摘要:
There is provided herein cross-linked, phosphorescent micro- and nanoparticles and applications of those particles. The invention uses halogen-containing polymers and co-polymers (HCPs) as an encapsulation matrix for organic and organometallic phosphorescent compounds to form micro- or nanoparticles. The phosphorescence of these encapsulated phosphorescent particles is substantially unaffected by phosphorescence quenchers such as oxygen and water molecules at ambient conditions. The invention provides methods of making cross-linked phosphorescent particles. HCPs may be directly cross-linked through linking moieties that are a part of the polymer, or cross-linked through other separate bridging or cross-linking materials Cross-linked particles are more stable than the non-cross-linked counterparts and more resistant to temperature, surfactants, and organic solvents.
摘要:
There is provided a lateral flow diagnostic device that employs a phosphorescent particle. The particle includes, for example, an organic phosphorescent material encapsulated in a cross-linked halogen-containing polymeric matrix. The cross-linked halogen-containing polymeric matrix has at least one percent by mass weight of halogen atoms, and the cross-linked halogen-containing polymeric matrix shields the encapsulated phosphorescent material from phosphorescence quenchers.
摘要:
There is provided herein cross-linked, phosphorescent micro- and nano-particles and applications of those particles. The invention uses halogen-containing polymers and co-polymers (HCPs) as an encapsulation matrix for organic and organometallic phosphorescent compounds to form micro- or nano-particles. The phosphorescence of these encapsulated phosphorescent particles is substantially unaffected by phosphorescence quenchers such as oxygen and water molecules at ambient conditions. The invention provides methods of making cross-linked phosphorescent particles. HCPs may be directly cross-linked through linking moieties that are a part of the polymer, or cross-linked through other separate bridging or cross-linking materials Cross-linked particles are more stable than the non-cross-linked counterparts and more resistant to temperature, surfactants, and organic solvents.
摘要:
Various techniques for controlling the flow of a test sample through an electrochemical-based assay device are provided. The assay device contains a porous membrane provided with certain properties to selectively control the flow of a test sample to a detection working electrode. The detection working electrode communicates with affinity reagents, such as redox mediators and capture ligands. For instance, capture ligands that are specific binding members for the analyte of interest are applied to the detection electrode to serve as the primary location for detection of the analyte.
摘要:
There is provided herein cross-linked, phosphorescent micro- and nano-particles and applications of those particles. The invention uses halogen-containing polymers and co-polymers (HCPs) as an encapsulation matrix for organic and organometallic phosphorescent compounds to form micro- or nano-particles. The phosphorescence of these encapsulated phosphorescent particles is substantially unaffected by phosphorescence quenchers such as oxygen and water molecules at ambient conditions. The invention provides methods of making cross-linked phosphorescent particles. HCPs may be directly cross-linked through linking moieties that are a part of the polymer, or cross-linked through other separate bridging or cross-linking materials Cross-linked particles are more stable than the non-cross-linked counterparts and more resistant to temperature, surfactants, and organic solvents.
摘要:
A composition and method for encapsulating colorant molecules in polymeric particles are described. Colorant molecules, such as dye, are doped or embedded in a particle, at least in part, composed of a halogen-containing polymeric matrix that can effectively isolate the dye molecules from reaction with photo-oxidizing or reducing agents. The isolated colorant molecule is protected from photo-bleaching and other color degradation, and show superior photo-stability. The encapsulating polymer matrix can be cross-linked and can have a variety of surface functional groups, which may be adapted to help achieve either strong ionic or covalent binding to desired substrates. Also described are methods for producing protective particles, and ink mediums for applying the particles to substrates.
摘要:
A luminescent particle having a luminescent core structure formed from at least one type of luminescent metallic cluster complex and a shell that covers said core structure is described. The luminescent core structure includes one or more aggregates of metal cluster complexes. The shell has one or more layers of thin films formed predominately of organic or inorganic polymers, hydrid polymers, or combinations thereof. The luminescent particles can be adapted for optical detection or imaging applications. Methods of fabricating the various iterations of the luminescent particles are also provided.
摘要:
A composition and method for encapsulating colorant molecules in polymeric particles are described. Colorant molecules, such as dye, are doped or embedded in a particle, at least in part, composed of a halogen-containing polymeric matrix that can effectively isolate the dye molecules from reaction with photo-oxidizing or reducing agents. The isolated colorant molecule is protected from photo-bleaching and other color degradation, and show superior photo-stability. The encapsulating polymer matrix can be cross-linked and can have a variety of surface functional groups, which may be adapted to help achieve either strong ionic or covalent binding to desired substrates. Also described are methods for producing protective particles, and ink mediums for applying the particles to substrates.
摘要:
A composition and method for encapsulating colorant molecules in polymeric particles are described. Colorant molecules, such as dye, are doped or embedded in a particle, at least in part, composed of a halogen-containing polymeric matrix that can effectively isolate the dye molecules from reaction with photo-oxidizing or reducing agents. The isolated colorant molecule is protected from photo-bleaching and other color degradation, and show superior photo-stability. The encapsulating polymer matrix can be cross-linked and can have a variety of surface functional groups, which may be adapted to help achieve either strong ionic or covalent binding to desired substrates. Also described are methods for producing protective particles, and ink mediums for applying the particles to substrates.
摘要:
The invention involves encapsulation of phosphorescent molecules in polymeric matrices to prevent phosphorescence quenching. Specifically, polymers containing a significant portion of halogens have been found to be good matrices for encapsulation of phosphorescent molecules to provide strong phosphorescence at ambient conditions. Those encapsulated phosphorescent molecules can find a wide variety of applications for detection of many species, including biological and chemical molecules as well as micro-organisms.