Polymeric matrices for the encapsulation of phosphorescent molecules for analytical applications
    1.
    发明申请
    Polymeric matrices for the encapsulation of phosphorescent molecules for analytical applications 有权
    用于分析应用的磷光分子封装的聚合物基质

    公开(公告)号:US20050244643A1

    公开(公告)日:2005-11-03

    申请号:US10837093

    申请日:2004-04-30

    申请人: Xuedong Song Bin Wu

    发明人: Xuedong Song Bin Wu

    摘要: The invention involves encapsulation of phosphorescent molecules in polymeric matrices to prevent phosphorescence quenching. Specifically, polymers containing a significant portion of halogens have been found to be good matrices for encapsulation of phosphorescent molecules to provide strong phosphorescence at ambient conditions. Those encapsulated phosphorescent molecules can find a wide variety of applications for detection of many species, including biological and chemical molecules as well as micro-organisms.

    摘要翻译: 本发明涉及将磷光分子封装在聚合物基质中以防止磷光猝灭。 具体地,已经发现含有相当大部分卤素的聚合物是用于封装磷光分子的良好基质,以在环境条件下提供强磷光。 这些包封的磷光分子可以发现多种用于检测许多物种的应用,包括生物和化学分子以及微生物。

    CROSS-LINKED ENCAPSULATED PHOSPHORSCENT MOLECULES
    2.
    发明申请
    CROSS-LINKED ENCAPSULATED PHOSPHORSCENT MOLECULES 有权
    交联粘附的磷光体分子

    公开(公告)号:US20090127509A1

    公开(公告)日:2009-05-21

    申请号:US11772499

    申请日:2007-07-02

    IPC分类号: C09K11/02

    摘要: There is provided herein cross-linked, phosphorescent micro- and nanoparticles and applications of those particles. The invention uses halogen-containing polymers and co-polymers (HCPs) as an encapsulation matrix for organic and organometallic phosphorescent compounds to form micro- or nanoparticles. The phosphorescence of these encapsulated phosphorescent particles is substantially unaffected by phosphorescence quenchers such as oxygen and water molecules at ambient conditions. The invention provides methods of making cross-linked phosphorescent particles. HCPs may be directly cross-linked through linking moieties that are a part of the polymer, or cross-linked through other separate bridging or cross-linking materials Cross-linked particles are more stable than the non-cross-linked counterparts and more resistant to temperature, surfactants, and organic solvents.

    摘要翻译: 本文提供了交联的磷光微粒和纳米颗粒以及这些颗粒的应用。 本发明使用含卤聚合物和共聚物(HCP)作为有机和有机金属磷光化合物的包封基质以形成微米或纳米颗粒。 这些包封的磷光颗粒的磷光在环境条件下基本上不受磷光猝灭剂如氧和水分子的影响。 本发明提供制备交联磷光颗粒的方法。 HCP可以通过作为聚合物的一部分的连接部分直接交联,或者通过其它单独的桥连或交联材料交联。交联颗粒比非交联对应物更稳定,并且更耐抗 温度,表面活性剂和有机溶剂。

    Polymeric matrices for the encapsulation of phosphorescent molecules for analytical applications
    3.
    发明授权
    Polymeric matrices for the encapsulation of phosphorescent molecules for analytical applications 有权
    用于分析应用的磷光分子封装的聚合物基质

    公开(公告)号:US07247375B2

    公开(公告)日:2007-07-24

    申请号:US10837093

    申请日:2004-04-30

    申请人: Xuedong Song Bin Wu

    发明人: Xuedong Song Bin Wu

    IPC分类号: B32B5/16

    摘要: The invention involves encapsulation of phosphorescent molecules in polymeric matrices to prevent phosphorescence quenching. Specifically, polymers containing a significant portion of halogens have been found to be good matrices for encapsulation of phosphorescent molecules to provide strong phosphorescence at ambient conditions. Those encapsulated phosphorescent molecules can find a wide variety of applications for detection of many species, including biological and chemical molecules as well as micro-organisms.

    摘要翻译: 本发明涉及将磷光分子封装在聚合物基质中以防止磷光猝灭。 具体地,已经发现含有相当大部分卤素的聚合物是用于封装磷光分子的良好基质,以在环境条件下提供强磷光。 这些包封的磷光分子可以发现多种用于检测许多物种的应用,包括生物和化学分子以及微生物。

    Cross-linked encapsulated phosphorescent molecules
    4.
    发明授权
    Cross-linked encapsulated phosphorescent molecules 有权
    交联包封的磷光分子

    公开(公告)号:US07238301B2

    公开(公告)日:2007-07-03

    申请号:US10879933

    申请日:2004-06-29

    IPC分类号: C09K11/06 C09K11/02

    摘要: There is provided herein cross-linked, phosphorescent micro- and nano-particles and applications of those particles. The invention uses halogen-containing polymers and co-polymers (HCPs) as an encapsulation matrix for organic and organometallic phosphorescent compounds to form micro- or nano-particles. The phosphorescence of these encapsulated phosphorescent particles is substantially unaffected by phosphorescence quenchers such as oxygen and water molecules at ambient conditions. The invention provides methods of making cross-linked phosphorescent particles. HCPs may be directly cross-linked through linking moieties that are a part of the polymer, or cross-linked through other separate bridging or cross-linking materials Cross-linked particles are more stable than the non-cross-linked counterparts and more resistant to temperature, surfactants, and organic solvents.

    摘要翻译: 本文提供了交联的磷光微粒和纳米颗粒以及这些颗粒的应用。 本发明使用含卤聚合物和共聚物(HCP)作为有机和有机金属磷光化合物的包封基质以形成微米或纳米颗粒。 这些包封的磷光颗粒的磷光在环境条件下基本上不受磷光猝灭剂如氧和水分子的影响。 本发明提供制备交联磷光颗粒的方法。 HCP可以通过作为聚合物的一部分的连接部分直接交联,或者通过其它单独的桥连或交联材料交联。交联颗粒比非交联对应物更稳定,并且更耐抗 温度,表面活性剂和有机溶剂。

    Cross-linked encapsulated phosphorescent molecules
    5.
    发明申请
    Cross-linked encapsulated phosphorescent molecules 有权
    交联包封的磷光分子

    公开(公告)号:US20050285082A1

    公开(公告)日:2005-12-29

    申请号:US10879933

    申请日:2004-06-29

    摘要: There is provided herein cross-linked, phosphorescent micro- and nano-particles and applications of those particles. The invention uses halogen-containing polymers and co-polymers (HCPs) as an encapsulation matrix for organic and organometallic phosphorescent compounds to form micro- or nano-particles. The phosphorescence of these encapsulated phosphorescent particles is substantially unaffected by phosphorescence quenchers such as oxygen and water molecules at ambient conditions. The invention provides methods of making cross-linked phosphorescent particles. HCPs may be directly cross-linked through linking moieties that are a part of the polymer, or cross-linked through other separate bridging or cross-linking materials Cross-linked particles are more stable than the non-cross-linked counterparts and more resistant to temperature, surfactants, and organic solvents.

    摘要翻译: 本文提供了交联的磷光微粒和纳米颗粒以及这些颗粒的应用。 本发明使用含卤聚合物和共聚物(HCP)作为有机和有机金属磷光化合物的包封基质以形成微米或纳米颗粒。 这些包封的磷光颗粒的磷光在环境条件下基本上不受磷光猝灭剂如氧和水分子的影响。 本发明提供制备交联磷光颗粒的方法。 HCP可以通过作为聚合物的一部分的连接部分直接交联,或者通过其它单独的桥连或交联材料交联。交联颗粒比非交联对应物更稳定,并且更耐抗 温度,表面活性剂和有机溶剂。

    Multi-layered devices for analyte detection
    9.
    发明授权
    Multi-layered devices for analyte detection 有权
    用于分析物检测的多层设备

    公开(公告)号:US09103796B2

    公开(公告)日:2015-08-11

    申请号:US11956420

    申请日:2007-12-14

    申请人: Xuedong Song

    发明人: Xuedong Song

    IPC分类号: G01N21/78 G01N33/52 G01N21/77

    摘要: A multi-layered device for detecting the presence or absence of an analyte within a test sample is described. The device includes a sensing layer and a control layer. The sensing layer is configured to support a reaction so as to exhibit a signal indicative of the presence or absence of the analyte in the test sample. The control layer is in fluid communication with and vertically adjacent to the sensing layer and includes a reagent capable of inhibiting the reaction and/or other unwanted side reactions at the sensing layer after a certain period of time by diffusive movement of the reagent from the control layer to the sensing layer.

    摘要翻译: 描述了用于检测测试样品中有无分析物的多层装置。 该装置包括感测层和控制层。 感测层被配置为支持反应以便表现出指示测试样品中分析物的存在或不存在的信号。 控制层与感测层流体连通并垂直相邻,并且包括能够在一定时间段之后通过试剂从控制器的扩散运动来抑制反应和/或感测层处的其它不期望的副反应的试剂 层到感测层。

    Dehydration sensors having polymeric base-buffered inks
    10.
    发明授权
    Dehydration sensors having polymeric base-buffered inks 有权
    具有聚合物基底缓冲油墨的脱水传感器

    公开(公告)号:US08742198B2

    公开(公告)日:2014-06-03

    申请号:US12957542

    申请日:2010-12-01

    IPC分类号: A61F13/15

    摘要: A dehydration sensor having a stable, printable, buffered-ink composition that enables one to miniaturize the detection zone and permits both buffer and indicator dye to be applied in the same area of a detection zone, without need for a conventional, large buffer pad region. The ink composition includes a weak polymeric base as its primary buffering agent.

    摘要翻译: 一种具有稳定的可印刷缓冲油墨组合物的脱水传感器,其使得能够使检测区域小型化并且允许将缓冲液和指示剂染料施加在检测区域的相同区域中,而不需要常规的大的缓冲垫区域 。 油墨组合物包括弱聚合物基料作为其主要缓冲剂。