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公开(公告)号：US07335164B2
公开(公告)日：2008-02-26
申请号：US09841451
申请日：2001-04-24
申请人： Leslie E. Mace , Lawrence L. Labuda , Perry R. Blazewicz , David R. Rich , Michael B. Jaffe , Joseph A. Orr , Scott A. Kofoed
发明人： Leslie E. Mace , Lawrence L. Labuda , Perry R. Blazewicz , David R. Rich , Michael B. Jaffe , Joseph A. Orr , Scott A. Kofoed
CPC分类号： G01N21/6428 , A61B5/083 , A61B5/0833 , A61B5/087 , A61B5/097 , G01F1/40 , G01F1/42 , G01N21/0303 , G01N21/05 , G01N21/3504 , G01N21/645 , G01N33/0036 , G01N33/497 , G01N2001/2244 , G01N2021/6432
摘要： An integrated airway adapter capable of monitoring any combination of respiratory flow, O2 concentration, and concentrations of one or more of CO2, N2O, and an anesthetic agent in real time, breath by breath. Respiratory flow may be monitored with differential pressure flow meters under diverse inlet conditions through improved sensor configurations which minimize phase lag and dead space within the airway. Molecular oxygen concentration may be monitored by way of luminescence quenching techniques. Infrared absorption techniques may be used to monitor one or more of CO2, N2O, and anesthetic agents.
摘要翻译： 能够监测呼吸流量O 2浓度的任何组合以及CO 2 2 N 2 N 2 N 2中的一种或多种的浓度的组合气道适配器， O和麻醉剂实时呼吸。 可以通过改进的传感器配置在不同入口条件下通过差压流量计监测呼吸流量，从而最小化气道内的相位滞后和死区。 可以通过发光淬灭技术监测分子氧浓度。 红外吸收技术可用于监测一种或多种CO 2，N 2 O和麻醉剂。
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公开(公告)号：US08096297B2
公开(公告)日：2012-01-17
申请号：US12702596
申请日：2010-02-09
CPC分类号： A61B5/029 , A61B5/0836 , A61M16/0045 , A61M16/0833 , A61M2016/0036 , A61M2230/432 , G01N33/004 , Y02A50/243
摘要： Apparatus and methods for non-invasively determining cardiac output using partial re-breathing techniques are disclosed in which the apparatus is constructed with an instantaneously adjustable deadspace for accommodating differences in breathing capacities of various patients. The apparatus is constructed of inexpensive elements, including a single two-way valve which renders the apparatus very simple to use and inexpensive so that the unit may be readily disposable. The method of the invention provides a novel means of estimating cardiac output based on alveolar CO2 values rather than end-tidal CO2 values as previously practiced. A program for calculating cardiac output is also disclosed.
摘要翻译： 公开了使用部分再呼吸技术非侵入性地确定心输出量的装置和方法，其中该装置构造有瞬时可调的死区，以适应各种患者的呼吸能力差异。 该设备由便宜的元件构成，包括单个双向阀，其使得该设备使用起来非常简单且便宜，使得该单元可以容易地被一次性使用。 本发明的方法提供了一种基于肺泡二氧化碳值估计心输出量的新方法，而不是如先前所述的潮汐CO 2值。 还公开了一种用于计算心输出量的程序。
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公开(公告)号：US07686012B2
公开(公告)日：2010-03-30
申请号：US11120103
申请日：2005-05-02
CPC分类号： A61B5/029 , A61B5/0836 , A61M16/0045 , A61M16/0833 , A61M2016/0036 , A61M2230/432 , G01N33/004 , Y02A50/243
摘要： Apparatus and methods for non-invasively determining cardiac output using partial re-breathing techniques are disclosed in which the apparatus is constructed with an instantaneously adjustable deadspace for accommodating differences in breathing capacities of various patients. The apparatus is constructed of inexpensive elements, including a single two-way valve which renders the apparatus very simple to use and inexpensive so that the unit may be readily disposable. The method of the invention provides a novel means of estimating cardiac output based on alveolar CO2 values rather than end-tidal CO2 values as previously practiced. A program for calculating cardiac output is also disclosed.
摘要翻译： 公开了使用部分再呼吸技术非侵入性地确定心输出量的装置和方法，其中该装置构造有瞬时可调的死区，以适应各种患者的呼吸能力差异。 该设备由便宜的元件构成，包括单个双向阀，其使得该设备使用起来非常简单且便宜，使得该单元可以容易地被一次性使用。 本发明的方法提供了一种基于肺泡二氧化碳值估计心输出量的新方法，而不是如先前所述的潮汐CO 2值。 还公开了一种用于计算心输出量的程序。
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公开(公告)号：US07018340B2
公开(公告)日：2006-03-28
申请号：US10657577
申请日：2003-09-08
IPC分类号： A61B5/00
CPC分类号： A61B5/029 , A61B5/0836 , A61M16/0045 , A61M16/0833 , A61M2016/0036 , A61M2230/432 , G01N33/004 , Y02A50/243
摘要： Apparatus and methods for non-invasively determining the cardiac output or pulmonary capillary blood flow of a patient using partial re-breathing techniques. The apparatus includes a substantially instantaneously adjustable deadspace volume for accommodating differences in sizes or breathing capacities of various patients. The apparatus may be constructed of inexpensive elements, including one or more two-way valves, which render the apparatus very simple to use and inexpensive so that the unit may be employed as a disposable product. The method of the invention includes estimating the cardiac output or pulmonary capillary blood flow of a patient based on partial pressure of alveolar CO2, rather than on the partial pressure of end tidal CO2, as previously practiced. A computer program for calculating the cardiac output or pulmonary capillary blood flow of a patient is also disclosed.
摘要翻译： 使用部分再呼吸技术非侵入性地确定患者的心输出量或肺毛细血管血流量的装置和方法。 该装置包括基本上即时可调的死空间体积，用于适应各种患者的尺寸或呼吸能力的差异。 该设备可以由廉价的元件构成，包括一个或多个双向阀，这使得该设备使用起来非常简单并且便宜，使得该单元可以用作一次性产品。 本发明的方法包括基于肺泡CO 2 2的分压来估计患者的心输出量或肺毛细血管血流量，而不是基于潮气CO 2 2的分压， SUB>，如前所述。 还公开了一种用于计算患者的心输出量或肺毛细血管血流量的计算机程序。
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公开(公告)号：US06648832B2
公开(公告)日：2003-11-18
申请号：US09777629
申请日：2001-02-06
IPC分类号： A61B6500
CPC分类号： A61B5/029 , A61B5/0836 , A61M16/0045 , A61M16/0833 , A61M2016/0036 , A61M2230/432 , G01N33/004 , Y02A50/243
摘要： Apparatus and methods for non-invasively determining the cardiac output or pulmonary capillary blood flow of a patient using partial re-breathing techniques. The apparatus includes a substantially instantaneously adjustable deadspace volume for accommodating differences in sizes or breathing capacities of various patients. The apparatus may be constructed of inexpensive elements, including one or more two-way valves, which render the apparatus very simple to use and inexpensive so that the unit may be employed as a disposable product. The method of the invention includes estimating the cardiac output or pulmonary capillary blood flow of a patient based on partial pressure of alveolar CO2, rather than on the partial pressure of end tidal CO2, as previously practiced. A computer program for calculating the cardiac output or pulmonary capillary blood flow of a patient is also disclosed.
摘要翻译： 使用部分再呼吸技术非侵入性地确定患者的心输出量或肺毛细血管血流量的装置和方法。 该装置包括基本上即时可调的死空间体积，用于适应各种患者的尺寸或呼吸能力的差异。 该设备可以由廉价的元件构成，包括一个或多个双向阀，这使得该设备使用起来非常简单并且便宜，使得该单元可以用作一次性产品。 本发明的方法包括基于肺泡二氧化碳的分压来估计患者的心输出量或肺毛细血管血流量，而不是如先前所述的结束潮汐CO 2的分压。 还公开了一种用于计算患者的心输出量或肺毛细血管血流量的计算机程序。
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公开(公告)号：US06306098B1
公开(公告)日：2001-10-23
申请号：US08770138
申请日：1996-12-19
IPC分类号： A61B1500
CPC分类号： A61B5/029 , A61B5/0836 , A61M16/0045 , A61M16/0833 , A61M2016/0036 , A61M2230/432 , G01N33/004 , Y02A50/243
摘要： Apparatus and methods for non-invasively determining cardiac output using partial re-breathing techniques are disclosed in which the apparatus is constructed with an instantaneously adjustable deadspace for accommodating differences in breathing capacities of various patients. The apparatus is constructed of inexpensive elements, including a single two-way valve which renders the apparatus very simple to use and inexpensive so that the unit may be readily disposable. The method of the invention provides a novel means of estimating cardiac output based on alveolar CO2 values rather than end-tidal CO2 values as previously practiced. A program for calculating cardiac output is also disclosed.
摘要翻译： 公开了使用部分再呼吸技术非侵入性地确定心输出量的装置和方法，其中该装置构造有瞬时可调的死区，以适应各种患者的呼吸能力差异。 该设备由便宜的元件构成，包括单个双向阀，其使得该设备使用起来非常简单且便宜，使得该单元可以容易地被一次性使用。 本发明的方法提供了一种基于肺泡二氧化碳值估计心输出量的新方法，而不是如先前所述的潮汐CO 2值。 还公开了一种用于计算心输出量的程序。
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公开(公告)号：US06227196B1
公开(公告)日：2001-05-08
申请号：US09262510
申请日：1999-03-02
IPC分类号： A61M1600
CPC分类号： A61B5/029 , A61B5/0836 , A61M16/0045 , A61M16/0833 , A61M2016/0036 , A61M2230/432 , G01N33/004 , Y02A50/243
摘要： Apparatus and methods for non-invasively determining the cardiac output or pulmonary capillary blood flow of a patient using partial re-breathing techniques. The apparatus includes a substantially instantaneously adjustable deadspace volume for accommodating differences in sizes or breathing capacities of various patients. The apparatus may be constructed of inexpensive elements, including one or more two-way valves, which render the apparatus very simple to use and inexpensive so that the unit may be employed as a disposable product. The method of the invention includes estimating the cardiac output or pulmonary capillary blood flow of a patient based on partial pressure of alveolar CO2 rather than on the partial pressure of end tidal CO2, as previously practiced. A computer program for calculating the cardiac output or pulmonary capillary blood flow of a patient is also disclosed.
摘要翻译： 使用部分再呼吸技术非侵入性地确定患者的心输出量或肺毛细血管血流量的装置和方法。 该装置包括基本上即时可调的死空间体积，用于适应各种患者的尺寸或呼吸能力的差异。 该设备可以由廉价的元件构成，包括一个或多个双向阀，这使得该设备使用起来非常简单并且便宜，使得该单元可以用作一次性产品。 本发明的方法包括如前所述，基于肺泡CO 2的分压来估计患者的心输出量或肺毛细血管血流量，而不是如结束潮汐CO 2的分压。 还公开了一种用于计算患者的心输出量或肺毛细血管血流量的计算机程序。
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公开(公告)号：US06908438B2
公开(公告)日：2005-06-21
申请号：US10657909
申请日：2003-09-08
IPC分类号： A61B5/026 , A61B5/029 , A61B5/08 , A61B5/083 , A61B5/087 , A61B5/097 , A61B10/00 , A61M16/00 , G01N33/00
CPC分类号： A61B5/029 , A61B5/0836 , A61M16/0045 , A61M16/0833 , A61M2016/0036 , A61M2230/432 , G01N33/004 , Y02A50/243
摘要： Apparatus and methods for non-invasively determining cardiac output using partial re-breathing techniques are disclosed in which the apparatus is constructed with an instantaneously adjustable deadspace for accommodating differences in breathing capacities of various patients. The apparatus is constructed of inexpensive elements, including a single two-way valve which renders the apparatus very simple to use and inexpensive so that the unit may be readily disposable. The method of the invention provides a novel means of estimating cardiac output based on alveolar CO2 values rather than end-tidal CO2 values as previously practiced. A program for calculating cardiac output is also disclosed.
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公开(公告)号：US06648831B2
公开(公告)日：2003-11-18
申请号：US09767363
申请日：2001-01-23
IPC分类号： A61B0500
CPC分类号： A61B5/029 , A61B5/0836 , A61M16/0045 , A61M16/0833 , A61M2016/0036 , A61M2230/432 , G01N33/004 , Y02A50/243
摘要： Apparatus and methods for non-invasively determining cardiac output using partial re-breathing techniques are disclosed in which the apparatus is constructed with an instantaneously adjustable deadspace for accommodating differences in breathing capacities of various patients. The apparatus is constructed of inexpensive elements, including a single two-way valve which renders the apparatus very simple to use and inexpensive so that the unit may be readily disposable. The method of the invention provides a novel means of estimating cardiac output based on alveolar CO2 values rather than end-tidal CO2 values as previously practiced. A program for calculating cardiac output is also disclosed.
摘要翻译： 公开了使用部分再呼吸技术非侵入性地确定心输出量的装置和方法，其中该装置构造有瞬时可调的死区，以适应各种患者的呼吸能力差异。 该设备由便宜的元件构成，包括单个双向阀，其使得该设备使用起来非常简单且便宜，使得该单元可以容易地被一次性使用。 本发明的方法提供了一种基于肺泡二氧化碳值估计心输出量的新方法，而不是如先前所述的潮汐CO 2值。 还公开了一种用于计算心输出量的程序。
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公开(公告)号：US5789660A
公开(公告)日：1998-08-04
申请号：US680492
申请日：1996-07-15
申请人： Scott A. Kofoed , Joseph A. Orr , David R. Rich
发明人： Scott A. Kofoed , Joseph A. Orr , David R. Rich
摘要： An integrated airway adapter capable of monitoring CO.sub.2 concentration in real time, breath by breath using infrared absorption techniques and monitoring respiratory flow with differential pressure flowmeters under diverse inlet conditions through improved sensor configurations which minimize phase lag and dead space within the airway adapter.
摘要翻译： 一种集成气道适配器，能够实时监测二氧化碳浓度，使用红外吸收技术进行呼吸呼吸，并通过改进的传感器配置在不同入口条件下通过差压流量计监测呼吸流量，从而最大限度地减少气道适配器内的相位滞后和死区。
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