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公开(公告)号:US09988598B2
公开(公告)日:2018-06-05
申请号:US14324140
申请日:2014-07-04
摘要: A bioreactor system is provided for continuous fermentation of a gaseous substrate, said system comprising two or more primary bioreactors and one or more secondary bioreactors connected by a central bleed line. Further provided is a process for inoculating multiple bioreactors utilizing a central bleed line, said process comprising passing fermentation broth from a first primary bioreactor to other primary bioreactors and/or secondary bioreactors via a central bleed line. Further provided is a process for maintaining stable fermentation of a gaseous substrate across multiple bioreactors, said process comprising providing fermentation broth from one or more operational primary bioreactors to one or more secondary bioreactors via a central bleed line.
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公开(公告)号:US20150353965A1
公开(公告)日:2015-12-10
申请号:US14829597
申请日:2015-08-18
发明人: Sean Dennis Simpson , Christophe Collet , Michael Cockrem , Simon David Oakley , Michael Koepke
CPC分类号: C12P7/28 , C01B3/38 , C01B2203/0233 , C01B2203/0255 , C01B2203/0261 , C01B2203/0405 , C01B2203/0415 , C01B2203/043 , C01B2203/0475 , C01B2203/06 , C01B2203/1058 , C01B2203/86 , C12M21/12 , C12M29/26 , C12M41/34 , C12M43/04 , C12P1/04 , C12P7/00 , C12P7/065 , C12P7/08 , C12P7/54 , C12P7/62 , Y02E50/17 , Y02E50/343 , Y02P30/30 , Y02W10/37
摘要: The invention relates to methods of capturing carbon by microbial fermentation of a gaseous substrate comprising CO. The methods of the invention include converting CO to one or more products including alcohols and/or acids and optionally capturing CO2 to improve overall carbon capture. In certain aspects, the invention relates to processes for producing alcohols, particularly ethanol, from industrial waste streams, particularly steel mill off-gas.
摘要翻译: 本发明涉及通过包含CO的气态底物的微生物发酵来捕获碳的方法。本发明的方法包括将CO转化为一种或多种包括醇和/或酸的产物,并任选地捕获CO 2以改善总体碳捕获。 在某些方面,本发明涉及从工业废物流,特别是炼钢厂废气中生产醇,特别是乙醇的方法。
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公开(公告)号:US08906655B2
公开(公告)日:2014-12-09
申请号:US13872646
申请日:2013-04-29
发明人: Will David Barker , Bjorn Daniel Heijstra , Wing Chuen Chan , Christophe Daniel Mihalcea , Loan Phuong Tran , Christophe Collet , Jason Carl Bromley , Bakir Al-Sinawi
摘要: The invention relates to a process for optimizing the production of ethanol by microbial fermentation, particularly microbial fermentation of substrates comprising CO. The process involves monitoring the hydrogen production by the microorganism, determining an optimum hydrogen production and adjusting the substrate supply rate in response to a change in the hydrogen production thereby keeping the hydrogen production within a desired range.
摘要翻译: 本发明涉及通过微生物发酵优化乙醇生产的方法,特别是包含CO的底物的微生物发酵方法,该方法包括监测微生物的氢产生,确定最佳的氢产生并响应于 改变氢气产生,从而将氢气产生保持在期望的范围内。
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公开(公告)号:US09617566B2
公开(公告)日:2017-04-11
申请号:US14329881
申请日:2014-07-11
发明人: Christophe Collet , Guy William Waters , Jason Carl Bromley , Justin Yi Yang , Jarod Nathan Wilson
IPC分类号: C12P7/06
摘要: Processes, as well as associated systems and computer program (software) products, are disclosed for the biological conversion of CO into desired end products such as ethanol. The control methodologies used for these processes can advantageously result in a reduced time required for a batch operation or other initial operating period, prior to achieving a continuous operation, which may be demarcated either by the addition of fresh culture medium at a defined flow rate or by another process initiation target. The control methodologies may alternatively, or in combination, improve a process performance parameter, such as productivity of the desired end product or bacterial growth rate, during this batch operation or other initial operating period.
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公开(公告)号:US20150072387A1
公开(公告)日:2015-03-12
申请号:US14324140
申请日:2014-07-04
摘要: A bioreactor system is provided for continuous fermentation of a gaseous substrate, said system comprising two or more primary bioreactors and one or more secondary bioreactors connected by a central bleed line. Further provided is a process for inoculating multiple bioreactors utilising a central bleed line, said process comprising passing fermentation broth from a first primary bioreactor to other primary bioreactors and/or secondary bioreactors via a central bleed line. Further provided is a process for maintaining stable fermentation of a gaseous substrate across multiple bioreactors, said process comprising providing fermentation broth from one or more operational primary bioreactors to one or more secondary bioreactors via a central bleed line.
摘要翻译: 提供生物反应器系统用于气态底物的连续发酵,所述系统包含两个或更多个初级生物反应器和一个或多个通过中心渗流线连接的二次生物反应器。 还提供了使用中央渗血线接种多个生物反应器的方法,所述方法包括通过中央渗血线将来自第一主要生物反应器的发酵液从其它主要生物反应器和/或二级生物反应器传播。 进一步提供了一种用于在多个生物反应器上维持气态底物的稳定发酵的方法,所述方法包括通过中央渗血线从一种或多种操作的初级生物反应器提供发酵液至一种或多种次生物反应器。
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公开(公告)号:US20130316424A1
公开(公告)日:2013-11-28
申请号:US13952651
申请日:2013-07-28
发明人: Sean Dennis Simpson , Christophe Collet , Michael Cockrem , Simon David Oakley , Michael Koepke
CPC分类号: C12P7/28 , C01B3/38 , C01B2203/0233 , C01B2203/0255 , C01B2203/0261 , C01B2203/0405 , C01B2203/0415 , C01B2203/043 , C01B2203/0475 , C01B2203/06 , C01B2203/1058 , C01B2203/86 , C12M21/12 , C12M29/26 , C12M41/34 , C12M43/04 , C12P1/04 , C12P7/00 , C12P7/065 , C12P7/08 , C12P7/54 , C12P7/62 , Y02E50/17 , Y02E50/343 , Y02P30/30 , Y02W10/37
摘要: The invention relates to methods of capturing carbon by microbial fermentation of a gaseous substrate comprising CO. The methods of the invention include converting CO to one or more products including alcohols and/or acids and optionally capturing CO2 to improve overall carbon capture. In certain aspects, the invention relates to processes for producing alcohols, particularly ethanol, from industrial waste streams, particularly steel mill off-gas.
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公开(公告)号:US10435722B2
公开(公告)日:2019-10-08
申请号:US15660948
申请日:2017-07-26
发明人: Sean Dennis Simpson , Christophe Collet , Michael Cockrem , Simon David Oakley , Michael Koepke
IPC分类号: C12P7/28 , C12M1/00 , C12M1/34 , C12P1/04 , C12P7/08 , C12P7/62 , C12P7/00 , C12P7/06 , C01B3/38 , C12P7/54
摘要: The invention relates to a method for producing products by microbial fermentation. The method comprises first converting a feed stream containing methane to a gaseous substrate comprising CO, of the invention include converting CO H2, and CO2 using a steam reforming zone and a water gas shift zone. The gaseous substrate is then converted to products such as alcohols and/or acids by to one or more products including alcohols and/or acids by fermentation using a carboxydotrophic microorganism.
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公开(公告)号:US09890399B2
公开(公告)日:2018-02-13
申请号:US14829597
申请日:2015-08-18
发明人: Sean Dennis Simpson , Christophe Collet , Michael Cockrem , Simon David Oakley , Michael Koepke
CPC分类号: C12P7/28 , C01B3/38 , C01B2203/0233 , C01B2203/0255 , C01B2203/0261 , C01B2203/0405 , C01B2203/0415 , C01B2203/043 , C01B2203/0475 , C01B2203/06 , C01B2203/1058 , C01B2203/86 , C12M21/12 , C12M29/26 , C12M41/34 , C12M43/04 , C12P1/04 , C12P7/00 , C12P7/065 , C12P7/08 , C12P7/54 , C12P7/62 , Y02E50/17 , Y02E50/343 , Y02P30/30 , Y02W10/37
摘要: Methods of capturing carbon by microbial fermentation of a gaseous substrate comprising CO. The methods include converting CO to one or more products including alcohols and/or acids and optionally capturing CO2 to improve overall carbon capture. In certain aspects, also disclosed are to processes for producing alcohols, particularly ethanol, from industrial waste streams, particularly steel mill off-gas.
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公开(公告)号:US20170321232A1
公开(公告)日:2017-11-09
申请号:US15660948
申请日:2017-07-26
发明人: Sean Dennis Simpson , Christophe Collet , Michael Cockrem , Simon David Oakley , Michael Koepke, JR.
摘要: The invention relates to a method for producing products by microbial fermentation. The method comprises first converting a feed stream containing methane to a gaseous substrate comprising CO, of the invention include converting CO H2, and CO2 using a steam reforming zone and a water gas shift zone. The gaseous substrate is then converted to products such as alcohols and/or acids byto one or more products including alcohols and/or acids by fermentation using a carboxydotrophic microorganism.
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公开(公告)号:US20170175064A1
公开(公告)日:2017-06-22
申请号:US15453878
申请日:2017-03-08
发明人: Christophe Collet , Guy William Waters , Jason Carl Bromley , Justin Yi Yang , Jarod Nathan Wilson
摘要: Processes, as well as associated systems and computer program (software) products, are disclosed for the biological conversion of CO into desired end products such as ethanol. The control methodologies used for these processes can advantageously result in a reduced time required for a batch operation or other initial operating period, prior to achieving a continuous operation, which may be demarcated either by the addition of fresh culture medium at a defined flow rate or by another process initiation target. The control methodologies may alternatively, or in combination, improve a process performance parameter, such as productivity of the desired end product or bacterial growth rate, during this batch operation or other initial operating period.
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