公开(公告)号：US20240293822A1

公开(公告)日：2024-09-05

申请号：US18436879

申请日：2024-02-08

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Eli N. GLEZER ,  Stephen HIGGINS ,  Sandor KOVACS ,  Sudeep KUMAR ,  Kenneth PAGE ,  Kristian ROTH ,  George SIGAL

IPC: B01L7/00 ,  B01L3/00 ,  C12Q1/686

CPC classification number: B01L7/525 ,  B01L3/5027 ,  B01L2200/027 ,  B01L2200/0605 ,  B01L2200/0621 ,  B01L2200/0631 ,  B01L2200/10 ,  B01L2200/146 ,  B01L2200/16 ,  B01L2300/0645 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0883 ,  B01L2400/0487 ,  B01L2400/0688 ,  B01L2400/0694 ,  C12Q1/686

Abstract: Assay cartridges are described that have purification, reaction, and detection zones and other fluidic components which can include sample chambers, waste chambers, conduits, vents, reagent chambers, reconstitution chambers and the like. The assay cartridges are used to conduct multiplexed nucleic acid measurements. Also described are kits including such cartridges, methods of using the same, and a reader configured to analyze an assay conducted using an assay cartridge.

公开(公告)号：US20240382969A1

公开(公告)日：2024-11-21

申请号：US18671149

申请日：2024-05-22

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. GLEZER ,  Bandele JEFFREY-COKER ,  Kenneth PAGE ,  Sandor KOVACS ,  Sudeep KUMAR ,  Kristian ROTH

IPC: B01L3/00 ,  F16K11/074

Abstract: Assay cartridges are described that have a plurality of chambers and a fluidic network that includes fluidic conduits and a multi-port valve designed to selectively connect the valve inlet and one valve outlet through a fluidic connector in the valve as the remaining valve outlets are scaled.

公开(公告)号：US20220341843A1

公开(公告)日：2022-10-27

申请号：US17733036

申请日：2022-04-29

Applicant: Meso Scale Technologies, LLC.

Inventor： Nicholas ANDERSON ,  Jeffery DEBAD ,  Eli N. GLEZER ,  Sudeep KUMAR ,  Noel LAWRENCE ,  Kenneth PAGE ,  George SIGAL ,  Sharon WEST

IPC: G01N21/05 ,  G01N21/69 ,  G01N21/76 ,  B01L3/00 ,  G01N21/03 ,  G01F23/02 ,  G01F23/292 ,  G01N1/10

Abstract: Assay cartridges are described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, thy reagent pill zones and the like. In certain embodiments, these cartridges are adapted to receive and analyze a sample collected on an applicator stick. Also described are kits including such cartridges and a cartridge reader configured to analyze an assay conducted using an assay cartridge.

公开(公告)号：US20220097072A1

公开(公告)日：2022-03-31

申请号：US17492207

申请日：2021-10-01

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. GLEZER ,  Bandele JEFFREY-COKER ,  Kenneth PAGE ,  Sandor KOVACS ,  Sudeep KUMAR ,  Kristian ROTH

IPC: B01L3/00 ,  F16K11/074

Abstract: Assay cartridges are described that have a plurality of chambers and a fluidic network that includes fluidic conduits and a multi-port valve designed to selectively connect the valve inlet and one valve outlet through a fluidic connector in the valve as the remaining valve outlets are sealed.

公开(公告)号：US20190391170A1

公开(公告)日：2019-12-26

申请号：US16319731

申请日：2017-01-20

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Manish KOCHAR ,  Peter J. BOSCO ,  Ian D. CHAMBERLIN ,  Bandele JEFFREY-COKER ,  Eric M. JONES ,  Gary l. KRIVOY ,  Aaron H. LEIMKUEHLER ,  Pei-Ming WU ,  Kim-Xuan NGUYEN ,  Pankaj OBEROI ,  Louis W. PANG ,  Jennifer PARKER ,  Victor PELLICIER ,  Nick SAMMONS ,  George SIGAL ,  Jacob WOHLSTADTER ,  Mike VOCK ,  Stanley T. SMITH ,  Carl C. STEVENS ,  Roger D. OSBORNE ,  Kenneth PAGE ,  Michael T. WADE ,  Jon WILLOUGHBY ,  Lei WANG ,  Don E. KRUEGER

IPC: G01N35/00 ,  B01L3/00 ,  B01L9/00

Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.