Control of bioreactor processes
    4.
    发明授权

    公开(公告)号:US09617566B2

    公开(公告)日:2017-04-11

    申请号:US14329881

    申请日:2014-07-11

    IPC分类号: C12P7/06

    摘要: Processes, as well as associated systems and computer program (software) products, are disclosed for the biological conversion of CO into desired end products such as ethanol. The control methodologies used for these processes can advantageously result in a reduced time required for a batch operation or other initial operating period, prior to achieving a continuous operation, which may be demarcated either by the addition of fresh culture medium at a defined flow rate or by another process initiation target. The control methodologies may alternatively, or in combination, improve a process performance parameter, such as productivity of the desired end product or bacterial growth rate, during this batch operation or other initial operating period.

    MULTIPLE REACTOR SYSTEM FOR CONTINUOUS GAS FERMENTATION
    5.
    发明申请
    MULTIPLE REACTOR SYSTEM FOR CONTINUOUS GAS FERMENTATION 有权
    用于连续气体发酵的多反应器系统

    公开(公告)号:US20150072387A1

    公开(公告)日:2015-03-12

    申请号:US14324140

    申请日:2014-07-04

    摘要: A bioreactor system is provided for continuous fermentation of a gaseous substrate, said system comprising two or more primary bioreactors and one or more secondary bioreactors connected by a central bleed line. Further provided is a process for inoculating multiple bioreactors utilising a central bleed line, said process comprising passing fermentation broth from a first primary bioreactor to other primary bioreactors and/or secondary bioreactors via a central bleed line. Further provided is a process for maintaining stable fermentation of a gaseous substrate across multiple bioreactors, said process comprising providing fermentation broth from one or more operational primary bioreactors to one or more secondary bioreactors via a central bleed line.

    摘要翻译: 提供生物反应器系统用于气态底物的连续发酵,所述系统包含两个或更多个初级生物反应器和一个或多个通过中心渗流线连接的二次生物反应器。 还提供了使用中央渗血线接种多个生物反应器的方法,所述方法包括通过中央渗血线将来自第一主要生物反应器的发酵液从其它主要生物反应器和/或二级生物反应器传播。 进一步提供了一种用于在多个生物反应器上维持气态底物的稳定发酵的方法,所述方法包括通过中央渗血线从一种或多种操作的初级生物反应器提供发酵液至一种或多种次生物反应器。