公开(公告)号：US09752122B2

公开(公告)日：2017-09-05

申请号：US14486850

申请日：2014-09-15

Applicant: Modern Meadow, Inc.

Inventor： Francoise Suzanne Marga ,  Brendan Patrick Purcell ,  Gabor Forgacs ,  Andras Forgacs

IPC: C12N5/077 ,  A23P10/20 ,  A23L13/00

CPC classification number: C12N5/0658 ,  A23L13/00 ,  A23P10/20 ,  A23V2002/00 ,  C12N2500/92 ,  C12N2531/00 ,  A23V2200/264

Abstract: Edible microcarriers, including microcarrier beads, microspheres and microsponges, appropriate for use in a bioreactor to culture cells that may be used to form a comestible engineered meat product. For example, the edible microcarriers described herein may include porous microcarriers that may be used to grow cells (e.g., smooth muscle cells) and may be included with the cells in the final engineered meat product, without requiring modification or removal of the cells from the microcarriers. In a particular example, the edible microcarriers may be formed of cross-linked pectin, such as pectin-thiopropionylamide (PTP), and RGD-containing polypeptide, such as thiolated cardosin A. Methods of forming edible microcarriers, methods of using the edible microcarriers to make engineered meat, and engineered meat including the edible microcarriers are also described herein.

公开(公告)号：US11913166B2

公开(公告)日：2024-02-27

申请号：US15761209

申请日：2016-09-21

Applicant: MODERN MEADOW, INC.

Inventor： Brendan Patrick Purcell ,  Gabor Forgacs

IPC: D06N3/00 ,  C12N5/00 ,  C14C3/06

CPC classification number: D06N3/0006 ,  C12N5/0068 ,  C14C3/06 ,  D06N3/00 ,  D06N3/0011 ,  C12N2533/50

Abstract: Engineered, reinforced leather materials (engineered leathers) including a composite of a fibrous matrix that has been tanned to allow crosslinking of the fibrous matrix to the collagen formed by cultured cells (e.g., fibroblasts). These engineered leathers may be referred to as fiber-reinforced biological tissue composites. Also described herein are methods of making such fiber-reinforced biological tissue composites.