每个喷射器相关联。 提供的另一种方法是激光散射方法，其中激光束插入在喷射器的液滴发射路径之间。 然后，激光检测确定相关的液滴喷射器是否正确地发射液滴。

    Devices for biofluid drop ejection
    6.
    发明授权
    Devices for biofluid drop ejection 有权
    生物流体液滴喷射装置

    公开(公告)号：US06713022B1

    公开(公告)日：2004-03-30

    申请号：US09724987

    申请日：2000-11-22

    申请人： Jaan Noolandi ,  David A. Horine ,  Babur B. Hadimioglu ,  Richard H. Bruce ,  Joy Roy ,  Scott A. Elrod

    发明人： Jaan Noolandi ,  David A. Horine ,  Babur B. Hadimioglu ,  Richard H. Bruce ,  Joy Roy ,  Scott A. Elrod

    IPC分类号： B41J2175

    CPC分类号： B01L3/0268 ,  B01L2400/0439 ,  G01N35/1002 ,  G01N2035/102 ,  G01N2035/1041

    摘要： A biofluid drop ejection unit for ejecting biofluid drops. A biofluid drop ejection mechanism of such a unit includes a transducer, which generates energy used to emit the biofluid drop. Further provided is a reagent cartridge or biofluid containment area which holds the biofluid. The reagent cartridge or biofluid containment area is configured to hold low volumes of biofluid and to avoid contamination of the biofluid. The reagent cartridge or biofluid containment area is in operational connection with the drop ejection mechanism such that upon operation of the drop ejection mechanism, biofluid drops are emitted. The biofluid drop ejection mechanism is a high efficiency device, and may be configured as two separate pieces or as a single disposable unit.

    摘要翻译： 用于喷射生物流体滴的生物流体滴落喷射单元。 这种单元的生物流体液滴喷射机构包括换能器，其产生用于发射生物流体滴的能量。 另外还提​​供了一个保持生物流体的试剂盒或生物流体容纳区域。 试剂盒或生物流体容纳区域被配置为保持低体积的生物流体并避免污染生物流体。 试剂盒或生物流体容纳区域与液滴喷射机构操作连接，使得在液滴喷射机构的操作时，发射生物流体液滴。 生物流体液滴喷射机构是高效率的装置，并且可以被配置为两个分开的部件或者作为单个一次性部件。

    Surface ripple wave diffusion in apertured free ink surface level controllers for acoustic ink printers
    7.
    发明授权
    Surface ripple wave diffusion in apertured free ink surface level controllers for acoustic ink printers 失效
    表面波纹扩散在无孔墨水表面液位控制器的声学墨水打印机

    公开(公告)号：US5216451A

    公开(公告)日：1993-06-01

    申请号：US815002

    申请日：1992-12-27

    申请人： Eric G. Rawson ,  Scott A. Elrod ,  Babur B. Hadimioglu ,  Calvin F. Quate ,  Butrus T. Khuri-Yakub

    发明人： Eric G. Rawson ,  Scott A. Elrod ,  Babur B. Hadimioglu ,  Calvin F. Quate ,  Butrus T. Khuri-Yakub

    IPC分类号： B41J2/14

    CPC分类号： B41J2/14008

    摘要： The free ink surface levels of acoustic ink printers are controlled by cap structures that have substantially non-retroreflective aperture configurations. The non-retroreflective configurations of the apertures of these cap structures cause diffusive scattering or directional deflection of the reflected surface ripple waves, thereby significantly reducing the time that is required for the oscillatory perturbations, which are caused by reflection of the surface ripple waves that are generated during the droplet ejection process, to dissipate to a negligibly low amplitude in the critical local areas of the ejection sites. This, in turn, increases the droplet ejection rates at which printers having such cap structures can be operated asynchronously.

    摘要翻译： 声学墨水打印机的自由墨水表面水平由具有基本上非回射孔径配置的盖结构控制。 这些盖结构的孔的非回射结构引起反射表面纹波的漫射散射或方向偏转，从而显着减少振荡扰动所需的时间，这是由表面波纹波的反射引起的 在液滴喷射过程中产生，以在喷射位置的关键局部区域中消散到可忽略的低振幅。 这又增加了具有这种帽结构的打印机可以异步操作的液滴喷射速率。

    Level sense and control system for biofluid drop ejection devices
    9.
    发明授权
    Level sense and control system for biofluid drop ejection devices 失效
    生物流体喷射装置的液位感应和控制系统

    公开(公告)号：US06623700B1

    公开(公告)日：2003-09-23

    申请号：US09721386

    申请日：2000-11-22

    申请人： David A. Horine ,  Babur B. Hadimioglu ,  Richard H. Bruce ,  Jaan Noolandi ,  Scott A. Elrod

    发明人： David A. Horine ,  Babur B. Hadimioglu ,  Richard H. Bruce ,  Jaan Noolandi ,  Scott A. Elrod

    IPC分类号： B01L302

    CPC分类号： B41J2/17566 ,  B41J2/1714 ,  Y10T436/2575

    摘要： A level control mechanism is provided for a biofluid drop ejection device which ejects biofluid drops in small volumes. The biofluid drop device includes a drop ejection mechanism having a transducer which generates energy used to emit the biofluid drops. A reagent cartridge or biofluid holding area holds a biofluid, isolated from the drop ejection mechanism to avoid contamination between the biofluid drop ejection mechanism and the reagent cartridge. The reagent cartridge is connected to the drop ejection mechanism such that upon operation of the mechanism, the biofluid is emitted in controlled biofluid drops. A level sensor is positioned to sense a height of the biofluid within the cartridge. Upon sensing the height of the biofluid below a certain level, an adjustment is made to the height by providing at least one of additional biofluid to the cartridge, and raising the level of the entire reagent cartridge.

    摘要翻译： 为生物流体液滴喷射装置提供液面控制机构，其以小体积喷射生物流体液滴。 生物流体液滴装置包括液滴喷射机构，其具有产生用于发射生物流体滴的能量的换能器。 试剂盒或生物流体保持区域保持与液滴喷射机构隔离的生物流体，以避免生物流体液滴喷射机构和试剂盒之间的污染。 试剂盒连接到液滴喷射机构，使得在机构操作时，生物流体在受控的生物流体滴下发射。 水平传感器被定位成感测盒内的生物流体的高度。 当感测到生物流体的高度低于一定水平时，通过向盒提供至少一种额外的生物流体，并提高整个试剂盒的水平来调节高度。

    Quality control mechanism and process for a biofluid multi-ejector system
    10.
    发明授权
    Quality control mechanism and process for a biofluid multi-ejector system 失效

    公开(公告)号：US06514704B2

    公开(公告)日：2003-02-04

    申请号：US09773804

    申请日：2001-02-01

    申请人： Richard H. Bruce ,  Scott A. Elrod ,  Babur B. Hadimioglu ,  David A. Horine ,  Jaan Noolandi ,  Joy Roy ,  Robert A. Sprague

    发明人： Richard H. Bruce ,  Scott A. Elrod ,  Babur B. Hadimioglu ,  David A. Horine ,  Jaan Noolandi ,  Joy Roy ,  Robert A. Sprague

    IPC分类号： C12Q168

    CPC分类号： G01N35/10 ,  G01N35/00712 ,  G01N35/1009 ,  G01N2035/1037 ,  G06F19/00

    摘要： A method and mechanism for ensuring quality control in printed biological assays is provided. A multi-ejector system having a plurality of individual drop ejectors is loaded with a variety of biofluids. Biofluids include at least a carrier fluid, a biological material to be used in the testing, and markers, such as fluorescent dyes. Data regarding the biofluid loaded in each of the drop ejectors is stored along with an expected signature output of the biofluid. Particularly, the signature output represents signals from individual ones of the fluorescent markers included within the biofluid. Once a biological assay consisting of the biofluid drops has been printed, a scanner capable of detecting the markers scans the biological assay and obtains signature output signals for each of the drops of the biological assay. A comparing operation is undertaken to compare the obtained signature output through the scanning operation, with the expected signature output signals for the biofluid loaded in the corresponding drop ejector. The biological material itself may also be tagged with a marker to ensure its inclusion in the biofluid. By the comparing operation, it is possible to verify the biofluids were loaded in the proper drop ejector, including the proper biological material, and that the drop ejectors are functioning properly.