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    Bit Synchronization Detection Means
    5.
    发明申请
    Bit Synchronization Detection Means 审中-公开
    位同步检测手段

    公开(公告)号：US20080037394A1

    公开(公告)日：2008-02-14

    申请号：US10557350

    申请日：2003-05-27

    申请人： Aalbert Stek ,  Cornelis Marinus Schep ,  Constant Paul Marie Jozef Baggen ,  Josephus Arnoldus Henricus Maria Kahlman

    发明人： Aalbert Stek ,  Cornelis Marinus Schep ,  Constant Paul Marie Jozef Baggen ,  Josephus Arnoldus Henricus Maria Kahlman

    IPC分类号： G11B5/09

    CPC分类号： G11B27/24 ,  G11B7/0053 ,  G11B2220/213 ,  G11B2220/218 ,  G11B2220/2525 ,  G11B2220/2541 ,  G11B2220/2545 ,  G11B2220/2562

    摘要： Detection means for detecting information in a signal, comprising integration means for integrating the signal over time such that the integration means is periodically reset at about the start time reference of a periodic time interval; and a sample&hold circuit for periodically sampling and holding the integrated signal (int) at about an end time reference of the periodic time interval and thereby delivering a further signal (fs). The detection means further comprises a chain (CHDL) of signal time delay elements, an input of the chain (CHDL) being coupled to receive the further signal (fs); and combining means (CBMNS) having combining inputs coupled to signal taps of the chain (CHDL), such that the number of the combining inputs and the position of coupling the combining inputs to the signal taps of the chain (CHDL) correspond to the information in the signal.

    摘要翻译： 用于检测信号中的信息的检测装置，包括用于随时间积分信号的积分装置，使得积分装置周期性地在周期性时间间隔的开始时间基准上复位; 以及用于在约周期时间间隔的结束时间基准周期性地采样和保持积分信号（int）并从而传送另外的信号（fs）的采样和保持电路。 所述检测装置还包括信号时间延迟元件的链（CHDL），所述链（CHDL）的输入被耦合以接收所述另外的信号（fs）; 以及具有耦合到链路（CHDL）的信号抽头的组合输入的组合装置（CBMNS），使得组合输入的数量和将组合输入耦合到链路（CHDL）的信号抽头的位置对应于信息 在信号中。

    MAGNETIC BEAD ACTUATION USING FEEDBACK FOR FTIR BIOSENSOR
    8.
    发明申请
    MAGNETIC BEAD ACTUATION USING FEEDBACK FOR FTIR BIOSENSOR 有权
    使用FTIR生物传感器反馈的磁珠执行

    公开(公告)号：US20100311183A1

    公开(公告)日：2010-12-09

    申请号：US12865864

    申请日：2009-02-02

    申请人： Josephus Arnoldus Henricus Maria Kahlman

    发明人： Josephus Arnoldus Henricus Maria Kahlman

    IPC分类号： G01N21/75

    CPC分类号： G01N33/54333 ,  G01N21/552 ,  G01N27/745 ,  G01N33/54373 ,  G01N35/0098

    摘要： The invention provides a method for controlling actuation of label particles in a biosensor device, in particular a biosensor device using frustrated total internal reflection. By applying a predetermined actuation force on the label particles and determining the effect of the applied actuation force in a binding volume or surface of a sensor cartridge of the biosensor device, a feedback control of the actuation force is applied. Furthermore, a biosensor device is provided which is adapted for forming the method according to the invention.

    摘要翻译： 本发明提供一种用于控制生物传感器装置中的标签颗粒致动的方法，特别是使用沮丧的全内反射的生物传感器装置。 通过对标签颗粒施加预定的致动力并确定所施加的致动力对生物传感器装置的传感器盒的装订体积或表面的影响，施加致动力的反馈控制。 此外，提供适于形成根据本发明的方法的生物传感器装置。

    EVANESCENT FIELD MODULATION IN A BIOSENSOR
    9.
    发明申请
    EVANESCENT FIELD MODULATION IN A BIOSENSOR 有权
    生物传感器中的EVANESCENT现场调制

    公开(公告)号：US20100290052A1

    公开(公告)日：2010-11-18

    申请号：US12810867

    申请日：2008-12-18

    申请人： Johannes Joseph Hubertina Barbara Schleipen ,  Dominique Maria Bruls ,  Josephus Arnoldus Henricus Maria Kahlman

    发明人： Johannes Joseph Hubertina Barbara Schleipen ,  Dominique Maria Bruls ,  Josephus Arnoldus Henricus Maria Kahlman

    IPC分类号： G01N21/55

    CPC分类号： G01N21/552

    摘要： The present invention provides an FTIR system comprising a first light source emitting light of a first wavelength, a sample volume with an adjacent sensor surface, a detector for detecting light reflected at said sensor surface. The sensor surface is illuminated by said first light source fulfilling the condition of total internal reflection and generating an evanescent field with a decay length within the sample volume. The system further comprises means for changing the decay length of the evanescent field and means for correlating the detected signals with the change of the decay length of the evanescent field.

    摘要翻译： 本发明提供了一种FTIR系统，包括发射第一波长的光的第一光源，具有相邻传感器表面的样品体积，用于检测在所述传感器表面反射的光的检测器。 所述传感器表面由满足全内反射条件的所述第一光源照射，并产生具有在样品体积内的衰减长度的ev逝场。 该系统还包括用于改变ev逝场的衰减长度的装置和用于使检测到的信号与ev逝场的衰减长度变化相关联的装置。

    MICROELECTRONIC SENSOR DEVICE WITH MAGNETIC FIELD GENERATOR AND CARRIER
    10.
    发明申请
    MICROELECTRONIC SENSOR DEVICE WITH MAGNETIC FIELD GENERATOR AND CARRIER 审中-公开
    具有磁场发生器和载体的微电子传感器装置

    公开(公告)号：US20100188076A1

    公开(公告)日：2010-07-29

    申请号：US12667396

    申请日：2007-10-23

    申请人： Josephus Arnoldus Henricus Maria Kahlman ,  Jeroen Veen

    发明人： Josephus Arnoldus Henricus Maria Kahlman ,  Jeroen Veen

    IPC分类号： G01N27/72

    CPC分类号： G01R33/1269 ,  B01L3/502761 ,  B01L2200/0636 ,  B01L2400/043 ,  G01N21/552 ,  G01N27/745

    摘要： The invention relates to a microelectronic sensor device for manipulating a sample in an exchangeable carrier (111), for example for optically detecting target particles (1) in a sample liquid that is provided in a sample chamber (2) of the carrier (111). The microelectronic sensor device comprises a number of n>1 magnetic field generators (141-143), e.g. electromagnetic coils, with which magnetic fields can be generated in a target region (110). A control unit (150) is provided that can determine and evaluate the mutual coupling or the self-inductance of the magnetic field generators and/or signals from magnetic field sensors attached to the carrier with respect to the presence and/or state of a carrier (111) in the target region (110). In this way, the control unit (150) can for example detect if the carrier (111) is correctly positioned in the sensor device and/or where a magnetically interactive substance (1, 120) is located.

    摘要翻译： 本发明涉及一种用于操纵可交换载体（111）中的样品的微电子传感器装置，例如用于光学检测设置在载体（111）的样品室（2）中的样品液体中的目标颗粒（1） 。 微电子传感器装置包括多个n≥1个磁场发生器（141-143），例如， 电磁线圈，可以在目标区域（110）中产生磁场。 提供控制单元（150），其可以相对于载体的存在和/或状态来确定和评估附接到载体的磁场传感器的磁场发生器和/或信号的相互耦合或自感 （111）在目标区域（110）中。 以这种方式，控制单元（150）可以例如检测载体（111）是否被正确地定位在传感器装置中和/或磁性交互物质（1,120）所在的位置。