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公开(公告)号：US20050261668A1
公开(公告)日：2005-11-24
申请号：US10403421
申请日：2003-03-28
申请人： Linda Mosack , Daniel Hook , George Grobe , Matthew Jonasse
发明人： Linda Mosack , Daniel Hook , George Grobe , Matthew Jonasse
CPC分类号： A61K9/0051
摘要： A drug delivery device includes a drug core having a pharmaceutically active agent, a holder that holds the drug core and is made of a material impermeable to passage of the active agent; and a tab for attaching the device to eye tissue. A surface of the holder is plasma treated and adhered to at least one of the drug core and the tab. The device is preferably designed for placing in the eye, such as implanting the device using the tab, so the active agent is released in a sustained manner to the eye.
摘要翻译： 药物递送装置包括具有药物活性剂的药物核心，保持药物核心并由不透过活性剂通过的材料制成的保持器; 以及用于将装置附接到眼睛组织的突片。 保持器的表面被等离子体处理并粘附到药物核心和突片中的至少一个。 该装置优选地设计用于放置在眼睛中，例如使用突片植入装置，使得活性剂以持续的方式释放到眼睛。
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公开(公告)号：US20060074182A1
公开(公告)日：2006-04-06
申请号：US10955463
申请日：2004-09-30
申请人： Richard King , George Grobe
发明人： Richard King , George Grobe
IPC分类号： C08G67/02
CPC分类号： A61L31/145 , A61L15/60 , A61L26/008 , A61L27/52 , C08L71/02
摘要： The invention provides a hydrogel composition comprising water and a hydrophilic polymer, wherein the hydrogel composition has (a) an ultimate tensile strength of about 10 kPa or more, (b) a compressive strength of about 70 kPa or more, or (c) an ultimate tensile strength of about 10 kPa or more and a compressive strength of about 70 kPa or more. The invention further provides methods for producing a hydrogel composition.
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公开(公告)号：US20060068224A1
公开(公告)日：2006-03-30
申请号：US10957292
申请日：2004-09-30
申请人： George Grobe , Janine Orban , Mark Heldreth , Richard Tarr , Don Paquin , Jonathon Spanyer
发明人： George Grobe , Janine Orban , Mark Heldreth , Richard Tarr , Don Paquin , Jonathon Spanyer
摘要： The present invention provides a halogen coated biomedical device and a method for producing the device. The method generally involves generating a plasma that affects the release of a halogen species from a source. The halogen reacts with the surface of the biomedical device to form a halogen coating.
摘要翻译： 本发明提供一种卤素涂覆的生物医学装置及其制造方法。 该方法通常涉及产生影响卤素物质从源的释放的等离子体。 卤素与生物医学装置的表面反应形成卤素涂层。
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公开(公告)号：US20070009505A1
公开(公告)日：2007-01-11
申请号：US11428674
申请日：2006-07-05
申请人： Edward Arscott , Irina Ganopolsky , George Grobe , Mark Heldreth , Joseph LiBrizzi , Hugo Pedrozo
发明人： Edward Arscott , Irina Ganopolsky , George Grobe , Mark Heldreth , Joseph LiBrizzi , Hugo Pedrozo
摘要： The present disclosure is directed to a cleansing solution and system for administering the cleansing solution to decontaminate a wound surface. A method and kit for decontaminating a wound surface is also provided.
摘要翻译： 本公开涉及用于施用清洁溶液以净化伤口表面的清洁溶液和系统。 还提供了用于净化伤口表面的方法和试剂盒。
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公开(公告)号：US20060246250A1
公开(公告)日：2006-11-02
申请号：US11475588
申请日：2006-06-27
申请人： George Grobe
发明人： George Grobe
IPC分类号： B32B3/02
CPC分类号： C08J7/123 , C08J7/12 , G02B1/043 , Y10T428/21 , Y10T428/3154 , C08L83/08 , C08L45/00
摘要： Hydrogen-plasma modification of fluorinated polymers reduces the surface chemistry of this polymer removing fluorine, leaving behind a carbon-enriched surface that is further plasma processed into a hydrophilic surface for a lens material to be inserted into the ocular environment.
摘要翻译： 氟化聚合物的氢 - 等离子体改性降低了该聚合物去除氟的表面化学性质，留下了富含碳的表面，其进一步等离子体处理成亲水表面，用于透镜材料插入到眼睛环境中。
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公开(公告)号：US20050045589A1
公开(公告)日：2005-03-03
申请号：US10647556
申请日：2003-08-25
CPC分类号： B29D11/0024 , A61F2/0077 , A61F2/16 , A61L27/50 , A61L2400/18 , A61L2430/16 , B29C59/14 , B29D11/00076 , B29L2011/0041 , C08J7/123 , H01J37/32532 , H05H1/24
摘要： Intraocular lenses or contact lenses 20 are placed on a lower spindle 34 and held there by a vacuum in conduit 34. Noble and reactive gases 56, 58 are introduced and a voltage is applied across upper spindle 32 and lower spindle 34 to plasma treat one surface of the lens. The lens is transferred to the other spindle and the process is repeated.
摘要翻译： 将眼内透镜或隐形眼镜20放置在下心轴34上并通过管道34中的真空保持在其上。引入高贵气体和反应性气体56,58，并且在上心轴32和下心轴34上施加电压以等离子体处理一个表面 的镜头。 镜头转移到另一个主轴，重复该过程。
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