公开(公告)号：US07749260B2

公开(公告)日：2010-07-06

申请号：US11299284

申请日：2005-12-09

申请人： Luiz B. Da Silva ,  George Choi ,  Joseph Neev

发明人： Luiz B. Da Silva ,  George Choi ,  Joseph Neev

IPC分类号： A61F7/00

CPC分类号： A61B18/082 ,  A61B2017/00734 ,  A61B2017/00761 ,  A61B2018/00005 ,  A61B2018/0047 ,  A61B2018/00714 ,  A61B2018/00761 ,  A61B2018/00791

摘要： Devices and methods for the treatment of skin conditions and lesions are disclosed herein. One aspect of the invention is a compact hand held device that can be safely used by those suffering from skin conditions, such as acne, warts, cold blisters, blemished skin, or fine wrinkles. The devices described herein employ the application of heat for the treatment of skin conditions and lesions. Typically, the peak temperatures employed are about 70° C. to about 400° C. by the devices, are achieved in less than about 1 second, and maintained for less than about 1 second. In some embodiments, the skin surface is heated with heat pulses. Thermal conduction transfers heat from the device to the skin and causes a biological response that accelerates acne clearing, treats blemished skin, itching, or fine wrinkles. The total heat transferred is low enough to prevent burns.

摘要翻译： 本文公开了用于治疗皮肤病况和损伤的装置和方法。 本发明的一个方面是紧凑的手持装置，其可以被患有皮肤状况的人安全地使用，例如痤疮，疣，冷水泡，瑕疵的皮肤或细皱纹。 本文描述的装置使用热量来治疗皮肤病症和损伤。 通常，所用装置的峰值温度为约70℃至约400℃，在小于约1秒钟内实现，并保持少于约1秒。 在一些实施方案中，用热脉冲加热皮肤表面。 热传导将热量从设备传递到皮肤，并引起加速痤疮清除，治疗瑕疵皮肤，瘙痒或细皱纹的生物反应。 传热的总热量足够低以防止灼伤。

公开(公告)号：US07494492B2

公开(公告)日：2009-02-24

申请号：US11216595

申请日：2005-08-30

申请人： Luiz B. Da Silva ,  George Choi

发明人： Luiz B. Da Silva ,  George Choi

IPC分类号： A61B18/08

CPC分类号： A61B18/082 ,  A61B2017/00734 ,  A61B2017/00761

摘要： A compact hand held device is provided that can be safely used by those suffering from acne, blemished skin or fine wrinkles. The hand held device includes an on/off switch and a button that pulses the device when it is placed on the target site. A battery within the device powers a circuit board and drives a short pulse of current through a heating element, which heats up to approximately 300° C. in less than 0.1 sec. Thermal conduction transfers the heat to the skin and causes a biological response that accelerates acne clearing, treats blemished skin or fine wrinkles. The total heat transferred is low enough to prevent burns. Application of acne treatment creams and gels further accelerates treatment

摘要翻译： 提供了一个紧凑的手持装置，可以被那些患有痤疮，瑕疵的皮肤或细皱纹的人安全使用。 手持设备包括一个开/关开关和一个按钮，当设备放置在目标站点上时，该按钮将脉冲。 设备内的电池为电路板供电，并通过加热元件驱动短脉冲电流，加热元件在小于0.1秒内加热至约300°C。 热传导将热量转移到皮肤，并引起加速痤疮清除，治疗瑕疵皮肤或细皱纹的生物反应。 传热的总热量足够低以防止灼伤。 痤疮治疗霜和凝胶的应用进一步加速治疗

公开(公告)号：US20080047566A1

公开(公告)日：2008-02-28

申请号：US11859713

申请日：2007-09-21

申请人： Anant Hegde ,  George Choi ,  Wally Buch ,  Kasey Li

发明人： Anant Hegde ,  George Choi ,  Wally Buch ,  Kasey Li

IPC分类号： A61F5/56

CPC分类号： A61L31/125 ,  A61B2017/248 ,  A61C7/00 ,  A61F2/00 ,  A61F5/56 ,  A61F5/566 ,  A61F2210/0023 ,  A61L31/14 ,  A61N1/0517 ,  A61N1/0519 ,  A61N1/0548 ,  A61N1/3601 ,  Y10S602/902

摘要： An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods of using the device are also disclosed. The airway implant device comprises a deformable element to control the opening of an air passageway. Preferably the deformable element is an electroactive polymer element. Energizing of the electroactive polymer element provides support for the walls of an air passageway, when the walls collapse, and thus, completely or partially opens the air passageway. Methods of treating airway disorders such as sleep apnea and snoring with the airway implant device are disclosed herein.

摘要翻译： 公开了一种用于在空气通道中保持和/或形成开口的气道植入装置。 还公开了使用该装置的方法。 气道植入装置包括可变形元件以控制空气通道的开口。 优选地，可变形元件是电活性聚合物元件。 电活性聚合物元件的通电为空气通道的壁提供支撑，当壁崩溃时，从而完全或部分地打开空气通道。 本文公开了用气道植入装置处理呼吸道疾病如睡眠呼吸暂停和打鼾的方法。

公开(公告)号：US20080041398A1

公开(公告)日：2008-02-21

申请号：US11847271

申请日：2007-08-29

申请人： Anant Hegde ,  Kasey Li ,  Nikhil Bhat ,  Christopher Bagley ,  Casidy Hallsten ,  George Choi ,  Doyeon Kim

发明人： Anant Hegde ,  Kasey Li ,  Nikhil Bhat ,  Christopher Bagley ,  Casidy Hallsten ,  George Choi ,  Doyeon Kim

IPC分类号： A61F5/56

CPC分类号： A61F5/56 ,  A61B2017/248 ,  A61F5/566 ,  A61F2210/0038 ,  Y10S602/902

摘要： An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods of using the device are also disclosed. The implant is an implant for stabilizing the tongue, the implant having an anchoring portion for securing a first end of the implant with the mandibula; a control portion connected with the anchoring portion, configured for selectively activating the implant; a flexible portion connected at its proximal end with the control portion, where the flexible portion has three-dimensional flexibility in a first state and where the flexible portion has a lesser three-dimensional flexibility in a second state, and where the flexible portion is selectively switchable between the first and second state by the control portion; an anchoring portion for connecting the implant with the base of the tongue connected with the flexible portion, and a latch mechanism coupled with the control portion and configured to maintain the flexible portion in either of the first and second states. Methods of treating airway disorders such as sleep apnea and snoring with the airway implant device are disclosed herein.

摘要翻译： 公开了一种用于在空气通道中保持和/或形成开口的气道植入装置。 还公开了使用该装置的方法。 植入物是用于稳定舌头的植入物，所述植入物具有用于固定植入物的第一端与下颌骨的锚定部分; 与所述锚定部分连接的控制部分，被配置为选择性地启动所述植入物; 其柔性部分在其近端连接有控制部分，其中柔性部分在第一状态下具有三维柔性，并且柔性部分在第二状态下具有较小的三维柔性，并且其中柔性部分是选择性的 通过控制部在第一状态和第二状态之间切换; 用于将植入物与与柔性部分连接的舌片的基部连接的锚定部分，以及与控制部分联接并被配置为将柔性部分保持在第一状态和第二状态中的任一状态的闩锁机构。 本文公开了用气道植入装置处理呼吸道疾病如睡眠呼吸暂停和打鼾的方法。

公开(公告)号：US20070016061A1

公开(公告)日：2007-01-18

申请号：US11415560

申请日：2006-05-01

申请人： Luiz Da Silva ,  George Choi

发明人： Luiz Da Silva ,  George Choi

IPC分类号： A61B8/14

CPC分类号： A61B8/0858 ,  A61B5/4869 ,  A61B5/4872 ,  A61B8/585

摘要： A system for evaluating health, wellness and fitness, and in particular, to a system that uses an ultrasound transducer to accurately measure fat thickness at a plurality of sites on the human body, records these measurements for long term monitoring, and based on the plurality of measurements calculates the total body composition. The system includes a central control unit to analyze the measurement and display the results in a variety of formats.

摘要翻译： 用于评估健康，健康和适应性的系统，特别是使用超声换能器精确测量人体上多个部位的脂肪厚度的系统，记录这些测量用于长期监测，并且基于多个 的测量计算总身体组成。 该系统包括用于分析测量并以各种格式显示结果的中央控制单元。

公开(公告)号：US20060060207A1

公开(公告)日：2006-03-23

申请号：US10946435

申请日：2004-09-21

申请人： Anant Hegde ,  George Choi ,  Wally Buch

发明人： Anant Hegde ,  George Choi ,  Wally Buch

IPC分类号： A61F5/56

CPC分类号： A61L31/125 ,  A61B2017/248 ,  A61C7/00 ,  A61F2/00 ,  A61F5/56 ,  A61F5/566 ,  A61F2210/0023 ,  A61L31/14 ,  A61N1/0517 ,  A61N1/0519 ,  A61N1/0548 ,  A61N1/3601 ,  Y10S602/902

摘要： A system and device for maintaining and/or creating patency in airways is disclosed. The methods of using the system and device are also disclosed. The system includes a power source that energizes a electro-active polymer implant. The energized polymer implant provides stiffness and shape to the airway, thereby minimizing collapse or deformation of the airway. A method of making the device is also disclosed.

摘要翻译： 公开了一种用于在气道中维持和/或产生通畅的系统和装置。 还公开了使用该系统和装置的方法。 该系统包括为电活性聚合物植入物通电的电源。 通电的聚合物植入物为气道提供刚度和形状，从而最小化气道的塌陷或变形。 还公开了制造该器件的方法。

公开(公告)号：US20060047180A1

公开(公告)日：2006-03-02

申请号：US11213438

申请日：2005-08-25

申请人： Anant Hegde ,  George Choi ,  Wally Buch

发明人： Anant Hegde ,  George Choi ,  Wally Buch

IPC分类号： A61F2/02

CPC分类号： A61F2/0036 ,  A61F2/0004 ,  A61F2/0022 ,  A61F2/0031 ,  A61L27/14 ,  A61L27/50 ,  A61N1/0512 ,  A61N1/36007

摘要： A biologically implantable artificial sphincter system and methods of using the same is disclosed. The artificial sphincter system disclosed herein comprises a support and an electroactive polymer element, both of which are adapted and configured to open and/or close a body cavity. The artificial sphincter systems are useful in the treatment of urinary incontinence, fecal incontinence, and reflux disorders. The implanted artificial sphincter can also provide a signal to the recipient to urinate or defecate.

摘要翻译： 公开了一种生物可植入人造括约肌系统及其使用方法。 本文公开的人造括约肌系统包括支撑体和电活性聚合物元件，两者都适于和构造成打开和/或闭合体腔。 人造括约肌系统可用于治疗尿失禁，大便失禁和反流疾病。 植入的人造括约肌还可以向接受者提供小便或排便的信号。

公开(公告)号：US20130104796A1

公开(公告)日：2013-05-02

申请号：US13665856

申请日：2012-10-31

申请人： Nikhil Bhat ,  George Choi

发明人： Nikhil Bhat ,  George Choi

IPC分类号： G01D7/00 ,  G01D7/08 ,  G01N31/22

CPC分类号： A61B5/4205 ,  A61B5/0071

摘要： A method and apparatus related to a swallowing indicator for a solid object that is not intended to be ingested is disclosed. The indicator can be integrated with solid objects such as batteries or children's toys. The indicator stains the tongue, lips, or other areas of the mouth or throat when the object is swallowed, thus warning a caretaker. The indicator can be attached to or integrated with a solid object. The indicator may further comprise a bitterant.

摘要翻译： 公开了一种与不想摄入的固体物体的吞咽指示器相关的方法和装置。 指示器可以与固体物体（如电池或儿童玩具）集成。 当物体被吞咽时，指示器会污染舌头，嘴唇或嘴或喉部的其他区域，从而警告看守者。 指示器可以连接到固体物体上或与固体物体一体化。 指示剂还可以包含苦味剂。

公开(公告)号：US20070244529A1

公开(公告)日：2007-10-18

申请号：US11697172

申请日：2007-04-05

申请人： George Choi ,  Kasey Li

发明人： George Choi ,  Kasey Li

IPC分类号： A61F7/00 ,  A61F7/12 ,  A61N1/30

CPC分类号： A61N7/022 ,  A61M25/0084 ,  A61N2007/0078

摘要： Apparatus and methods for the treatment of nasal tissue, particularly the nasal turbinates, are described herein. One method for reducing the size of the inferior nasal turbinate is to apply ultrasound energy to the tissue regions beneath the surface of the turbinate tissue. One instrument may be used to deliver ultrasound energy and to provide an infusion or injection of a fluid directly into the turbinate being treated. The injected fluid can be used to bulk up the size of the turbinate to ensure that the ultrasound energy is properly delivered directly into the intended turbinate tissue. Accordingly, fluids containing anesthetics, fluids infused with analgesics, etc. may be used for pain management while other medications, such as non-steroidal drugs, steroidal drugs, anti-inflammatory drugs, anti-histamines, anti-bacterial drugs, etc., can also be used.

摘要翻译： 本文描述了用于治疗鼻组织，特别是鼻甲的装置和方法。 用于减小下鼻甲的尺寸的一种方法是将超声能量施加到鼻甲组织表面下方的组织区域。 一种仪器可用于输送超声能量，并将流体直接输入或注射到正在治疗的鼻甲中。 注射的流体可以用于增大鼻甲的尺寸，以确保超声能量被适当地输送到预期的鼻甲组织中。 因此，含有麻醉剂的流体，注入镇痛药的液体等可以用于疼痛管理，而其它药物如非甾体药物，甾体药物，抗炎药，抗组胺药，抗菌药物等， 也可以使用。

公开(公告)号：US20060185680A1

公开(公告)日：2006-08-24

申请号：US11355927

申请日：2006-02-15

申请人： Nikhil Bhat ,  Anant Hegde ,  George Choi

发明人： Nikhil Bhat ,  Anant Hegde ,  George Choi

IPC分类号： A61F5/56 ,  A61C5/14

CPC分类号： A61F5/566 ,  A61B5/0031 ,  A61B5/1076 ,  A61B5/4818 ,  A61C7/00 ,  A61F2/00 ,  A61F5/56 ,  A61N1/0519 ,  A61N1/0546 ,  A61N1/0548 ,  A61N1/3601

摘要： An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods of using the device are also disclosed. The airway implant device comprises a deformable element to control the opening of an air passageway. Preferably the deformable element is an electroactive polymer element. Energizing of the electroactive polymer element provides support for the walls of an air passageway, when the walls collapse, and thus, completely or partially opens the air passageway. Some embodiments of the invention include a sensor capable of sensing the possible occurrence of an apneic event and activating the deformable element of the airway implant device. Methods of treating airway disorders such as sleep apnea and snoring with the airway implant device are disclosed herein.

摘要翻译： 公开了一种用于在空气通道中保持和/或形成开口的气道植入装置。 还公开了使用该装置的方法。 气道植入装置包括可变形元件以控制空气通道的开口。 优选地，可变形元件是电活性聚合物元件。 电活性聚合物元件的通电为空气通道的壁提供支撑，当壁崩溃时，从而完全或部分地打开空气通道。 本发明的一些实施例包括能够感测呼吸暂停事件的可能发生并激活气道植入装置的可变形元件的传感器。 本文公开了用气道植入装置处理呼吸道疾病如睡眠呼吸暂停和打鼾的方法。